Abstracts Posters SICOT-SOF meeting Gothenburg 2010 _2_

Poster
Topic: Minimally Invasive Surgery - Hip
Abstract number: 24122
TRANEXAMIC ACIDS REDUCE BLOOD LOSS IN MINIMALLY INVASIVE THA
Tsuyoshi NAKAI 1 , Keiichi FUJIMOTO 2 , Masaaki KAKIUCHI 2
1 Itami City Hospital, Itami (JAPAN), 2 Osaka Police Hospital, Osaka (JAPAN)
Tranexamic acid has been reported to reduce intraoperative and postoperative blood
loss in patients undergoing total hip arthroplasty. To our knowledge, however, there
have been no reports describing the effects of tranexamic acid on blood loss during
and following minimally invasive total hip arthroplasty (MIS-THA). We investigated
the effects of tranexamic acid in 81 patients who underwent MIS-THA without cement
for the treatment of osteoarthritis of the hip. There were 20 men and 61 women. The
mean age at the time of surgery was 66 years, and the mean BMI was 24.1. ±1000
mg of tranexamic acid was administered intravenously five minutes before the skin
incision and just before the skin closure, dependently. Baseline hemoglobin and
hematocrit values were obtained three weeks before operation. Postoperative
hemoglobin and hematocrit values were obtained at one day, one week, and two
weeks. Operative time averaged 80 minutes, and average intraoperative blood loss
was 340 ml. We use no suction drain in all cases. The greatest reduction in the level
of hemoglobin and hematocrit values during the postoperative period was observed
in one week after operation. We needed neither autologous nor allogeneic blood
transfusion postoperatively. There was no evidence of deep vein thrombosis or event
of any infections, and haematoma. The use of tranexamic acids in MIS-THA could be
an effective and safe means to reduce blood loss and the need for blood transfusion
requirements.
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