Immunotherapy for Infectious Diseases

Immunotherapy for Infectious Diseases Immunotherapy for Infectious Diseases

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Active Immunization for HIV Infection 197 123. Tubiana R, Gomard E, Fleury H, et al. Vaccine therapy in early HIV-1 infection using a recombinant canarypox virus expressing gp160MN (ALVAC-HIV): a double-blind controlled randomized study of safety and immunogenicity [letter]. AIDS 1997; 11:819. 124. Dhodapkar MV, Krasovsky J, Steinman RM, Bhardwaj N. Mature dendritic cells boost functionally superior CD8(�) T-cell in humans without foreign helper epitopes. J Clin Invest 2000; 105:R9. 125. Dhodapkar MV, Steinman RM, Sapp M, et al. Rapid generation of broad T-cell immunity in humans after a single injection of mature dendritic cells. J Clin Invest 1999; 104:173. 126. Dhodapkar MV, Steinman RM, Krasovsky J, Munz C, Bhardwaj N. Antigen-specific inhibition of effector T cell function in humans after injection of immature dendritic cells. J Exp Med 2001; 193:233. 127. Engelmayer J, Larsson M, Lee A, et al. Mature dendritic cells infected with canarypox virus elicit strong anti-human immunodeficiency virus CD8� and CD4� T-cell responses from chronically infected individuals. J Virol 2001; 75:2142. 128. Caley IJ, Betts MR, Irlbeck DM, et al. Humoral, mucosal, and cellular immunity in response to a human immunodeficiency virus type 1 immunogen expressed by a Venezuelan equine encephalitis virus vaccine vector. J Virol 1997; 71:3031. 129. Davis NL, Caley IJ, Brown KW, et al. Vaccination of macaques against pathogenic simian immunodeficiency virus with Venezuelan equine encephalitis virus replicon particles. [erratum appears in J Virol 2000;74:3430]. J Virol 2000; 74:371. 130. Egan MA, Charini WA, Kuroda MJ, et al. Simian immunodeficiency virus (SIV) gag DNA-vaccinated rhesus monkeys develop secondary cytotoxic T-lymphocyte responses and control viral replication after pathogenic SIV infection. J Virol 2000; 74:7485. 131. Lu S, Arthos J, Montefiori DC, et al. Simian immunodeficiency virus DNA vaccine trial in macaques. J Virol 1996; 70:3978. 132. Barouch DH, Santra S, Schmitz JE, et al. Control of viremia and prevention of clinical AIDS in rhesus monkeys by cytokine-augmented DNA vaccination. Science 2000; 290:486. 133. Amara RR, Villinger F, Altman JD, et al. Control of a mucosal challenge and prevention of AIDS by a multiprotein DNA/MVA vaccine. Science 2001; 292:69. 134. Buge SL, Murty L, Arora K, et al. Factors associated with slow disease progression in macaques immunized with an adenovirus-simian immunodeficiency virus (SIV) envelope priming-gp120 boosting regimen and challenged vaginally with SIVmac251. J Virol 1999; 73:7430. 135. Allen TM, O’Connor DH, Jing P, et al. Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia. Nature 2000; 407:386.

Active Immunization <strong>for</strong> HIV Infection 197<br />

123. Tubiana R, Gomard E, Fleury H, et al. Vaccine therapy in early HIV-1 infection using a<br />

recombinant canarypox virus expressing gp160MN (ALVAC-HIV): a double-blind controlled<br />

randomized study of safety and immunogenicity [letter]. AIDS 1997; 11:819.<br />

124. Dhodapkar MV, Krasovsky J, Steinman RM, Bhardwaj N. Mature dendritic cells boost<br />

functionally superior CD8(�) T-cell in humans without <strong>for</strong>eign helper epitopes. J Clin<br />

Invest 2000; 105:R9.<br />

125. Dhodapkar MV, Steinman RM, Sapp M, et al. Rapid generation of broad T-cell immunity<br />

in humans after a single injection of mature dendritic cells. J Clin Invest 1999; 104:173.<br />

126. Dhodapkar MV, Steinman RM, Krasovsky J, Munz C, Bhardwaj N. Antigen-specific inhibition<br />

of effector T cell function in humans after injection of immature dendritic cells.<br />

J Exp Med 2001; 193:233.<br />

127. Engelmayer J, Larsson M, Lee A, et al. Mature dendritic cells infected with canarypox<br />

virus elicit strong anti-human immunodeficiency virus CD8� and CD4� T-cell responses<br />

from chronically infected individuals. J Virol 2001; 75:2142.<br />

128. Caley IJ, Betts MR, Irlbeck DM, et al. Humoral, mucosal, and cellular immunity in<br />

response to a human immunodeficiency virus type 1 immunogen expressed by a Venezuelan<br />

equine encephalitis virus vaccine vector. J Virol 1997; 71:3031.<br />

129. Davis NL, Caley IJ, Brown KW, et al. Vaccination of macaques against pathogenic simian<br />

immunodeficiency virus with Venezuelan equine encephalitis virus replicon particles.<br />

[erratum appears in J Virol 2000;74:3430]. J Virol 2000; 74:371.<br />

130. Egan MA, Charini WA, Kuroda MJ, et al. Simian immunodeficiency virus (SIV) gag<br />

DNA-vaccinated rhesus monkeys develop secondary cytotoxic T-lymphocyte responses<br />

and control viral replication after pathogenic SIV infection. J Virol 2000; 74:7485.<br />

131. Lu S, Arthos J, Montefiori DC, et al. Simian immunodeficiency virus DNA vaccine trial<br />

in macaques. J Virol 1996; 70:3978.<br />

132. Barouch DH, Santra S, Schmitz JE, et al. Control of viremia and prevention of clinical<br />

AIDS in rhesus monkeys by cytokine-augmented DNA vaccination. Science 2000;<br />

290:486.<br />

133. Amara RR, Villinger F, Altman JD, et al. Control of a mucosal challenge and prevention<br />

of AIDS by a multiprotein DNA/MVA vaccine. Science 2001; 292:69.<br />

134. Buge SL, Murty L, Arora K, et al. Factors associated with slow disease progression in<br />

macaques immunized with an adenovirus-simian immunodeficiency virus (SIV) envelope<br />

priming-gp120 boosting regimen and challenged vaginally with SIVmac251. J Virol 1999;<br />

73:7430.<br />

135. Allen TM, O’Connor DH, Jing P, et al. Tat-specific cytotoxic T lymphocytes select <strong>for</strong><br />

SIV escape variants during resolution of primary viraemia. Nature 2000; 407:386.

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