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to get the file - OCW CEU

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H 3CO<br />

4-fenilbutilaminas: verapamilo, propoxifeno<br />

H 3CO H 3CO<br />

H 3CO<br />

CH 2 CN<br />

NaNH 2<br />

H3CO CH<br />

CN<br />

CH(CH3) 2<br />

H 3CO<br />

H 3CO<br />

CH(CH 3) 2<br />

C<br />

CN<br />

CH 2CH 2CH 2<br />

Verapamilo<br />

H 3CO<br />

1. NaNH2 2. Cl(CH2) 3<br />

N<br />

CH 3<br />

(CH 2) 2<br />

CH<br />

CH3 N (CH2) 2<br />

OCH 3<br />

CN<br />

OCH 3<br />

ClCH(CH 3) 2<br />

OCH 3<br />

OCH 3<br />

Bloqueo de los<br />

canales de Ca<br />

Antianginoso<br />

Antiarrítmico<br />

54

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