Abstracts Posters SICOT-SOF meeting Gothenburg 2010 _2_

Poster
Topic: Cartilage Repair
Abstract number: 25403
RESULTS OF KNEE CARTILAGE INJURY TREATMENT BY ARTHROSCOPIC
OSTEOCHONDRAL AUTOGRAFT USING PSEUDOSYNOVIAL LIQUID
Oleg EISMONT, Bahdan MALIUK, Dmitrij BUKACH, Vajcheslaw BUKACH
Republican Scientific Practical Centre of Traumatology and Orthopaedic Surgery,
Minsk, Belarus, Minsk (BELARUS)
Study of chondro- and osteointegration of autografts in animal models and evaluation
of remote results of osteochondral autograft in knee joint cartilage injury. We
analyzed the results of osteochondral autograft surgeries in patients by OATS
(osteochondral autograft transplantation system). Surgery was indicated in cases
with full-thickness isolated cartilage defects in the stressed zones of femoral
condyles of the knee joint with subchondral plate stripping and total area not
exceeding 4 cm2. In 66,7% cases, cartilage damaged occurred as the result of acute
or chronic joint trauma, in 33,3% cases it was caused by osteochondritis dissecans.
Treatment results were evaluated 4-7 years after the surgery on Lysholm-Tegner
Scale. Chondro- and osteointegration was studied in experimental dog models of fullthickness
damage of knee joint cartilage. Pseudosynovial liquid containing the
mixture of cholesteric-nematic liquid crystals in 2% Na-CMC water solution. In this
animal study, chondro- and osteointegration of autograft with the surrounding hyaline
cartilage and host bone bed was reported 2,5 months after osteochondral autograft
transplantation. Pseudosynovial liquid stimulated the process and facilitated
activation of chondrogenesis, improvement of reproductive functions of cartilage
cells, formation of interfacial regenerated cartilage tissue from hyaline cartilage, and
practical absence of dystrophic changes in cartilage matrix. Analysis of the remote
results of treatment of knee cartilage defects by osteochondral autograft
transplantation revealed excellent and good results in most cases (92,6%).
Satisfactory cases were connected with the development of joint cartilage
chondromalacia around the autograft and on the opposite joint surface of the tibial
plateau.
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