Acknowledgment to Reviewers - Circulation Research - American ...
Acknowledgment to Reviewers - Circulation Research - American ... Acknowledgment to Reviewers - Circulation Research - American ...
Acknowledgment to Reviewers The editors express appreciation to the following consultants who served from January 1992 through June 1992. Adelman, William J. Jr. Adelstein, Robert S. Alexander, R. Wayne Allen, David Allen, Julius Allen, Paul M. Alpert, Norman R. Altschuld, Ruth Anderson, Page Anderson, Sharon Anderson, Warwick P. Andresen, Michael C. Angus, James A. Antzelevitch, Charles Anversa, Piero Apstein, Carl S. Aronson, Ronald S. Arts, Theodore Ashraf, Muhammed Ashton, Julie H. Attinger, Ernst 0. Aversano, Thomas Aviv, Abraham Bacaner, Marvin Bache, Robert J. Backx, Peter Bader, David Baker, Kenneth M. Balaban, Robert S. Balligand, Jean-Luc Barber, Michael Barman, Susan Barr, Roger Barry, William Baserga, Renato Bassenge, Eberhard L. Bassingthwaight, James Baumgarten, Clive Bean, Bruce Beasley, Debbie Becker, Lewis C. Belloni, Frank Benedict, Claude Bennett, Paul B. Benson, D. Woodrow Bentley, Michael Berberian, Paul A. Berdeaux, Alain Berk, Bradford C. Berlin, Joshua R. Berne, Robert M. Bernstein, Kenneth E. Bers, Donald Bevan, John A. Beyer, Eric C. Bigaud, Marc Bigger, J. Thomas Jr. Bing, Oscar Birdsall, Nigel Bishop, Sandford Bishop, Vernon S. Bittl, John Blank, Randal S. Blinks, John R. Block, Kenneth Bloor, Colin M. Bohlen, Glenn H. Bolli, Roberto Bond, Meredith Bond, Robert F. Booyse, Francoise Botney, Mitchel Boulanger, Chantal M. Boyden, Penelope Brain, Susan Brecher, Peter L. Bredt, David Bridge, John Briggs, F. Norman Bristow, Michael R. Britton, Steven Loyal Brock, Thomas A. Brown, Arthur M. Brutsaert, Dirk L. Bucala, Richard Buja, L. Maximilian Bunag, Rubin D. Burnett, John Burnstock, Geoffrey Burt, Janis Busija, David Busse, Rudi Buxton, Denis Campbell, Donald Campbell, Kenneth P. Campbell, William B. Canessa, Mitzy L. Canty, John M. Jr. Capaldi, Roderick A. Capasso, Joseph Capogrossi, Maurizio Carabello, Blase Carew, Tom Carey, David Carmeliet, Edward Carroll, John Case, Robert B. Caskey, C. Thomas Casscells, Ward Castellot, John Catterall, William A. Chachques, Juan C. Chapleau, Mark Charles, Cecil Chen, Peng Chesebro, James H. Chiarello, Massimo Chien, Kenneth Chien, Shu Chilian, William M. Chinard, Francis Chisholm, Guy Clapham, David Clark, Burton Clarkson, Craig Claycomb, William C. Clinton, Steven K. Clowes, Alexander W. Clusin, William Cobb, Frederick R. Cohen, Michael V. Cohen, Richard Cohen, Richard A. Colatsky, Thomas J. Coller, Barry Collins, Tucker Colucci, Wilson S. Constantine, Jay W. Cook, James A. Cooke, John Cooper, George IV Coronado, Roberto Corr, Peter B. Cox, Robert H. Creager, Mark Cronstein, Bruce Crozetier, Bertrand Cua, William Cukierman, Samuel Cupples, William A. Currie, Mark Curry, Fitz Roy Danilo, Peter Davies, Peter F. Davis, Michael