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AAPI’S NUTRITION GUIDE TO OPTIMAL HEALTH: USING PRINCIPLES OF FUNCTIONAL MEDICINE AND NUTRITIONAL GENOMICS b. Extensive Elimination Diet: Reduce intake of foods to a very low inflammatory diet, then gradually reintroduce foods while documenting symptoms. c. Food Sensitivity Testing: I have found that the use of the ALCAT has provided my family and my clients significant improvement in all measures of wellness; therefore, it has become the testing method of choice in my clinical practice. The test is designed to measure the innate immune response to food, allowing the patient to eliminate foods that are activating the immune system and causing downstream inflammation. IgG testing, or allergy testing, is used by some practitioners, however, there is question at this time as to whether the presence of an antibody to a food is a reliable predictor of a pathological response.(35,36) 4. Take a robust pharmaceutical grade nutrient regimen: a. L-glutamine will aid in gut cell regeneration. b. digestive enzymes may aid the digestive process. c. broad spectrum probiotics have been found to help reduce the inflammation. d. multivitamin and multi-mineral. 5. Journal: this process allows your client to discover the wide variety of responses their body has to certain foods, provide objective information about their diet, and understand and change food behaviors that may be driving pathological eating habits. Keep It Simple Consider a paradigm changing thought: Wellness is the NORMAL state. We work hard to get sick. Often, instead of ordering expensive testing, I counsel clients to start their wellness program by eating only what their grandparents would have eaten. Nearly everyone returns feeling significantly better! Concluding Thoughts Food sensitivity is a complicated problem because it is both the end result and a perpetuating factor in a vicious cycle of gastrointestinal dysfunctions. Food 82 2012 sensitivity is important because it reflects underlying metabolic, immunologic, and anatomic abnormalities. These include various degrees of intestinal flora abnormalities, intestinal hyper-permeability, anatomic damage to intestinal micro-structures, improper digestion and absorption, and chronic activation of the immune system leading to local and systemic inflammation. The benefit of a vicious cycle is that it can be broken at any point along the chain of events. When dealing with a complicated patient, I recommend looking at gastrointestinal health immediately. This may be as simple as recommending your patient stop milk and gluten products and journal symptoms for 2-4 weeks. This brief time period is not overwhelming and will allow the patient to ‚feel‛ the positive effects and establish ‚buy-in.‛ With a motivated or significantly ill patient, it may be appropriate to evaluate the stool for digestion, absorption, and dysbiosis and use ALCAT testing to guide their diet more specifically. There are no risks to food elimination and the benefits can be tremendous and immediate: 1. promote gut healing 2. reduce inflammation 3. reduce immune system activation 4. improve metabolic processes and reduce chronic disease Remember, WELLNESS IS THE DEFAULT STATE. From this perspective, complicated problems are simplified because understand that the body will return to a state of health as certain physiologic, psychologic, and metabolic stressors are removed. So peel back the layers and help your patient discover wellness! Start with gut health; you can’t go wrong. I wish you the best! Jamie Wright is a Board Certified ‚reformed‛ Gynecologist who fully embraced integrative medicine as he helped his wife overcome autoimmune disease and chronic pain. He is pursuing a Master’s Degree from the University of South Florida Medical School with a focus on Metabolic and Nutritional Medicine. He is also board certified by the American Academy of
