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Lampe JW. 1999. Health effects of vegetables and fruit: assessing mechanisms of action in human experimental studies. Am J Clin Nutr 70:475- 490. Lancaster JR jr. 2006. Nitroxidative, nitrosative, and nitrative stress: kinetic predictions of reactive nitrogen species chemistry under biological conditions. Chem Res Toxicol 19: 1160–1174. Larrosa M, Llorach R, Espín JC, Tomás -Barberán FA. 2002. Increase of antioxidant activity of tomato juice upon functionalisation with vegetable byproduct extracts. Lebens Wiss Technol 35:532-542. Lee HJ, Cho HS, Park E, Kim S, Lee SY, Kim CS, Kim do K, Kim SJ, Chun HS. 2008. Rosmarinic acid protects human dopaminergic neuronal cells against hydrogen peroxide-induced apoptosis. Toxicology 4;250(2-3):109-15. Lee J, Koo N, Min DB. 2004. Reactive oxygen species, aging, and antioxidative nutraceuticals. Compr. Rev. Food Sci. Food Safety 3:21-33. Lee WJ, Zhu BT. 2006. Inhibition of DNA methylation by caffeic acid and chlorogenic acid, two common catechol-containing coffee polyphenols Carcinogenesis 27(2):269-277. Lev-Ari S, Strier L, Kazanov D, Madar-Shapiro L, Dvory-Sobol H, Pinchuk I, Marian B, Lichtenberg D, Arber N. 2005. Celecoxib and curcumin synergistically inhibit the growth of colorectal cancer cells. Clin Cancer Res 11:6738–6744. Li Y, Ahmed F, Ali S, Philip PA, Kucuk O, Sarkar FH. 2005. Inactivation of nuclear factor kappaB by soy isoflavone genistein contributes to increased apoptosis induced by chemotherapeutic agents in human cancer cells. Cancer Res 65:6934–6942. Lima CF, Fernandes-Ferreira M, Pereira-Wilson C. 2006. Phenolic compounds protect HepG2 cells from oxidative damage: relevance of glutathione levels. Life Sci 79(21):2056-2068. Liu LZ, Hu XW, Xia C, He J, Zhou Q, Shi X, Fang J, Jiang BH. 2006. Reactive oxygen species regulate epidermal growth factor-induced vascular endothelial growth factor and hypoxia-inducible factor-1alpha expression through activation of AKT and P70S6K1 in human ovarian cancer cells. Free Radic Biol Med 41(10):1521-3153. 73
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UNIVERSIDAD AUTÓNOMA DE NUEVO LEÓ
Page 5 and 6:
AGRADECIMIENTOS Quiero agradecer a
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AGRADECIMIENTOS INSTITUCIONALES Qui
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7.3.1 Actividad reductora (Ensayo F
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LISTA DE FIGURAS Figura Página 1.
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mg mL M mM min m nm ppm pH Rf RMN s
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1. ABSTRACT The free radicals (FRS)
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Por otra parte, los alimentos consu
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eaccionar con todo lo que esté a s
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Figura 4. Un antioxidante es un don
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• Las enzimas reparadoras del Ác
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La modificación química directa a
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3.2 Agentes Quimiopreventivos Las h
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de mama además de mostrar un efect
Page 31 and 32:
3.3 Hedeoma drummondii (Poleo) Pert
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tipo-2 el virus de la pseudorabia,
Page 35 and 36: 5. HIPÓTESIS Hedeoma drummondii y
Page 37 and 38: 7. MATERIAL Y MÉTODOS 7.1 Material
Page 39 and 40: ATCC CCL-81), esto para determinar
Page 41 and 42: El reactivo se preparó mezclando 5
Page 43 and 44: un máximo de absorción a 415 nm y
Page 45 and 46: Espectroscopia ultravioleta/visible
Page 47 and 48: hámsters dorados (Mesocricetus aur
Page 49 and 50: analizo las medidas de tendencia ce
Page 51 and 52: 8. RESULTADOS 8.1 Estudio fitoquím
Page 53 and 54: TABLA No. II Contenido de fenoles t
Page 55 and 56: Figura 14. Cromatoplaca de las frac
Page 57 and 58: TABLA No. III Condiciones de corrid
Page 59 and 60: 8.4 Estructuras de los compuestos i
Page 61 and 62: Compuesto 3D (luteoina 7- O - gluco
Page 63 and 64: determinar la selectividad, la viab
Page 65 and 66: 8.6 Efecto Antigenotóxico de los C
Page 67 and 68: 9. DISCUSIÓN En el presente trabaj
Page 69 and 70: El poleo (H. drummondii L.) mostró
Page 71 and 72: antimicrobiana (Bagamboula et al.,
Page 73 and 74: Por otra parte, el mercurio es ampl
Page 75 and 76: 10. CONCLUSIONES Los extractos met
Page 77 and 78: 12. LITERATURA CITADA Abd El-Baky H
Page 79 and 80: cyclophosphamide-induced mutagenici
Page 81 and 82: Delgado Saucedo JI, Villaseñor Gar
Page 83 and 84: Gutiérrez-Delgado C, Báez-Mendoza
Page 85: Kelloff GJ, Hawk ET, Crowell JA, Bo
Page 89 and 90: Pérez- Gastell, PL, Pérez de Alej
Page 91 and 92: Sarkar FH, Li Y. 2007. Targeting mu
Page 93 and 94: Valko M, Rhodes CJ, Moncola J, Izak
Page 95 and 96: Espectro de RMN 1 H del compuesto 3
Page 97 and 98: Espectro de Masas del compuesto con
Page 99 and 100: 13.2 RESUMEN CURRICULAR José Ezequ
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