J. DeFelice, Louis De Haan, Robert DeMey, Jo G.R. DeTombe, Pieter de Wardener, Hugh Deckelbaum, Lawrence I. Dellsperger, Kevin Dhalla, Naranjan S. DiBona, Gerald F. Dichek, David DiCorleto, Paul Diglio, Clement A. Dillman, Wolfgang H. Dillon, Stephen Dobson, James Douglas, Pamela Downey, James M. Dubyak, George R. Duling, Brian Dunn, Michael J. Dusting, Greg J. Echt, Deborah Edelman, Elezar Edvinsson, Lars Eghbali, Mahboubeh Eisner, David Endoh, Masao Eng, Calvin Engler, Robert Entman, Mark Escande, Denis Eskin, Suzanne Esler, Murray Etingin, Orli R. Ezekowitz, Michael Fabiato, Alexandre Fagin, James Fallon, John Fanburg, Barry L. Fanestil, Darrell D. Fanestil, David Faraci, Frank Farber, Harrison Faxon, David Fedida, David Feher, Joseph J. Feigl, Eric Feinstein, Steven Felder, Robert B. Feldman, Arthur Feneley, Michael P. Ferguson, Donald G. Ferrans, Victor J. Feuerstein, Giora Fingerle, Jurgen Fink, Gregory Fishman, Donald Fishman, Glenn I. Fishman, Mark C. Fitzgerald, Garrett A. Flabahan, Nicholas Flaherty, John T. Fleischer, Sidney Fletcher, J. Raymond Folkow, Bjorn U.G. Folts, John D. Foster, Robert E. II Fox, Paul Fozzard, Harry Francis, Gary S. Franzblau, Carl Freeman, Gregory Frizzell, Raymond A. Fuster, Valentin Gaasch, William Gallagher, Kim Galper, Jonas B. Ganten, Detlev Ganz, Peter George, Sam Gerritsen, Mary Gettes, Leonard Gewirtz, Henry Ghai, Geetha Giles, Wayne 1539
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<strong>Acknowledgment</strong> <strong>to</strong> <strong>Reviewers</strong><br />
The edi<strong>to</strong>rs express appreciation <strong>to</strong> the following consultants who served from January 1992 through June 1992.<br />
Adelman, William J. Jr.<br />
Adelstein, Robert S.<br />
Alexander, R. Wayne<br />
Allen, David<br />
Allen, Julius<br />
Allen, Paul M.<br />
Alpert, Norman R.<br />
Altschuld, Ruth<br />
Anderson, Page<br />
Anderson, Sharon<br />
Anderson, Warwick P.<br />
Andresen, Michael C.<br />
Angus, James A.<br />
Antzelevitch, Charles<br />
Anversa, Piero<br />
Apstein, Carl S.<br />
Aronson, Ronald S.<br />
Arts, Theodore<br />
Ashraf, Muhammed<br />
Ash<strong>to</strong>n, Julie H.<br />
Attinger, Ernst 0.<br />
Aversano, Thomas<br />
Aviv, Abraham<br />
Bacaner, Marvin<br />
Bache, Robert J.<br />
Backx, Peter<br />
Bader, David<br />
Baker, Kenneth M.<br />
Balaban, Robert S.<br />
Balligand, Jean-Luc<br />
Barber, Michael<br />
Barman, Susan<br />
Barr, Roger<br />
Barry, William<br />
Baserga, Rena<strong>to</strong><br />
Bassenge, Eberhard L.<br />
Bassingthwaight, James<br />
Baumgarten, Clive<br />
Bean, Bruce<br />
Beasley, Debbie<br />
Becker, Lewis C.<br />
Belloni, Frank<br />
Benedict, Claude<br />
Bennett, Paul B.<br />
Benson, D. Woodrow<br />
Bentley, Michael<br />
Berberian, Paul A.<br />
Berdeaux, Alain<br />
Berk, Bradford C.<br />
Berlin, Joshua R.<br />
Berne, Robert M.<br />
Bernstein, Kenneth E.<br />
