UNIVERSITY OF CALIFORNIA, SAN DIEGO

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4 CALIFORNIA, SAN DIEGO Lauren J. Pouwels, Liping Zhang, Nam H. Chan, Pieter C. Dorrestein and Rebekka M. Wachter, Kinetic Isotope Effect Studies on the de Novo Rate of Chromophore Formation in Fast- and Slow-Maturing GFP Variants, Biochemistry, 47, 10111-10122 (2008). Dario Meluzzi, Wei Hao Zheng, Mary Hensler, Victor Niz- et and Pieter C. Dorrestein, Top-down mass spectrometry on low-resolution instruments: Characterization of phosphopantetheinylated carrier domains in polyketide and non-ribosomal biosynthetic pathways, Bioorg. Med. Chem. Lett, 18, 3107-3111 (2008). Jeremiah W. Hanes, Kristin E. Burns, David G. Hilmey, Abhishek Chatterjee, Pieter C. Dorrestein and Tadhg P. Begley, Mechanistic Studies on Pyridoxal Phosphate Synthase: The Reaction Pathway Leading to a Chromophoric Intermediate, J. Am. Chem. Soc, 130, 3043-3052 (2008). Eduardo Esquenazi, Cameron Coates, Luke Simmons, David Gonzalez, William H. Gerwick and Pieter C. Dorrestein, Visualizing the spatial distribution of secondary metabolites produced by marine cyanobacteria and sponges via MALDI- TOF imaging, Mol. BioSyst, 4, 562-570 (2008). Jacky Chi Ki Ngo, Kayla Giang, Sutapa Chakrabarti, Chen-Ting Ma, Nhat Huynh, Jonathan C. Hagopian, Pieter C. Dorrestein, Xiang-Dong Fu, Joseph A. Adams and Gourisankar Ghosh, A sliding docking interaction is essential for sequential and processive phosphorylation of an SR protein by SRPK1, Mol. Cell, 29, 563-576 (2008). Jian Zhang, Steven G. Van Lanen, Jianhua Ju, Wen Liu, Pieter C. Dorrestein, Wenli Li, Neil L. Kelleher and Ben Shen, A phosphopantetheinylating polyketide synthase producing a linear polyene to initiate enediyne antitumor antibiotic biosynthesis, Proc. Natl. Acad. Sci. U. S. A, 105, 1460- 1465 (2008). T. Luke Simmons, R. Cameron Coates, Benjamin R. Clark, Niclas Engene, David Gonzalez, Eduardo Esquenazi, Pieter C. Dorrestein and William H. Gerwick, Biosynthetic origin of natural products isolated from marine microorganism-in- vertebrate assemblages, Proc. Natl. Acad. Sci. U. S. A, 105, 4587-4594 (2008). Shaun W. Lee, Douglas A. Mitchell, Andrew L. Markley, Mary E. Hensler, David Gonzalez, Aaron Wohlrab, Pieter C. Dorrestein, Victor Nizet and Jack E. Dixon, Discovery of a widely distributed toxin biosynthetic gene cluster, Proc. Natl. Acad. Sci. U. S. A, 105, 5879-5884 (2008). ELLIS, ARTHUR B. (b.1951) Professor. B.Sc, 1973, Caltech; Ph.D, 1977, MIT. Materials Chemistry. TEL: (858) 534-3526 FAX: (858) 534-3868 Email: abellis@ucsd.edu Arthur B. Ellis, Integrating research and education to create a dynamic physical chemistry curriculum, ACS Symp. Ser, 973, 40-43 (2007). FAHEY, ROBERT C. (b.1936) Professor Emeritus. B.S, 1957, University of California, Berkeley; Ph.D, 1963, University of Chicago. Guggenheim Foundation Fellowship, 1970-1971, Laboratory Molecular Biology, Medical Research Council, Cambridge, England; American Cancer Society, Cancer Scholar, 1988-1989, Cancer Research Campaign Gray Laboratory, Northwood, England. Biochemistry. Thiol biochemistry; current emphasis is on the biosynthesis and metabolism of mycothiol in Mycobacterium tuberculosis and of bacillithiol in Staphylococcus aureus as targets for new antibiotics. TEL: (858) 534-2163 FAX: (858) 534-4864 Email: rcfahey@ucsd.edu Nathan I. Nicely, Derek Parsonage, Carleitta Paige, Gerald L. Newton, Robert C. Fahey, Roberta Leonardi, Suzanne Jackowski, T. Conn Mallett and Al Claiborne, Structure of the Type III Pantothenate Kinase from Bacillus anthracis at 2.0 Å Resolution: Implications for Coenzyme A-Dependent