Immunotherapy for Infectious Diseases
Immunotherapy for Infectious Diseases Immunotherapy for Infectious Diseases
Immunopathogenesis of HIV Disease 161 Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort Study, San Francisco City Cohort, ALIVE Study. Science 1996; 273:1856–1862. 24. Fauci AS. Multifactorial nature of human immunodeficiency virus disease: implications for therapy. Science 1993; 262:1011–1018. 25. Moore JP, Cao Y, Ho DD, Koup RA. Development of the anti-gp120 antibody response during seroconversion to human immunodeficiency virus type 1. J Virol 1994; 68:5142–5155. 26. Panteleo G, Demarest JF, Soudeys H, et al. Major expansion of CD8 T cells with a predominant V beta usage during the primary immune response to HIV. Nature 1994; 370:463–467. 27. Mackewicz CE,Yang LC, Lifson JD, Levy JA. Non-cytolytic CD8 T-cell anti-HIV responses in primary HIV-1 infection. Lancet 1994; 344:1671–1673. 28. Dye C, Scheele S, Dolin P, et al. Global burden of tuberculosis: estimated incidence, prevalence, and mortality by country. JAMA 1999; 282:677–686. 29. Pantaleo G, Fauci AS. New concepts in the immunopathogenesis of HIV infection. Annu Rev Immunol 1995; 13:487–512. 30. Cullen BR. HIV-1 auxilliary proteins: making connections in a dying cell. Cell 1998; 93:685–692. 31. Rosenberg ES, Walker BD. Characterization of HIV-1 specific T helper cells in acute and chronic infection. Immunol Lett 1999; 66:89–93. 32. Hellerstein M, Hanley MB, Ktzin BL, et al. Directly measured kinetics of circulating T lymphocytes in normal and HIV-1 infected humans. Nat Ned 1999; 5:83–89. 33. Douek DC, McFarland RD, Keisre PH, et al. Changes in thymic function with age and during the treatment of HIV infection. Nature 1998; 396:690–695. 34. Fan J, Bass HZ, Fahey JL. Elevated IFN-gamma and decreased IL-2 gene expression are associated with HIV infection. J Immunol 1993; 151:5031–5040. 35. Laurence J, Hodtsev A, Posnett DN. Suprantigen implicated in dependence of HIV-1 replication in T cells on TCR V beta expression. Nature 1992; 58:255–259. 36. Shearer GM. HIV-Induced Immunopathogenesis (review). Immunity 1998; 9:587–593. 37. Andersson J, Fehniger TE, Patterson BK, et al. Early reduction of immune activation in lymphoid tissue following highly active HIV therapy. AIDS 1998; 12:F123–F129. 38. Li TS, Tubiana R, Katlama C, et al. Long-lasting recovery in CD4 T-cell function and viralload reduction after highly active antiretroviral therapy in advanced HIV disease. Lancet 1998; 351:1682–1686. 39. Lederman MM, Conick E, Landay A, et al. Immunologic reponses associated with 12 weeks of antiretroviral therapy consisting of zidovudine, lamivudine, and ritonavir: results of AIDS clinical trials group protocol 315. J Infect Dis 1998; 178:70–79. 40. Connick E, Lederman MM, Kotzin BL, et al. Immune reconstitution in the first year of potent antiretroviral therapy and its relationship to virologic resonse. J Infect Dis 2000; 181:358–363. 41. Giorgi JV, Liu Z, Huitlin LE, et al. Elevated levels of CD38�CD8� T cells in HIV infection add to the prognostic value of low CD4� T cell levels: results of 6 years of followup. J Acquir Imm Defic Syndr 1993; 6:904–912.
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Immunopathogenesis of HIV Disease 161<br />
Development Study, Multicenter AIDS Cohort Study, Multicenter Hemophilia Cohort<br />
Study, San Francisco City Cohort, ALIVE Study. Science 1996; 273:1856–1862.<br />
24. Fauci AS. Multifactorial nature of human immunodeficiency virus disease: implications <strong>for</strong><br />
therapy. Science 1993; 262:1011–1018.<br />
25. Moore JP, Cao Y, Ho DD, Koup RA. Development of the anti-gp120 antibody response during<br />
seroconversion to human immunodeficiency virus type 1. J Virol 1994; 68:5142–5155.<br />
26. Panteleo G, Demarest JF, Soudeys H, et al. Major expansion of CD8 T cells with a predominant<br />
V beta usage during the primary immune response to HIV. Nature 1994;<br />
370:463–467.<br />
27. Mackewicz CE,Yang LC, Lifson JD, Levy JA. Non-cytolytic CD8 T-cell anti-HIV responses<br />
in primary HIV-1 infection. Lancet 1994; 344:1671–1673.<br />
28. Dye C, Scheele S, Dolin P, et al. Global burden of tuberculosis: estimated incidence, prevalence,<br />
and mortality by country. JAMA 1999; 282:677–686.<br />
29. Pantaleo G, Fauci AS. New concepts in the immunopathogenesis of HIV infection. Annu<br />
Rev Immunol 1995; 13:487–512.<br />
30. Cullen BR. HIV-1 auxilliary proteins: making connections in a dying cell. Cell 1998;<br />
93:685–692.<br />
31. Rosenberg ES, Walker BD. Characterization of HIV-1 specific T helper cells in acute and<br />
chronic infection. Immunol Lett 1999; 66:89–93.<br />
32. Hellerstein M, Hanley MB, Ktzin BL, et al. Directly measured kinetics of circulating T<br />
lymphocytes in normal and HIV-1 infected humans. Nat Ned 1999; 5:83–89.<br />
33. Douek DC, McFarland RD, Keisre PH, et al. Changes in thymic function with age and during<br />
the treatment of HIV infection. Nature 1998; 396:690–695.<br />
34. Fan J, Bass HZ, Fahey JL. Elevated IFN-gamma and decreased IL-2 gene expression are<br />
associated with HIV infection. J Immunol 1993; 151:5031–5040.<br />
35. Laurence J, Hodtsev A, Posnett DN. Suprantigen implicated in dependence of HIV-1 replication<br />
in T cells on TCR V beta expression. Nature 1992; 58:255–259.<br />
36. Shearer GM. HIV-Induced Immunopathogenesis (review). Immunity 1998; 9:587–593.<br />
37. Andersson J, Fehniger TE, Patterson BK, et al. Early reduction of immune activation in<br />
lymphoid tissue following highly active HIV therapy. AIDS 1998; 12:F123–F129.<br />
38. Li TS, Tubiana R, Katlama C, et al. Long-lasting recovery in CD4 T-cell function and viralload<br />
reduction after highly active antiretroviral therapy in advanced HIV disease. Lancet<br />
1998; 351:1682–1686.<br />
39. Lederman MM, Conick E, Landay A, et al. Immunologic reponses associated with 12<br />
weeks of antiretroviral therapy consisting of zidovudine, lamivudine, and ritonavir: results<br />
of AIDS clinical trials group protocol 315. J Infect Dis 1998; 178:70–79.<br />
40. Connick E, Lederman MM, Kotzin BL, et al. Immune reconstitution in the first year of<br />
potent antiretroviral therapy and its relationship to virologic resonse. J Infect Dis 2000;<br />
181:358–363.<br />
41. Giorgi JV, Liu Z, Huitlin LE, et al. Elevated levels of CD38�CD8� T cells in HIV infection<br />
add to the prognostic value of low CD4� T cell levels: results of 6 years of followup.<br />
J Acquir Imm Defic Syndr 1993; 6:904–912.