Air Quality Criteria for Lead Volume II of II - (NEPIS)(EPA) - US ...

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Air Quality Criteria for Lead (Second External Review Draft) VOLUME I EXECUTIVE SUMMARY .........................................................................................................E-1 1. INTRODUCTION ........................................................................................................... 1-1 2. CHEMISTRY, SOURCES, AND TRANSPORT OF LEAD.......................................... 2-1 3. ROUTES OF HUMAN EXPOSURE TO LEAD AND OBSERVED ENVIRONMENTAL CONCENTRATIONS.................................................................. 3-1 4. TOXICOKINETICS, BIOLOGICAL MARKERS, AND MODELS OF LEAD BURDEN IN HUMANS.................................................................................................. 4-1 5. TOXICOLOGICAL EFFECTS OF LEAD IN LABORATORY ANIMALS AND IN VITRO TEST SYSTEMS................................................................................. 5-1 6. EPIDEMIOLOGIC STUDIES OF HUMAN HEALTH EFFECTS ASSOCIATED WITH LEAD EXPOSURE .................................................................... 6-1 7. ENVIRONMENTAL EFFECTS OF LEAD ................................................................... 7-1 8. INTEGRATIVE SYNTHESIS OF LEAD EXPOSURE/HEALTH EFFECTS INFORMATION............................................................................................ 8-1 VOLUME II CHAPTER 4 ANNEX (TOXICOKINETICS, BIOLOGICAL MARKERS, AND MODELS OF LEAD BURDEN IN HUMANS) ............................................. AX4-1 CHAPTER 5 ANNEX (TOXICOLOGICAL EFFECTS OF LEAD IN LABORATORY ANIMALS AND IN VITRO TEST SYSTEMS) ................ AX5-1 CHAPTER 6 ANNEX (EPIDEMIOLOGIC STUDIES OF HUMAN HEALTH EFFECTS ASSOCIATED WITH LEAD EXPOSURE) ................................. AX6-1 CHAPTER 7 ANNEX (ENVIRONMENTAL EFFECTS OF LEAD).................................. AX7-1 II-vi
Table of Contents Page PREFACE .................................................................................................................................. II-iii DISCLAIMER ............................................................................................................................ II-v List of Tables .............................................................................................................................. II-x Authors, Contributors, and Reviewers..................................................................................... II-xxi U.S. Environmental Protection Agency Project Team for Development of Air Quality Criteria for Lead................................................................................................. II-xxvii U.S. Environmental Protection Agency Science Advisory Board (SAB) Staff Office Clean Air Scientific Advisory Committee (CASAC)........................................... II-xxix Abbreviations and Acronyms ................................................................................................ II-xxxi AX4. CHAPTER 4 ANNEX (TOXICOKINETICS, BIOLOGICAL MARKERS, AND MODELS OF LEAD BURDEN IN HUMANS) ................................... AX4-1 REFERENCES ...................................................................................................... AX4-44 II-vii
Page 1 and 2: October 2006 EPA/600/R-05/144bF Air
Page 3 and 4: PREFACE National Ambient Air Qualit
Page 5: NCEA acknowledges the valuable cont
Page 9 and 10: Authors, Contributors, and Reviewer
Page 11 and 12: Contributors and Reviewers (cont’
Page 13 and 14: Contributors and Reviewers (cont’
Page 15 and 16: Executive Direction U.S. Environmen
Page 17 and 18: Chair U.S. Environmental Protection
Page 19 and 20: Abbreviations and Acronyms αFGF α
Page 21 and 22: BLL blood lead level BLM biotic lig
Page 23 and 24: CRI chronic renal insufficiency CSF
Page 25 and 26: EPT macroinvertebrates from the Eph
Page 27 and 28: GRP78 glucose-regulated protein 78
Page 29 and 30: KABC Kaufman Assessment Battery for
Page 31 and 32: NADP nicotinamide adenine dinucleot
Page 33 and 34: Pb(Ac)2 lead acetate PbB blood lead
Page 35 and 36: RR RT RSEM RSUC RT ∑SEM SA7 SAB S
Page 37 and 38: TGF transforming growth factor TH t
Page 39 and 40: AX4. CHAPTER 4 ANNEX ANNEX TABLES A
Page 41 and 42: AX4-3 Table AX4-1 (cont’d). Analy
Page 43 and 44: AX4-5 Table AX4-2 (cont’d). Summa
Page 45 and 46: AX4-7 Table AX4-3. Bone Lead Measur
Page 47 and 48: AX4-9 Reference, Study Location, an
Page 49 and 50: AX4-11 Table AX4-4 (cont’d). Bone