Redox Biology, Biochemistry, 46, 3234-3245 (2007). Krzysztof P. Bzymek, Gerald L. Newton, Philong Ta and Robert C. Fahey, Mycothiol import by Mycobacterium smegmatis and function as a resource for metabolic precursors and energy production, J. Bacteriol, 189, 6796-6805 (2007). Gerald L. Newton, Paul R. Jensen, John B. MacMillan, William Fenical and Robert C. Fahey, An N-acyl homolog of mycothiol is produced in marine actinomycetes, , 190, 547- 557 (2008). Todd Johnson, Gerald L. Newton, Robert C. Fahey and Mamta Rawat, Unusual production of glutathione in Actinobacteria, Arch. Microbiol, 191, 89-93 (2008). Gerald L. Newton, Nancy Buchmeier and Robert C. Fahey, Biosynthesis and functions of mycothiol, the unique protective thiol of Actinobacteria, Microbiol. Mol. Biol. Rev, 72, 471-494 (2008). Gerald L. Newton and Robert C. Fahey, Regulation of mycothiol metabolism by � the stabilization of reactive transition metal fragments. Modulation and control of redox equivalents for chemical transformations through the explicit use of redox-active ligands and/or spectator agents. Construction of novel transition metal-stabilized main group species. TEL: (858) 822-7478 FAX: (858) 822-4222 Web: figueroagroup.ucsd.edu/home.htm Email: jsfig@ucsd.edu Brian J. Fox, Queena Y. Sun, Antonio G. DiPasquale, Alexander R. Fox, Arnold L. Rheingold and Joshua S. Figueroa, Solution Behavior and Structural Properties of Cu(I) Complexes Featuring m-Terphenyl Isocyanides, Inorg. Chem. (Washington, DC, U. S.), 47, 9010-9020 (2008). FOX, MARYE ANNE (b.1947) Professor, Chancellor. B.S, 1969, Notre Dame College; M.S, 1970, Cleveland State University; Ph.D, 1974, Dartmouth College. Postdoctoral fellow, 1974-1976, University of Maryland. Organic Chemistry; Photochemistry. Physical organic chemsitry at surfaces; self-assembled monolayers; photoelectrochemistry; spectroscopy of dendrimers. TEL: (858) 534-3135 FAX: (858) 534-6523 Web: www.chancellor-ucsd.edu Email: mafox@ucsd.edu No publication information submitted for this edition. GALPERIN, M. (b.1969) Assistant Professor. M.Sc, 1991, Ural State University; Ph.D, 2003, Tel Aviv University. Postdoctoral Fellow, 2002-2003, Duke University; Senior Research Associate, 2003-2007, Northwestern University; Director’s Postdoctoral Fellow, 2007-2008, Los Alamos National Laboratory. Chemical Physics; Theoretical Chemistry. Electron transport in condensed phases. Dissipation and relaxation processes. Open quantum systems out of equilibrium. Molecular electronics. TEL: (858) 246-0511 FAX: (858) 534-7244 Web: galperingroup.ucsd.edu/ Email: migalperin@ucsd.edu M. Galperin and D. N. Beratan, Simulation of scanning tunneling microscope images of 1,3-cyclohexadiene bound to a silicon surface, Journal of Physical Chemistry B, 109, 1473-1480 (2005). M. Galperin, A. Nitzan, M. A. Ratner and D. R. Stewart, Molecular transport junctions: Asymmetry in inelastic tunneling processes, Journal of Physical Chemistry B, 109, 8519-8522 (2005). M. Galperin, M. A. Ratner and A. Nitzan, Hysteresis, switching and negative differential resistance in molecular junctions: A polaron model, Nano Letters, 5, 125-130 (2005). M. Galperin and A. Nitzan, Current-induced light emission and light-induced current in molecular-tunneling junctions, Physical Review Letters, 95, 206802 (2005). M. Galperin and A. Nitzan, Optical properties of current carrying molecular wires, Journal of Chemical Physics, 124, 234709 (2006). M. Galperin, A. Nitzan and M. A. Ratner, Resonant inelastic tunneling in molecular junctions, Physical Review B, 73, 045314 (2006). M. Galperin, A. Nitzan and M. A. Ratner, Inelastic