Bers, Donald<br />
Bevan, John A.<br />
Beyer, Eric C.<br />
Bigaud, Marc<br />
Bigger, J. Thomas Jr.<br />
Bing, Oscar<br />
Birdsall, Nigel<br />
Bishop, Sandford<br />
Bishop, Vernon S.<br />
Bittl, John<br />
Blank, Randal S.<br />
Blinks, John R.<br />
Block, Kenneth<br />
Bloor, Colin M.<br />
Bohlen, Glenn H.<br />
Bolli, Rober<strong>to</strong><br />
Bond, Meredith<br />
Bond, Robert F.<br />
Booyse, Francoise<br />
Botney, Mitchel<br />
Boulanger, Chantal M.<br />
Boyden, Penelope<br />
Brain, Susan<br />
Brecher, Peter L.<br />
Bredt, David<br />
Bridge, John<br />
Briggs, F. Norman<br />
Bris<strong>to</strong>w, Michael R.<br />
Brit<strong>to</strong>n, Steven Loyal<br />
Brock, Thomas A.<br />
Brown, Arthur M.<br />
Brutsaert, Dirk L.<br />
Bucala, Richard<br />
Buja, L. Maximilian<br />
Bunag, Rubin D.<br />
Burnett, John<br />
Burns<strong>to</strong>ck, Geoffrey<br />
Burt, Janis<br />
Busija, David<br />
Busse, Rudi<br />
Bux<strong>to</strong>n, Denis<br />
Campbell, Donald<br />
Campbell, Kenneth P.<br />
Campbell, William B.<br />
Canessa, Mitzy L.<br />
Canty, John M. Jr.<br />
Capaldi, Roderick A.<br />
Capasso, Joseph<br />
Capogrossi, Maurizio<br />
Carabello, Blase<br />
Carew, Tom<br />
Carey, David<br />
Carmeliet, Edward<br />
Carroll, John<br />
Case, Robert B.<br />
Caskey, C. Thomas<br />
Casscells, Ward<br />
Castellot, John<br />
Catterall, William A.<br />
Chachques, Juan C.<br />
Chapleau, Mark<br />
Charles, Cecil<br />
Chen, Peng<br />
Chesebro, James H.<br />
Chiarello, Massimo<br />
Chien, Kenneth<br />
Chien, Shu<br />
Chilian, William M.<br />
Chinard, Francis<br />
Chisholm, Guy<br />
Clapham, David<br />
Clark, Bur<strong>to</strong>n<br />
Clarkson, Craig<br />
Claycomb, William C.<br />
Clin<strong>to</strong>n, Steven K.<br />
Clowes, Alexander W.<br />
Clusin, William<br />
Cobb, Frederick R.<br />
Cohen, Michael V.<br />
Cohen, Richard<br />
Cohen, Richard A.<br />
Colatsky, Thomas J.<br />
Coller, Barry<br />
Collins, Tucker<br />
Colucci, Wilson S.<br />
Constantine, Jay W.<br />
Cook, James A.<br />
Cooke, John<br />
Cooper, George IV<br />
Coronado, Rober<strong>to</strong><br />
Corr, Peter B.<br />
Cox, Robert H.<br />
Creager, Mark<br />
Cronstein, Bruce<br />
Crozetier, Bertrand<br />
Cua, William<br />
Cukierman, Samuel<br />
Cupples, William A.<br />
Currie, Mark<br />
Curry, Fitz Roy<br />
Danilo, Peter<br />
Davies, Peter F.<br />
Davis, Michael J.<br />
DeFelice, Louis<br />
De Haan, Robert<br />
DeMey, Jo G.R.<br />
DeTombe, Pieter<br />
de Wardener, Hugh<br />
Deckelbaum, Lawrence I.<br />
Dellsperger, Kevin<br />
Dhalla, Naranjan S.<br />
DiBona, Gerald F.<br />
Dichek, David<br />
DiCorle<strong>to</strong>, Paul<br />
Diglio, Clement A.<br />
Dillman, Wolfgang H.<br />
Dillon, Stephen<br />
Dobson, James<br />
Douglas, Pamela<br />
Downey, James M.<br />
Dubyak, George R.<br />
Duling, Brian<br />
Dunn, Michael J.<br />
