Abstracts Posters SICOT-SOF meeting Gothenburg 2010 _2_

Poster
Topic: Arthroplasty - Knee
Abstract number: 25142
MORPHO-FUNCTIONAL CHARACTERISTICS OF OSTEOARTHROSIS AND
THEIR CHANGES AFTER ARTHROPLASTY OF KNEE JOINT
Ludmila PASHKEVICH, Olga SHALATONINA, Taher MOHAMMADI
Belarusian Research Center of Traumatology and Orthopaedic Surgery, Minsk
(BELARUS)
The aim of investigation is to determine the condition of osteo-cartilage structures
and function of neurumuscular apparatus of low extremities. 110 patients with III-IV
stage have been examined using the method of surface and stimulating
electromyography diagnosed radiologically and verified morphologically after
endoprosthesis. For histological examination the slides were painted with H&E, and
DNA, RNA, glucogen, acid and alkaline phosphatase, S-100 and Ki-67. The
decrease of bioelectric activity has been revealed m.vastus lateralis and m.vastus
medialis to 55-72% in injured and to 22% in intact extremity. According to EMG the
decrease of amplitude H-reflex and M-answers m.soleus has been revealed to 40
and 30% accordingly. On the 14th day after arthoroplasty of the injured joint
electromyographic activity has been decreased to 80-85% and its incomplete
restoration was observed in 3-6 months. In the operative material studies of the knee
joint removed during total endoprosthetis osteoarthrosis III-IV degree was observed
histologically. Thus apparent destructive-dystrophic changes were market.
Morphometric investigation revealed osteoporosis in the areas less loaded and
osteosclerosis in more loaded areas. Thus the mean value of the occupied area of
bone trabuculae was 14.98 ± 0.78 % and 56.80 ± 1.50 % accordingly. Proliferative,
dystrophic, necrobiotic, sclerotic and inflammatory processes of difert degree
evidence and distribution were observed in synovial membranes. The results of the
investigation carried out hate been applied in diagnosing the disease and
scientifically grounded necessity for joint replacement.
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