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한국 성인 천식의 진료 지침 - 대한내과학회

한국 성인 천식의 진료 지침 - 대한내과학회

한국 성인 천식의 진료 지침 - 대한내과학회

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<strong>천식의</strong> 치료 약제 47<br />

었고 반생리적인 호흡법을 이용한 이후의 두 연구에서 증상완화제와 흡입 스테로이드제 사용군<br />

과 유사한 결과를 보였는데 이러한 방법에 의해 환자가 자각하는 호전에는 생리적인 인자가 아<br />

닌 다른 인자가 관여하는 것으로 보인다. 컴프리(comfrey)라는 식물은 약초 차의 형태나 뿌리를<br />

이용한 가루의 형태로 판매되는데 간정맥폐색증을 유발할 수 있어 사용이 금지되고 있다. 이들<br />

에 의한 독성은 pyrrolozodone계 알칼로이드의 존재와 관련이 있다.<br />

••참고문헌<br />

111 Juniper EF, Kline PA, Vanzieleghem MA, Ramsdale EH, O’Byrne PM, Hargreave FE. Effect of<br />

long-term treatment with an inhaled corticosteroid (budesonide) on airway hyperresponsiveness<br />

and clinical asthma in nonsteroid-dependent asthmatics. Am Rev Respir Dis 1990;142:832.<br />

222 Pauwels RA, Lofdahl CG, Postma DS, Tattersfield AE, O’Byrne P, Barnes PJ, et al. Effect of<br />

inhaled formoterol and budesonide on exacerbations of asthma. Formoterol and Corticosteroids<br />

Establishing Therapy (FACET) International Study Group. N Engl J Med 1997;337:1405.<br />

333 Suissa S, Ernst P, Benayoun S, Baltzan M, Cai B. Low-dose inhaled corticosteroids and the<br />

prevention of death from asthma. N Engl J Med 2000;343:332.<br />

444 Waalkens HJ, Van Essen-Zandvliet EE, Hughes MD, Gerritsen J, Duiverman EJ, Knol K, et<br />

al. Cessation of long-term treatment with inhaled corticosteroid (budesonide) in children<br />

with asthma results in deterioration. The Dutch CNSLD Study Group. Am Rev Respir Dis<br />

1993;148:1252.<br />

555 Dicpinigaitis PV, Dobkin JB, Reichel J. Antitussive effect of the leukotriene receptor antagonist<br />

zafirlukast in subjects with cough-variant asthma. J Asthma 2002;39:291.<br />

666 Drazen JM, Israel E, O’Byrne PM. Treatment of asthma with drugs modifying the leukotriene<br />

pathway. N Engl J Med 1999;340:197.<br />

777 Barnes NC, Miller CJ. Effect of leukotriene receptor antagonist therapy on the risk of asthma<br />

exacerbations in patients with mild to moderate asthma: an integrated analysis of zafirlukast<br />

trials. Thorax 2000;55:478.<br />

888 Lazarus SC, Boushey HA, Fahy JV, Chinchilli VM, Lemanske RF Jr, Sorkness CA, et al. Longacting<br />

beta2-agonist monotherapy vs continued therapy with inhaled corticosteroids in patients<br />

with persistent asthma: a randomized controlled trial. JAMA 2001;285:2583.<br />

999 Shrewsbury S, Pyke S, Britton M. Meta-analysis of increased dose of inhaled steroid or addition<br />

of salmeterol in symptomatic asthma (MIASMA). BMJ 2000;320:1368.<br />

1111 Woolcock A, Lundback B, Ringdal N, Jacques LA. Comparison of addition of salmeterol to<br />

inhaled steroids with doubling of the dose of inhaled steroids. Am J Respir Crit Care Med<br />

1996;153:1481.<br />

1111 Goldstein MF, Fallon JJ Jr, Harning R. Chronic glucocorticoid therapy-induced osteoporosis in<br />

patients with obstructive lung disease. Chest 1999;116:1733.<br />

1111 Rossouw JE, Anderson GL, Prentice RL, LaCroix AZ, Kooperberg C, Stefanick ML, et al. Risks<br />

and benefits of estrogen plus progestin in healthy postmenopausal women: principal results<br />

From the Women’s Health Initiative randomized controlled trial. JAMA 2002;288:321.<br />

1111 Brown JP, Josse RG. 2002 clinical practice guidelines for the diagnosis and management of<br />

osteoporosis in Canada. CMAJ 2002;167:S1.

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