Dusting, Greg J.<br />
Echt, Deborah<br />
Edelman, Elezar<br />
Edvinsson, Lars<br />
Eghbali, Mahboubeh<br />
Eisner, David<br />
Endoh, Masao<br />
Eng, Calvin<br />
Engler, Robert<br />
Entman, Mark<br />
Escande, Denis<br />
Eskin, Suzanne<br />
Esler, Murray<br />
Etingin, Orli R.<br />
Ezekowitz, Michael<br />
Fabia<strong>to</strong>, Alexandre<br />
Fagin, James<br />
Fallon, John<br />
Fanburg, Barry L.<br />
Fanestil, Darrell D.<br />
Fanestil, David<br />
Faraci, Frank<br />
Farber, Harrison<br />
Faxon, David<br />
Fedida, David<br />
Feher, Joseph J.<br />
Feigl, Eric<br />
Feinstein, Steven<br />
Felder, Robert B.<br />
Feldman, Arthur<br />
Feneley, Michael P.<br />
Ferguson, Donald G.<br />
Ferrans, Vic<strong>to</strong>r J.<br />
Feuerstein, Giora<br />
Fingerle, Jurgen<br />
Fink, Gregory<br />
Fishman, Donald<br />
Fishman, Glenn I.<br />
Fishman, Mark C.<br />
Fitzgerald, Garrett A.<br />
Flabahan, Nicholas<br />
Flaherty, John T.<br />
Fleischer, Sidney<br />
Fletcher, J. Raymond<br />
Folkow, Bjorn U.G.<br />
Folts, John D.<br />
Foster, Robert E. II<br />
Fox, Paul<br />
Fozzard, Harry<br />
Francis, Gary S.<br />
Franzblau, Carl<br />
Freeman, Gregory<br />
Frizzell, Raymond A.<br />
Fuster, Valentin<br />
Gaasch, William<br />
Gallagher, Kim<br />
Galper, Jonas B.<br />
Ganten, Detlev<br />
Ganz, Peter<br />
George, Sam<br />
Gerritsen, Mary<br />
Gettes, Leonard<br />
Gewirtz, Henry<br />
Ghai, Geetha<br />
Giles, Wayne<br />
1539
1540 <strong>Circulation</strong> <strong>Research</strong> Vol 71, No 6 December 1992<br />
Gilmour, Robert<br />
Glagov, Seymour<br />
Glass, Leon<br />
Glembotski, Chris<br />
Glossman, Hartmut<br />
Glower, Donald<br />
Goldsmith, Samuel<br />
Goodenough, Daniel A.<br />
Gordon, Albert<br />
Goresky, Carl A.<br />
Gorman, Mark<br />
Gotlieb, Avrum<br />
Gould, K. Lance<br />
Graham, Robert M.<br />
Granger, D. Neil<br />
Grant, Augustus 0.<br />
Griendling, Kathy K.<br />
Griggs, Douglas M.<br />
Gross, Garrett J.<br />
Gross, Richard<br />
Gruetter, Carl A.<br />
Gurtner, Gail H.<br />
Gutterman, David<br />
Guy<strong>to</strong>n, John<br />
Gwathmey, Judith K.<br />
Haberland, Margaret<br />
Hageman, Gilbert R.<br />
Hajjar, David P.<br />
Hales, Charles<br />
Hamet, Pavel<br />
Hammond, H. Kirk<br />
Hamrell, Burt B.<br />
Hanley, Rochelle<br />
Harder, David R.<br />
Harker, Lawrence<br />
Harrison, David G.<br />
Hartzell, Charles<br />
Hartzell, Chris<br />
Harvey, Robert<br />
Hasebe, Naoyuki<br />
Hathaway, David<br />
Haworth, Robert A.<br />
Haworth, Sheila Glennis<br />
Hearse, David<br />
Heesch, Cheryl<br />
Heistad, Donald D.<br />
Henderson, Andrew H.<br />
Henry, Philip D.<br />
Hershkowitz, Ahvie<br />
Herskowitz, Ahvie<br />
Heusch, Gerd<br />
Heyndrickx, Guy<br />
Higgins, Charles<br />
Hilgemann, Donald<br />
Hintze, Thomas<br />
Hittinger, Luc<br />
Hoffman, Brian F.<br />
Hoffman, Julian I.E.<br />
