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16 CALIFORNIA, SAN DIEGO sistor and interdigitated electrode chemical sensors based on metallophthalocyanines. Use of hollow porous silica and titania nanoparticles in drug and gene delivery. TEL: (858) 534-6175 FAX: (858) 534-5383 Web: www-chem.ucsd.edu/research/profile.cfm?cid= C02165 Email: wtrogler@ucsd.edu Richard D. Yang, T. Gredig, Corneliu N. Colesniuc, Jenase D Revealed by a Genetically Encoded Kinase Activity Reporter, J. Biol. Chem, 282, 6733-6742 (2007). Oded Tour, Stephen R. Adams, Rex A. Kerr, Rene M. Meijer, Terrence J. Sejnowski, Richard W. Tsien and Roger Y. Tsien, Calcium Green FlAsH as a genetically targeted smallmolecule calcium indicator, Nat. Chem. Biol, 3, 423-431 (2007). Christina T. Hauser and Roger Y. Tsien, A hexahistidine- Zn live cells and in vivo. Study the origin and evolution of the genetic code using genetic engineering and synthetic biology methods. TEL: (858) 453-4100 FAX: (858) 597- 0855 Web: wang.salk.edu Email: lwang@salk.edu L. Wang and P. G. Schultz, Expanding the genetic code, Angewandte Chemie International Edition, 44, 34-66 (2005). 2+-dye ongwon Park, Ivan K. Schuller, William C. Trogler and Andrew C. Kummel, Ultrathin organic transistors for chemical sensing, Appl. Phys. Lett, 90, 263506/1-263506/3 (2007). Jason C. Sanchez, Antonio G. DiPasquale, Arnold L. Rheingold and William C. Trogler, Synthesis, Luminescence Properties, and Explosives Sensing with 1,1-Tetraphenylsilole- and 1,1-Silafluorene-vinylene Polymers, Chem. Mater, 19, 6459-6470 (2007). Forest I. Bohrer, Amos Sharoni, Corneliu Colesniuc, Jeongwon Park, Ivan K. Schuller, Andrew C. Kummel and label reveals STIM1 surface exposure, Proc. Natl. Acad. Sci. U. S. A, 104, 3693-3697 (2007). Nathan C. Shaner, Michael Z. Lin, Michael R. McKeown, Paul A. Steinbach, Kristin L. Hazelwood, Michael W. Davidson and Roger Y. Tsien, Improving the photostability of bright monomeric orange and red fluorescent proteins, Nat. Methods, 5, 545-551 (2008). Damian J. Wallace, Stephan Meyer zum Alten Borgloh, Simone Astori, Ying Yang, Melanie Bausen, Sebastian Kue- gler, Amy E. Palmer, Roger Y. Tsien, Rolf Sprengel, Jason N. D. Kerr, Winfried Denk and Mazahir T. Hasan, Single- spike detection in vitro and in vivo with a genetic Ca Y. Zhang, L. Wang, P. G. Schultz and I. A. Wilson, Crys- tal structures of apo Wild-Type M. jannaschii TyrRS and a mutant synthetase specific for O-Methyl-L-Tyrosine, Protein Science, 14, 1340-1349 (2005). L. Wang, J. Xie and P. G. Schultz, Exanding the genetic code, Annual Review of Biophysics and Biomolecular Structure, 35, 225-249 (2006). A. R. Parrish, W. Wang and L. Wang, Manipulating proteins for neuroscience, Current Opinion in Neurobiology, 16, 585-592 (2006). L. Wang and R. Y. Tsien, Evolving proteins in mammalian 2+ William C. Trogler, Gas Sensing Mechanism in Chemiresis- tive Cobalt and Metal-Free Phthalocyanine Thin Films, J. Am. Chem. Soc, 129, 5640-5646 (2007). Richard D. Yang, Jeongwon Park, Corneliu N. Colesniuc, Ivan K. Schuller, William C. Trogler and Andrew C. Kum- mel, Ultralow drift in organic thin-film transistor chemical sensors by pulsed gating, J. Appl. Phys, 102, 034515/1- 034515/7 (2007). Sarah J. Toal, Jason C. Sanchez, Regina E. Dugan and William C. Trogler, Visual detection of trace nitroaromatic explosive residue using photoluminescent metallole-containing polymers, J. Forensic Sci, 52, 79-83 (2007). Sarah L. Blair, Jessica Wang-Rodriguez, Maria J. Cortes, Davorka Messmer, Andrew C. Kummel