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functional medicine and nutritional genomics - American Association ...

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AAPI’S NUTRITION GUIDE TO OPTIMAL HEALTH: USING PRINCIPLES OF FUNCTIONAL MEDICINE AND NUTRITIONAL GENOMICS<br />

provide optimal immune stimulation <strong>and</strong> will be<br />

manageable for most patients.<br />

Stress can play an important role in interfering<br />

with immune health, in causing inflammation, <strong>and</strong><br />

in disrupting hormonal balance. The fourth pillar,<br />

stress management, is a general term under which<br />

spirituality <strong>and</strong> living with meaning or purpose can<br />

be included. Patients should be encouraged to<br />

meditate, to pray, do yoga, tai chi, or anything<br />

else that gives them relaxation, peace <strong>and</strong> a<br />

sense of inner strength. One can also use<br />

‚quantum biofeedback‛ <strong>and</strong> ‚EFT‛ (Emotional<br />

Freedom Technique) to help reduce stress <strong>and</strong><br />

improve emotional balance <strong>and</strong> well-being.<br />

The fifth pillar is detoxification, a subject curiously<br />

ignored in conventional <strong>medicine</strong>. Heavy metals,<br />

for example, are known immune disruptors <strong>and</strong><br />

many of them are frankly carcinogenic. Those<br />

patients with body burdens of these substances<br />

need chelation to help restore immune competence<br />

<strong>and</strong> cellular energy. Pesticides, plasticizers, <strong>and</strong><br />

many other environmental toxins are endocrine<br />

disruptors <strong>and</strong> have been implicated in the rising<br />

incidence of breast <strong>and</strong> prostate cancer as well as<br />

other types of cancer. In addition to chelation, it<br />

is good to offer far-infrared sauna treatments <strong>and</strong><br />

colon hydrotherapy to aid in the detoxification<br />

process. The first pillar, a clean diet, will also<br />

limit toxin exposure. Vegetable juicing <strong>and</strong> eating<br />

high-fiber food will speed elimination <strong>and</strong><br />

detoxification as well.<br />

The final pillar is hormone balancing. One<br />

important example of the hormone problem is the<br />

growing epidemic of unrecognized hypothyroidism.<br />

It has been recently noted in studies that breast<br />

cancer is associated with high TSH values (a<br />

symptom of hypothyroidism). Hypothyroidism<br />

suppresses immune function in general. Many<br />

patients have cancers that are sensitive to<br />

hormones. In fact, it is sometimes the presence of<br />

higher levels of toxic estrogen metabolites (like<br />

4.-OH <strong>and</strong> 16-OH estrone) that may have<br />

predisposed the patient to cancer in the first<br />

place. Fortunately, the thyroid gl<strong>and</strong> can<br />

sometimes be naturally stimulated (in some cases<br />

the removal of toxins from the body can aid in<br />

138<br />

this process). For other patients, replacement of<br />

thyroid hormone is indicated. In the case of toxic<br />

estrogen metabolites, diet change, simple<br />

supplements, <strong>and</strong> exercise can lower these levels.<br />

There are other hormonal issues that can also<br />

play a role. All must be taken into account in<br />

order to optimize treatment.<br />

All these six pillars are covered, but what about<br />

aggressively killing the cancer cells that have<br />

appeared in our body? Insulin Potentiation Therapy<br />

Low Dose― chemotherapy (IPT) is an effective,<br />

yet gentle way of killing cancer cells. The theory<br />

behind IPT could not be more logical. Cancer<br />

cells in general concentrate sugar through their<br />

abundance of insulin receptors as described earlier.<br />

If a small measured dose of insulin is given, the<br />

cancer cells become selectively more permeable,<br />

<strong>and</strong> then the insulin receptor sites are maximally<br />

saturated with insulin (the therapeutic moment).<br />

Very small doses of chemotherapy agents are then<br />

introduced into the body <strong>and</strong> these doses are<br />

effectively concentrated into the cancer cells<br />

providing enhanced killing powers with a much<br />

lower side effect profile.<br />

How do we choose among different chemotherapy<br />

drugs? As with conventional oncology, we can<br />

choose an agent that has been shown to be<br />

effective in most patients with a specific type of<br />

tumor. However, in the interest of a truly<br />

individualized approach to treatment, we can send<br />

the patient’s blood to a laboratory in Europe that<br />

will test the blood for circulating tumor cells <strong>and</strong><br />

then test these for resistance to various<br />

chemotherapy drugs. This will allow us to pick out<br />

the most effective drugs for each individual patient.<br />

These drugs could be very different from the<br />

st<strong>and</strong>ard protocols in oncology. This laboratory will<br />

also test for alternative (natural <strong>and</strong><br />

nontraditional) agents that can help overcome<br />

chemotherapy resistance or even directly kill<br />

cancer cells. Natural killer cell function (a<br />

measure of immune function) is also assayed<br />

(tested) <strong>and</strong> information is given as to the most<br />

effective agents to more effectively attack the<br />

cancer.<br />

2012

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