Hollenberg, Norman<br />
Hori, Masatsuga<br />
Horwitz, Lawrence<br />
Houser, Stephen<br />
Housmans, Phillippe A.<br />
Huber, Sally Ann<br />
Hume, Joseph R.<br />
Hunter, William<br />
Husain, Ahsan<br />
Ideker, Raymond E.<br />
Ignarro, Louis J.<br />
Ihara, Tadashi<br />
Ingelfinger, Julie<br />
Ingels, Neil B.<br />
Intaglietta, Marcos<br />
Isner, Jeffrey M.<br />
Izumo, Seigo<br />
Jacobus, William E.<br />
Jaffe, Eric A.<br />
Jalife, Jose<br />
Jan, Lily<br />
Janicki, Joseph<br />
Janse, Michael J.<br />
January, Craig<br />
Jarmakani, Jay M.<br />
Jennings, Robert<br />
Johns, Roger A.<br />
Johnson. Paul C.<br />
Joho, Rolf<br />
Jones, Larry R.<br />
Joyner, Ronald W.<br />
Joyner, William L.<br />
Kadowitz, Philip<br />
Kaley, Gabor<br />
Karlinger, Joel S.<br />
Kass, David<br />
Kass, Robert S.<br />
Katusic, Zvonimir<br />
Kaul, Senjiu<br />
Keiser, Lana<br />
Kelly, Ralph<br />
Kenny, John<br />
Keung, Edmund C.<br />
Kirby, Margret<br />
Kirchheim, Hartmut R.<br />
Kiuchi, Kaname<br />
Klassen, Gerald A.<br />
Kleber, Andre G.<br />
Klitzner, Thomas<br />
Kloner, Robert A.<br />
Knight, Delvin<br />
Knowl<strong>to</strong>n, Kirk<br />
Kocher, Olivier<br />
Koller, Akos<br />
Komamura, Kazuo<br />
Kon<strong>to</strong>s, Hermes A.<br />
Korner, Paul<br />
Kraus, William E.<br />
Kroll, Keith<br />
Kroll, Michael H.<br />
Kung, Ching<br />
Kuo, L.<br />
Kurachi, Yoshihisa<br />
Kurz, Michael<br />
Kuschinsky, Wolfgang<br />
LaBarbera, M.<br />
Lacerda, Anthony<br />
Lagunoff, David<br />
Laine, Glen A.<br />
Lal, Ratneshwar<br />
Lamping, Kathryn<br />
Lamuraglia, Glenn<br />
Langer, Glenn A.<br />
Langille, B. Lowell<br />
Lanier, Steven<br />
LaNoue, Kathryn F.<br />
Laurindo, Francisco R.M.<br />
Lavallee, Michel<br />
Lawrence, John<br />
Lederer, W. Jonathan<br />
Lee, Hon Chi<br />
Lee, Richard<br />
Lefer, Allan M.<br />
Lefer, David<br />
Lefkowitz, Robert J.<br />
Leinwand, Leslie<br />
Lesch, Michael<br />
Levi, Rober<strong>to</strong><br />
Levin, R.I.<br />
Levitsky, Sidney<br />
Levy, Matthew N.<br />
Lewandowski, Douglas<br />
Lewicki, John A.<br />
LeWinter, Martin M.<br />
Lewis, M.J.<br />
Liang, Bruce<br />
Liang, Chang-seng<br />
Liao, James K.<br />
Liau, Gene<br />
Libby, Peter<br />
Liedke, A. James<br />
Lindpainter, Klaus<br />
Linehan, John H.<br />
Lipowski, Herbert H.<br />
Little, William<br />
Lokhandwala, Mastafa F.<br />
Lombardi, Federico<br />
Longhurst, John C.<br />
Lopaschuk, Gary D.<br />
Lorell, Beverly<br />
Loscalzo, Joseph<br />
Loutzenhiser, Rodger<br />
Lowenstein, Edward<br />
Lucchesi, Benedict R.<br />
Lucinskas, Francis W.<br />
Lucinskas, William<br />
Ludbrook, John<br />
Luscher, Thomas F.<br />
Lux, Robert<br />
Lynch, Carmel<br />
Lynch, Kevin<br />
Mackenzie, Eric T.<br />
Mahdavi, Vijak<br />
Majesky, Mark W.<br />
Makielski, Jonathan C.<br />
Malik, Asrar<br />
Malik, Kafait U.<br />
Malliani, Alber<strong>to</strong><br />