and William C. Trogler, Enhanced touch preps to improve the ease of interpretation of intra-operative breast cancer margins, The American Surgeon, 73, 973-976 (2007). Jeongwon Park, Richard D. Yang, Corneliu N. Colesniuc, Amos Sharoni, Sungho Jin, Ivan K. Schuller, William C. Trogler and Andrew C. Kummel, Bilayer processing for an enhanced organic-electrode contact in ultrathin bottom contact organic transistors, Appl. Phys. Lett, 92, 193311/1- 193311/3 (2008). Jian Yang, Johan U. Lind and William C. Trogler, Synthesis of Hollow Silica and Titania Nanospheres, Chem. Mater, 20, 2875-2877 (2008). Forest I. Bohrer, Corneliu N. Colesniuc, Jeongwon Park, Ivan K. Schuller, Andrew C. Kummel and William C. Trogler, Selective Detection of Vapor Phase Hydrogen Peroxide with Phthalocyanine Chemiresistors, J. Am. Chem. Soc, 130, 3712-3713 (2008). Jason C. Sanchez and William C. Trogler, Efficient blueemitting silafluorene-fluorene-conjugated copolymers: selective turn-off/turn-on detection of explosives, J. Mater. Chem, 18, 3143-3156 (2008). Jason C. Sanchez and William C. Trogler, Hydrosilylation of diynes as a route to functional polymers delocalized through silicon, Macromol. Chem. Phys, 209, 1527-1540 (2008). Jason C. Sanchez, Sara A. Urbas, Sarah J. Toal, Antonio G. DiPasquale, Arnold L. Rheingold and William C. Trogler, Catalytic Hydrosilylation Routes to Divinylbenzene Bridged Silole and Silafluorene Polymers. Applications to Surface Imaging of Explosive Particulates, Macromolecules (Washington, DC, U. S.), 41, 1237-1245 (2008). sensor, Nat. Methods, 5, 797-804 (2008). Stephen R. Adams and Roger Y. Tsien, Preparation of the membrane-permeant biarsenicals FlAsH-EDT2 and ReAsH- EDT2 for fluorescent labeling of tetracysteine-tagged proteins, Nat. Protoc, 3, 1527-1534 (2008). Samuel Andrew Hires, Yongling Zhu and Roger Y. Tsien, Optical measurement of synaptic glutamate spillover and reuptake by linker optimized glutamate-sensitive fluorescent reporters, Proc. Natl. Acad. Sci. U. S. A, 105, 4411-4416 (2008). Michael Z. Lin, Jeffrey S. Glenn and Roger Y. Tsien, A drug-controllable tag for visualizing newly synthesized proteins in cells and whole animals, Proc. Natl. Acad. Sci. U. S. A, 105, 7744-7749 (2008). Emilia Olson, Detecting pathological protease activity with activatable cell penetrating peptides (ACPP’s). (D) TUKEY, ROBERT H. (b.1949) Professor. B.Sc, 1973, University of Minnesota; Ph.D, 1980, University of Iowa. Pharmacology. Environmental toxicology: The role of environmental and chemical toxicants on gene expression. TEL: (858) 822-0288 FAX: (858) 822-0363 Web: superfund.ucsd.edu/ Email: rtukey@ucsd.edu Kathy Senekeo-Effenberger, Shujuan Chen, Erin Brace- Sinnokrak, Jessica A. Bonzo, Mei-Fei Yueh, Upendra Argi- kar, Jenny Kaeding, Jocelyn Trottier, Rory P. Remmel, Jo- seph K. Ritter, Olivier Barbier and Robert H. Tukey, Expression of the human UGT1 locus in transgenic mice by 4-chloro-6-(2,3-xylidino)-2-pyrimidinylthioacetic acid (WY-14643) and implications on drug metabolism through peroxisome proliferator-activated receptor � activation, Drug Metab. Dispos, 35, 419-427 (2007). Jessica A. Bonzo, Alain Belanger and Robert H. Tukey, The role of chrysin and the Ah receptor in induction of the human UGT1A1 gene in vitro and in transgenic UGT1 mice, Hepatology (Hoboken, NJ, U. S.), 45, 349-360 (2007). Theresa N. Operana and Robert H. Tukey, Oligomerization of the UDP-glucuronosyltransferase 1A Proteins: Homo- and heterodimerization analysis by fluorescence resonance energy transfer and co-immunoprecipitation, J. Biol. Chem, 282, 4821-4829 (2007). Mei-Fei Yueh and Robert H. Tukey, Nrf2-Keap1 Signaling cells using somatic hypermutation, Nature Protocols, 1, 1346-1350 (2006). W. Wang, J. K. Takimoto, G. V. Louie, T. J. Baiga, J. P. Noel, K.