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Dr Gnant - ESMO Oral Presentation 08

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Trial Status<br />

• 1,803 patients recruited from 1999 to 2006<br />

– Baseline demographics and disease characteristics well<br />

balanced between study arms<br />

• Median follow-up: 48 months<br />

• 137 first DFS events, 42 deaths recorded<br />

– 30 locoregional relapse events<br />

– 70 distant relapse events<br />

• 39 bone metastasis events<br />

– 16 contralateral breast cancer events<br />

– 19 new nonbreast primaries<br />

• Overall: 4-year DFS = 92.4%; 4-year OS = 97.7%<br />

8

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