Page 57 and 58:
AX4-19 Reference, Study Location, a
Page 59 and 60:
Page 61 and 62:
Page 63 and 64:
Page 65 and 66:
Page 67 and 68:
Page 69 and 70:
AX4-31 Table AX4-8 (cont’d). Bone
Page 71 and 72:
Page 73 and 74:
Page 75 and 76:
AX4-37 Table AX4-9 (cont’d). Lead
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AX4-39 Table AX4-11. Summary of Sel
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AX4-41 Table AX4-11 (cont’d). Sum
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AX-43 Table AX4-12 (cont’d). Summ
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Barltrop, D.; Meek, F. (1979) Effec
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Carroll, R. J.; Galindo, C. D. (199
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Flegal, A. R.; Smith, D. R. (1995)
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Gulson, B.; Mizon, K.; Smith, H.; E
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Khoury, G. A.; Diamond, G. L. (2003
Page 93 and 94:
Morgan, W. D.; Ryde, S. J.; Jones,
Page 95 and 96:
Pounds, J. G.; Leggett, R. W. (1998
Page 97 and 98:
Skerfving, S. (1988) Biological mon
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U.S. Environmental Protection Agenc
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Air Quality Criteria for Lead Volum
Page 103 and 104:
AQCD/Addendum and 1990 Supplement,
Page 105 and 106:
Air Quality Criteria for Lead (Seco
Page 107 and 108:
List of Tables AX4-1 Analytical Met
Page 109 and 110:
List of Tables (cont’d) AX5-6.3 G
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List of Tables (cont’d) AX5-9.3 S
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Principal Authors (cont’d) Author
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Principal Authors Authors, Contribu
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Principle Authors (cont’d) Author
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Technical Support Staff U.S. Enviro
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Members (cont’d) U.S. Environment
Page 123 and 124:
ANP atrial natriuretic peptide AP a
Page 125 and 126:
CCE Coordination Center for Effects
Page 127 and 128:
DR drinking water DSA delayed spati
Page 129 and 130:
FTII Fagan Test of Infant Intellige
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H3PO4 phosphoric acid HPRT hypoxant
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MATC maximum acceptable threshold c
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NOS nitric oxide synthase; not othe
Page 137 and 138:
PPVT-R Peabody Picture Vocabulary T
Page 139 and 140:
SOPR sperm-oocyte penetration rate
Page 141 and 142:
vit C vitamin C vit E vitamin E VMA
Page 143 and 144:
AX5-2 Table AX5-2.1. Effect of Lead
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AX5-4 Table AX5-2.1 (cont’d). Eff
Page 147 and 148:
AX5-6 Table AX5-2.2. Lead, Erythroc
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AX5-8 Table AX5-2.2 (cont’d). Lea
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AX5-10 Table AX5-2.4. Lead Effects
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AX5-12 Table AX5-2.5. Lead Interact
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AX5-14 Table AX5-2.7. Lead, Erythro
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AX5-16 Subject Exposure Protocol Ra
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AX5-22 Subject Rat, female, 22 wks
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AX5-24 Subject Rat, F344, male Expo
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AX5-26 Subject Monkey, cynomolgus,
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AX5-28 Subject Rat, SD, male, PND 6
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AX5-30 Subject Monkey, cynomolgus,
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AX5-32 Subject Exposure Protocol Ta
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AX5-34 Table AX5-3.6 (cont’d). Ke
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AX5-36 Table AX5-3.6 (cont’d). Ke
Page 179 and 180:
AX5-38 Citation Al-Hakkak et al. (1
Page 181 and 182:
AX5-40 Citation Fox et al. (1997)
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AX5-42 Citation Pinon- Lataillade e
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AX5-44 Citation Wiebe et al. (1998)
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AX5-46 Citation Chowdhuri et al. (2
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AX5-48 Citation Graca et al. (2004)
Page 191 and 192:
AX5-50 Citation Marchlewicz et al.