-F. Lee, P. A. Slesinger and L. Wang, Genetically encoding unnatural amino acids for cellular and neuronal studies, Nature Neuroscience, 10, 1063-1072 (2007). D. B. F. Johnson, J. K. Takimoto, J. Xu and L. Wang, Unnatural amino acids to investigate biological processes, Wiley Encyclopedia of Chemical Biology, doi:10.1002/ 9780470048672 (2007). Q. Wang and L. Wang, New methods enabling efficient incorporation of unnatural amino acids in yeast, Journal of the American Chemical Society, 130, 6066-6067 (2008). M. Z. Lin and L. Wang, Selective labeling of proteins with chemical probes in living cells, Physiology, 23, 131-141 (2008). WANG, WEI Associate Professor. Postdoctoral Fellow, 2001-2003, Stanoford University. Bioinformatics; Computational Chemistry. TEL: (858) 822-4240 FAX: (858) 822-4236 Web: wanglab.ucsd.edu Email: wei-wang@ucsd.edu No publication information submitted for this edition. WATSON, JOSEPH W. No publication information submitted for this edition. WEARE, JOHN H. (b.1940) Professor. B.S, 1962, Harvey Mudd College; Ph.D, 1968, The Johns Hopkins University. AFOSR Fellowship, 1968-1969, M.I.T; Gug- genheim Fellowship, 1976-1977, Harvard University. Theoretical chemistry; ab initio molecular dynamics; theory of clusters, surfaces, and condensed matter; theory of geochemical processes. TEL: (858) 534-3286 FAX: (858) 534-7244 Web: www.chem.ucsd.edu/Faculty/Research_text/ weare.html Email: jweare@ucsd Publication list has not been verified by the department. Eric J. Bylaska, Marat Valiev, James R. Rustad and John H. Weare, Structure and dynamics of the hydration shells of the Al3+ Forest I. Bohrer, Gas sensing mechanisms in chemiresistive metal phthalocyanine nanofilms. (D) Jason C. Sanchez, Design and optimization of polymeric silole and boronate photoluminescent probes for improved Pathway Regulates Human UGT1A1 Expression in Vitro and in Transgenic UGT1 Mice, J. Biol. Chem, 282, 8749-8758 (2007). Theresa N. Operana, Nghia Nguyen, Shujuan Chen, Deirdre Beaton and Robert H. Tukey, Human CYP1A1 ion, J. Chem. Phys, 126, 104505/1-104505/8 (2007). Marat Valiev, Jie Yang, Joseph A. Adams, Susan S. Taylor and John H. Weare, Phosphorylation Reaction in cAPK Pro- tein Kinase-Free Energy Quantum Mechanical/Molecular Mechanics Simulations, J. Phys. Chem. B, 111, 13455-13464 GFP explosives detection applications. (D) Expression in Transgenic Mice Serves as a Biomarker for Envi- (2007). TSIEN, ROGER Y. (b.1952) Professor. A.B, 1972, Harvard; Ph.D, 1977, University of Cambridge, Cambridge, UK. Comyns Berkeley Research Fellowship, 1977-1981, Gonville & Caius College, Cambridge, U.K. Design, synth. and use of fluorescent indicators and photoreleasable messengers to probe intracellular signs such as Ca, inositol phosphates, cyclic nucleotides and nitric oxide; eng. of Green Fluorescent Protein; pharma’l ultrahigh-throughput screening. TEL: (858) 534-4891 FAX: (858) 534-5270 Web: www.tsienlab.ucsd.edu Email: rtsien@ucsd.edu Hui-Wang Ai, Nathan C. Shaner, Zihao Cheng, Roger Y. Tsien and Robert E. Campbell, Exploration of New Chromophore Structures Leads to the Identification of Improved Blue Fluorescent Proteins, Biochemistry, 46, 5904-5910 (2007). Brent R. Martin, Thomas J. Deerinck, Mark H. Ellisman, Susan S. Taylor and Roger