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O papel modulador do gene AIRE - capes

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REFERÊNCIAS BIBLIOGRÁFICASPitkanen J, Doucas V, Sterns<strong>do</strong>rf T, Nakajima T, Aratani S, Jensen K, Will H,Vähämurto P, Ollila J, Vihinen M, Scott HS, Antonarakis SE, Ku<strong>do</strong>h J,Shimizu N, Krohn K, Peterson P (2000). The autoimmune regulator proteinhas transcriptional transactivating properties and interacts with thecommon coactivator CREB-binding protein. J Biol Chem. 275(22):16802-9.Pitkanen J, Peterson P (2003). Autoimmune regulator : from loss of function toautoimmunity. Genes Immunology 4: 12.Pitkänen J, Rebane A, Rowell J, Murumägi A, Ströbel P, Möll K, Saare M,Heikkilä J, Doucas V, Marx A, Peterson P (2005). Cooperative activation oftranscription by autoimmune regulator <strong>AIRE</strong> and CBP. Biochem BiophysRes Commun. 333(3):944-53.Pugliese A. (2002). Peripheral antigen-expressing cells and autoimmunity.En<strong>do</strong>crinol Metab Clin North Am. 31(2):411-30.Puthier D, Joly F, Irla M, Saade M, Victorero G, Loriod B, Nguyen C (2004). A<strong>gene</strong>ral survey of thymocyte differentiation by transcriptional analysis ofknockout mouse models. J Immunol. 173(10):6109-18.Ramialison M, Mohr E, Nal B, Saboul T, Carrier A, Tagett R, Granjeaud S,Nguyen C, Gautheret D, Jordan BR, Ferrier P (2002). Expression profilingin mouse fetal thymus reveals clusters of coordinately expressed <strong>gene</strong>sthat mark individual stages of T-cell ontogeny. Immuno<strong>gene</strong>tics.54(7):469-478.Ramsey C, Winqvist O, Puhakka L, Halonen M, Moro A, Kämpe O, Eskelin P,Pelto-Huikko M, Peltonen L (2002). Aire deficient mice develop multiplefeatures of APECED phenotype and show altered immune response. Hum.Mol. Genet. 11, 397409.Rossi SW, Jenkinson WE, Anderson G, Jenkinson EJ (2006). Clonal analysisreveals a common progenitor for thymic cortical and medullaryepithelium. Nature 441(7096):988-991.118

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