world cancer report - iarc
world cancer report - iarc
world cancer report - iarc
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depends on staging. Small intramucosal<br />
<strong>cancer</strong>s can be treated endoscopically by<br />
endoscopic mucosal resection [17]. For<br />
invasive <strong>cancer</strong>, standard treatment is<br />
gastrectomy with regional lymph node dissection<br />
[18]. For patients with advanced<br />
stage stomach <strong>cancer</strong>, neo-adjuvant (preoperative)<br />
or adjuvant (post-operative)<br />
chemotherapy is currently being investigated<br />
in research protocols. Drugs most<br />
often employed are 5-fluorouracil, doxorubicin<br />
and cisplatin, and greatest success<br />
has been achieved on the basis of combination<br />
regimens rather than single agent<br />
treatments. Immunochemosurgery using<br />
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incidence rate of gastric stump <strong>cancer</strong><br />
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surgery after <strong>cancer</strong> detection.<br />
In advanced stomach <strong>cancer</strong>, tumour<br />
stage, tumour size, histological tumour<br />
type, growth pattern, degree of cytological<br />
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reaction, lymphatic and vascular invasion<br />
all have prognostic value. Patients with<br />
<strong>cancer</strong>s limited to the mucosa and submucosa<br />
have a five-year survival of<br />
approximately 95%. Tumours that invade<br />
the muscularis propria have a 60% to 80%<br />
five-year survival, whereas tumours invading<br />
the subserosa and serosa have a less<br />
than 50% five-year survival on average<br />
[19]. There is recent evidence that the<br />
type of mucin and polymorphism of the<br />
gene encoding mucin may be an important<br />
factor determining susceptibility to<br />
stomach <strong>cancer</strong> [20].<br />
WEBSITE<br />
NCI Stomach (Gastric) Cancer Homepage:<br />
http://www.<strong>cancer</strong>.gov/<strong>cancer</strong>_information/<strong>cancer</strong>_type/<br />
stomach/<br />
Stomach <strong>cancer</strong><br />
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