Y. Tsien, Isoform-Specific PKA Dynamics Revealed by Dye-Triggered Aggregation and DA- KAP1�-Mediated Localization in Living Cells, Chem. Biol. (Cambridge, MA, U. S.), 14, 1031-1042 (2007). Stephen R. Adams and Roger Y. Tsien, Imaging the influx of cell-penetrating peptides into the cytosol of individual live cells, Handb. Cell-Penetrating Pept. (2nd Ed.), 505-513 (2007). Maya T. Kunkel, Alex Toker, Roger Y. Tsien and Alexandra C. Newton, Calcium-dependent Regulation of Protein Kironmental Toxicant Exposure, Toxicol. Sci, 95, 98-107 (2007). Nghia Nguyen, Jessica A. Bonzo, Shujuan Chen, Sarah Chouinard, Michael J. Kelner, Gary Hardiman, Alain Belan- ger and Robert H. Tukey, Disruption of the Ugt1 Locus in Mice Resembles Human Crigler-Najjar Type I Disease, J. Biol. Chem, 283, 7901-7911 (2008). Sarah Chouinard, Mei-Fei Yueh, Robert H. Tukey, Frank Giton, Jean Fiet, Georges Pelletier, Olivier Barbier and Alain Belanger, Inactivation by UDP-glucuronosyltransferase enzymes: The end of androgen signaling, J. Steroid Biochem. Mol. Biol, 109, 247-253 (2008). VIADIU, HECTOR Assistant Professor. TEL: (858) 822-4486 FAX: (858) 822-4499 Web: www-chem.ucsd.edu/research/profile.cfm?cid= C20803 Email: viadiu@ucsd.edu Publication list has not been verified by the department. Hector Viadiu, Tamir Gonen and Thomas Walz, Projection Map of Aquaporin-9 at 7 Å Resolution, J. Mol. Biol, 367, 80- 88 (2007). WANG, LEI (b.1972) Assistant Professor. B.S, 1994, Peking University; Ph.D, 2002, University of California at Berkeley. Merck Fellow of the Damon Runyon Cancer Research Foundation, 2002-2005, University of California, San Diego. Chemical Biology. Genetically encoding novel amino acids to investigate biological processes in WEINBERGER, LEOR S. Assistant Professor. Ph.D, 2004, UC Berkeley. Lewis Thomas Fellow, 2005-2007, Princeton University. Biochemistry. TEL: (858) 534- 8671 FAX: (858) 246-0864 Web: weinbergerlab.ucsd.edu Email: lsw@ucsd.edu Leor S. Weinberger and Thomas Shenk, An HIV feedback resistor: Auto-regulatory circuit deactivator and noise buffer, Los Alamos Natl. Lab., Prepr. Arch., Quant. Biol, 1-15 (2007). Leor S. Weinberger and Thomas Shenk, An HIV feedback resistor: Auto-regulatory circuit deactivator and noise buffer, PLoS Biol, 5, 67-81 (2007). Leor S. Weinberger, Roy D. Dar and Michael L. Simpson, Transient-mediated fate determination in a transcriptional circuit of HIV, Nat. Genet, 40, 466-470 (2008). WEIZMAN, HAIM (b.1965) LPSOE. B.Sc, 1992, The Hebrew University of Jerusalem; M.S, 1994, The Weizmann Institute of Science; Ph.D, 1999, The Weizmann Institute of Science. Postdoctoral research fellow, 1999- 2003, University of California, San Diego; Project Scientist, 2003-2005, University of California, San Diego; Lecturer, 2003-2005, University of California, San Diego. Organic Chemistry. Chemical education: representa- tions, development of curriculum for organic and bioor- ganic chemistry, and cognitive process related to teaching of chemistry. TEL: (858) 534-2963 FAX: (858) 534- 0202
