Abstracts Posters SICOT-SOF meeting Gothenburg 2010 _2_

Poster
Topic: Arthroplasty - Hip
Abstract number: 25579
USE OF TRANEXAMIC ACID TO REDUCE BLOOD LOSS IN PRIMARY
CEMENTLESS TOTAL HIP ARTHROPLASTY
Vijay KUMAR, Bhavuk GARG, Rajesh MALHOTRA
All India Institute of Medical Sciences, New Delhi (INDIA)
A prospective, randomized, double-blind study was done on 50 patients undergoing
primary cementless total hip arthroplasty to determine the effect of tranexamic acid
on intra- and postoperative blood losses.50 patients were randomized to tranexamic
acid (15 mg/kg) given as a bolus intravenous injection or placebo (normal saline)
given intravenously, 15 minutes before the incision. The intraoperative and
postoperative blood loss and the number of blood transfusions required were
recorded. The patients were screened for Deep Venous Thrombosis using Colour
Doppler imaging on the 10th postoperative day. Hemoglobin level was measured
preoperatively and on 3rd postoperative day. The D-dimer levels were measured
preoperatively and 24 hrs postoperatively.Patients receiving tranexamic acid had a
mean intraoperative blood loss of 410 ml (300-510 ml) vs 615 ml (515-750ml) (p