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Abstracts Posters SICOT-SOF meeting Gothenburg 2010 _2_

Abstracts Posters SICOT-SOF meeting Gothenburg 2010 _2_

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Poster<br />

Topic: Arthroplasty - Systemic<br />

Abstract number: 25444<br />

ORAL VERSUS INJECTABLE ANTI-COAGULATION: A SURVEY OF PATIENT<br />

PERCEPTION FOLLOWING TOTAL HIP AND KNEE ARTHROPLASTY<br />

Louy GHAZAL, Olufemi OYEKANMI, Umiya AGGRAVAL, Tharaka<br />

CHANDRAKUMAR, Aaron NG<br />

Manchester Royal Infirmary, Manchester (UNITED KINGDOM)<br />

Background: The UK National Institute for Clinical Excellence (NICE) has<br />

recommended the use of the new oral anticoagulant Xarelto® (rivaroxaban) over<br />

injectable low molecular weight heparin (LMWH) in adults undergoing elective hip or<br />

knee arthroplasty surgery. Aim: To assess patients’ perception of use of oral<br />

anticoagulation versus injectable LMWH therapy after hip and knee arthroplasty.<br />

Materials And Methods: A survey was conducted between August 2009 and<br />

November 2009 of 50 patients (age range, 35 - 84 years, mean 65 years) receiving<br />

injectable LMWH for VTE prophylaxis after total hip and knee replacement surgery.<br />

The survey focused on preference, compliance, efficacy and safetyResults: A<br />

significantly larger proportion preferred tablet prophylaxis to injections postoperatively<br />

(68% Vs 26%). Older patients preferred tablets while younger patients preferred<br />

injections (mean age 66.7 yrs vs. 61.7 yrs). Of the patients who preferred injection<br />

prophylaxis, perceived compliance with tablet prophylaxis was less likely than<br />

injections (38.46% Vs 53.85 %,). In those favouring tablet prophylaxis, a significantly<br />

greater number of patients felt they would be compliant (82% vs. 18%), despite these<br />

same patients perceiving injections as more clinically efficacious than tablets<br />

(67.65% vs. 14.70%). Perception on safety between both methods was similar.<br />

Conclusion: Our sample preferred oral anticoagulation following arthroplasty surgery.<br />

However patients should be given an informed choice of anticoagulation as<br />

differences in age and preference may affect compliance<br />

161

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