CALIFORNIA, SAN DIEGO 17 Web: www-chem.ucsd.edu/research/profile.cfm?cid= C03537 Email: hweizman@ucsd.edu K. C. Nguyen and H. Weizman, Greening Wittig reactions: Solvent –free synthesis of Ethyl trans-Cinnamate and E-3-(9- Anthryl)-2-Propenoic Acid Ethyl Ester, J. Chem. Ed, 84, 119-121 (2007). R. Hwa and H. Weizman, Revisiting the separation of Ferrocene and Acetylferrocene by adsorption chromatography: Adding a third component, J. Chem. Ed, 84, 1497-1498 (2007). Y. Tor, S. Del Valle, D. Jaramillo, S. G. Srivatsan and H. Weizman, Designing new isomorphic fluorescent nucleobase analogues: The thieno[3,2-d]pyrimidine core, Tetrahedron, 63, 3608-3614 (2007). H. Weizman, Why are D. Schultz, E. Ben Jacob, J. N. Onuchic and P. G. Wolynes, Molecular level stochastic model for competence cycles in Bacillus subtilis, PNAS, 104, 17582-17587 (2007). T. Lu, T. Shen, M. Bennett, P. G. Wolynes and J. Hasty, Phenotypic variability of growing cellular populations, PNAS, 104, 18982-18987 (2007). D. Ferreiro, J. Hegler, E. Komives and P. G. Wolynes, Localizing frustration in native proteins and protein assemblies, PNAS, 104, 19819-19824 (2007). L. Sutto, J. Latzer, J. Hegler, D. Ferreiro and P. G. Wolynes, Consequences of localized frustration for the folding mechanism of the IM7 protein, PNAS, 104, 19825-19830 (2007). C. Zong, C. J. Wilson, T. Shen, P. Wittung-Staffshede, S. Mayo and P. Wolynes, Establishing the entatic state in folding metallated pseudomonas aeruginosa azurin, PNAS, 104, and contextual or ecology data, the role of microbes in the environment and the impact of environments on mi- crobial communities. TEL: (858) 534-2494 FAX: (858) 822-1452 Web: www-chem.ucsd.edu/research/profile.cfm?cid= C03721 Email: jwooley@ucsd.edu Y. Ye and J. Wooley, A historical perspective and overview of protein structure prediction, Computational Methods for Protein Structure Prediction and Modeling, (2007). Chloe Zubieta, S. Sri Krishna, Mili Kapoor, Piotr Kozbial, Daniel McMullan, Herbert L. Axelrod, Mitchell D. Miller, Polat Abdubek, Eileen Ambing, Tamara Astakhova, Dennis Carlton, Hsiu-Ju Chiu, Thomas Clayton, Marc C. Deller, Lian Duan, Marc-Andre Elsliger, Julie Feuerhelm, Slawomir 1H NMR integrations not perfect? An inquiry based exercise for exploring the relationship between spin-dynamics and NMR integration in the organic laboratory, J. Chem. Ed, 85, 294-296 (2008). S. G. Srivatsan, H. W. Weizman and H. Y. Tor, A highly fluorescent nucleoside analog based on thieno[3,4-d]pyrimidine senses mismatched pairing, Org. Biomol. Chem, 6, 1334—1338 (2008). WENKERT, ERNEST (b.1925) Professor Emeritus. B.S, 1945, University of Washington; M.S, 1947, University of Washington; Ph.D, 1951, Harvard University. Synthesis and structure analysis of organic natural products; development of new methods of organochemical synthesis; synthesis based on transition metal-mediated reactions. TEL: (619) 534-4942 FAX: (858) 534-4864 Email: ewenkert@ucsd.edu No publication information submitted for this edition. WHEELER, JOHN C. (b.1941) Professor. B.A, 1963, Oberlin College; Ph.D, 1968, Cornell University. NSF Fellowship, 1967-1969, Harvard University; Alfred P. Sloan Foundation Fellowship, 1972-1976, University of California, San Diego; Guggenheim Foundation Fellowship, 1983-1984, Université de Paris-Sud Centre d’Orsay. Theoretical chemistry: statistical mechanics, thermodynamics; phase transitions, critical phenomena in mixtures; moment analysis of spectral densities. Polymers and polymerization. Vibrational motion at solid surfaces. Phase equilibria in micellar solutions. TEL: (858) 534-3287 FAX: (858) 534-7244 Web: www.chem.ucsd.edu/Faculty/Research_text/ wheeler.html Email: jwheeler@ucsd.edu No publication information submitted for this edition. WHITESELL, JAMES K. (b.1944) Professor. B.S, 1966, Pennsylvania State University; Ph.D, 1971, Harvard University. Postdoctoral, 1971-1973, Woodward Research Institute. Organic Chemistry. Stereochemistry, both in a molecular and a supramolecular sense. Solar energy