tunneling effects on noise properties of molecular junctions, Physical Review B, 74, 075326 (2006). M. Galperin, A. Nitzan and M. A. Ratner, Molecular transport junctions: Current from electronic excitations in the leads, Physical Review Letters, 96, 166803 (2006). S. Yeganeh, M. Galperin and M. A. Ratner, Switching in molecular transport junctions: Polarization response, Journal of American Chemical Society, 129, 13313-13320 (2007). M. Galperin, M. A. Ratner and A. Nitzan, Molecular transport junctions: Vibrational effects, Journal of Physics: Condensed Matter, 19, 103201 (2007). M. Galperin, A. Nitzan and M. A. Ratner, Inelastic effects in molecular junctions in the Coulomb and Kondo regimes: Nonequilibrium equation-of-motion approach, Physical Review B, 76, 035301 (2007). M. Galperin, A. Nitzan and M. A. Ratner, Heat conduction in molecular transport junctions, Physical Review B, 75, 155312 (2007). M. Galperin and S. Tretiak, Linear optical response of current-carrying molecular junction: A NEGF-TDDFT approach, Journal of Chemical Physics, 128, 124705 (2008). M. Galperin, A. Nitzan and M. A. Ratner, The non-linear response of molecular junctions: The polaron model revisited, Journal of Physics: Condensed Matter, 20, 374107 (2008). M. Galperin, A. Nitzan and M. A. Ratner, Inelastic effects in molecular junction transport: scattering and self-consistent calculations for the Seebeck coefficient, Molecular Physics, University; M.S, 1988, Albert Einstein College of Medicine; Ph.D, 1991, Albert Einstein College of Medicine. Postdoctoral Fellow, 1991-1995, Yale University. Regu- lation of gene expression; high resolution x-ray crystallography, mutational and biochemical approaches to study biologically active protein/DNA and protein/RNA complexes. TEL: (858) 822-0469 FAX: (858) 534-7042 Email: gghosh@ucsd.edu Publication list has not been verified by the department. Devin Drew, Eriko Shimada, Kim Huynh, Simon Bergqvist, Rashmi Talwar, Michael Karin and Gourisankar Ghosh, Inhibitor �B Kinase � Binding by Inhibitor �B Kinase �, Biochemistry, 46, 12482-12490 (2007). Soumen Basak, Hana Kim, Jeffrey D. Kearns, Vinay Ter- gaonkar, Ellen O’Dea, Shannon L. Werner, Chris A. Benedict, Carl F. Ware, Gourisankar Ghosh, Inder M. Verma and Alexander Hoffmann, A fourth I�B protein within the NF-�B signaling module, Cell (Cambridge, MA, U. S.), 128, 369- 381 (2007). Anu K. Moorthy, Tom Huxford and Gourisankar Ghosh, Structural aspects of NF-�B and I�B proteins, Handb. Transcr. Factor NF-kappaB, 9-24 (2007). Randall Lukasiewicz, Adolfo Velazquez-Dones, Nhat Huynh, Jonathan Hagopian, Xiang-Dong Fu, Joseph Adams and Gourisankar Ghosh, Structurally Unique Yeast and Mammalian Serine-Arginine Protein Kinases Catalyze Evolutionarily Conserved Phosphorylation Reactions, J. Biol. Chem, 282, 23036-23043 (2007). Randall Lukasiewicz, Bradley Nolen, Joseph A. Adams and Gourisankar Ghosh, The RGG Domain of Npl3p Recruits Sky1p Through Docking Interactions, J. Mol. Biol, 367, 249-261 (2007). Anu K. Moorthy, De-Bin Huang, Vivien Ya-Fan Wang, Don Vu and Gourisankar Ghosh, X-ray Structure of a NF-�B p50/RelB/DNA Complex Reveals Assembly of Multiple Dimers on Tandem �B Sites, J. Mol. Biol, 373, 723-734 (2007). Stephanie D. Shaw, Sutapa Chakrabarti, Gourisankar Ghosh and Adrian R. Krainer, Deletion of the N-terminus of SF2/ASF permits RS-domain-independent pre-mRNA splicing, PLoS One, 2, No pp. given (2007). Jacky Chi Ki Ngo, Justin Gullingsrud, Kayla Giang, Me- linda Jean Yeh, Xiang-Dong Fu, Joseph A. Adams, J. Andrew McCammon and Gourisankar Ghosh, SR Protein Kinase 1 Is Resilient to Inactivation, Structure (Cambridge, MA, U. S.), 15, 123-133 (2007). Erika Mathes, Ellen L. O’Dea, Alexander Hoffmann and Gourisankar Ghosh, NF-�B dictates the degradation pathway of I�B�, EMBO J, 27, 1357-1367 (2008). Erika Mathes, Ellen L. O’Dea, Alexander Hoffmann and Gourisankar Ghosh, NF-�B dictates the degradation pathway of I�B�. [Erratum to document cited in CA148:555634], EMBO J, 27, 1421 (2008). Eileen J. Kennedy, Gourisankar Ghosh and Lorraine Pillus, Identification of Functionally Distinct Regions That Mediate Biological Activity of the Protein Kinase A Homolog Tpk2, J. Biol. Chem, 283, 1084-1093 (2008). Amanda J. Fusco, Olga V. Savinova, Rashmi Talwar, Jeffrey D. Kearns, Alexander Hoffmann and Gourisankar Ghosh, Stabilization of RelB Requires Multidomain Interactions with p100/p52, J. Biol. Chem, 283, 12324-12332 (2008). Malini Sen and Gourisankar Ghosh, Transcriptional Out- come of Wnt-Frizzled Signal Transduction in Inflammation: Evolving Concepts, J. Immunol, 181, 4441-4445 (2008). Chen-Ting Ma, Adolfo Velazquez-Dones, Jonathan C. Hagopian, Gourisankar Ghosh, Xiang-Dong Fu and Joseph A. Adams, Ordered Multi-site Phosphorylation of the Splicing Factor ASF/SF2 By SRPK1, J. Mol. Biol, 376, 55-68 (2008). Stephanie M. E. Truhlar, Erika Mathes, Carla F. Cervantes, Gourisankar Ghosh and Elizabeth A. Komives, Pre-folding I�B� Alters Control of NF-�B Signaling, J. Mol. Biol, 380, 67-82 (2008). Jonathan C. Hagopian, Chen-Ting Ma, Bryan R. Meade, Claudio P. Albuquerque, Jacky Chi Ki Ngo, Gourisankar Ghosh, Patricia A. Jennings, Xiang-Dong Fu and Joseph A. Adams, Adaptable Molecular Interactions Guide Phosphoryl- ation of the SR Protein ASF/SF2 by SRPK1, J. Mol. Biol, 382, 894-909 (2008). Jacky Chi Ki Ngo, Kayla Giang, Sutapa Chakrabarti, Chen-Ting Ma, Nhat Huynh, Jonathan C. Hagopian, Pieter C. Dorrestein, Xiang-Dong Fu, Joseph A. Adams and Gourisankar Ghosh, A sliding docking interaction is essential for sequential and processive phosphorylation of an SR protein by SRPK1, Mol. Cell, 29, 563-576 (2008). GHOSH, PARTHO (b.1962) Professor. B.S, 1985, Yale University; Ph.D, 1992, University of California, San Francisco. Irvington Institute for Medical Research, 1993-1997, Harvard University. Biochemistry; Structural R and the thiol redox sensor anti-sigma factor RsrA, Mol. Microbiol, 68, 805-809 (2008). FIGUEROA, JOSHUA S. (b.1978) Assistant Professor. B.Sc, 2000, University of Delaware; Ph.D, 2005, M.I.T. NIH Postdoctoral Resarch Fellow, 2005-2007, Columbia University. Inorganic Chemistry; Organome- 106, 397-404 (2008). M. Galperin, A. Nitzan and M. A. Ratner, Inelastic transport in the Coulomb blockade regime within a nonequilibrium atomic limit, Physical Review B, 78, 125320 (2008). M. Galperin, M. A. Ratner, A. Nitzan and A. Troisi, Nuclear coupling and polarization in molecular transport junctions: Beyond tunneling to function, Science, 319, 1056-1060 Biology. We are interested in understanding the interactions between microbial pathogens and targets on host mammalian cells. We are studying these interactions using the tools of biochemistry and structural biology. In understanding the detailed interaction of pathogen and host macromolecules, we aim to probe fundamental istallic Chemistry. Research in the Figueroa Group broadly (2008). sues in mammalian cell biology and to provide informaencompasses aspects of synthetic inorganic and organometallic chemistry. Areas of interest include: Design and GHOSH, GOURISANKAR (b.1959) Asst. Professor. tion for the design of antimicrobial therapeutics. TEL: (858) 822-1139 FAX: (858) 822-2871 implementation of highly tailored ancillary ligands for B.Sc, 1983, St. Xaviers’ College; M.Sc, 1985, Calcutta Web: pghosh.ucsd.edu