Page 193 and 194:
AX5-52 Table AX5-4.2 (cont’d). Ef
Page 195 and 196:
AX5-54 Citation Sokol et al. (1985)
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AX5-56 Citation Table AX5-4.3 (cont
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AX5-58 Citation Priya et al. (2004)
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ANNEX TABLES AX5-5 AX5-60
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AX5-62 Table AX5-5.1 (cont’d). In
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AX5-64 Table AX5-5.1 (cont’d). In
Page 207 and 208:
AX5-66 Reference Watts et al. (1995
Page 209 and 210:
AX5-68 Reference Lai et al. (2002)
Page 211 and 212:
AX5-70 Reference Shelkovnikov and G
Page 213 and 214:
AX5-72 Reference Fujiwara and Kaji
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AX5-74 Reference Fugiwara et al. (1
Page 217 and 218:
AX5-76 Table AX5-6.1. Genotoxic/Car
Page 219 and 220:
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AX5-80 Table AX5-6.3 (cont’d). Ge
Page 223 and 224:
Page 225 and 226:
Page 227 and 228:
AX5-86 Compound Table AX5-6.6. Geno
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Page 231 and 232:
Page 233 and 234:
Page 235 and 236:
Page 237 and 238:
AX5-96 Table AX5-6.10 (cont’d). G
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AX5-98 Table AX5-6.12. Genotoxic/Ca
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AX5-100 Table AX5-6.14. Genotoxic/C
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AX5-102 Compound Table AX5-6.16. Ge
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AX5-104 Table AX5-6.18. Genotoxic/C
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AX5-106 Table AX5-6.18 (cont’d).
Page 249 and 250:
Page 251 and 252:
AX5-110 Compound Assay (Concentrati
Page 253 and 254:
AX5-112 Table AX5-7.1. Light Micros
Page 255 and 256:
AX5-114 Table AX5-7.2. Lead and Fre
Page 257 and 258:
AX5-116 Table AX5-7.2 (cont’d). L
Page 259 and 260:
AX5-118 Table AX5-7.4. Effect of Ch
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AX5-120 Table AX5-7.5 (cont’d). E
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AX5-122 Table AX5-8.1. Bone Growth
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AX5-124 Table AX5-8.1 (cont’d). B
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AX5-126 Table AX5-8.2. Regulation o
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AX5-128 Table AX5-8.2 (cont’d). R
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AX5-136 Table AX5-8.4. Bone Lead as
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AX5-142 Table AX5-8.5. Uptake of Le
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AX5-144 Table AX5-8.7. Effects of L
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AX5-148 Nature of Exposure Table AX
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AX5-150 Table AX5-9.2. Effect of Le
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AX5-152 Species Strain/Gender Age M
Page 295 and 296:
Page 297 and 298:
Page 299 and 300:
Page 301 and 302:
Page 303 and 304:
AX5-162 Table AX5-10.2. Biochemical
Page 305 and 306:
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AX5-166 Table AX5-10.4. Lead, Oxida
Page 309 and 310:
Page 311 and 312:
Page 313 and 314:
Page 315 and 316:
Page 317 and 318:
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AX5-180 Table AX5-10.7. Lead and In
Page 323 and 324:
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AX5-184 Table AX5-10.9. Lead, Calci
Page 327 and 328:
Page 329 and 330:
AX5-188 Source Organ Species Table
Page 331 and 332:
REFERENCES Abdollahi, M.; Dehpour,
Page 333 and 334:
Bataineh, H.; Al-Hamood, M. H.; Elb
Page 335 and 336:
Buchet, J.-P.; Roels, H. E.; Huberm
Page 337 and 338:
Cline, H. T.; Witte, S.; Jones, K.