harvesting. Materials for photonic applications. TEL: (858) 534-5870 FAX: (858) 534-5383 Email: jkw@ucsd.edu No publication information submitted for this edition. WOLYNES, PETER GUY (b.1953) Francis H. C. Crick Professor. A.B, 1971, Indiana University; A.M, 1972, Harvard University; Ph.D, 1976, Harvard University; D.Sc, 1988, Indiana University. Research Associate, 1975-1976, M. I. T. Biophysics/Biophysical Chemistry; Physical Chemistry. Protein folding and function; glasses; dynamics of biomolecules; stochastic cell biology; theoretical chemical physics. TEL: (858) 822-4825 FAX: (858) 822-4560 Web: www.chem.ucsd.edu/Faculty/bios/wolynes.html Email: pwolynes@ucsd.edu V. Lubchenko, R. J. Silbey and P. G. Wolynes, The microscopic quantum theory of low temperature amorphous solids, Adv. Chem. Phys, 136, 95-206 (2007). V. Lubchenko and P. G. Wolynes, Theory of structural 3159-3164 (2007). P. G. Wolynes, Lectures on biomolecular energy landscapes, Proceedings of the International School of Physics “Enrico Fermi” Course CLXV, 27-46 (2007). J. Latzer, T. Shen and P. Wolynes, Conformational switching upon phosphorylation: A predictive framework based on energy landscape principles, Biochem, 47, 2110-2122 (2008). L. S. Itzhaki and P. G. Wolynes, The quest to understand protein folding, Curr. Op. Struct. Bio, 18, 1-3 (2008). J. A. Hegler, P. Weinkam and P. G. Wolynes, The spectrum of biomolecular states and motions, HFSP Journal, 2, 307-313 (2008). P. G. Whitford, J. N. Onuchic and P. G. Wolynes, The energy landscape along an enzymatic reaction trajectory: Hinges or cracks?, HFSP Journal, 2, 61-64 (2008). J. D. Stevenson, A. M. Walczak, R. W. Hall and P. G. Wolynes, Constructing explicit magnetic analogies for the dynamics of glass forming liquids, J. Chem. Phys, 129, 194505-1-6 (2008). M. C. Prentiss, D. J. Wales and P. G. Wolynes, Protein structure prediction using basin hopping, J. Chem. Phys, 128, 225106-1-9 (2008). J. D. Stevenson and P. G. Wolynes, On the surface of glasses, J. Chem. Phys, 129, 234514-1-4 (2008). T. Shen, C. Zong, J. Portman and P. G. Wolynes, Variationally determined free energy profiles for structural models of proteins: Characteristic temperatures for folding and trapping, J. Phys. Chem .B, 112, 6074-6082 (2008). R. W. Hall and P. G. Wolynes, Intermolecular forces and the glass transition, J. Phys. Chem. B, 112, 301-312 (2008). P. G. Wolynes, Protein folding and beyond: Energy landscapes and the organization of living matter in space and time, Physical Biology from Atoms to Medicine, 267-288 (2008). D. U. Ferreiro, A. M. Walczak, E. A. Komives and P. G. Wolynes, The energy landscapes of repeat-containing proteins: Topology, cooperativity and the folding funnels of onedimensional architectures, PLOS Computational Biology, 4, 1-12 (2008). S. Bhattacharyya, B. Bagchi and P. G. Wolynes, Facilitation, complexity growth, mode coupling and activated dynamics in supercooled liquids, PNAS, 105, 16067-16082 (2008). D. Schultz, A. M. Walczak, J. N. Onuchic and P. G. Wol- ynes, Extinction and resurrection in gene networks, PNAS, 105, 19165-19170 (2008). D. U. Ferreiro and P. G. Wolynes, The capillarity picture and the kinetics of one-dimensional protein folding, PNAS, 105, 9853-9854 (2008). P. G. Wolynes, The protein folding energy landscape: A primer, Protein Folding, Misfolding and Aggregation, 49-69 (2008). Aleksandra Walczak, Many body theory of stochastic gene networks. (D) Chenghang Zong, Theoretical studies of biomolecular self- assembly near equilibrium and far from