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●Sulfonilureas: Tolbutamida<br />

H 3C<br />

O<br />

S<br />

O<br />

Arilsulfonamida<br />

O<br />

H 3C S<br />

O<br />

H<br />

N<br />

H<br />

NH 2<br />

O<br />

C<br />

O<br />

H 3C S<br />

O<br />

+ O C N<br />

N<br />

NH<br />

isociana<strong>to</strong> de butilo<br />

O<br />

C<br />

Bu<br />

Bu H 3C S<br />

NH(CH 2) 3CH 3<br />

Estrategia B<br />

O<br />

O<br />

H<br />

N<br />

H<br />

O<br />

C<br />

N Bu<br />

112

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