CALIFORNIA, SAN DIEGO 5 Email: pghosh@ucsd.edu Sybil C. Lang Hrtska, Melissa M. Kemp, Eva M. Munoz, Omaira Azizad, Mani Banerjee, Catarina Raposo, Jyothi Kumaran, Partho Ghosh and Robert J. Linhardt, Investigation of the Mechanism of Binding between Internalin B and Heparin Using Surface Plasmon Resonance, Biochemistry, 46, 2697- 2706 (2007). Loren Rodgers, Alicia Gamez, Roland Riek and Partho Ghosh, The Type III Secretion Chaperone SycE Promotes a Localized Disorder-to-Order Transition in the Natively Unfolded Effector YopE, J. Biol. Chem, 283, 20857-20863 (2008). Jason L. Miller, Johanne Le Coq, Asher Hodes, Roman Barbalat, Jeff F. Miller and Partho Ghosh, Selective ligand recognition by a diversity-generating retroelement variable protein, PLoS Biol, 6, 1195-1207 (2008). Case McNamara, Annelies S. Zinkernagel, Pauline Macheboeuf, Madeleine W. Cunningham, Victor Nizet and Partho Ghosh, Coiled-Coil Irregularities and Instabilities in Group A Streptococcus M1 Are Required for Virulence, Science (Washington, DC, U. S.), 319, 1405-1408 (2008). GIANNESCHI, NATHAN CLAUDE Assistant Professor. B.Sc, 1999, University of Adelaide; Ph.D, 2005, Northwestern University. Dow Chemical Foundation Fellow, 2005-2008, The Scripps Research Institute. Biomaterials; Bioorganic Chemistry. TEL: (858) 246- 0857 FAX: (858) 534-0202 Web: gianneschigroup.ucsd.edu/home.htm Nathan C. Gianneschi and M. Reza Ghadiri, Design of molecular logic devices based on a programmable DNA-regulated semisynthetic enzyme, Angew. Chem., Int. Ed, 46, 3955- 3958 (2007). Martin S. Masar, III, Nathan C. Gianneschi, Christopher G. Oliveri, Charlotte L. Stern, SonBinh T. Nguyen and Chad A. Mirkin, Allosterically Regulated Supramolecular Catalysis of Acyl Transfer Reactions for Signal Amplification and Detection of Small Molecules, J. Am. Chem. Soc, 129, 10149- 10158 (2007). Nathan C. Gianneschi, Supramolecular allosteric catalysts. (D) HARPER, E. (b.1930) Professor Emeritus. B.S, 1952, City College of New York; M.A, 1961, Brooklyn College; Ph.D, 1966, Albert Einstein College of Medicine. Postdoctoral Fellowship, 1966-1967, Weizmann Institute of Science, Rehovot, Israel; Resident Fellow, Medicine, 1967-1968, Harvard Medical School. Collagen metabolism; structure-function aspects of the collagenases. TEL: (619) 534-4177 TEL: (619) 534-4861 Email: eharper@ucsd droxyethyl)ethylenediamine, Inorg. Chem. (Washington, DC, U. S.), 46, 8111-8113 (2007). Patrick L. Feng, Christopher C. Beedle, Wolfgang Wernsdorfer, Changhyun Koo, Motohiro Nakano, Stephen Hill and David N. Hendrickson, Heterometallic Cubane Single-Molecule Magnets, Inorg. Chem. (Washington, DC, U. S.), 46, 8126-8128 (2007). Wen-Guo Wang, Ai-Ju Zhou, Wei-Xiong Zhang, Ming- Liang Tong, Xiao-Ming Chen, Motohiro Nakano, Christopher C. Beedle and David N. Hendrickson, Giant Heterometallic Cu17Mn28 Cluster with Td Symmetry and High-Spin Ground State, J. Am. Chem. Soc, 129, 1014-1015 (2007). G. de Loubens, A. D. Kent, V. Krymov, G. J. Gerfen, C. C. Beedle and D. N. Hendrickson, High frequency EPR on dilute solutions of the single molecule magnet Ni4, J. Appl. Phys, 103, 07B910-1-07B910-3 (2007). G. de Loubens, G. D. Chaves-O’Flynn, A. D. Kent, C. Ramsey, E. del Barco, C. Beedle and D. N. Hendrickson, Magnetization and EPR studies of the single molecule magnet Ni4 with integrated sensors, J. Appl. Phys, 101, 09E104- 1-09E104-3 (2007). Anthony Wilson, En-Che Yang, David N. Hendrickson and Stephen Hill, On the validity of the giant spin approximation and its application to single-molecule magnets, Polyhedron, 26, 