equilibrium. (D) Joachim Laetzer, Computational tools based on energy landscape theory to predict structurally diverse ensembles of transcription factors. (D) Samuel S. Cho, Energy landscapes for protein folding, binding, and aggregation: Simple funnels and beyond. (D) Ting Lu, Stochasticity in biological networks: Two sides of a golden coin. (D) K. Grzechnik, Joanna Hale, Eric Hampton, Gye Won Han, Lukasz Jaroszewski, Kevin K. Jin, Heath E. Klock, Mark W. Knuth, Abhinav Kumar, David Marciano, Andrew T. Morse, Edward Nigoghossian, Linda Okach, Silvya Oommachen, Ron Reyes, Christopher L. Rife, Paul Schimmel, Henry van den Bedem, Dana Weekes, Aprilfawn White, Qingping Xu, Keith O. Hodgson, John Wooley, Ashley M. Deacon, Adam Godzik, Scott A. Lesley and Ian A. Wilson, Crystal structures of two novel dye-decolorizing peroxidases reveal a �- barrel fold with a conserved heme-binding motif, Proteins: Struct., Funct., Bioinf, 69, 223-233 (2007). Chloe Zubieta, Rosanne Joseph, S. Sri Krishna, Daniel McMullan, Mili Kapoor, Herbert L. Axelrod, Mitchell D. Miller, Polat Abdubek, Claire Acosta, Tamara Astakhova, Dennis Carlton, Hsiu-Ju Chiu, Thomas Clayton, Marc C. Deller, Lian Duan, Ylva Elias, Marc-Andre Elsliger, Julie Feuerhelm, Slawomir K. Grzechnik, Joanna Hale, Gye Won Han, Lukasz Jaroszewski, Kevin K. Jin, Heath E. Klock, Mark W. Knuth, Piotr Kozbial, Abhinav Kumar, David Marciano, Andrew T. Morse, Kevin D. Murphy, Edward Nigoghossian, Linda Okach, Silvya Oommachen, Ron Reyes, Christopher L. Rife, Paul Schimmel, Christina V. Trout, Henry van den Bedem, Dana Weekes, Aprilfawn White, Qingping Xu, Keith O. Hodgson, John Wooley, Ashley M. Deacon, Adam Godzik, Scott A. Lesley and Ian A. Wilson, Identification and structural characterization of heme binding in a novel dye-decolorizing peroxidase, TyrA, Proteins: Struct., Funct., Bioinf, 69, 234-243 (2007). Dana Weekes, Mitchell D. Miller, S. Sri Krishna, Daniel McMullan, Timothy M. McPhillips, Claire Acosta, Jaume M. Canaves, Marc-Andre Elsliger, Ross Floyd, Slawomir K. Grzechnik, Lukasz Jaroszewski, Heath E. Klock, Eric Koese- ma, John S. Kovarik, Andreas Kreusch, Andrew T. Morse, Kevin Quijano, Glen Spraggon, Henry van den Bedem, Guenter Wolf, Keith O. Hodgson, John Wooley, Ashley M. Deacon, Adam Godzik, Scott A. Lesley and Ian A. Wilson, Crystal structure of a transcription regulator (TM1602) from Thermotoga maritima at 2.3 Å resolution, Proteins: Struct., Funct., Bioinf, 67, 247-252 (2007). S. Sri Krishna, Lutz Tautz, Qingping Xu, Daniel McMullan, Mitchell D. Miller, Polat Abdubek, Eileen Ambing, Ta- mara Astakhova, Herbert L. Axelrod, Dennis Carlton, Hsiu- Ju Chiu, Thomas Clayton, Michael DiDonato, Lian Duan, Marc-Andre Elsliger, Slawomir K. Grzechnik, Joanna Hale, Eric Hampton, Gye Won Han, Justin Haugen, Lukasz Jaroszewski, Kevin K. Jin, Heath E. Klock, Mark W. Knuth, Eric Koesema, Andrew T. Morse, Tomas Mustelin, Edward Ni- goghossian, Silvya Oommachen, Ron Reyes, Christopher L. Rife, Henry van den Bedem, Dana Weekes, Aprilfawn White, Keith O. Hodgson, John Wooley, Ashley M. Deacon, Adam Godzik, Scott A. Lesley and Ian A. Wilson, Crystal structure of NMA 1982 from Neisseria meningitidis at 1.5 Å resolution provides a structural scaffold for nonclassical, eukaryotic-like phosphatases, Proteins: Struct., Funct., Bioinf, 69, 415-421 (2007). Qingping Xu, Kumar Singh Saikatendu, S. Sri Krishna, Daniel McMullan, Polat Abdubek, Sanjay Agarwalla, Eileen Ambing, Tamara Astakhova, Herbert L. Axelrod, Dennis Carlton, Hsiu-Ju Chiu, Thomas Clayton, Michael