Neurociencia del consumo y dependencia de sustancias psicoactivas

Neurociencia del consumo y dependencia de sustancias psicoactivas Neurociencia del consumo y dependencia de sustancias psicoactivas

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5. BASES GENÉTICAS DE LAS FARMACODEPENDENCIASMadden PA y colab. (1999) The genetics of smoking persistence in men andwomen: a multicultural study. Behavior Genetics, 29:423–431.Maes HH y colab. (1999) Tobacco, alcohol and drug use in eight- to sixteenyear-oldtwins: the Virginia Twin Study of Adolescent Behavioral Development.Journal of Studies on Alcohol, 60:293–305.Maezawa Y y colab. (1995) Alcohol-metabolizing enzyme polymorphisms and alcoholismin Japan. Alcoholism: Clinical and Experimental Research, 19:951–954.Marmot M (1997) Inequality, deprivation and alcohol use. Addiction, 92(Suppl.1):S13–S20.Marteau TM, Lerman C (2001) Genetic risk and behavioural change. BritishMedical Journal, 322:1056–1059.Maruyama K y colab. (1999) Genotypes of alcohol-metabolizing enzymes inrelation to alcoholic chronic pancreatitis in Japan. Alcoholism: Clinical andExperimental Research, 23(Suppl 4):S85–S91.Marzuk PM y colab. (1997) Poverty and fatal accidental drug overdoses ofcocaine and opiates in New York City: an ecological study. American Journal ofDrug and Alcohol Abuse, 23:221–228.Mayer P, Hollt V (2001) Allelic and somatic variations in the endogenous opioidsystem of humans. Pharmacology and Therapeutics, 91:167–177.Mayer P y colab. (1997) Association between a delta-opioid receptor gene polymorphismand heroin dependence in man. Neuroreport, 8:2547–2550.Meller WH y colab. (1988) Specific familial transmission in substance abuse.The International Journal of the Addictions, 23:1029–1039.Merette C y colab. (1999) Evidence of linkage in subtypes of alcoholism. GeneticEpidemiology, 17(Suppl. 1):S253–S258.Merikangas KR y colab. (1998) Familial transmission of substance use disorders.Archives of General Psychiatry, 55:973–979.Merlo Pich E, Chiamulera C, Carboni L (1999) Molecular mechanisms of thepositive reinforcing effect of nicotine. Behavioral Pharmacology, 10:587–596.Messina ES, Tyndale RF, Sellers EM (1997) A major role for CYP2A6 in nicotineC-oxidation by human liver microsomes. Journal of Pharmacology andExperimental Therapeutics, 282:1608–1614.Michelhaugh SK y colab. (2001) The dopamine transporter gene (SLC6A3)variable number of tandem repeats domain enhances transcription in dopamineneurons. Journal of Neurochemistry, 79:1033–1038.Mihailescu S, Drucker-Colin R (2000) Nicotine, brain nicotinic receptors, andneuropsychiatric disorders. Archives of Medical Research, 31:131–144.Mikus G y colab. (1998) Relevance of deficient CYP2D6 in opiate dependence.Pharmacogenetics, 8:565–568.Mirin SM y colab. (1991) Psychopathology in drug abusers and their families.Comprehensive Psychiatry, 32:36–51.Miyamoto M y colab. (1999) CYP2A6 gene deletion reduces susceptibility to lungcancer. Biochemical and Biophysical Research Communications, 261:658–660.161

NEUROCIENCIA DEL CONSUMO Y DEPENDENCIA DE SUSTANCIAS PSICOACTIVASMuramatsu T y colab. (1996) Association between alcoholism and the dopamineD4 receptor gene. Journal of Medical Genetics, 33:113–115.Nakajima M y colab. (1996) Role of human cytochrome P4502A6 in C-oxidationof nicotine. Drug Metabolism and Disposition, 24:1212–1217.Nakamura A y colab. (2001) Association between catechol-O-methyltransferase(COMT) polymorphism and severe alcoholic withdrawal symptoms in maleJapanese alcoholics. Addiction Biology, 6:233–238.Nakamura K y colab. (1996) Characteristics of Japanese alcoholics with the atypicalaldehyde dehydrogenase 2*2. I. A comparison of the genotypes of ALDH2,ADH2, ADH3, and cytochrome P-4502E1 between alcoholics and nonalcoholics.Alcoholism: Clinical and Experimental Research, 20:52–55.Nakamura T y colab. (1999) Association of a polymorphism of the 5HT2A receptorgene promoter region with alcohol dependence. Molecular Psychiatry, 4:85–88.Narahashi T y colab. (2001) Mechanisms of alcohol-nicotine interactions: alcoholicsversus smokers. Alcoholism: Clinical and Experimental Research, 25(Suppl.ISBRA):S152–S156.Neumark YD y colab. (1998) Association of the ADH2*2 allele with reduced ethanolconsumption in Jewish men in Israel: a pilot study. Journal of Studies on Alcohol,59:133–139.Nielsen DA y colab. (1998) A tryptophan hydroxylase gene marker for suicidalityand alcoholism. Archives of General Psychiatry, 55:593–602.Noble EP (2000) Addiction and its reward process through polymorphisms ofthe D2 dopamine receptor gene: a review. European Psychiatry, 15:79–89.Noble EP y colab. (1998a) D2 dopamine receptor and GABA(A) receptor beta3subunit genes and alcoholism. Psychiatry Research, 81:133–147.Noble EP y colab. (1998b) D2 and D4 dopamine receptor polymorphisms andpersonality. American Journal of Medical Genetics, 81:257–267.Okamoto K y colab. (2001) Effect of ALDH2 and CYP2E1 gene polymorphismson drinking behavior and alcoholic liver disease in Japanese male workers.Alcoholism: Clinical and Experimental Research, 25(Suppl.):S19–S23.Oneta CM y colab. (2002) Dynamics of cytochrome P4502E1 activity in man:induction by ethanol and disappearance during withdrawal phase. Journal ofHepatology, 36:47–52.Oscarson M y colab. (1999) Characterization and PCR-based detection of aCYP2A6 gene deletion found at a high frequency in a Chinese population. FEBSLetters, 448:105–110.Parsian A, Cloninger CR (1997) Human GABA(A) receptor alpha1 and alpha3subunits genes and alcoholism. Alcoholism: Clinical and Experimental Research,21:430–433.Parsian A, Zhang ZH (1999) Human chromosomes 11p15 and 4p12 and alcoholdependence: possible association with the GABRB1 gene. American Journalof Medical Genetics, 88:533–538.Parsian A, Cloninger CR (2001) Serotonergic pathway genes and subtypes ofalcoholism: association studies. Psychiatric Genetics, 11:89–94.162

