Abstracts Posters SICOT-SOF meeting Gothenburg 2010 _2_

Poster
Topic: Osteoporosis
Abstract number: 25221
THE PRECISION OF DIGITAL X-RAY RADIOGRAMMETRY COMPARED WITH
DXA IN WOMEN AT RISK OF OSTEOPOROTIC FRACTURE: RESULTS FROM A
PROSPECTIVE AND MULTICENTRIC STUDY.
Manuel Angel SANDOVAL 1 , Alfonso NORIEGA 1 , Jose MF CARREIRA 1 , Daniel
HERNANDEZ-VAQUERO 2
1 Hospital San Agustin, Aviles (SPAIN), 2 Facultad de Medicina, Universidad de
Oviedo, Oviedo (SPAIN)
OBJECTIVE: Identification of patients with high risk of osteoporotic fracture by means
of digital X-ray radiogrammetry (DXR) like simple and accessible method.
METHODS: Were studied prospectively 350 white women (55-65 years). The
multicentric Osteoporosis Group was composed by 8 public hospitals from the North
of Spain. There was practised a standard X-ray of the non-dominant hand, which
later it was scanned. By means of Sectra Osteoporosis Package specific software
(Linköping, Sweden), we selected three regions of interest on the three central
metacarpals. We realised also a Dual energy X-ray absorptiometry (DXA) in a control
group of 20 persons. We studied the association of the osteoporosis with the
analyzed risk factors by means of risk-reasons when the precedence to the
osteoporosis is biologically reasonable and by means of prevalence-reasons for the
factors whose temporary sequence of causality cannot be determined. Cronbach alfa
reliability test, reliability and reproducibility estimated by the Spearman's correlation,
and concurring validation through Spearman's correlation were used. RESULTS: We
found that DXR has excellent precision of 0.004 g/cm2 compared with 0.021 g/cm2
and 0.015 g/cm2 obtained by DXA at the hip and spine, respectively. This study was
considered consistent (Cronbach alfa = 0.83) and valid (p =0.03). CONCLUSIONS:
We conclude that DXR measured by the automated Sectra system has excellent
precision and seems to provide meaningful information on bone mass in
epidemiological studies, where DXA measurements are not available.
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