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Dr Gnant - ESMO Oral Presentation 08

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Zoledronic Acid-Mediated Mechanisms<br />

Contributing to Improved Disease-Free Survival<br />

�Bone mets<br />

recurrence<br />

Direct<br />

antitumor<br />

activity<br />

�Non-bone<br />

mets recurrence<br />

�Contralateral<br />

recurrence<br />

�Disease-free survival<br />

Immune<br />

activation<br />

�Locoregional<br />

recurrence<br />

18

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