2065-2068 (2007). Christopher C. Beedle, Katie J. Heroux, Motohiro Nakano, Antonio G. DiPasquale, Arnold L. Rheingold and David N. Hendrickson, Antiferromagnetic tetranuclear manganese complex: Wheel or dicubane?, Polyhedron, 26, 2200-2206 (2007). Jon Lawrence, Chris C. Beedle, En-Che Yang, James Ma, Stephen Hill and David N. Hendrickson, High frequency electron paramagnetic resonance (HFEPR) study of a high spin Co(II) complex, Polyhedron, 26, 2299-2303 (2007). M. Bal, J. R. Friedman, W. Chen, M. T. Tuominen, C. C. Beedle, E. M. Rumberger and D. N. Hendrickson, Radiationand phonon-bottleneck-induced tunneling in the Fe8 singlemolecule magnet, EPL, 82, 17005 (2008). G. de Loubens, D. A. Garanin, C. C. Beedle, D. N. Hendrickson and A. D. Kent, Magnetization relaxation in the single-molecule magnet Ni4 under continuous microwave irra- diation, EPL, 83, 83, 37006 (2008). Christopher C. Beedle, Casey J. Stephenson, Katie J. Heroux, Wolfgang Wernsdorfer and David N. Hendrickson, Pho- toluminescent Mn4 Single-Molecule Magnet, Inorg. Chem. (Washington, DC, U. S.), 47, 10798-10800 (2008). Jon Lawrence, En-Che Yang, Rachel Edwards, Marilyn M. Olmstead, Chris Ramsey, Naresh S. Dalal, Peter K. Gantzel, Stephen Hill and David N. Hendrickson, Disorder and Inter- molecular Interactions in a Family of Tetranuclear Ni(II) Complexes Probed by High-Frequency Electron Paramagnetic Resonance, Inorg. Chem. (Washington, DC, U. S.), 47, 1965-1974 (2008). Patrick L. Feng, Christopher C. Beedle, Changhyun Koo, sity of Ulm, Germany; Ph.D, 1996, Max-Planck-Institute for Biochemistry/Ludwig-Maximilians-University, Munich. Postdoctoral Fellow, 1996-1998, IBMC/CNRS, Strasbourg, France; Research Associate, 1999-2000, Me- morial Sloan-Kettering Cancer Center, New York, NY; Senior Research Scientist, 2001, Memorial Sloan-Kettering Cancer Center, New York, NY. Bioorganic Chemistry; Crystallography. TEL: (858) 534-4467 FAX: (858) 534-0202 Web: tch.ucsd.edu Email: tch@ucsd.edu Sergey M. Dibrov, Hillary Johnston-Cox, Yi-Hsin Weng and Thomas Hermann, Functional architecture of HCV IRES domain II stabilized by divalent metal ions in the crystal and in solution, Angew. Chem., Int. Ed, 46, 226-229 (2007). Christopher M. Barbieri, Malvika Kaul, Melanie Bozza- Hingos, Fang Zhao, Yitzhak Tor, Thomas Hermann and Daniel S. Pilch, Defining the molecular forces that determine the impact of neomycin on bacterial protein synthesis: impor- tance of the 2’-amino functionality, Antimicrob. Agents Chemother, 51, 1760-1769 (2007). Yuefen Zhou, Vlad E. Gregor, Benjamin K. Ayida, Geof- frey C. Winters, Zhongxiang Sun, Douglas Murphy, Greg Haley, Dwight Bailey, Jamie M. Froelich, Sarah Fish, Steph- en E. Webber, Thomas Hermann and Daniel Wall, Synthesis and SAR of 3,5-diamino-piperidine derivatives: novel antibacterial translation inhibitors as aminoglycoside mimetics, Bioorg. Med. Chem. Lett, 17, 1206-1210 (2007). Thomas Hermann, Valentina Tereshko, Eugene Skripkin and Dinshaw J. Patel, Apramycin recognition by the human ribosomal decoding site, Blood Cells, Mol., Dis, 38, 193-198 (2007). Konstantin H. Dragnev, W. Jeffrey Petty, Sumit J. Shah, Lionel D. Lewis, Candice C. Black, Vincent Memoli, William C. Nugent, Thomas Hermann, Andres Negro-Vilar, James R. Rigas and Ethan Dmitrovsky, A Proof-of-Principle Clinical Trial of Bexarotene in Patients with Non-Small Cell Lung Cancer, Clin. Cancer Res, 13, 1794-1800 (2007). Jerod Parsons and Thomas Hermann, Conformational flex- ibility of ribosomal decoding-site RNA monitored by fluorescent pteridine base analogues, Tetrahedron, 63, 3548-3552 (2007). Qiang Zhao, Qing Han, Charles