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O papel modulador do gene AIRE - capes

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REFERÊNCIAS BIBLIOGRÁFICASManley NR. 2000 Thymus organo<strong>gene</strong>sis and molecular mechanisms of thymicepithelial cell differentiation. Semin Immunol. 12(5):421-428.Manley NR, Blackburn CC. 2003 A developmental look at thymusorgano<strong>gene</strong>sis: where <strong>do</strong> the non-hematopoietic cells in the thymus comefrom? Curr Opin Immunol. 15(2):225-32.Margolin AA, Nemenman I, Basso K, Wiggins C, Stolovitzky G, Dalla Favera R,Califano A (2006) ARACNE: an algorithm for the reconstruction of <strong>gene</strong>regulatory networks in a mammalian cellular context. BMCBioinformatics. 7 Suppl 1:S7.Mathis D & Benoist C (2007) A decade of <strong>AIRE</strong>. Nat Rev Immunol. 7(8):645-50.Medzhitov R, Janeway CA (1997). Innate immunity, the virtues of a nonclonalsystem of recognition. Cell 91, 295–298.Menossi M, Cremonese N, Maron LG, Arruda P (2000). Making colony PCReasier by adding gel-loading buffer to the amplification reaction.Biotechniques 28: 424-6.Mizuochi T, Kasai M, Kokuho T, Kakiuchi T, Hirokawa K (1992). Medullary butnot cortical thymic epithelial cells present soluble antigens to helper Tcells. J. Exp. Med. 175: 1601-1605.Montecino-Rodriquez E, Min H, Dorshkind K (2005). Reevaluating currentmodels of thymic involution. Semin Immunol 17(5): 356-361.Nagamine K, Peterson P, Scott HS, Ku<strong>do</strong>h J, Minoshima S, Heino M, Krohn KJ,Lalioti MD, Mullis PE, Antonarakis SE, Kawasaki K, Asakawa S, Ito F,Shimizu N (1997). Positional cloning of the APECED <strong>gene</strong>. NatureGenetics 17: 393–398.Nagafuchi S, Katsuta H, Koyanagi-Katsuta R, Yamasaki S, Inoue Y, Shimoda K,Ikeda Y, Shin<strong>do</strong> M, Yoshida E, Matsuo T, Ohno Y, Kogawa K, Anzai K,Kurisaki H, Ku<strong>do</strong>h J, Harada M, Shimizu N (2006). Autoimmune regulator(<strong>AIRE</strong>) <strong>gene</strong> is expressed in human activated CD4+ T-cells and regulated116

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