Page 339 and 340:
Cory-Slechta, D. A.; McCoy, L.; Ric
Page 341 and 342:
children's health: immune and respi
Page 343 and 344:
Ferguson, C.; Kern, M.; Audesirk, G
Page 345 and 346:
Fullmer, C. S. (1991) Intestinal ca
Page 347 and 348:
Goyer, R. A.; Leonard, D. L.; Moore
Page 349 and 350:
Hengstler, J. G.; Bolm-Audorff, U.;
Page 351 and 352:
Jacquet, P.; Leonard, A.; Gerber, G
Page 353 and 354:
Kim, K. A.; Chakraborti, T.; Goldst
Page 355 and 356:
Laughlin, N. K.; Bowman, R. E.; Fra
Page 357 and 358:
Maldonado-Vega, M.; Cerbón-Solórz
Page 359 and 360:
Moorman, W. J.; Skaggs, S. R.; Clar
Page 361 and 362:
O'Flaherty, E. J.; Inskip, M. J.; F
Page 363 and 364:
Price, R. G.; Taylor, S. A.; Chiver
Page 365 and 366:
Rodamilans, M.; Mtz.-Osaba, M. J.;
Page 367 and 368:
Schlipkoter, H.-W.; Frieler, L. (19
Page 369 and 370:
Skoczyńska, A.; Smolik, R.; Jeleń
Page 371 and 372:
Tavakoli-Nezhad, M.; Pitts, D. K. (
Page 373 and 374:
Valentino, M.; Governa, M.; Marchis
Page 375 and 376:
Wetmur, J. G.; Lehnert, G.; Desnick
Page 377 and 378:
Zhou, J.; Xu, Y.-H.; Chang, H.-F. (
Page 379 and 380:
Air Quality Criteria for Lead Volum
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The purpose of this revised Lead AQ
Page 383 and 384:
Air Quality Criteria for Lead (Seco
Page 385 and 386:
List of Tables Number Page AX6-2.1
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List of Tables (cont’d) Number Pa
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Page 393 and 394:
Page 395 and 396:
Page 397 and 398:
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ANOVA analysis of variance ANP atri
Page 401 and 402:
CCD charge-coupled device CCE Coord
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DPPD N-N-diphenyl-p-phynylene-diami
Page 405 and 406:
FTES free testosterone FTII Fagan T
Page 407 and 408:
HPLC high-pressure liquid chromatog
Page 409 and 410:
MAO monoamine oxidase MATC maximum
Page 411 and 412:
NORs nucleolar organizing regions N
Page 413 and 414:
ppm parts per million PPVT-R Peabod
Page 415 and 416:
Page 417 and 418:
Page 419 and 420:
Page 421 and 422:
AX6-4 Table AX6-2.1 (cont’d). Pro
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Page 425 and 426:
Page 427 and 428:
AX6-10 Table AX6-2.2 (cont’d). Me
Page 429 and 430:
AX6-12 Table AX6-2.3 (cont’d). Cr
Page 431 and 432:
AX6-14 Table AX6-2.4. Effects of Le
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Page 435 and 436:
Page 437 and 438:
Page 439 and 440:
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AX6-24 Table AX6-2.8. Effects of Le
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Page 445 and 446:
Page 447 and 448:
AX6-30 Table AX6-3.1. Neurobehavior
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AX6-32 Table AX6-3.1 (cont’d). Ne
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AX6-34 Table AX6-3.2 (cont’d). Sy
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AX6-36 Table AX6-3.3. Neurobehavior
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Page 465 and 466:
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AX6-50 Table AX6-3.4 (cont’d). Me
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AX6-56 Table AX6-3.6. Evoked Potent
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AX6-58 Table AX6-3.6 (cont’d). Ev
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AX6-60 Table AX6-3.7 (cont’d). Po
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AX6-62 Table AX6-3.7 (cont’d). Po
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AX6-64 Table AX6-3.8 (cont’d). Oc
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AX6-66 Table AX6-3.9. Other Neurolo
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AX6-68 Table AX6-3.9 (cont’d). Ot
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AX6-70 Table AX6-4.1. Renal Effects
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AX6-72 Table AX6-4.1 (cont’d). Re
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AX6-104 Table AX6-4.3. Renal Effect
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AX6-166 Table AX6-5.4. Cardiovascul
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AX6-170 Table AX6-6.1 (cont’d). P
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AX172 Table AX6-6.1 (cont’d). Pla
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AX6-174 Table AX6-6.2. Lead Exposur
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AX6-176 Table AX6-6.2 (cont’d). L
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Page 603 and 604:
AX6-186 Table AX6-7.2. Key Occupati
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AX6-188 Table AX6-7.2 (cont’d). K
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AX6-190 Table AX6-7.2 (cont’d). K
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AX6-192 Table AX6-7.3. Key Studies
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AX6-194 Table AX6-7.4. Other Studie
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AX6-196 Table AX6-7.4 (cont’d). O
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AX6-224 Table 6-9.2 (cont’d). Eff
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AX6-232 Table AX6-9.3 (cont’d.).
