to get the file - OCW CEU
to get the file - OCW CEU
to get the file - OCW CEU
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● Sulfonilureas: TOLBUTAMIDA<br />
antidiabético oral estimulación de la liberación de insulina<br />
Estrategia A<br />
H 3C<br />
O<br />
S<br />
Arilsulfonamida<br />
H 3C<br />
O<br />
O<br />
S<br />
O<br />
NH 2<br />
Éster N-arilsulfonilcarbámico<br />
O<br />
H 3C S<br />
O<br />
NH<br />
NH<br />
O<br />
O<br />
C<br />
C<br />
O<br />
+ Cl C<br />
OEt<br />
OEt<br />
cloroformia<strong>to</strong> de etilo<br />
NH(CH 2) 3CH 3<br />
Na 2CO 3<br />
NH 2 (CH 2) 3CH 3<br />
111
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