NEUROCIENCIA DEL CONSUMO Y DEPENDENCIA DE SUSTANCIAS PSICOACTIVASMuramatsu T y colab. (1996) Association between alcoholism and the dopamineD4 receptor gene. Journal of Medical Genetics, 33:113–115.Nakajima M y colab. (1996) Role of human cytochrome P4502A6 in C-oxidationof nicotine. Drug Metabolism and Disposition, 24:1212–1217.Nakamura A y colab. (2001) Association between catechol-O-methyltransferase(COMT) polymorphism and severe alcoholic withdrawal symptoms in maleJapanese alcoholics. Addiction Biology, 6:233–238.Nakamura K y colab. (1996) Characteristics of Japanese alcoholics with the atypicalal<strong>de</strong>hy<strong>de</strong> <strong>de</strong>hydrogenase 2*2. I. A comparison of the genotypes of ALDH2,ADH2, ADH3, and cytochrome P-4502E1 between alcoholics and nonalcoholics.Alcoholism: Clinical and Experimental Research, 20:52–55.Nakamura T y colab. (1999) Association of a polymorphism of the 5HT2A receptorgene promoter region with alcohol <strong>de</strong>pen<strong>de</strong>nce. Molecular Psychiatry, 4:85–88.Narahashi T y colab. (2001) Mechanisms of alcohol-nicotine interactions: alcoholicsversus smokers. Alcoholism: Clinical and Experimental Research, 25(Suppl.ISBRA):S152–S156.Neumark YD y colab. (1998) Association of the ADH2*2 allele with reduced ethanolconsumption in Jewish men in Israel: a pilot study. Journal of Studies on Alcohol,59:133–139.Nielsen DA y colab. (1998) A tryptophan hydroxylase gene marker for suicidalityand alcoholism. Archives of General Psychiatry, 55:593–602.Noble EP (2000) Addiction and its reward process through polymorphisms ofthe D2 dopamine receptor gene: a review. European Psychiatry, 15:79–89.Noble EP y colab. (1998a) D2 dopamine receptor and GABA(A) receptor beta3subunit genes and alcoholism. Psychiatry Research, 81:133–147.Noble EP y colab. (1998b) D2 and D4 dopamine receptor polymorphisms andpersonality. American Journal of Medical Genetics, 81:257–267.Okamoto K y colab. (2001) Effect of ALDH2 and CYP2E1 gene polymorphismson drinking behavior and alcoholic liver disease in Japanese male workers.Alcoholism: Clinical and Experimental Research, 25(Suppl.):S19–S23.Oneta CM y colab. (2002) Dynamics of cytochrome P4502E1 activity in man:induction by ethanol and disappearance during withdrawal phase. Journal ofHepatology, 36:47–52.Oscarson M y colab. (1999) Characterization and PCR-based <strong>de</strong>tection of aCYP2A6 gene <strong><strong>de</strong>l</strong>etion found at a high frequency in a Chinese population. FEBSLetters, 448:105–110.Parsian A, Cloninger CR (1997) Human GABA(A) receptor alpha1 and alpha3subunits genes and alcoholism. Alcoholism: Clinical and Experimental Research,21:430–433.Parsian A, Zhang ZH (1999) Human chromosomes 11p15 and 4p12 and alcohol<strong>de</strong>pen<strong>de</strong>nce: possible association with the GABRB1 gene. American Journalof Medical Genetics, 88:533–538.Parsian A, Cloninger CR (2001) Serotonergic pathway genes and subtypes ofalcoholism: association studies. Psychiatric Genetics, 11:89–94.162

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