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AX6-258 Table AX6-9.10. Effects of
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REFERENCES Abbate, C.; Buceti, R.;
Page 679 and 680:
Baghurst, P. A.; McMichael, A. J.;
Page 681 and 682:
Bolla, K. I.; Schwartz, B. S.; Stew
Page 683 and 684:
Chia, K. S.; Jeyaratnam, J.; Tan, C
Page 685 and 686:
David, O. J.; Clark, J.; Hoffman, S
Page 687 and 688:
Englyst, V.; Lundstrom, N. G.; Gerh
Page 689 and 690:
Gennart, J. P.; Bernard, A.; Lauwer
Page 691 and 692:
Haraguchi, T.; Ishizu, H.; Takehisa
Page 693 and 694:
Jemal, A.; Graubard, B. I.; Devesa,
Page 695 and 696:
Lanphear, B. P.; Howard, C.; Eberly
Page 697 and 698:
Lundström, N.-G.; Nordberg, G.; En
Page 699 and 700:
Muntner, P.; He, J.; Vupputuri, S.;
Page 701 and 702:
Paksy, K.; Gáti, I.; Náray, M.; R
Page 703 and 704:
Rhainds, M.; Levallois, P.; Dewaill
Page 705 and 706:
Sargent, J. D.; Dalton, M. A.; O'Co
Page 707 and 708:
Sheffet, A.; Thind, I.; Miller, A.
Page 709 and 710:
Stevens, L. A.; Levey, A. S. (2005b
Page 711 and 712:
Van Larebeke, N.; Koppen, G.; Nelen
Page 713 and 714:
Winker, R.; Ponocny-Seliger, E.; R
Page 715 and 716:
October 2006 EPA/600/R-05/144bF Air
Page 717 and 718:
PREFACE National Ambient Air Qualit
Page 719 and 720:
drafts of document materials were r
Page 721 and 722:
Table of Contents PREFACE..........
Page 723 and 724:
Table of Contents (cont’d) II-ix
Page 725 and 726:
List of Tables (cont’d) AX7-2.3.1
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List of Figures (cont’d) Number P
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Page 731 and 732:
Page 733 and 734:
Page 735 and 736:
Page 737 and 738:
Page 739 and 740:
ANOVA analysis of variance ANP atri
Page 741 and 742:
CCD charge-coupled device CCE Coord
Page 743 and 744:
DPPD N-N-diphenyl-p-phynylene-diami
Page 745 and 746:
FTES free testosterone FTII Fagan T
Page 747 and 748:
HPLC high-pressure liquid chromatog
Page 749 and 750:
MAO monoamine oxidase MATC maximum
Page 751 and 752:
NORs nucleolar organizing regions N
Page 753 and 754:
ppm parts per million PPVT-R Peabod
Page 755 and 756:
Page 757 and 758:
Page 759 and 760:
Pb is ideally suited for this task.
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Concept For a given metal or metall
Page 763 and 764:
(1979) observed that “the smaller
Page 765 and 766:
Figure AX7-1.1.3. Illustration of p
Page 767 and 768:
• Colorimetric • Electrochemica
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Figure AX7-1.1.5. Bulk lead versus
Page 771 and 772:
diffraction lines and comparing the
Page 773 and 774:
The major disadvantage of SIMS to s
Page 775 and 776:
techniques can be useful in a study
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have included phosphoric acid (H3PO
Page 779 and 780:
to 15 years after biosolid applicat
Page 781 and 782:
thin films (DGT), and ICP technique
Page 783 and 784:
completely extract targeted phases.
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epresents Eb. The precise energy re
Page 787 and 788:
1974; Ruby et al., 1994). However,
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T1/2 = 14 × 10 9 year). The result
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floor) time-series data to evaluate
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contributions of dry deposition may
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Compared to their estimated 20th-ce
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thought to enter the plant via the
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soil was not allowed to equilibrate
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Lead concentrations in various tiss
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that the nematode may detoxify Pb v
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plasma levels of uric acid and crea
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effective use of glutathione metabo
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and oats (Avena sativa) had signifi
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other metals is inconsistent (Påhl
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Speciation and Form of Lead Recent
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organism responses to Pb. Section A
Page 817 and 818:
Primary Producers Commonly reported
Page 819 and 820:
solution and minimal translocation
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AX7.1.3.3 Recent Studies on the Eff
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AX7-66 Avian Species Reproduction J
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AX7-68 Avian Species American kestr
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Very little research has been done
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AX7-72 Mammalian Species Reproducti
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AX7-74 Mammalian Species No. of Dos
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Page 835 and 836:
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AX7-80 Mammalia n Species No. of Do
