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Tungíase: doença negligenciada causando patologia grave

Tungíase: doença negligenciada causando patologia grave

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Table 3. Population attributable fractions of modifiable<br />

factors associated with tungiasis.<br />

Floor of sand or clay inside the<br />

house<br />

Common resting place outside<br />

house<br />

without elevated costs. For example, cementing the floors of those<br />

houses with sandy or clay floor in the community would reduce<br />

prevalence of tungiasis by almost 75%. In addition, this measure<br />

will reduce transmission on the long run without any additional<br />

costs for the next years. Similar, confining pigs to pigpens and<br />

explaining to community members the location of breeding sites<br />

and areas of high transmission would reduce considerably the<br />

prevalence in the community. As a spin-off, the discussed measures<br />

References<br />

Attributable<br />

risk<br />

% exposed<br />

among cases PAF<br />

0,89 82.5 73.7<br />

0,86 76.2 65.5<br />

Regular use of footwear 0,66 77.4 51.1<br />

Presence of pigs on compound 0,94 40.1 37.9<br />

doi:10.1371/journal.pntd.0000087.t003<br />

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probably reduce also the transmission of other parasitic diseases,<br />

such as neurocysticercosis, ancylostomiasis and strongyloidiasis.<br />

In conclusion, the presence of tungiasis in the community is<br />

associated to an important extent with a set of a few modifiable<br />

variables. Effective and sustainable intervention measures addressing<br />

these factors need to be implemented in the study area, and in<br />

other communities throughout West Africa, to reduce the burden<br />

of this neglected tropical disease. An integrated approach<br />

combining the control of animal reservoirs, housing and<br />

environmental factors, and health education is necessary. Intervention<br />

measures need to be designed by an interdisciplinary<br />

team together with the affected communities.<br />

Acknowledgments<br />

We thank the Baales and Ajido Erekiti communities for supporting the<br />

study and Mr. Durotimi Ashade and Mr. Ola Avhose for skillful assistance.<br />

LA received a PhD scholarship from Coordenação de Aperfeiçoamento de Pessoal<br />

de Nível Superior–CAPES (Brazil).<br />

Author Contributions<br />

Tungiasis in Nigeria<br />

Conceived and designed the experiments: JH UU IEO. Performed the<br />

experiments: UU. Analyzed the data: JH UU LA. Contributed reagents/<br />

materials/analysis tools: JH. Wrote the paper: JH UU IEO LA.<br />

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Parasitol Res 90: 87–99.<br />

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reservoir of Tunga penetrans in severely affected communities of north-east Brazil.<br />

Med Vet Entomol 18: 329–335.<br />

28. Muehlen M, Heukelbach J, Wilcke T, Winter B, Mehlhorn H, Feldmeier H<br />

(2003) Investigations on the biology, epidemiology, pathology and control of<br />

Tunga penetrans in Brazil II. Prevalence, parasite load and topographic<br />

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PLoS Neglected Tropical Diseases | www.plosntds.org 7 2007 | Volume 1 | Issue 3 | e87

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