New Modes of GPCR Signalling
New Modes of GPCR Signalling
New Modes of GPCR Signalling
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INVITED SPEAKER’S INFO<br />
Pr<strong>of</strong>. Jianzhi Wang<br />
PhD, Pr<strong>of</strong>essor, Director,<br />
Pr<strong>of</strong>essor and Director <strong>of</strong> Pathophysiology<br />
Pathophysiology Department,<br />
Tongji Medical College,<br />
Huazhong University <strong>of</strong> Science and Technology<br />
Wuhan, Hubei Province, 430074 P.R.China<br />
Email: wangjz@mails.tjmu.edu.cn<br />
Education and Training<br />
1975-1978 General Medicine,<br />
Tongji (Wuhan) Medical College, Wuhan, China<br />
1985-1988 Post Graduate Training in Biochemistry,<br />
Tongji Medical University, Wuhan, China<br />
1992-1993 Postdoctoral Research in Biochemistry, Siena University, Siena, Italy<br />
1993-1996 Postdoctoral Research in Alzheimer disease,<br />
NYS Institute for Basic Research, SI, NY, USA<br />
Selected Publications<br />
1. Zhu LQ, Zheng HY, Peng CX, Liu D, Li HL, Wang Q and Wang JZ*. Protein<br />
Phosphatase 2A Facilitates Axonogenesis by Dephosphorylating CRMP2. J<br />
Neurosci. 30(10):3839 –48, 2010<br />
2. Zhu LQ, Liu D, Hu J, Cheng J, Wang SH, Wang Q, Wang F, Chen JG, and Wang<br />
JZ*. GSK-3 inhibits presynaptic<br />
vesicle exocytosis by phosphorylating P/Q-type<br />
calcium channel and interrupting SNARE complex formation. J Neurosci.<br />
30(10):3849 –55, 2010<br />
3. Wang JZ*, Liu F. Microtubule-associated protein tau in development, degeneration<br />
and protection <strong>of</strong> neurons. Prog Neurobiol. 85:148-75, 2008 An invited review<br />
4. Li HL, Wang HH, Liu SJ, Deng YQ, Zhang YJ, Tian Q, Wang XC, Chen XQ,<br />
Yang Y, Zhang JY, Wang Q, Xu H, Liao F and Wang JZ*. Phosphorylation <strong>of</strong> tau<br />
antagonizes apoptosis by stabilizing -catenin, a mechanism involved in<br />
Alzheimer’s neurodegeneration. Proc Natl Acad Sci U S A. 104(9): 3591-3596,<br />
2007<br />
5. Zhu LQ, Wang SH, Yin YY, Liu D, Zheng HY, Shi HR, Tian Q, Wang XC, Wang<br />
Q, Guo L, Wang JZ*. Activation <strong>of</strong> glycogen synthase kinase-3 inhibits long term<br />
potentiation with synapse-associated impairments. J Neurosci. 27,12211–20, 2007<br />
6. Wang D, Qian L, Xiong H, Liu J, Neckameyer WS, Oldham S, Xia K, Wang J,<br />
Bodmer R, Zhang Z.Antioxidants protect PINK1-dependent dopaminergic neurons<br />
in Drosophila. Proc Natl Acad Sci U S A. 103:13520-5,2006<br />
7. Liu SJ, Zhang JY, Li HJ, Fang ZY, Wang Q, Deng HM, Gong C, Iqbal K, Wang<br />
JZ*. Tau becomes a more favorable substrate for GSK-3 when it is
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