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GENIO Y FIGURA DE LA BETAÍNA ALDEHÍDO DESHIDROGENASA

GENIO Y FIGURA DE LA BETAÍNA ALDEHÍDO DESHIDROGENASA

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MENSAJE BIOQUÍMICO, Vol. XXVIII (2004)<br />

Agradecimientos<br />

Los trabajos de nuestro grupo aquí descritos se realizaron con la colaboración entusiasta<br />

y sumamente valiosa de numerosos estudiantes, coautores de los artículos citados. Fueron<br />

apoyados financieramente por DGAPA (IN210198, IN221001) y CONACYT (1713-N9209,<br />

2552P-N9209 y 37820-N9209).<br />

Referencias<br />

1. Valenzuela-Soto EM y Muñoz-Clares RA (1994). Purification and properties of betaine aldehyde<br />

dehydrogenase extracted from detached leaves of Amaranthus hypochondriacus L. subjected to<br />

water deficit. J Plant Physiol 143: 145-152.<br />

2. Guzmán-Partida AM y Valenzuela-Soto EM (1998). Porcine kidney betaine aldehyde<br />

dehydrogenase: purification and properties. Comp Biochem Biophys part B 119: 485-491.<br />

3. Nagasawa T, Kawabata Y, Tani Y y Ogata K (1976). Purification and characterization of betaine<br />

aldehyde dehydrogenase from Pseudomonas aeruginosa A-16. Agr Biol Chem 40: 1743-1749.<br />

4. Vojtechová M, Hanson AD y Muñoz-Clares RA (1997). Betaine aldehyde dehydrogenase from<br />

amaranth leaves efficiently catalyzes the NAD + -dependent oxidation of<br />

dymethylsulfoniopropionaldehyde to dimethylsulfoniopropionate. Arch Biochem Biophys 337: 81-<br />

88.<br />

5. Johansson K, El-Ahmad M, Ramaswamy S, Hjelmqvist L, Jornvall H y Eklund H (1998). Structure<br />

of betaine aldehyde dehydrogenase at 2.1 Å resolution. Prot Sci 7: 2106-2117.<br />

6. Velasco-García R, Mújica-Jiménez C, Mendoza-Hernández G y Muñoz-Clares RA (1999). Rapid<br />

purification and properties of betaine aldehyde dehydrogenase from Pseudomonas aeruginosa. J<br />

Bacteriol 181: 1292-1300.<br />

7. Falkenberg P y Stroem AR (1990). Purification and characterization of osmoregulatory betaine<br />

aldehyde dehydrogenase from Escherichia coli. Biochim Biophys Acta 1034: 253-259.<br />

8. Valenzuela-Soto E M y Muñoz-Clares RA (1993). Betaine aldehyde dehydrogenase from leaves of<br />

Amaranthus hypochondriacus L. exhibits an Iso ordered Bi Bi steady state mechanism. J Biol Chem<br />

268: 23818-23824. Additions and Corrections (1994) 268: 4692<br />

9. Figueroa-Soto CG y Valenzuela-Soto EM (2000). Kinetic study of porcine kidney betaine aldehyde<br />

dehydrogenase. Biochem Biophys Res Commun 269: 596-603.<br />

10. Velasco-García R, González-Segura L y Muñoz-Clares RA (2000). Steady-state kinetic mechanism<br />

of NADP + - and NAD + -dependent reactions catalyzed by betaine aldehyde dehydrogenase from<br />

Pseudomonas aeruginosa. Biochem J 352: 675-683.<br />

11. Cleland WW (1963). The kinetics of enzyme-catalyzed reactions with two or more substrates or<br />

products. Biochim Biophys Acta 67: 104-137.<br />

12. Galinski EA y Truper HG (1994). Microbial behaviour in salt-stressed ecosystems. FEMS Microbiol<br />

Rev 15: 95-108.<br />

13. Rhodes D y Hanson AD (1993). Quaternary ammonium and tertiary sulfonium compounds in higher<br />

plants. Annu Rev Plant Physiol 44: 357-384.<br />

14. Grunewald RW y Eckstein A (1985). Osmotic regulation of the betaine metabolism in inmortalized<br />

renal cells. Kidney Int 48: 1714-1720.<br />

15. Pollard A y Wyn Jones RG (1979). Enzyme activities in concentrated solutions of glycine betaine<br />

and other solutes. Planta 144: 291-298.<br />

16. Lippert K y Galinski EA (1992). Enzyme stabilization by ectoine-type compatible solutes: protection<br />

against heating, freezing and drying. Appl Microbiol Biotechnol 37: 61-65.<br />

17. Niculescu MD y Zeisel SH (2002). Diet, methyl donors and DNA methylation: interactions between<br />

dietary folate, methionine and choline. J Nutr 132: 2333S-2335S.<br />

18. Steenge GR, Verhoef P y Katan MB (2003). Betaine supplementation lowers plasma hpmocysteine<br />

in healthy men and women. J Nutr 133:1291-1295.<br />

19. Mangiagalli A, Samuele A, Armentero MT, Bazzini E, Nappi G y Blandini F (2004). Effects of<br />

homocysteine on apoptosis-related proteins and anti-oxidant systems in isolated human<br />

lymphocytes. Eur J Biochem 271: 1671-1676.<br />

20. Kikonyogo A y Pietruszko R (1997). Cimetidine and other H-2-receptor antagonists as inhibitors of<br />

human E3 aldehyde dehydrogenase. Mol Pharmacol. 52: 267-271.<br />

220

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