Abstracts Posters SICOT-SOF meeting Gothenburg 2010 _2_

Poster
Topic: Trauma - Knee
Abstract number: 26259
INTERIMS ANALYSIS OF A MULTICENTER PROSPECTIVE RANDOMIZED
CLINICAL TRIAL COMPARING THE TREATMENT OF FRACTURES OF THE
DISTAL FEMUR AND THE PROXIMAL TIBIA WITH MONO- VS. POLYAXIAL
PLATING SYSTEMS (LISS® VS. NCB® DF/PT)
Peter BIBERTHALER 1 , Marc HANSCHEN 1 , Ina ASCHENBRENNER 1 , Sonja
KIRCHHOFF 2 , Leonhard KEIL 1 , Florian GEBHARD 3 , Sven LüHRS 3 , Rainer
MEFFERT 4 , Andreas BERGLEHNER 4 , Kai FEHSKE 4 , Rainer NEUGEBAUER 5 ,
Bernd FüCHTMEIER 5 , Sebastian WINKLER 5 , Wolf MUTSCHLER 1
1 Department of Trauma and Orthopaedic Surgery, Ludwig-Maximilians-University,
Munich (GERMANY), 2 Department of Diagnostic Radiology, LMU, Munich
(GERMANY), 3 Department of Trauma and Orthopaedic Surgery, University of Ulm,
Ulm (GERMANY), 4 Department of Trauma and Orthopaedic Surgery, University of
Wuerzburg, Wuerzburg (GERMANY), 5 Department of Trauma and Orthopaedic
Surgery, Krankenhaus Barmherzige Brüder Regensburg, Regensburg (GERMANY)
Treatment of complex fractures of the knee (distal femur / proximal tibia) utilizing
monoaxial locking plates (e.g. Less Invasive Stabilisation System, LISS®, Synthes) is
considered superior to conventional plating systems. Due to the limitation that the
thread forces the screw into pre-determined positions, modifications have been made
to allow screw positioning within a range of 30° (N on Contact Bridging, NCB®,
Zimmer). For the first time, this multicenter prospective randomized clinical trial
(RCT) investigates the outcome of LISS®- vs. NCB®-treatment following complex
knee fractures. Since June 2008 patients with a fracture of the distal femur or the
proximal tibia (AO ASIF 41-A2, 41-A3, 41-C or 33-A2, 33-A3, 33-C) are enrolled to
this study by four trauma centers in southern Germany. The study aims to include 90
patients. Follow-ups are done 1 and 6 weeks, as well as 3, 6, and 12 months
following the operation. Radiologic data (e.g. axis deviation, secondary loss of
realignment) as well as clinical data (e.g. pain, wound healing, Oxford Knee Score,
Tegner Score) are collected. The interims analysis can revert to data of 50 patients at
this time (27m, 23f; 27 NCB®, 23 LISS®). Up to now, no significant differences in the
radiologic and clinical data can be observed. We present the interims analysis of a
multicenter prospective RCT to compare the monoaxial LISS® vs. the polyaxial
NCB® treatment following complex knee fractures. The dependance on utilization
observations and lack of comparison between these systems emphasize this studies
relevance.
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