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Abstracts Posters SICOT-SOF meeting Gothenburg 2010 _2_

Abstracts Posters SICOT-SOF meeting Gothenburg 2010 _2_

Abstracts Posters SICOT-SOF meeting Gothenburg 2010 _2_

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Poster<br />

Topic: Arthroplasty - Systemic<br />

Abstract number: 26295<br />

THE GRADE OF RADIOLOGICAL CHANGES AND HISTOLOGICAL<br />

INFLAMMATION DOES NOT PREDICT OUTCOME AFTER TOTAL KNEE<br />

REPLACEMENT FOR OSTEOARTHRITIS<br />

Henrik LUNDBLAD, Andris KREICBERGS, Veli SÖDERLUND, Ann-Kristin<br />

ULFGREN, Carl-Olav STILLER, Karl-Åke JANSSON<br />

Karolinska Institute, Stockholm (SWEDEN)<br />

We investigated the relationship between radiological and inflammatory changes on<br />

one hand and osteoarthritic pain and pain thresholds on the other. In 69 patients<br />

scheduled for total knee arthroplasty (TKA) preoperative radiographs and histological<br />

samples of the synovial membrane were graded for severity of osteoarthritic and<br />

inflammatory changes. Preoperative pain at rest and with movement as well as the<br />

pain threshold to electrical stimulus was assessed preoperatively and 18 months<br />

postoperatively. Our analysis indicates that the grade of radiological or histological<br />

changes in osteoarthritis is poorly related to pain and outcome and therefore of<br />

limited value for the selection of patients for TKA. Presumably pain before and after<br />

TKA in osteoarthritis is determined by mechanisms unrelated to local morphological<br />

changes.<br />

163

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