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Environmental Health Criteria 214

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HUMAN EXPOSURE ASSESSMENT<br />

Using a deterministic model for a given contaminant, exposure<br />

concentration is estimated as a concentration averaged over a given<br />

period of time (see Eq. 3.1, p. 46).<br />

For the inhalation and dermal exposure routes, concentrations in<br />

the different microenvironments occupied by a person are integrated<br />

over time. The integrated time period is usually 24 h, 1 year or a<br />

lifetime of 70 years, although any time period may be used. The<br />

concept of microenvironment is often unnecessary for the ingestion<br />

route. In this case, the concentration of contaminants in the food<br />

consumed and the amount of food and beverages consumed during a given<br />

period of time are sufficient to determine exposure.<br />

6.3 <strong>Environmental</strong> media and exposure media<br />

In exposure analysis, we use human exposure assessments to<br />

translate contaminant levels in environmental media into quantitative<br />

estimates of the amount of contaminant that comes in contact with the<br />

human-environment boundaries, that is, the lungs, the gastrointestinal<br />

tract and the skin surface of individuals within a specified<br />

population. <strong>Environmental</strong> media of principal relevance to human<br />

exposure include air, ground-surface soil, root-zone soil, plants,<br />

groundwater and surface water in the contaminated landscape. As<br />

described in Chapter 2, exposure pathways define a link between an<br />

environmental medium and an exposure medium. Important exposure media<br />

include outdoor air, indoor air, food (commercial and homegrown),<br />

exterior soil, interior soil or household dust, and drinking and<br />

cooking water. Exposure then occurs by contact with contaminants in<br />

http://www.inchem.org/documents/ehc/ehc/ehc<strong>214</strong>.htm<br />

Page 95 of 284<br />

6/1/2007

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