Enfermedades mitocondriales - Asociación Española para el ...
Enfermedades mitocondriales - Asociación Española para el ...
Enfermedades mitocondriales - Asociación Española para el ...
Create successful ePaper yourself
Turn your PDF publications into a flip-book with our unique Google optimized e-Paper software.
<strong>Enfermedades</strong> <strong>mitocondriales</strong><br />
solucionan <strong>el</strong> defecto, sino que tratan de corregir parcialmente<br />
<strong>el</strong> defecto bioquímico subyacente. Es importante<br />
monitorizar las concentraciones de los fármacos<br />
aplicados en la terapia, no sólo <strong>para</strong> prevenir los efectos<br />
secundarios que se pudieran desencadenar, sino también<br />
<strong>para</strong> conocer mejor la r<strong>el</strong>ación dosis d<strong>el</strong> fármacoefecto<br />
terapéutico.<br />
Referencias<br />
1. Bernier FP, Boneh A, Dennett X, Chow CW, Cleary MA,<br />
Thorburn DR. Diagnostic criteria for respiratory chain<br />
disorders in adults and children. Neurology 2002; 59: 1406-<br />
1411.<br />
2. Artuch R, Pineda M, Vilaseca MA, Briones P, Ribes A,<br />
Colomer J, Vernet A, Campistol J. Respiratory chain and<br />
pyruvate metabolism deficiencies in pediatric patients:<br />
evaluation of biochemical tests for s<strong>el</strong>ective screening.<br />
Rev Neurol. 1998; 26(149):38-42.<br />
3. Eng<strong>el</strong> WK, Cunningham GC. Rapid examination of muscle<br />
tissue: An improved trichrome stain method for fresh<br />
frozen biopsy sections. Neurology 1963; 13:919-26.<br />
4. Campos Y, Arenas J, Cab<strong>el</strong>lo A, et al. Respiratory chain<br />
enzyme defects in patients with idiopathic inflammatory<br />
myopathy. Ann Rheum Dis 1995b; 54:491-93.<br />
5. González-Crespo R, Arenas J, Gómez-Reino J, et al. Muscle<br />
dysfunction in ederly individuals with hip fracture. J<br />
Rheumatol 1999; 26:2229-32.<br />
6. Holt IJ, Harding AE, Petty RK, et al. A new mitochondrial<br />
disease associated with mitochondrial DNA heteroplasmy.<br />
Am J Hum Genet 1990 ; 46:428-33.<br />
7. Cab<strong>el</strong>lo A, Navarro C, Ricoy JR. Alteraciones morfológicas<br />
de las miopatías <strong>mitocondriales</strong>. Rev Neurol<br />
1998; 26:44-9.<br />
8. Bonilla E, Sciacco M, Tanji K, et al. New morphological<br />
approaches to the study of mitochondrial encephalomyopathies.<br />
Brain Pathol 1992; 2:113-19.<br />
9. DiMauro S, Nicholson JF, Hays AP, et al. Benign infantile<br />
micochondrial myopathy due to reversible cytochrome c<br />
oxidase deficiency. Ann Neurol 1983; 14:226-34.<br />
10. Tritschler HJ, Andreetta F, Moraes CT, et al. Mitochondrial<br />
myopathy of childhood associated with depletion of mitochondrial<br />
DNA. Neurology 1992; 42:209-17.<br />
422
Change language