Environmental Health Criteria 214
Environmental Health Criteria 214
Environmental Health Criteria 214
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HUMAN EXPOSURE ASSESSMENT<br />
30 µg/dl. The study also found a significant correlation between high<br />
blood lead levels and proximity of the household to dense traffic. In<br />
a 1990-1991 study of exposure to lead among schoolchildren in Manila,<br />
Subida & Torres (1991) found that mean blood lead concentrations were<br />
14 µg/dl ( n = 387), with 10% having levels over 10 µg/dl. The same<br />
study measured blood lead levels among child street vendors. Mean<br />
blood lead level for a sample of 101 vendors was 17.8 µg/dl, with 33%<br />
having levels over 20 µg/dl.<br />
Muangnoicharon (WHO, 1995b) reports on a lead exposure study of<br />
bus drivers in Bangkok. The study was a cooperation between the WHO<br />
HEAL Project and the Department of Medical Science, Ministry of Public<br />
<strong>Health</strong> of Thailand and was designed to assess exposure in a high risk<br />
group. Subjects were bus drivers assigned to traffic routes in Bangkok<br />
where ambient lead levels exceeded 1 µg/m 3 . Lead was analysed in 24-h<br />
air samples, duplicate food for each meal for 6 days and faeces for 5<br />
days, as well as blood collected on the day 7.<br />
Average personal air exposures were 0.117 µg/m 3 , which yielded<br />
an estimated 0.936 µg/day absorption by inhalation at an estimated<br />
absorption rate of lead via inhalation of 40% and 20 m 3 /day<br />
respiratory air. Intake by food was 87.92 µg/day (27.32 SD). Thus, the<br />
estimated average lead absorption from air, food and water was 13.325<br />
µg/day at an estimated absorption rate via ingestion of 10%.<br />
Researchers suggested that meals consumed from roadside restaurants<br />
and food stands resulted in higher than expected lead levels in food.<br />
Blood lead levels for bus drivers ranged between 5 and 12 µg/dl.<br />
The results for the Thai study were compared to other HEAL<br />
sponsored studies in China, Sweden and Yugoslavia (Table 41).<br />
One of the HEAL projects investigated lead and cadmium exposure<br />
among small groups of non-smoking women (Vahter & Slorach, 1990).<br />
Subjects kept activity diaries. Duplicate portions of food and<br />
corresponding faeces samples were collected along with personal air<br />
samples. Food was found to be the main source of both lead and<br />
cadmium. Faecal concentrations could be used for validation of the<br />
duplicate portion samples because of the low uptake in the<br />
Page 221 of 284<br />
Table 40. Weighted estimates of air and breath concentrations of 19 prevale<br />
residents (February 1984); 330 000 Los Angeles residents (May 1984);<br />
(June 1984)<br />
Compound LA1 (February) LA2 (May)<br />
Personal Outdoor Breath Personal Outdoor B<br />
air air air air<br />
(n = 110) (24) (110) (50) (23) (<br />
1,1,1-Trichloroethane 96 a 34 a 39 b 44 5.9 23<br />
m,p-Xylene 28 24 3.5 24 9.4 2<br />
m,p-Dichlorobenzene 18 2.2 5.0 12 0.8 2<br />
Benzene 18 16 8.0 9.2 3.6 8<br />
Tetrachloroethylene 16 10 12 15 2.0 9<br />
o-Xylene 13 11 1.0 7.2 2.7 0<br />
Ethylbenxene 11 9.7 1.5 7.4 3.0 1<br />
Trichloroethylene 7.8 0.8 1.5 6.4 0.1 1<br />
http://www.inchem.org/documents/ehc/ehc/ehc<strong>214</strong>.htm<br />
6/1/2007