Abstracts Posters SICOT-SOF meeting Gothenburg 2010 _2_
Abstracts Posters SICOT-SOF meeting Gothenburg 2010 _2_ Abstracts Posters SICOT-SOF meeting Gothenburg 2010 _2_
Poster Topic: Arthroplasty - Hip Abstract number: 24290 PHYSICAL FUNCTIONING AND HEALTH-RELATED QUALITY OF LIFE AFTER TOTAL HIP REPLACEMENT Plamen KINOV, Encho YANKOV University Hospital Queen Giovanna - ISUL, Sofia (BULGARIA) Total hip replacement (THR) is an effective surgical intervention for treatment of endstage arthritis. Clinical outcome can be assessed in many different ways by both patient and surgeon. Health-related quality of life is acknowledged to be the primary aim of surgical treatment and various authors have recommended that selfadministered tools should be included when evaluating results. Aim: Evaluation of effect of THR on physical functioning and health-related quality of life.Material and methods: 63 patients hospitalized for elective hip replacement were evaluated with Short Form 8 Health Survey (SF-8) and Western Ontario and McMaster University Osteoarthritis Index (WOMAC). Harris hip score was used for surgeon’s assessment of clinical result. The mean follow up period was 3 years. Results: The eight domains of SF-8 as well as the other two instruments showed significant improvement at three months after surgery that lasted till the final follow-up. We established good correlation between the instruments. Patients with poor preoperative function measured with WOMAC had greater improvement, however, less optimal outcome. Discussion and conclusions: Our findings confirm the effectiveness of THR outcomes in terms of physical functioning and health-related quality of life measured by selfadministered disease-specific (WOMAC) and generic health instruments (SF-8). Expectations of patients on outcome after treatment are ever higher and this raises the standard of outcome after surgical treatment. Use of subjective and objective instruments improves assessment of the benefit of THR. 44
Poster Topic: Arthroplasty - Hip Abstract number: 24322 CAN RISEDRONATE GIVEN ONCE A WEEK FOR SIX MONTHS PREVENT PERIPROSTHETIC BONE RESORPTION UP TO TWO YEARS AFTER TOTAL HIP ARTHROPLASTY? A RANDOMIZED, DOUBLE-BLIND, PLACEBO- CONTROLLED, PROSPECTIVE TRIAL Olof SKÖLDENBERG, Mats SALEMYR, Henrik BODéN, Torbjörn AHL, Per ADOLPHSON Karolinska Institutet, Department of Clinical Sciences at Danderyd Hospital, Stockholm (SWEDEN) Background: Postoperative bone loss due to stress-shielding around uncemented femoral stems used in total hip arthroplasty is a well-known phenomenon. Randomized clinical trials have shown that it is possible to reduce the bone loss using bisphosphonates, but there are conflicting evidence regarding the effect of risedronate for this indication. We performed a randomized clinical trial with risedronate given once weekly in patients receiving a primary total hip arthroplasty. Methods: 70 patients (43 females) age mean (range) 61 (41-69) years with osteoarthritis were randomized to either placebo or risedronate 35 mg once weekly for 6 months after a total hip arthroplasty. Dual-energy x-ray absorptiometry was used to measure change in bone mineral density and Ein-Bild-Roentgen-Analyse to measure migration. Primary outcome variable was change in bone mineral density and migration of the uncemented femoral stem up to 2 years postoperatively. The analysis was done according to the intention-to-treat principle. Results: The results will be presented. Discussion: Bisphosphonates have earlier been shown to reduce bone resorption around uncemented femoral stems and to reduce migration of knee prosthesis. The effect of risedronate on bone metabolism and periprosthetic bone resorption after total hip arthroplasty have earlier only been studied with a low number of patients, short follow-up (1) and not according to intention-to treat.1. Yamasaki S, Masuhara K, Yamaguchi K, Nakai T, Fuji T, Seino Y. Risedronate reduces postoperative bone resorption after cementless total hip arthroplasty. Osteoporos Int 2007;18-7:1009-15. 45
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Poster<br />
Topic: Arthroplasty - Hip<br />
Abstract number: 24290<br />
PHYSICAL FUNCTIONING AND HEALTH-RELATED QUALITY OF LIFE AFTER<br />
TOTAL HIP REPLACEMENT<br />
Plamen KINOV, Encho YANKOV<br />
University Hospital Queen Giovanna - ISUL, Sofia (BULGARIA)<br />
Total hip replacement (THR) is an effective surgical intervention for treatment of endstage<br />
arthritis. Clinical outcome can be assessed in many different ways by both<br />
patient and surgeon. Health-related quality of life is acknowledged to be the primary<br />
aim of surgical treatment and various authors have recommended that selfadministered<br />
tools should be included when evaluating results. Aim: Evaluation of<br />
effect of THR on physical functioning and health-related quality of life.Material and<br />
methods: 63 patients hospitalized for elective hip replacement were evaluated with<br />
Short Form 8 Health Survey (SF-8) and Western Ontario and McMaster University<br />
Osteoarthritis Index (WOMAC). Harris hip score was used for surgeon’s assessment<br />
of clinical result. The mean follow up period was 3 years. Results: The eight domains<br />
of SF-8 as well as the other two instruments showed significant improvement at three<br />
months after surgery that lasted till the final follow-up. We established good<br />
correlation between the instruments. Patients with poor preoperative function<br />
measured with WOMAC had greater improvement, however, less optimal outcome.<br />
Discussion and conclusions: Our findings confirm the effectiveness of THR outcomes<br />
in terms of physical functioning and health-related quality of life measured by selfadministered<br />
disease-specific (WOMAC) and generic health instruments (SF-8).<br />
Expectations of patients on outcome after treatment are ever higher and this raises<br />
the standard of outcome after surgical treatment. Use of subjective and objective<br />
instruments improves assessment of the benefit of THR.<br />
44