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1/1 - eCommons@Cornell - Cornell University

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the basic building block of life, the<br />

DNA molecule. Biotechnology has<br />

created pigs that bleed human hemoglobin,<br />

bacteria that secrete cow hormones<br />

and roses with a natural blue<br />

tint. In the future, it could put summertime-fresh,<br />

vine-ripened tomatoes<br />

on supermarket shelves in February,<br />

make bacon with the fat content<br />

of chicken and cook up low-calorie<br />

french fries.<br />

Proponents call bioengineered<br />

foods the most important agricultural<br />

advance since the Green Revolution<br />

of the 1950s and '60s.<br />

Opponents call them Frankenfoods.<br />

<strong>Cornell</strong>, where some 400 faculty<br />

members work on bioengineering<br />

projects, is in the eye of the tempest<br />

because the possibility for practical<br />

use of the most widely-known (some<br />

would say notorious) recombinant<br />

product, bovine somatropin (bST),<br />

was first developed by animal science<br />

Prof. Dale E. Bauman. And it was<br />

horticulture Prof. John Sanford and<br />

engineering Professor Emeritus<br />

Edward Wolf who developed the<br />

"gene gun," a device that introduces<br />

foreign DNA into cells.<br />

But as in any debate, you can find<br />

<strong>Cornell</strong>ians on all sides of the<br />

bioengineered foods issue. The chief<br />

spokesman for the Washington, DCbased<br />

Union of Concerned Scientists<br />

(UCS) is Jane Rissler, PhD 77. The<br />

<strong>Cornell</strong>-affiliated Boyce Thompson<br />

Institute is home base for the National<br />

Agricultural Biotechnology<br />

Council, which tries to keep open the<br />

avenues of communication between<br />

those who support the science and<br />

those who fear it.<br />

The debate has even found its<br />

way into the classrooms of the Ag<br />

college, where most of the <strong>Cornell</strong>based<br />

bioengineering research is<br />

conducted. "A lot of students don't<br />

like it," says plant pathology Prof.<br />

Milton Zaitlin, associate director of<br />

the university's biotechnology program.<br />

"I tell them what my point of<br />

view is, and they still don't like it."<br />

Scientists believe that the fear of<br />

genetic engineering is simply a misunderstanding.<br />

Today's biotechnology,<br />

they say, is no more than a hightech<br />

spin on the ancient techniques<br />

of selective breeding, the process<br />

which brought us everything from<br />

sweet corn to Secretariat.<br />

"The beauty of the molecular<br />

route is that it allows you to move<br />

genes from any one organism to<br />

another, it allows you to move them<br />

in a very purified way," says Ralph<br />

W. F. Hardy, president and CEO of<br />

the 70-year-old Boyce Thompson<br />

Institute for Plant Research (BTI).<br />

"You're making a miniscule change<br />

in the kind of genetic material in the<br />

recipient organism, but you're giving<br />

it some capability—better nutrition,<br />

a longer shelf life, more tolerance<br />

to cold, better color, better flavor—than<br />

it had before. To me it<br />

doesn't matter if that gene came from<br />

a water buffalo, a fish or a bacteria."<br />

But it does matter to others.<br />

"I don't see that the<br />

technology will bring the<br />

benefits that many proponents<br />

think it will," says UCS's Jane<br />

Rissler. "To me the Flavr Savr tomato<br />

[a tomato genetically engineered<br />

to have a long shelf life] or a<br />

potato that has more solids in it so it<br />

takes up less oil when you fry it are<br />

not things that strike me as critical<br />

in the food supply. I would eat fewer<br />

french fries if I wanted to get less fat."<br />

Central to the debate is one biotechnology<br />

product in particular: a<br />

191 amino-acid protein hormone<br />

called bovine somatotropin (bST),<br />

also known as bovine growth hormone<br />

(BGH). The hormone, which<br />

occurs naturally in cows, helps the<br />

animals convert feed into milk.<br />

Supplemental injections of bST are<br />

designed to boost milk production.<br />

The product is marketed by its manufacturer,<br />

the chemical giant Monsanto,<br />

under the brand name Posilac,<br />

and was approved for general use by<br />

the U.S. Food and Drug Administra-<br />

CORNELL MAGAZINE<br />

24<br />

tion in November 1993, after more<br />

than 13 years of painstaking testing<br />

and investigation. Although Monsanto<br />

won't discuss how much it<br />

spent developing bST, chemical industry<br />

estimates of $300 million are<br />

common.<br />

Monsanto says that Posilac can<br />

increase milk production in a wellmanaged<br />

herd of dairy cows by 15<br />

percent per cow (some put the figure<br />

as high as 25 percent). Monsanto<br />

says bST is safe for humans, will be<br />

a boon to farmers and will improve<br />

the environment because dairies will<br />

be able to produce more milk with<br />

fewer cows, which in turn will produce<br />

less waste (an average dairy<br />

cow produces about 100 pounds of<br />

solid and liquid waste per day).<br />

Monsanto says that with bST, farmers<br />

can increase a cow's daily milk<br />

production by about nine pounds,<br />

giving the farmer an additional annual<br />

$8,000 profit for a 75-animal<br />

herd. The FDA estimates that 10 to<br />

15 percent of U.S. dairy farmers will<br />

be using bST by year's end.<br />

The hormone has been publicly<br />

endorsed by the American Medical<br />

Association, the National Institutes<br />

of Health and former Surgeon General<br />

of the United States C. Everett<br />

Koop, MD '41. Although the recombinant<br />

protein differs from the natural<br />

one by a single amino acid, authorities<br />

say that this does not affect<br />

the milk. They have declared milk<br />

from bST-treated cows to be identical<br />

to milk from untreated cows, and<br />

safe for human consumption.<br />

But despite official assurances,<br />

some consumers say they believe the<br />

product is healthy for neither cows<br />

nor people nor the environment nor<br />

the family farm. After all, scientists<br />

and the government told them silicone<br />

breast implants, DDT, DES and<br />

thalidomide were safe, too. The mass<br />

media has reflected the public fears<br />

about bioengineered foods with everything<br />

from segments on ABC's<br />

"20/20" to killer tomato cartoons in<br />

the New York Post<br />

Many in the scientific community

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