Foco cáncer de pulmón y oncologÃa gastrointestinal
Foco cáncer de pulmón y oncologÃa gastrointestinal
Foco cáncer de pulmón y oncologÃa gastrointestinal
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Atacando el EGFR: La familia HER/erbB <br />
Ligands: <br />
EGF <br />
TGF-‐α <br />
Amphiregulin <br />
Betacellulin <br />
HB-‐EGF <br />
Epiregulin <br />
Heregulins <br />
NRG2 <br />
NRG3 <br />
Heregulins <br />
Betacellulin <br />
Cysteine-‐ <br />
rich <br />
domains <br />
HER1 <br />
EGFR <br />
erbB1 <br />
HER2 <br />
erbB2 <br />
neu <br />
HER3 <br />
erbB3 <br />
HER4 <br />
erbB4 <br />
Tyrosine-‐ <br />
kinase <br />
domains <br />
Salomon DS, et al. Crit Rev Oncol Hematol 1995;19:183–232 <br />
Woodburn JR. Pharmacol Ther 1999;82:241–50
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