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class II chains during assembly in normal spleen cells. J Biol Chem 270: 10475-10481, 1995. Martínez-Laso J, De Juan D, Martínez-Quiles N, Gómez- Casado E, Cuadrado E, y Arnaiz-Villena A. The contribution of the HLA-A, -B, -C and -DR, -DQ DNA typing to the study of the origins of Spaniards and Basques. Tissue Antigens 45: 237- 245, 1995. Martínez-Laso J, Gazit E, Gómez-Casado E, Morales P, Martínez-Quiles N, Alvarez M, Martín-Villa JM, Fernández V, y Arnaiz-Villena A. HLA-DR and DQ polymorphism in Ashkenazi and non- Ashkenazi Jews: comparison with other Mediterraneans. Tissue Antigens 47: 63-71, 1996. Mason PM, y Parham P. HLA class I region sequences, 1998. Tissue Antigens 51: 417-466, 1998. Matsumura M, Fremont DH, Peterson PA, y Wilson IA. Emerging principles for the recognition of peptide antigens by MHC class I molecules. Science 257: 927-934, 1992. Matsushima G, Itoh-Lindstrom Y, y Ting JPY. Activation of the HLA-DRA gene in primary human T lymphocytes: novel usage of TATA and the X and Y promoter elements. Mol Cell Biol 12: 5610- 5619, 1992. McCauley JF, Schaber GG, Breed CS, y Grotier MJ. Subsurface valleys and geoarcheology of eastern Sahara revealed by shuttle radar. Science 218: 1004-1020, 1982. McEvedy C, y Jones R. Atlas of World Population History. London: Harmondsworth Penguin Books, p 99, 1978. McKenzie D. Creta y el pre-helénico europeo, Madrid: Studio Editions, ME eds, 1996. Mehra NK, Rajalingam R, Kanga U, McEnemy L, Cullen M, Agarwal S, Middleton D, Pollack MS, Amirzargar A y Singal DP. Genetic diversity of HLA in the populations of India, Sri Lanka and Iran. En: Genetic diversity of HLA Functional and Medical implications. Charron D (ed). Vol I, Paris: EDK, pp 314-320, 1997. Meiklejohn C, Schentag CT, Venema A, y Key P. Socioeconomic change and patterns of pathology and variation in the Mesolithic and Neolithic of Western Europe: Some suggestions. En: Paleopathology at the Origins of Agriculture. Cohen MN and Armelagos GJ (eds). Orlando: Academic Press, pp 75-100, 1984. Melian A, Beckman EM, Porcelli SA, y Brenner MB. Antigen presentations by CD1 and MHC-encoded class I like molecules. Curr Opin Immunol 8: 82- 88, 1996. Eduardo Gómez Casado Bibliografía 146 Melnick J, y Argon Y. Molecular chaperones and the biosynthesis of antigen receptors. Immunol Today 16: 243-250, 1995. Mittal KK, Mickey MR, Singal DP, y Terasaki PI. Serotyping for homotransplantation XVIII. Refinement of microdroplet lymphocyte cytotoxicity test. Transplantation 6: 913-917, 1968. Momburg F, Roelse J, Hämmerling GJ, y Neefjes JJ. Peptide size selection by the major histocompatibility complex-encoded peptide transport. J Exp Med 179: 1613-1623, 1994. Moreno CS, Emery P, West JE, Durand B, Reith W, Mach B, y Boss JM. Purified X2BP cooperatively binds the class II MHC X box region in the presence of purified RFX the X box factor deficient in the bare lymphocyte syndrome. J Immunol 155: 4313-4321, 1995. N Nei M. Genetic distances between populations. Am Nat 106: 283, 1972. Norbury CC, Hewlett LJ, Prescott AR, Shastri N, y Watts C. Class I MHC presentation of exogenous soluble antigen via macropinocytosis in bone marrow macrophages. Immunity 3: 783-791, 1995. Nossner E, y Parham P. Species-specific differences in chaperone interaction of human and mouse major histocompatibility complex class I molecules. J Exp Med 181: 327-337, 1995. O Otta T. Dispan: genetic distance and phylogenetic analysis. Pennsylvania State University, 1993. O'Callaghan CA, Tormo J, Willcox BE, Blundell CD, Jakobsen BK, Stuart DI, McMichael AJ, Bell JI, y Jones EY. Production, crystallization, and preliminary X-ray of the human MHC class Ib molecule HLA-E. Protein Sci 7: 1264-1266, 1998. Ozato K. Control of MHC class I gene expression in modulation of MHC antigen expression and disease. Cambridge Univerdity Press, 1995. P Parham P, Lomen CE, y Lawlor DA. Nature of polymorphism in HLA-A, -B y -C molecules. Proc Natl Acad Sci USA 85: 4005-4009, 1988.
