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New Modes of GPCR Signalling

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Activity-based Probe for Specific Photo-affinity Labelling <strong>of</strong> GABAB Receptors in<br />

Living Cells: Design, Synthesis and Biological Evaluation. J. Med. Chem<br />

12;51(11):3057-60.<br />

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cystein-rich domains during metabotropic glutamate receptors activation. Manuscrit<br />

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6. Tu HJ, Rondard P, Xu CJ, Bertaso F, Cao FN, Zhang XY, Pin JP, Liu JF. (2007)<br />

GABAB2 subunit and Gßγ are necessary for GABAB receptor mediated-ERK1/2<br />

phosphorylation in cerebellar granule neurons. Cell. Signal., 19(9):1996-2002.<br />

7. Zhang YL, Zhang HQ, Hua SN, Ma LH, Chen C, Liu XY, Jiang LQ, Yang HM,<br />

Zhang PC, Yu DQ, Guo YL, Tan XH, Liu JF. (2007) Identify two herbal<br />

compounds with potential cholesterol-lowing activity. Biochem. Pharmaco.,<br />

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Coupling <strong>of</strong> agonist binding to effector domain activation in metabotropic<br />

glutamate-like receptors. J. Biol. Chem., 281(34):24653-61. (co-first and<br />

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Allosteric functioning <strong>of</strong> dimeric class C G-protein-coupled receptors. FEBS<br />

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receptor 5 functions like rhodopsin-like receptors. Proc. Natl. Acad. Sci., 101(1):<br />

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12. Liu JF, Crepin M, Liu JM, Barritault D, Ledoux D. (2002) FGF-2 and TPA induce<br />

matrix metalloproteinase-9 secretion in MCF-7 cells through PKC activation <strong>of</strong> the<br />

Ras/ERK pathway. Biochem. Biophys. Res. Com., 293: 1174-1182.<br />

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Functional Rac-1 and Nck signaling networks are required for FGF-2-induced DNA<br />

synthesis in MCF-7 cells. Oncogene., 18: 6425-6433.<br />

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Bertin B. (1998) Fibroblast growth factor-2 has opposite effects on human breast<br />

cancer MCF-7 cell growth depending on the activation level <strong>of</strong> the<br />

mitogen-activated protein kinase pathway. Eur. J. Biochem., 258: 271-276.<br />

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