AAPI’S NUTRITION GUIDE TO OPTIMAL HEALTH: USING PRINCIPLES OF FUNCTIONAL MEDICINE AND NUTRITIONAL GENOMICS Anti-Aging Medicine after completing Advanced Fellowship Training in Anti-Aging, Regenerative, and Functional Medicine. Dr. Wright knows that Wellness is the Natural State. He works with clients to help them achieve ‚LifeChange Through Wellness‛, a concept that leverages the power of health to create a vital life. Dr. Wright lectures and speaks to a variety of audiences. He delivers a motivational and educational message, centered around practical wellness principles. He enjoys challenging his audience to create a ‚Vicious Cycle of Wellness‛ in their lives, achieving greater satisfaction and performance in all aspects of life. Contact Jamie Wright at wrightjamie34@yahoo.com Website: www.CentersForBalancedLiving.com Disclosure Dr. Jamie Wright provides consultative services to Cell Science Systems, Inc. This work was not funded by Cell Science System References: 1. Alessandro Fiocchia,b and Anna Nowak-We grzyna,b. The fascinating world of molecular diagnosis in the management of food allergy: nondum matura est. Current Opinion in Allergy and Clinical Immunology 2011, 11:200–203. 2. Lidholm J, Ballmer-Weber BK, Mari A, Vieths S. Component-resolved diagnostics in food allergy. Curr Opin Allergy ClinImmunol. 2006 Jun;6(3):234-40. 3. Antico A, Pagani M, Vescovi PP, Bonadonna P, Senna G. Food-specific IgG4 lack diagnostic value in adult patients with chronic urticaria and other suspected allergy skin symptoms. Int Arch Allergy Immunol. 2011;155(1):52-6. Epub 2010 Nov 26. 4. Wüthrich B. Unproven techniques in allergy diagnosis. J Investig Allergol Clin Immunol. 2005;15(2):86-90. 5. Duncan BB, Schmidt MI. Chronic activation of the innate immune system may underlie the metabolic syndrome. Sao Paulo Med J. 2001; 119: 122-127. 6. Philpott H, Gibson P, Thien F. Irritable bowel syndrome - An inflammatory disease involving mast cells. Asia Pac Allergy. 2011 Apr;1(1):36-42. Epub 2011 Apr 26. 83 2012 7. Gupta S, Abu-Ghannam N. Probiotic fermentation of plant based products: possibilities and opportunities. Crit Rev Food Sci Nutr. 2012 Feb;52(2):183-99. 16 8. Vitali B, Ndagijimana M, Cruciani F, Carnevali P, Candela M, Guerzoni ME, Brigidi P. Impact of a synbiotic food on the gut microbial ecology and metabolic profiles. BMC Microbiol. 2010 Jan 7;10:4. 9. Gage, J. Understanding the role of probiotics in supporting digestive comfort. Nurs Stand. 2009 Sep 30- Oct 6;24(4):47-55; quiz 56. 10. Burcelin R, Serino M, Chabo C, Blasco-Baque V, Amar J. Gut microbiota and diabetes: from pathogenesis to therapeutic perspective.Acta Diabetol. 2011 Oct 2. 11. Roberfroid M, Gibson GR, Hoyles L, McCartney AL, Rastall R, Rowland I, Wolvers D, Watzl B, Szajewska H, Stahl B, Guarner F, Respondek F, Whelan K, Coxam V, Davicco MJ, Léotoing L, Wittrant Y, Delzenne NM, Cani PD, Neyrinck AM, Meheust A. Prebiotic effects: metabolic and health benefits. Br J Nutr. 2010 Aug;104 Suppl 2:S1-63. 12. Mayer EA. Gut feelings: the emerging biology of gut-brain communication. Nat Rev Neurosci. 2011 Jul 13;12(8):453-66. doi: 10.1038/nrn3071. 13. Romijn JA, Corssmit EP, Havekes LM, Pijl H. Gut- brain axis. Curr Opin Clin Nutr Metab Care. 2008 Jul;11(4):518-21. 14. Karlsson CL, Molin G, Cilio CM, Ahrné S. The pioneer gut microbiota in human neonates vaginally born at term-a pilot study. Pediatr Res. 2011 Sep;70(3):282-6. 15. Richaud-Patin Y, Soto-Vega E, Llorente L. The gut: beyond immunology. Reumatol Clin. 2005 Aug;1(2):121-8. Epub 2008 Dec 20. 16. La Rosa M, Lionetti E, Leonardi S, Salpietro A, Bianchi L, Salpietro C, Miraglia Del Giudice M, Ciprandi G, Marseglia GL. Specific immunotherapy in children: the evidence. Int J Immunopathol Pharmacol. 2011 Oct;24(4 Suppl):69- 78. 17. Fessler MB, Rudel LL, Brown JM. Toll-like receptor signaling links dietary fatty acids to the metabolic syndrome. Curr Opin Lipidol. 2009 Oct;20(5):379-85. 18. Hoj L. Diagnostic value of ALCAT test in intolerance to food additives compared with double blind placebo controlled oral challenges. J Alleg Clin Imm. 1996: No1 of 3. 19. Mele MC. Immune Cell Competence following In- Vitro challenge with ALCAT positive foods [English Translation]. Biotikos, Anno 1-Numero 1, Guigno 2000. 20. Canani RB, Di Costanzo M, Leone L, Bedogni G, Brambilla P, Cianfarani S, Nobili V, Pietrobelli A,
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