Pieters J, Bakke O, y Dobberstein B. The MHC class II associated invariant chain contains two endosomal targeting signals within its cytoplasmic tail. J Cell Sci 106: 831-842, 1993. Pieters J. MHC class II restricted antigen presentation. Curr Opin Inmunol 9: 89-96, 1997. Pinto F, González AM, Hernández M, Larruga JM, y Cabrera VM. Genetic relationship between the Canary Islanders and their African and Spanish ancestors inferred from mitochondrial DNA sequences. Ann Hum Genet 60: 321-330, 1996. Ploegh HL, Orr HT, y Strominger JL. Major histocompatibility antigens: the human (HLA-A, - B, -C) and murine (H-2K, H-2A) class I molecules. Cell 24: 287-299, 1981. Pozzo G, Ciullo M, Autiero M, y Guardiola J. Control of nucleo-cytoplasmic HLA-DRA mRNA partitioning by interaction of a retention signal with compartmentalized proteins. J Mol Biol 240: 193- 204, 1994. Eduardo Gómez Casado R Rachid Raha A. Imazighen del Magreb entre oriente y occidente (Introducción a los bereberes). Granada: AR. Raha, 1994. Radley E, Alderton RP, Kelly A, Trowsdale J, y Beck S. Genomic organization of HLA-DMA and HLA- DMB. Comparison of the gene organization of all six class II families in the human MHC. J Biol Chem 22, 269: 18834-18838, 1994. Rammensee HG, Falk K, y Rötzschke O. Peptide naturally presented by MHC class I molecule. Ann Rev Immunol 11: 213-244, 1993. Rammensee HG, Friede T, y Stephanovic S. MHC ligands and peptide motifs: first listing. Immunogenetics 41: 178-228, 1995. Ramos-Oliveira J. Historia de España: La prehistoria. Mexico: Oasis, Vol 1, pp 199, 202, 273, 346, 348, y 437, 1971a. Ramos-Oliveira J. Historia de España: La antigüedad. Mexico: Oasis, Vol 2, p 278, 1971b. Realini C, Dubiel W, Pratt G, Ferrel K, y Rechsteiner M. Molecular cloning and expression of αinterferon-inducible activator of the multicatalytic proteasome. J Biol Chem 269: 20727-20732, 1994. Reith W, Satola S, Herrero-Sanchez C, Amaldi I, Lisowska-Grospierre B, Griscelli C, Hadam MR, y Mach B. Congenital immunodeficiency with a regulatory defect in MHC class II gene Bibliografía 147 expression lacks a specific HLA-DR promoter binding protein, RF-X. Cell 53: 897-906, 1988. Renfrew C. Archeology and Language: The puzzle of Indo- European Origins. London: Jonathan Cape, 1987. Roche PA, Marks MS, y Cresswell P. Formation of a ninesubunit complex by HLA class II glycoproteins and the invariant chain. Nature 354: 392-394, 1991. Roitberg-Tambur A, Wittcs CS, Friedmann A, Safirman C, Sherman L, Battat S, Nelken D, y Brautbar C. Comparative analysis of HLA polymorphism at the serologic and molecular level in Moroccan and Ashkenazi Jews. Tissue Antigens 46: 104- 110, 1995. Ronchi A, Bellorini M, Mongelli N, y Mantovani R. CCAAT-box binding protein NF-Y (CBF, CP1) recognizes the minor groove and distorts DNA. Nucleic Acids Res 23: 4565-4572, 1995. Rudensky AY, Preston-Hurlburt P, Hong SC, Barlow A, y Janeway CA Jr. Sequence analysis of peptides bound to MHC class II molecules. Nature 353: 622-627, 1991. Rudensky AY, Preston-Hurlburt P, Al-Ramadi BK, Rothbard J, y Janeway CA Jr. Truncation variants of peptides isolated from MHC class II molecules suggest sequence motifs. Nature 359: 429-431, 1992. Ruhlen M. The Basque language is included in the Dene- Caucasian language family. En: Prehistoric Iberia: Genetics, Anthropology and Linguistics. Arnaiz-Villena A (ed). Kluver, 2000. S Sadasivan B, Lehner PJ, Ortman B, Spies T, y Cresswel P. Roles for calreticulin and a novel glycoprotein, tapasin, in the interaction of MHC class I molecules with TAP. Immunity 5: 103-114, 1996. Saiki RK, Scharf S, Falaona F, Mullis KB, Horn GT, Erlich H, y Arnheim M. Enzymatic amplification of βglobin genomic sequences and restriction site analysis for diagnosis of sickle cell anemia. Science 230: 1350-1354, 1985. Saitou N, y Nei M. The neighbor-joining method: A new method for reconstructing phylogenetic trees. Mol Biol Evol 4: 406-425, 1987. Saji M, Moriarte J, Ban T, Singer D, y Kohn L. MHC class gene expression in rat thyroid cells is regulated by hormones, Methimazole and Iodine as well as Interferon. J Clin Endocrinol Metab 75: 871-878, 1992.
