Neurociencia del consumo y dependencia de sustancias psicoactivas
Neurociencia del consumo y dependencia de sustancias psicoactivas Neurociencia del consumo y dependencia de sustancias psicoactivas
5. BASES GENÉTICAS DE LAS FARMACODEPENDENCIASParsian A y colab. (1995) Monoamine oxidases and alcoholism. I. Studies inunrelated alcoholics and normal controls. American Journal of Medical Genetics,60:409–416.Parsian A y colab. (1997) No association between polymorphisms in the humandopamine D3 and D4 receptors genes and alcoholism. American Journal ofMedical Genetics, 74:281–285.Pesonen U y colab. (1998) Mutation screening of the 5-hydroxytryptamine7receptor gene among Finnish alcoholics and controls. Psychiatry Research,77:139–145.Picciotto MR, Wickman K (1998) Using knockout and transgenic mice to studyneurophysiology and behavior. Physiology Reviews, 78:1131–1163.Prescott CA, Kendler KS (1999) Genetic and environmental contributions toalcohol abuse and dependence in a population-based sample of male twins.American Journal of Psychiatry, 156:34–40.Prescott CA, Aggen SH, Kendler KS (1999) Sex differences in the sources ofgenetic liability to alcohol abuse and dependence in a population-based sampleof US twins. Alcoholism: Clinical and Experimental Research, 23:1136–1144.Preuss UW y colab. (2001) Impulsive traits and 5-HT2A receptor promoterpolymorphism in alcohol dependents: possible association but no influence ofpersonality disorders. Neuropsychobiology, 43:186-191.Quattrocki E, Baird A, Yurgelun-Todd D (2000) Biological aspects of the linkbetween smoking and depression. Harvard Review of Psychiatry, 8:99–110.Quinn JP (1996) Neuronal-specific gene expression — the interaction of both positiveand negative transcriptional regulators. Progress in Neurobiology, 50:363–379.Ramchandani VA, Bosron WF, Li TK (2001) Research advances in ethanolmetabolism. Pathology and Biology (París), 49:676–682.Rao Y y colab. (2000) Duplications and defects in the CYP2A6 gene: identification,genotyping, and in vivo effects on smoking. Molecular Pharmacology,58:747–755.Reed T y colab. (1994) Correlations of alcohol consumption with related covariatesand heritability estimates in older adult males over a 14- to 18-year period: theNHLBI Twin Study. Alcoholism: Clinical and Experimental Research, 18:702–710.Regev A, Jeffers L (1999) Hepatitis C and alcohol. Alcoholism: Clinical andExperimental Research, 23:1543–1551.Reich T y colab. (1998) Genome-wide search for genes affecting the risk foralcohol dependence. American Journal of Medical Genetics, 81:207–215.Rose RJ y colab. (2001) Drinking or abstaining at age 14? A genetic epidemiologicalstudy. Alcoholism: Clinical and Experimental Research, 25:1594–1604.Russell MAH (1987) Nicotine intake and its regulation by smokers. In: MartinWR y colab., eds. Advances in behavioral biology. Vol. XX. Tobacco, smoking andnicotine. Nueva York, NY, EE.UU. Plenum Press: 25–50.Saba L y colab. (2001) The R100Q mutation of the GABA(A) alpha(6) receptorsubunit may contribute to voluntary aversion to ethanol in the sNP rat line.Molecular Brain Research, 87:263–270.163
NEUROCIENCIA DEL CONSUMO Y DEPENDENCIA DE SUSTANCIAS PSICOACTIVASSaccone y colab. (2000) A genome screen of maximum number of drinks as analcoholism phenotype. American Journal of Medical Genetics, 96:632-637.Samochowiec J y colab. (1999) Association of a regulatory polymorphism in thepromoter region of the monoamine oxidase A gene with antisocial alcoholism.Psychiatry Research, 86:67–72.Sander T y colab. (1995) Dopamine D1, D2 and D3 receptor genes in alcoholdependence. Psychiatric Genetics, 5:171–176.Sander T y colab. (1999a) Association analysis of sequence variants of GABA(A)alpha6, beta2, and gamma2 gene cluster and alcohol dependence. Alcoholism:Clinical and Experimental Research, 23:427–431.Sander T y colab. (1999b) Association analysis of exonic variants of the geneencoding the GABA(B) receptor and alcohol dependence. Psychiatric Genetics,9:69–73.Sander T y colab. (2000) Genetic variation of the glutamate transporter EAAT2gene and vulnerability to alcohol dependence. Psychiatric Genetics, 10:103–107.Sauer B (1998) Inducible gene targeting in mice using the Cre/lox system.Methods, 14:381–392.Schuckit MA (2000) Genetics of the risk for alcoholism. American Journal of theAddictions, 9:103–112.Schuckit MA y colab. (1999) Selective genotyping for the role of 5-HT2A, 5-HT2C, and GABA alpha6 receptors and the serotonin transporter in the level ofresponse to alcohol: a pilot study. Biological Psychiatry, 45:647–651.Schmid H (2000) Protektive faktoren. [Factores protectores.] En: UchtenhagenA, Zieglgänsberger W, eds. Suchtmedizin: konzepte, strategien und therapeutschesmanagement. [Medicina