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Environmental Health Criteria 214

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HUMAN EXPOSURE ASSESSMENT<br />

Standardized methods are not available for collecting information<br />

on hand-mouth contact. Several researchers (Charney et al., 1980;<br />

Brunekreef et al., 1983; Bellinger et al., 1986) have administered<br />

questionnaires to parents of toddler-age participants in order to<br />

qualitatively characterize the frequency with which children suck<br />

their fingers (i.e., usually, sometimes, never). Direct observation<br />

may be better suited to capturing micro-level activities, but such<br />

approaches have rarely been used in large-scale field studies owing to<br />

the expense of following more than a few participants and because of<br />

concerns that the observation process will lead to bias or alterations<br />

in typical patterns. Video techniques have now made it possible to<br />

record participant activities with less interference. Davies et al.<br />

(1990), for instance, used video methods to obtain data on the number<br />

of times 2 year olds put their hands and objects in their mouth while<br />

in standardized play situations. Zartarian et al. (1995) used<br />

videotape data to collect micro-level data on four young farm children<br />

at play inside their homes to quantify dermal and ingestion exposure<br />

to pesticides. As Zartarian et al. point out, however, researcher<br />

presence may still have influenced the participants' behaviour.<br />

Observation of children's hand-mouth contact also has been performed<br />

in clinical settings (e.g., Madden et al., 1980). All of these<br />

methods, however, share the limitation that they cannot quantify the<br />

full variability in factors that influence hand-mouth contact. Indeed,<br />

capturing this variability may not even be possible, as is discussed<br />

in a subsequent section of this chapter. In the absence of information<br />

on hand-mouth contact, several researchers have measured mineral<br />

levels in children's faeces to estimate typical soil ingestion rates<br />

(Binder et al., 1986; Calabrese et al., 1989, 1990). Such estimated<br />

ingestion rates can then be used to model exposure in areas with<br />

measured soil contamination levels.<br />

For dermal exposure, questionnaires are most appropriate for<br />

collecting categorical-type information, such as whether a person<br />

performed a certain activity during a designated activity. The US<br />

http://www.inchem.org/documents/ehc/ehc/ehc<strong>214</strong>.htm<br />

Page 88 of 284<br />

6/1/2007

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