Abstracts Posters SICOT-SOF meeting Gothenburg 2010 _2_

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$Percutaneous Fixation for Pipkin type II Femoral head fracture ... - sicot$

$Tibial plateau fracture primarily treated with knee arthroplasty - sicot$

Poster Topic: Cartilage Repair Abstract number: 26163 FUNCTIONAL OUTCOME FOLLOWING COMBINED SIMULTANEOUS AUTOLOGOUS CHONDROCYTE IMPLANTATION AND HIGH TIBIAL OSTEOTOMY Syed NAWAZ, Michael TR PARRATT, Simon MACMULL, Panos GIKAS, Richard CARRINGTON, Timothy WR BRIGGS, John SKINNER, George BENTLEY Royal National Orthopaedic Hospital, Stanmore, London (UNITED KINGDOM) High tibial osteotomy (HTO) and Autologous chondrocyte implantation is a recognised method of correction for knee joint malalignment, unicompartmental osteoarthritis and osteochondral defects. This study evaluates the functional outcome in a group of twenty three patients undergoing a combined ACI-HTO procedure identified retrospectively from a larger cohort undergoing ACI procedure. The mean follow-up was 54 months (range 12 - 108) and the mean defect size was 689 mm2 (range 350 - 1200). Nine patients had ACI-C and HTO, the remainder having MACI and HTO. The Mean VAS score improved from 7.4 pre-operatively to 2.9 post-operatively (p
Poster Topic: Cartilage Repair Abstract number: 26763 DEVELOPMENT OF A STRUCTURALLY GRADED POLYCAPROLACTONE (SG- PCL) SCAFFOLDS FOR HYALINE CARTILAGE REPAIR Bjørn B CHRISTENSEN 1 , Casper B FOLDAGER 1 , Dang LE 2 , Cody BÜNGER 1 , Jens VINGE 1 , Martin LIND 1 1 2 Aarhus University Hospital, Aarhus (DENMARK), Aarhus University, Ny Munkegade, Aarhus (DENMARK), INTRODUCTION: Articular cartilage defects have shown a limited potential to heal, which can lead to pain, swelling, and early osteoarthritis. The aim of this study is to develop a novel SG-PCL scaffold for hyaline cartilage repair. METHODS: A novel SG-PCL scaffold was constructed using rapid prototyping. PCL fibers (MW 50 kDa) with a diameter of 120 µm were plotted producing a 3D web. The scaffold was subsequently submerged into a mixture of dioxane, PCL and water, and lyophilized at -32°C, creating an extremely porous graded struc ture. By shifting the water/dioxane ratio 16 scaffolds with different pore sizes were made. Using scanning electron microscopy, two scaffolds were selected. The two scaffolds were then constructed with either 25kDa or 50kDa graded structure giving a total of four different scaffold. They were cultured with human chondrocytes and the viability was analyzed using confocal microscopy after 1, 3 and 6 days. The scaffolds were rated based on cell migration, cell shape and distribution of viable cells. RESULTS: The scaffolds contained macro-, micro-, and nano-pores. A large difference in investigated parameters was observed and a water-dioxane ratio of 0.0415 provided the most viable environment for chondrocytes according to the above-mentioned criteria. CONCLUSION: We successfully constructed a SG-PCL scaffold that can be used in future in vivo experiments, and has the potential of subsequent functionalization with nano particles and growth- and differentiation factors 199
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Seventh SICOT/SIROT Annual Internat
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Poster Topic: Arthroplasty - Elbow
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Poster Topic: Arthroplasty - Hand/W
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Poster Topic: Arthroplasty - Hip Ab
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Poster Topic: Arthroplasty - Knee A
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Poster Topic: General Orthopaedics
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Poster Topic: Infections Abstract n
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Poster Topic: Minimally Invasive Su
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Poster Topic: Navigation Abstract n
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Poster Topic: Osteoporosis Abstract
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Poster Topic: Paediatrics Abstract
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Poster Topic: Spine Abstract number
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Poster Topic: Sports Medicine - Ank
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Poster Topic: Sports Medicine - Elb
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Poster Topic: Sports Medicine - Han
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Poster Topic: Sports Medicine - Hip
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Poster Topic: Sports Medicine - Hip
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Poster Topic: Sports Medicine - Sho
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Poster Topic: Sports Medicine - Spi
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Poster Topic: Sports Medicine - Sys
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Poster Topic: Trauma - Ankle / Foot
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Poster Topic: Trauma - Elbow Abstra
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Poster Topic: Trauma - Femur Abstra
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Poster Topic: Trauma - Forearm Abst
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Poster Topic: Trauma - Hand/Wrist A
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Poster Topic: Trauma - Hip Abstract
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Poster Topic: Trauma - Knee Abstrac
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Poster Topic: Trauma - Shoulder Abs
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Poster Topic: Trauma - Spine Abstra
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Poster Topic: Trauma - Systemic Abs
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Poster Topic: Trauma - Tibia/Fibula
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Poster Topic: Tumours Abstract numb
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Abstracts Posters SICOT-SOF meeting Gothenburg 2010 _2_

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