to get the file - OCW CEU
to get the file - OCW CEU
to get the file - OCW CEU
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●Sulfonamidas antibacterianas<br />
- Estrategia sintética a partir de anilina<br />
H 2N<br />
Anilina<br />
H3C C HN<br />
amida<br />
Cl S<br />
O<br />
O<br />
EtO<br />
H3C C<br />
O<br />
C<br />
HN<br />
HN<br />
SO2Cl NH2R aminolisis<br />
EtO<br />
H3C C<br />
O<br />
C<br />
HN<br />
HN<br />
SO2NHR NaOH<br />
desprotección<br />
O<br />
Cl C<br />
o<br />
OEt<br />
Ac2O O<br />
EtO C HN<br />
carbama<strong>to</strong><br />
O<br />
H 2N SO 2NHR<br />
sulfonamida<br />
O<br />
O<br />
OH<br />
clorosulfonación<br />
108
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