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Novocastratm Ready-to-Use Mouse Monoclonal Antibody CD20

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La interpretación clínica de cualquier tinción o de su ausencia debe complementarse con estudios morfológicos, con el uso de los<br />

controles adecuados, y un ana<strong>to</strong>mopatólogo cualifi cado debe evaluarla en el contex<strong>to</strong> del his<strong>to</strong>rial clínico del paciente y de otras<br />

pruebas diagnósticas.<br />

Los anticuerpos de Leica Biosystems Newcastle Ltd son para utilizarlos, según se indique, con secciones congeladas o incluidas<br />

en parafi na, con requisi<strong>to</strong>s de fi jación específi cos. Puede producirse una expresión inesperada del antígeno, especialmente en las<br />

neoplasias. La interpretación clínica de cualquier sección de tejido teñida debe incluir un análisis morfológico y la evaluación de los<br />

controles apropiados.<br />

Bibliografía - General<br />

1. National Committee for Clinical Labora<strong>to</strong>ry Standards (NCCLS). Protection of labora<strong>to</strong>ry workers from infectious diseases transmitted<br />

by blood and tissue; proposed guideline. Villanova, P.A. 1991; 7(9). Order code M29-P.<br />

2. Battifora H. Diagnostic uses of antibodies <strong>to</strong> keratins: a review and immunohis<strong>to</strong>chemical comparison of seven monoclonal and<br />

three polyclonal antibodies. Progress in Surgical Pathology. 6:1–15. eds. Fenoglio-Preiser C, Wolff CM, Rilke F. Field & Wood, Inc.,<br />

Philadelphia.<br />

3. Nadji M, Morales AR. Immunoperoxidase, part I: the techniques and pitfalls. Labora<strong>to</strong>ry Medicine. 1983; 14:767.<br />

4. Omata M, Liew CT, Ashcavai M, Peters RL. Nonimmunologic binding of horseradish peroxidase <strong>to</strong> hepatitis B surface antigen: a<br />

possible source of error in immunohis<strong>to</strong>chemistry. American Journal of Clinical Pathology. 1980; 73:626.<br />

5. Chen CC, Raikow RB, Sonmez-Alpan E et al. Classifi cation of small B-cell lymphoid neoplasms using a paraffi n section<br />

immunohis<strong>to</strong>chemical panel. Appl Immunohis<strong>to</strong>chem Mol Morphol. 2000; 8(1):1–11.<br />

6. Hsi ED, Eisbruch A, Greenson JK et al. Classifi cation of primary gastric lymphomas according <strong>to</strong> his<strong>to</strong>logic features. American<br />

Journal of Surgical Pathology. 1998; 22(1):17–27.<br />

7. Chuang SS and Li CY. <strong>Use</strong>ful panel of antibodies for the classifi cation of acute leukemia by immunohis<strong>to</strong>chemical methods in bone<br />

marrow trephine biopsy specimens. American Journal of Clinical Pathology. 1997; 107(4):410–418.<br />

8. Mason DY, Comans-Bitter WM, Cordell JL et al. <strong>Antibody</strong> L26 recognises an intracellular epi<strong>to</strong>pe on the B-cell-associated <strong>CD20</strong><br />

antigen. American Journal of Pathology. 1990; 136(6):1215–1222.<br />

9. Cartun RW, Coles FB and Pastuszak WT. Utilization of monoclonal antibody L26 in the identifi cation and confi rmation of B-cell<br />

lymphomas. A sensitive and specifi c marker applicable <strong>to</strong> formalin and B5-fi xed, paraffi n-embedded tissues. American Journal of<br />

Pathology. 1987; 129(3):415–421.<br />

10. Nor<strong>to</strong>n AJ and Isaacson PG. <strong>Monoclonal</strong> antibody L26: an antibody that is reactive with normal and neoplastic B lymphocytes in<br />

routinely fi xed and paraffi n wax embedded tissues. Journal of Clinical Pathology. 1987; 40:1405–1412.<br />

11. Ishii Y, Takami T, Yuasa H et al. Two distinct antigen systems in human B lymphocytes: identifi cation of cell surface and intracellular<br />

antigens using monoclonal antibodies. Clinical Experimental Immunology. 1984; 58:183–192.<br />

Correcciones A La Publicación Anterior<br />

No aplicable.<br />

Fecha De Publicación<br />

23 de junio de 2008 (RTU-<strong>CD20</strong>-L26/CE/UK)<br />

RTU-<strong>CD20</strong>-L26<br />

Page 23

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