REVISIONES / Rev Osteoporos Metab Miner 2011 3;4:165-182179Tabla 2. Estatus <strong>de</strong> vitamina D, evaluado como niveles séricos <strong>de</strong> 25 hidroxivitamina D en poblaciónespañola (25OHD). DE: <strong>de</strong>sviación estándar. CBP: competición proteica. RIA: radioinmunoanálisis.HPLC: cromatografía líquida <strong>de</strong> alta eficienciaReferenciaPoblaciónestudiadaCiudadEstaciónEdad(años)Número25OHD 3media±DE ng/mLPrevalencianivelesséricosbajos25OHDDefiniciónnivelesséricosbajos25OHDng/mLMétodoQuesada1989Ambos sexosCasaCórdoba37º 6’Primavera27 - 4967 - 8270 - 8532322122 ± 1114 ± 615 ± 1032%68%100%15 CBPQuesada1992Ambos sexosCasaCórdoba37º 6’Primavera20 - 5960 - 79> 881311738,0 ± 1318 ± 149 ± 4,6CBPMata-Granados2008Donantes <strong>de</strong>sangreHombresMujeresCórdoba37º 6’Primavera18 - 6518 - 64116918 ± 10,515 ± 9,214%51%65%102030HPLCMezquita-Raya 2001MujeresPostmenopáusicasGranada37º 10’Invierno-Primavera61 ± 7 161 19 ± 8 39% 15 RIAAguado2000MujeresPostmenopáusicasMadrid40º 26’Invierno-Primavera47 - 66 171 13 ± 787%64%35%201510RIALips2001MujeresPostmenopáusicasOsteoporóticasEspaña43º 37ºInviernoverano64 ± 7 132 24 ± 1441,7%10,62010RIALarrosa2001Ambos sexosAncianosResi<strong>de</strong>nciaSaba<strong>de</strong>ll41º 35’61 - 96 100 10,2 ± 5,3 87% 25 RIAVaqueiro2006Ambos sexosAncianosViven en casaSaba<strong>de</strong>ll41º 35’Invierno-Primavera72 ± 5 239 17 ± 7,580%17%2510RIAGonzález-Clemente1999Ambos sexosAncianosConsultas externasBarcelona41º 23’Invierno-Primavera75 ± 6 127 34,6% 10 RIAGómez-Alonso2003Ambos sexosAncianosCasaHombresMujeresOviedo43º 22’Todoel añoInviernoverano68 ± 968 ± 9< 6565 - 74> 6513413417 ± 817 ± 972%80%72%18 RIAPérez-Llamas2008Ambos sexosAncianosResi<strong>de</strong>nciaMurcia37º 59’Todoel añoOtoñoInviernoPrimaveraverano77 ± 8 8620 ± 125 ± 1516 ± 958,2% 20 RIADocio1998NiñosCasaCantabria43º 27’Inviernoverano8 ± 2 4315 ± 529 ± 1031%80%1220RIAPérez-Castrillón2008Ancianos ambossexosViven en casaResi<strong>de</strong>nciaValladolid41º 38’Todoel año75 ± 8583 ± 719714615 ± 817 ± 73179329110201020RIAQuesada2007MujeresosteoporóticaspostmenopáusicasNo TratadasTratadasTodaEspaña43º 28’Final <strong>de</strong>Primavera71 ± 571 ± 519014622 ± 1027 ± 1111%44%76%5%29%63%102030102030HPLC
180REVISIONES / Rev Osteoporos Metab Miner 2011 3;4:165-182El coste <strong>de</strong> los tratamientos antirresortivos es tanelevado en comparación con la vitamina D, que laconsecución <strong>de</strong> niveles óptimos <strong>de</strong> 25(OH)D resultaeficiente <strong>de</strong>s<strong>de</strong> un punto <strong>de</strong> vista terapéutico.Desafortunadamente, resulta prácticamente imposible<strong>de</strong> obtener dietéticamente esos niveles óptimos<strong>de</strong> 25(OH)D por lo que <strong>de</strong>ben instaurarse la suplementaciónmediante tratamientos, que faciliten sucumplimiento.En cualquier caso, se hace imprescindible promoverpolíticas activas <strong>de</strong> salud pública, <strong>de</strong> educaciónen hábitos saludables, pero sobre todo que sepotencien a<strong>de</strong>más <strong>de</strong>l <strong>de</strong>sarrollo <strong>de</strong> alimentos funcionalessuplementados en calcio, la suplementación<strong>de</strong> modo regular con vitamina DBibliografía1. 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