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210 <strong>Haematologica</strong> (ed. esp.), volumen 85, supl. 2, octubre 2000<br />

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TERAPIA HORMONAL<br />

SUSTITUTIVA Y MODIFICACIONES<br />

DE LA HEMOSTASIA<br />

A. ESTELLÉS 1 , C. FALCÓ 1 , F. ESPAÑA 1 Y J. AZNAR 2<br />

1 Centro de Investigación. 2 Departamento de Biopatología<br />

Clínica. Hospital La Fe. Valencia.<br />

Introducción<br />

La menopausia supone un estado de disminución<br />

estrogénica que origina una serie de cambios, tanto<br />

en el perfil lipídico como en el flujo sanguíneo y en la<br />

hemostasia, que pueden favorecer el desarrollo de la<br />

enfermedad cardiovascular 1-5 .<br />

Las modificaciones que se observan en la menopausia<br />

debidas al déficit de estrógenos se pueden

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