Page 839 and 840:
A literature search and review was
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Table AX7-1.3.6. Invertebrate Toxic
Page 843 and 844:
The effects of Pb-chloride on the p
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Ecological Soil Screening Levels (E
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Since the movement and fate of Pb i
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Land Use and Industry Changes in la
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lakes in the United Kingdom the dis
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zinc; had very low pH; and were det
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Sites Affected by Long-Range Lead T
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iomass carbon. Because of this link
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in an oak woodland site 3 km from a
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the forested Lehstenbach catchment
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there is little evidence that Pb ac
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ecosystems. Just as in the terrestr
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To develop chronic AWQC, acceptable
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for the binding of free-metal ion a
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partition in sediment between acid-
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AX7.2.1.5 Metal Mixtures As discuss
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varies from 4:1 in rural streams to
Page 877 and 878:
Organic compounds in surface waters
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solution phase, complexation with c
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The NAWQA dataset was chosen over o
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Lead Distributions Generated from t
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AX7-128 Figure AX7-2.2.3. Spatial d
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AX7-130 Figure AX7-2.2.5. Spatial d
Page 889 and 890:
AX7-132 ` Figure AX7-2.2.7. Spatial
Page 891 and 892:
Figure AX7-2.2.8. Frequency distrib
Page 893 and 894:
Table AX7-2.2.4. Summary Statistics
Page 895 and 896:
Table AX7-2.2.5. Comparison of NCBP
Page 897 and 898:
AX7-140 Figure AX7-2.2.13. Spatial
Page 899 and 900:
calculations indicate that only a s
Page 901 and 902:
from municipal sewage, storm runoff
Page 903 and 904:
AX7.2.3 Aquatic Species Response/Mo
Page 905 and 906:
aquatic plants and insects and on t
Page 907 and 908:
designed to model uptake, MINTEQ pr
Page 909 and 910:
sequestering to organ tissues). The
Page 911 and 912:
AbdAllah and Moustafa (2002) studie
Page 913 and 914:
Summary of Detoxifiction Processes
Page 915 and 916:
1.1 µg/L Cd, 12 µg/L Cu, 55 µg/L
Page 917 and 918:
Studies have identified ALAD in fis
Page 919 and 920:
metals over nonessential metals. Th
Page 921 and 922:
In summary, relationships between a
Page 923 and 924:
potential toxic effects in other or
Page 925 and 926:
esulted in 91.7% survival (Horne an
Page 927 and 928:
carbon sources (including glucose),
Page 929 and 930:
separate concentration-effects mode
Page 931 and 932:
1994. mSQGQs are useful to risk ass
Page 933 and 934:
Algae The 1986 Lead AQCD (U.S. Envi
Page 935 and 936:
observed in Selenastrum capricornut
Page 937 and 938:
Nitrate uptake reported after 48, 7
Page 939 and 940:
1997). The most sensitive primary p
Page 941 and 942:
Freshwater Invertebrates Acute and
Page 943 and 944:
AX7-186 Amphipod (Hyalella azteca)
Page 945 and 946:
concentrations of
Page 947 and 948:
AX7-190 Freshwater Species Chemical
Page 949 and 950:
AX7-192 Species Chemical Frogs (Ran
Page 951 and 952:
studied using Spirodela polyrhiza,
Page 953 and 954:
However, in other cases multivariat
Page 955 and 956:
species was observed. Similar, sign
Page 957 and 958:
AX7-200 Table AX7-2.5.2. Essential
Page 959 and 960:
AX7-202 Table AX7-2.5.2 (cont’d).
Page 961 and 962:
variables, it does not imply causat
Page 963 and 964:
Poulton et al. (1995), the effects
Page 965 and 966:
metal levels. Furthermore, although
Page 967 and 968:
environment through bioaccumulation
Page 969 and 970:
Angle, C. R.; McIntire, M. S.; Colu
Page 971 and 972:
Black, M. C.; Ferrell, J. R.; Horni
Page 973 and 974:
Clements, W. H. (1994) Benthic inve
Page 975 and 976:
Ekenler, M.; Tabatabai, M. (2002) E
Page 977 and 978:
Getz, L. L.; Haney, A. W.; Larimore
Page 979 and 980:
Houlton, B. Z.; Driscoll, C. T.; Fa
Page 981 and 982:
Krüger, F.; Gröngröft, A. (2003)
Page 983 and 984:
Manceau, A.; Lanson, B.; Schlegel,
Page 985 and 986:
Niyogi, S.; Wood, C. M. (2003) Effe
Page 987 and 988:
Rand, G. M.; Wells, P. G.; McCarty,
Page 989 and 990:
Scherer, E.; McNicol, R. E. (1998)
Page 991 and 992:
Sturges, W. T.; Barrie, L. A. (1987
Page 993 and 994:
U.S. Environmental Protection Agenc
Page 995 and 996:
Zenk, M. H. (1996) Heavy metal deto
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