R. Kissinger, Thomas Hermann and Peggy A. Thompson, Structure of hepatitis C virus IRES subdomain IIa, Acta Crystallogr., Sect. D: Biol. Crystallogr, D64, 436-443, S436/1-S436/3 (2008). Yuefen Zhou, Stephen E. Webber, Douglas E. Murphy, Lian-Sheng Li, Peter S. Dragovich, Chinh V. Tran, Zhongxiang Sun, Frank Ruebsam, Amit M. Shah, Mei Tsan, Richard E. Showalter, Rupal Patel, Bin Li, Qiang Zhao, Qing Han, Thomas Hermann, Charles R. Kissinger, Laurie LeBrun, Ma- ria V. Sergeeva and Leo Kirkovsky, Novel HCV NS5B polymerase inhibitors derived from 4-(1’,1’-dioxo-1’,4’-dihydro- 1’�6-benzo[1’,2’,4’]thiadiazin-3’-yl)-5-hydroxy-2H-pyrida- No publication information submitted for this edition. Wolfgang Wernsdorfer, Motohiro Nakano, Stephen Hill and David N. Hendrickson, Heterometallic Integer-Spin Ana- logues of S = zin-3-ones. Part 1: Exploration of 7’-substitution of benzothiadiazine, Bioorg. Med. Chem. Lett, 18, 1413-1418 (2008). 9/2 HAYMET, A. D. J. Vice Chancellor and Dean, Marine Sciences. B.Sc, 1978, University of Sydney; Ph.D, 1981, University of Chicago; D.Sc, 1997, University of Sydney. Physical Chemistry. Nucleation, clathrates, freezing, anti-freeze proteins in fish. TEL: (858) 534-2827 FAX: (858) 453-0167 Mn4 Cubane Single-Molecule Magnets, Inorg. Chem. (Washington, DC, U. S.), 47, 3188-3204 (2008). Sonali J. Shah, Christopher M. Ramsey, Katie J. Heroux, James R. O’Brien, Antonio G. DiPasquale, Arnold L. Rhein- gold, Enrique del Barco and David N. Hendrickson, Wheel- Shaped Mn16 Single-Molecule Magnets, Inorg. Chem. Yuefen Zhou, Lian-Sheng Li, Peter S. Dragovich, Douglas E. Murphy, Chinh V. Tran, Frank Ruebsam, Stephen E. Webber, Amit M. Shah, Mei Tsan, April Averill, Richard E. Showalter, Rupal Patel, Qing Han, Qiang Zhao, Thomas Hermann, Charles R. Kissinger, Laurie LeBrun and Maria V. Sergeeva, Novel HCV NS5B polymerase inhibitors derived from 4-(1’,1’-dioxo-1’,4’-dihydro-1’�6-benzo[1’,2’,4’]thia- Web: sio.ucsd.edu/About/Director/ Email: haymet@ucsd.edu Publication list has not been verified by the department. Andrzej Wierzbicki, Pranav Dalal, Thomas E. Cheatham, III, Jared E. Knickelbein, A. D. J. Haymet and Jeffry D. Madura, Antifreeze proteins at the ice/water interface: Three calculated discriminating properties for orientation of type I proteins, Biophys. J, 93, 1442-1451 (2007). E. J. Smith, T. Bryk and A. D. J. Haymet, Reply to “Comment on Molecular dynamics study of solvation of Cl (Washington, DC, U. S.), 47, 6245-6253 (2008). Patrick L. Feng, Changhyun Koo, John J. Henderson, Motohiro Nakano, Stephen Hill, Enrique del Barco and David N. Hendrickson, Single-Molecule-Magnet Behavior and Spin Changes Affected by Crystal Packing Effects, Inorg. Chem. (Washington, DC, U. S.), 47, 8610-8612 (2008). Sonali J. Shah, Christopher M. Ramsey, Katie J. Heroux, Antonio G. DiPasquale, Naresh S. Dalal, Arnold L. Rhein- gold, Enrique del Barco and David N. Hendrickson, Molecu- lar Wheels: New Mn12 Complexes as Single-Molecule Magnets, Inorg. Chem. (Washington, DC, U. S.), 47, 9569-9582 diazin-3’-yl)-5-hydroxy-2H-pyridazin-3-ones. Part 2: Variation of the 2- and 6-pyridazinone substituents, Bioorg. Med. Chem. Lett, 18, 1419-1424 (2008). Yuefen Zhou, Chun Chow, Douglas E. Murphy, Zhongxiang Sun, Thomas Bertolini, Jamie M. Froelich, Stephen E. Webber, Thomas Hermann and Daniel Wall, Antibacterial activity in serum of the 3,5-diamino-piperidine translation inhibitors, Bioorg. Med. Chem. Lett, 18, 3369-3375 (2008). HOFFMANN, ALEXANDER (b.1966) Assistant - and Na (2008). Professor. B.A, 1988, Cambridge University; M.Ph, + in the ice/water interface’ [J. Chem. Phys. 123, 034706 (2005)], J. Chem. Phys, 