Abstracts Posters SICOT-SOF meeting Gothenburg 2010 _2_
Abstracts Posters SICOT-SOF meeting Gothenburg 2010 _2_ Abstracts Posters SICOT-SOF meeting Gothenburg 2010 _2_
Poster Topic: Tumours Abstract number: 24435 EN BLOC RESCTION OF OSTEOSARCOMA OF PROXIMAL FIBULA: AN ANALYSIS OF 8 CASES Kamal BALI, Raghav SAINI, Mandeep DHILLON PGIMER, Chandigarh (INDIA) Background and purposeOsteosarcoma of proximal fibula is a rare entity that poses a great surgical challenge to an Orthopaedician. Limb salvage is the goal of treatment and this entails sacrifice of the common peroneal nerve as well as the anterior tibial artery. Also the loss of lateral collateral ligament and biceps attachment leads to unavoidable knee instability which requires special reconstructive procedures.Methods From 2002 to 2008 eight patients with non metastatic osteosarcoma of fibular head were treated in our institution with Malawer type II resection. Special attention was paid to reconstructing lateral collateral ligament and to post operative knee stability. All the patients completed the standard course of neoadjuvant and post operative chemotherapy.ResultsNegative margins were achieved in all the 8 patients and consequently none required secondary resection or amputation. Seven of these patients are still alive without evidence of any disease. . All these patients have full ROM of the knee and no problems in carrying out their activities of daily living. None of the surviving patients has any evidence of local recurrence at the last follow up visit.DiscussionOur results indicate that the sacrifice of common peroneal nerve ensures a wide margin of resection which in turn correlates with long term survival. Also our technique of reconstruction of lateral knee structures has produced good functional outcome without significant postoperative knee instability. 630
Poster Topic: Tumours Abstract number: 24461 PATIENT SURVIVAL AND COMPLICATIONS AFTER SURGERY FOR SKELETAL METASTASES FROM LUNG CANCER Rikard WEDIN, Rüdiger WEISS Department of Orthopaedic Surgery, Karolinska University Hospital, Karolinska Institutet, Stockholm (SWEDEN) Background: The benefit of palliative Orthopaedic surgery for lung cancer patients with bone metastases and a short expected survival is often difficult to predict. The aim of the study was to assess survival rates and to identify predictors of survival after surgery for skeletal metastases. Methods:This study was based on data recorded in the Karolinska Skeletal Metastasis Register. We extracted all lung cancer patients who had surgery due to skeletal metastases 1987 to 2006. Kaplan-Meier and Cox-regression analysis was used calculate cumulative survival and predictors of survival.Results:We identified 98 lung cancer patients treated surgically for skeletal metastases. The median survival time after surgery was 2.6 months. The cumulative 12 months survival after surgery was 13%. There was a statistically significant difference between the median survival after spinal surgery (1.8 months) compared with extremity surgery (3.5 months).Metastatic lesions in the vertebra (OR 1.8, p=0.049), complete pathologic fractures (OR 1.9, p=0.043), low hemoglobin levels (OR 2.8, p=0.004) and the absence of postoperative radiotherapy (OR 1.9, p=0.04) were identified as independent negative predictors of survival.The reoperation rate was 15% and complications treated non-surgically were seen in 5% of the patients.Conclusions:Bone metastases and their subsequent surgical treatment in lung cancer patients are associated with considerable negative effects on both morbidity and mortality. The information in this study helps to set appropriate expectations for these patients, their families and surgeons. 631
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Poster<br />
Topic: Tumours<br />
Abstract number: 24461<br />
PATIENT SURVIVAL AND COMPLICATIONS AFTER SURGERY FOR SKELETAL<br />
METASTASES FROM LUNG CANCER<br />
Rikard WEDIN, Rüdiger WEISS<br />
Department of Orthopaedic Surgery, Karolinska University Hospital, Karolinska<br />
Institutet, Stockholm (SWEDEN)<br />
Background: The benefit of palliative Orthopaedic surgery for lung cancer patients<br />
with bone metastases and a short expected survival is often difficult to predict. The<br />
aim of the study was to assess survival rates and to identify predictors of survival<br />
after surgery for skeletal metastases. Methods:This study was based on data<br />
recorded in the Karolinska Skeletal Metastasis Register. We extracted all lung cancer<br />
patients who had surgery due to skeletal metastases 1987 to 2006. Kaplan-Meier<br />
and Cox-regression analysis was used calculate cumulative survival and predictors<br />
of survival.Results:We identified 98 lung cancer patients treated surgically for skeletal<br />
metastases. The median survival time after surgery was 2.6 months. The cumulative<br />
12 months survival after surgery was 13%. There was a statistically significant<br />
difference between the median survival after spinal surgery (1.8 months) compared<br />
with extremity surgery (3.5 months).Metastatic lesions in the vertebra (OR 1.8,<br />
p=0.049), complete pathologic fractures (OR 1.9, p=0.043), low hemoglobin levels<br />
(OR 2.8, p=0.004) and the absence of postoperative radiotherapy (OR 1.9, p=0.04)<br />
were identified as independent negative predictors of survival.The reoperation rate<br />
was 15% and complications treated non-surgically were seen in 5% of the<br />
patients.Conclusions:Bone metastases and their subsequent surgical treatment in<br />
lung cancer patients are associated with considerable negative effects on both<br />
morbidity and mortality. The information in this study helps to set appropriate<br />
expectations for these patients, their families and surgeons.<br />
631