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UNIVERSIDAD COMPLUTENSE DE MADRID F
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Don Antonio Arnáiz Villena, Doctor
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AGRADECIMIENTOS Deseo hacer constar
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INTRODUCCIÓN I. EL SISTEMA PRINCIP
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5. Amplificación y oligotipaje de
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INTRODUCCIÓN
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Eduardo Gómez Casado Introducción
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KE2 100 200 300 400 500 600 700 800
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α1 a b β2 microglobulina Eduardo
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5.2. Estructura génica de los ant
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6. ESTRUCTURA DE LOS ANTÍGENOS HLA
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6.3. Estructura génica de los ant
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Eduardo Gómez Casado Figura 19. Di
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4. LOS PRE-MICÉNICOS: FIN DEL IMPE
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6. ANTECEDENTES GENÉTICOS Y CULTUR
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OBJETIVOS
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Eduardo Gómez Casado Objetivos 53
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1. POBLACIÓN ESTUDIADA. 1.1. SELEC
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3.- Elongación o polimerización:
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a) b) 5'AE1c Eduardo Gómez Casado
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Tabla 6. Oligonucleótidos empleado
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Tabla 7 (Cont.). Oligonucleótidos
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El proceso de revelado por quimiolu
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- 35 ciclos de las siguientes etapa
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Alemania). Este se basa en la adsor
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6.1.5. Purificación de recombinant
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de la cubeta del secuenciador autom
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suplir este inconveniente se establ
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λ Tampón de carga Se mezcla (V:V)
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Eduardo Gómez Casado Resultados 75
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Tabla 10. Alelos HLA de clase I y I
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Clayton y Lonjou 1997, y referencia
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Tabla 13. Poblaciones comparadas en
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Page 109 and 110: Griegos (Ática) 0.4 Eduardo Gómez
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Page 145 and 146: lancos y negros (n=100.000). 2- Neg
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Page 167 and 168: Anexo II 153 ARTÍCULOS ORIGINALES
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