de las adicciones: conceptos, estrategias y manejo terapéutico.]Munich, Urban y Fischer Verlag: 226–234.Schmidt LG y colab. (2000) Different allele distribution of a regulatory MAOAgene promoter polymorphism in antisocial and anxious–depressive alcoholics.Journal of Neural Transmission, 107:681–689.Sellers EM, Tyndale RF (2000) Mimicking gene defects to treat drug dependence.Annals of the New York Academy of Sciences, 909:233–246.Sellers EM, Kaplan HL, Tyndale RF (2000) Inhibition of cytochrome P4502A6increases nicotine's oral bioavailability and decreases smoking. ClinicalPharmacology and Therapeutics, 68:35–43.Sellers EM y colab. (in press) Inhibiting CYP2A6 decreases smoking and increasesthe detoxification of the procarcinogen 4-(methylnitrosamino)-(3-pyridyl)-1-butanone (NNK). Nicotine and Tobacco Research (in press).Shea SH y colab. (2001) ADH2 and alcohol-related phenotypes in AshkenazicJewish American college students. Behavior Genetics, 31:231–239.Shields PG y colab. (1998) Dopamine D4 receptors and the risk of cigarette smokingin African- Americans and Caucasians. Cancer Epidemiology and BiomarkersPreview, 7:453–458.Silverman MA y colab. (2000) Haplotypes of four novel single nucleotide polymorphismsin the nicotinic acetylcholine receptor beta2 subunit (CHRNB2) gene164
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NEUROCIENCIA DEL CONSUMO Y DEPENDENCIA DE SUSTANCIAS PSICOACTIVASSaccone y colab. (2000) A genome screen of maximum number of drinks as analcoholism phenotype. American Journal of Medical Genetics, 96:632-637.Samochowiec J y colab. (1999) Association of a regulatory polymorphism in thepromoter region of the monoamine oxidase A gene with antisocial alcoholism.Psychiatry Research, 86:67–72.San<strong>de</strong>r T y colab. (1995) Dopamine D1, D2 and D3 receptor genes in alcohol<strong>de</strong>pen<strong>de</strong>nce. Psychiatric Genetics, 5:171–176.San<strong>de</strong>r T y colab. (1999a) Association analysis of sequence variants of GABA(A)alpha6, beta2, and gamma2 gene cluster and alcohol <strong>de</strong>pen<strong>de</strong>nce. Alcoholism:Clinical and Experimental Research, 23:427–431.San<strong>de</strong>r T y colab. (1999b) Association analysis of exonic variants of the geneencoding the GABA(B) receptor and alcohol <strong>de</strong>pen<strong>de</strong>nce. Psychiatric Genetics,9:69–73.San<strong>de</strong>r T y colab. (2000) Genetic variation of the glutamate transporter EAAT2gene and vulnerability to alcohol <strong>de</strong>pen<strong>de</strong>nce. Psychiatric Genetics, 10:103–107.Sauer B (1998) Inducible gene targeting in mice using the Cre/lox system.Methods, 14:381–392.Schuckit MA (2000) Genetics of the risk for alcoholism. American Journal of theAddictions, 9:103–112.Schuckit MA y colab. (1999) Selective genotyping for the role of 5-HT2A, 5-HT2C, and GABA alpha6 receptors and the serotonin transporter in the level ofresponse to alcohol: a pilot study. Biological Psychiatry, 45:647–651.Schmid H (2000) Protektive faktoren. [Factores protectores.] En: UchtenhagenA, Zieglgänsberger W, eds. Suchtmedizin: konzepte, strategien und therapeutschesmanagement. [Medicina <strong>de</strong> las adicciones: conceptos, estrategias y manejo terapéutico.]Munich, Urban y Fischer Verlag: 226–234.Schmidt LG y colab. (2000) Different allele distribution of a regulatory MAOAgene promoter polymorphism in antisocial and anxious–<strong>de</strong>pressive alcoholics.Journal of Neural Transmission, 107:681–689.Sellers EM, Tyndale RF (2000) Mimicking gene <strong>de</strong>fects to treat drug <strong>de</strong>pen<strong>de</strong>nce.Annals of the New York Aca<strong>de</strong>my of Sciences, 909:233–246.Sellers EM, Kaplan HL, Tyndale RF (2000) Inhibition of cytochrome P4502A6increases nicotine's oral bioavailability and <strong>de</strong>creases smoking. ClinicalPharmacology and Therapeutics, 68:35–43.Sellers EM y colab. (in press) Inhibiting CYP2A6 <strong>de</strong>creases smoking and increasesthe <strong>de</strong>toxification of the procarcinogen 4-(methylnitrosamino)-(3-pyridyl)-1-butanone (NNK). Nicotine and Tobacco Research (in press).Shea SH y colab. (2001) ADH2 and alcohol-related phenotypes in AshkenazicJewish American college stu<strong>de</strong>nts. Behavior Genetics, 31:231–239.Shields PG y colab. (1998) Dopamine D4 receptors and the risk of cigarette smokingin African- Americans and Caucasians. Cancer Epi<strong>de</strong>miology and BiomarkersPreview, 7:453–458.Silverman MA y colab. (2000) Haplotypes of four novel single nucleoti<strong>de</strong> polymorphismsin the nicotinic acetylcholine receptor beta2 subunit (CHRNB2) gene164
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