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2012-02-21-Salud cardiovascular y Antioxidantes - Universidad de ...

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Fuentes <strong>de</strong> EROs en la vasculatura<br />

•Ang II, ET-1, Trombina<br />

•IL-1, TNF-α<br />

•PDGF, IGF, EGF<br />

NOX-4<br />

•Ocupación <strong>de</strong> LOX-1<br />

•Fuerza <strong>de</strong> distensión<br />

parietal<br />

anti-gp91 phox<br />

anti-tubulina<br />

O 2<br />

gp91 phox<br />

p67<br />

p40<br />

p22<br />

p47<br />

Rac<br />

NADPH oxidasa<br />

-<br />

O2 •Xantina oxidasa<br />

•Respiración mitocondrial<br />

•Ciclooxigenasa<br />

•Lipooxigenasa<br />

•Citocromo P450<br />

•eNOS III disfuncional<br />

Citoesqueleto.

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