Abstracts Posters SICOT-SOF meeting Gothenburg 2010 _2_

Poster
Topic: Infections
Abstract number: 23766
IMPLANTS COATING WITH REGULATED ANTIBACTERIAL PROPERTIES
Volodymyr RADCHENKO 1 , Mykola KORZH 1 , Ninel DEDUKH 1 , Vytaliy BELOUS 2
1 Sytenko Institute of Spine and Joint Pathology, Kharkiv (UKRAINE), 2 Institute of
Phisics Technology, kharkiv (UKRAINE)
Infection complications in the postoperative period are very often the reason to
unsatisfactory results of applying metallic implants in surgery of the locomotorium
involving the problem of removing endoprostheses, metallic construction. Purpose:
Jo develop coatings onto the metallic fixators with regulated bactericidal
(antibacterial) properties. Materials and methods: Metallic constructions with the
coatings prepared on the basis of titanium dioxide and processed by the ions
streams served as a material. The coatings were obtained by way of falling out the
streams of titanium plasma generated by the arch of low pressure in the rarefied
oxygen atmosphere. Activation of antibacterial properties took place under influence
of X-ray impact. Antibacterial properties were evaluated in the Petri dish together with
St.Aurus (209) in the amount of 1×109 microorganisms per cup. Cultivation was done
during 1,2, u 3 days. The specimens laving bactericidal coatings were implanted into
the hip bone of the rats for assessment of the results. Results: When evaluating the
results in the Petri dish antibacterial activity around the implants with coatings after
processing them with the X-rays was noticed. And after intrabone implantation of the
specimens it was shown that the material of the coating did not influence reparative
osteogenesis. The index of osteointegration of the coating material with new formed
bone tissue is 82,4 ± 12,2.Conductions. New coatings which properties can be
activated by way of X-ray impact were developed for the titanium fixators.
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