126, 237102/1-237102/2 (2007). P. W. Wilson and A. D. J. Haymet, Workman-Reynolds Freezing Potential Measurements between Ice and Dilute Salt Solutions for Single Ice Crystal Faces, J. Phys. Chem. B, 112, 11750-11755 (2008). P. W. Wilson and A. D. J. Haymet, Comment on “Workman-Reynolds Freezing Potential Measurements between Ice and Dilute Salt Solutions for Single Ice Crystal Faces, J. Phys. Chem. B, 112, 15260 (2008). HENDRICKSON, DAVID N. (b.1943) Professor. B.S, 1966, University of California, L.A; Ph.D, 1969, University of California, Berkeley. Fellowship, 1970, California Institute of Technology. Inorganic Chemistry; Nanochemistry. Magnetic bistability in single-molecule magnets; resonant magnetization quantum tunneling; dynamics in transition metal complexes; optical bistability in valence tautomeric and spin-crossover complexes; magnetic exchange in polynuclear complexes. TEL: (858) 534-5580 FAX: (858) 534-5383 Email: dhendrickson@ucsd.edu Ai-Ju Zhou, Lian-Jing Qin, Christopher C. Beedle, Shu Emi Evangelio, David N. Hendrickson and Daniel Ruiz- Molina, Intramolecular electron transfer in the mixed-valence [Co(3,5-DTBCat)(3,5-DTBSQ)(bpy)] complex: Beyond valence tautomerism, Inorg. Chim. Acta, 361, 3403-3409 (2008). Patrick L. Feng, Christopher C. Beedle, Changhyun Koo, Jon Lawrence, Stephen Hill and David N. Hendrickson, Origin of magnetization tunneling in single-molecule magnets as determined by single-crystal high-frequency EPR, Inorg. Chim. Acta, 361, 3465-3480 (2008). Michio Sorai, Ramon Burriel, Edgar F. Westrum, Jr. and David N. Hendrickson, Mechanochemical Effect in the Iron (III) Spin Crossover Complex [Fe(3-MeO-salenEt)2]PF6 as Studied by Heat Capacity Calorimetry, J. Phys. Chem. B, 112, 4344-4350 (2008). Christopher M. Ramsey, Enrique del Barco, Stephen Hill, Sonali J. Shah, Christopher C. Beedle and David N. Hendrickson, Quantum interference of tunnel trajectories between states of different spin length in a dimeric molecular nanomagnet, Nat. Phys, 4, 277-281 (2008). Sonali J. Shah, Single-molecule magnets: Polynuclear manganese wheels and clusters. (D) 1991, Cambridge University; Ph.D, 1994, Rockefeller University. Postdoctoral Associate, 1995-1998, M. I. T; Postdoctoral Associate, 1998-2003, CalTech. Biochemis- try. Eukaryotic gene expression is regulated by a circuitry of signaling pathways. My research is focused on NFkB signaling that controls mammalian immune and stress responses. Using computational modeling, I aim to con- nect biochemical results from in vitro studies and from genetically altered cells and mice. Constructing a computational model of this signaling pathway leads to quantitative understanding, novel hypotheses, and exploration of novel therapeutic agents for a host of human diseases. TEL: (858) 822-0212 FAX: (858) 534-6693 Web: www-chem.ucsd.edu/research/profile.cfm?cid= C04518 Email: ahoffmann@ucsd.edu Alexander Hoffmann, Yifeng Xia and Inder M. Verma, In- flammatory tales of liver cancer, Cancer Cell, 11, 99-101 (2007). Soumen Basak, Hana Kim, Jeffrey D. Kearns, Vinay Tergaonkar, Ellen O’Dea, Shannon L. Werner, Chris A. Bened- ict, Carl F. Ware, Gourisankar Ghosh, Inder M. Verma and Ding, Motohiro Nakano, Ji-Dong Leng, Ming-Liang Tong and David N. Hendrickson, New Mn12 Clusters with Tunable Oxidation States via the Use of N,N,N’,N’-Tetrakis(2-hy- HERMANN, THOMAS Assistant Professor. B.S, 1988, University of Ulm, Germany; M.S, 1992, Univer- Alexander Hoffmann, A fourth I�B protein within the NF-�B signaling module, Cell (Cambridge, MA, U. S.), 128, 369- 381 (2007).
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