DiDonato, Lian Duan, Marc-Andre Elsliger, Julie Feuerhelm, Slawomir K. Grzechnik, Joanna Hale, Eric Hampton, Gye Won Han, Justin Haugen, Lukasz Jaroszewski, Kevin K. Jin, Heath E. Klock, Mark W. Knuth, Eric Koesema, Mitchell D. Miller, Andrew T. Morse, Edward Nigoghossian, Linda Okach, Silvglasses and supercooled liquids, Ann. Rev. Phys. Chem, 58, 235-266 (2007). D. U. Ferreiro, C. F. Cervantes, M. E. Truhlar, S. S. Cho, P. G. Wolynes and E. A. Komives, Stabilizing IkBk by “consensus” design, J. Mol. Bio, 365, 1201-1216 (2007). J. Latzer, G. Papoian, M. Prentiss, E. Komives and P. G. WOOLEY, JOHN (b.1945) Professor. B.S, 1967, Michigan State University; Ph.D, 1975, The University of Chicago. Research Fellow/ Postdoc, 1975, G. D. Searle Pharmaceuticals, Ltd; research associate/Postdoc, 1976-1977, Harvard University Dept of Biochemical ya Oommachen, Jessica Paulsen, Ron Reyes, Christopher L. Rife, Robert Schwarzenbacher, Henry van den Bedem, Aprilfawn White, Guenter Wolf, Keith O. Hodgson, John Wooley, Ashley M. Deacon, Adam Godzik, Scott A. Lesley and Ian A. Wilson, Crystal structure of MtnX phosphatase from Bacillus subtilis at 2.0 Å resolution provides a structural basis Wolynes, Induced fit, folding, and recognition of the NF-kBnuclear localization signals by IkBa and IdBb, J. Mol. Bio, 376, 262-274 (2007). D. Schultz, J. N. Onuchic and P. G. Wolynes, Understanding stochastic simulations of the smallest genetic networks, J. Phys. Chem, 126, 245102-1-11 (2007). Y. Levy, J. N. Onuchic and P. G. Wolynes, Fly-casting in Protein-DNA binding: Frustration between protein folding and electrostatics facilitates target recognition, JACS, 3, 738- 739 (2007). M. Gruebele and P. G. Wolynes, Quantizing ULam’s control conjecture, Phys. Rev. Lett, 99, 060201-1-4 (2007). S. S. Cho, P. Weinkam and P. G. Wolynes, Origins of barriers and barrierless folding in BBL, PNAS, 104, 112-123 (2007). Sciences; Physiology Course Instructor, 1978, Marine Biological Labs; Assistant Professor, 1978-1983, Princeton University/ Dept of Biology and Dept of Biochemical Sciences; Program Director, 1984-1988, NSF Biological Instrumentation Program; Division Director, 1988- 1992, NSF Instrumentaion and Resources Division; Deputy Associate Director, 1992-1999, DOE Biological and Environmental Research; Associate VC of Research, 1999-2008, UC San Diego. Bioinformatics; Structural Biology. In structural genomics, the research focuses on obtaining insight, by way of experimental and computational studies on protein structures, into the protein universe. In metagenomics, the research focuses on charac- terizing, by way of coupled analysis of sequence data for bipartite phosphomonoester hydrolysis of 2-hydroxy-3keto-5-methylthiopentenyl-1-phosphate, Proteins: Struct., Funct., Bioinf, 69, 433-439 (2007). Irimpan I. Mathews, Daniel McMullan, Mitchell D. Miller, Jaume M. Canaves, Marc-Andre Elsliger, Ross Floyd, Sla- womir K. Grzechnik, Lukasz Jaroszewski, Heath E. Klock, Eric Koesema, John S. Kovarik, Andreas Kreusch, Peter Kuhn, Timothy M. McPhillips, Andrew T. Morse, Kevin Quijano, Christopher L. Rife, Robert Schwarzenbacher, Glen Spraggon, Raymond C. Stevens, Henry van den Bedem, Dana Weekes, Guenter Wolf, Keith O. Hodgson, John Woo- ley, Ashley M. Deacon, Adam Godzik, Scott A. Lesley and Ian A. Wilson, Crystal structure of 2-keto-3-deoxygluconate kinase (TM0067) from Thermotoga maritima at 2.05 Å resolution, Proteins: Struct., Funct., Bioinf, 70, 603-608 (2007).
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