Mandell, Gerald<br />
Marban, Eduardo<br />
Marsden, Philip A.<br />
Marsh, Donald J.<br />
Marsh, James<br />
Martins, James B.<br />
Mayhan, William<br />
McCord, Joe M.<br />
McDonald, Terry<br />
McEver, Roger P.<br />
McGiff, John C.<br />
McMillin, Jeanie B.<br />
McMurtry, Ivan F.<br />
Medford, Russell M.<br />
Meissner, Gerhard<br />
Mendelsohn, Michael A.<br />
Meredith, Stephen C.<br />
Messina, Edward<br />
Michaels, Donald C.<br />
Michel, Thomas<br />
Miller, Richard J.<br />
Miller, Virginia<br />
Milnor, William<br />
Mirsky, Israel<br />
Mitzner, Wayne<br />
Moncada, Salva<strong>to</strong>re<br />
Morad, Martin<br />
Moreland, Robert S.<br />
Morgan, Howard E.<br />
Morgan, James P.<br />
Morgan, Kathleen<br />
Moss, Richard L.<br />
Mulieri, Louis<br />
Muller, James<br />
Muntz, Kathryn Howe<br />
Murphy, Elizabeth A.<br />
Murphy, Richard A.<br />
Murray, John<br />
Murray, Paul A.<br />
Murry, Charles<br />
Musch, Timothy<br />
Myerberg, Robert J.<br />
Nabel, Elizabeth<br />
Nakazawa, Mako<strong>to</strong><br />
Navab, Mahamad<br />
Neer, Eva<br />
Nelson, Mark T.<br />
Nerbonne, Jeanne M.<br />
Neubauer, Stefan<br />
Nichols, Colin<br />
Nichols, Wilmer W.<br />
Nilsson, Jan<br />
Noordergraff, Abraham<br />
Oates, John<br />
Olson, Don<br />
Olsson, Ray A.<br />
Oparil, Suzanne<br />
Osborn, Jeffrey<br />
Osol, George<br />
Owens, Gary K.<br />
O'Rourke, Brian<br />
O'Rourke, Michael F.<br />
Pagani, Massimo<br />
Page, Ernest<br />
Palade, George E.<br />
Palmer, Richard M.J.<br />
Panteley, George A.<br />
Parthasarathy, Sampath<br />
Pasipoularides, Ares<br />
Patrick, Thomas<br />
Patterson, Randolph E.<br />
Pearson, Jeremy<br />
Periasamy, Muthu<br />
Persson, Pontus B.<br />
Pertsov, Arcady<br />
Pfeffer, Marc A.<br />
Phan, Sem H.<br />
Pierce, Grant N.<br />
Pilking<strong>to</strong>n, Theodore<br />
Pledger, W.<br />
Pohl, Ulrich<br />
Pohost, Gerald M.
Polverini, Peter J.<br />
Port, J. David<br />
Potter, Erica<br />
Pouleur, Hubert G.<br />
Pratt, Raymond D.<br />
Pressler, Mil<strong>to</strong>n<br />
Pries, A.R.<br />
Przyklenk, Karin<br />
Qu, Yushing<br />
Quilley, John<br />
Raberger, G.<br />
Rabinovitch, Marlene<br />
Rasmussen, Randall<br />
Rea, Robert<br />
Reeves, John T.<br />
Reimer, Keith<br />
Reneman, Richard<br />
Renken, Eugene<br />
Reynolds, R.<br />
Riley, David<br />
Robbins, Jeffrey<br />
Roberge, Fernand A.<br />
Roberts, Robert<br />
Robinson, Richard<br />
Roden, Daniel<br />
Roeske, William<br />
Romans, Richard J.<br />
Rosen, Michael R.<br />
Roskoski, Robert<br />
Rothblum, Lawrence<br />
Rothe, Carl F.<br />
Roulau, Jean<br />
Rousseau, Eric C.<br />
Rovet<strong>to</strong>, Michael J.<br />
Rowell, Loring<br />
Rubanyi, Gabor M.<br />
Rudolf, Abraham<br />
Ruggieri, Zaverio<br />
Ryan, Una S.<br />
Sachs, Fred<br />
Saffitz, Jeffrey E.<br />
Sahn, David<br />
Salama, Guy<br />
Samarel, Allen M.<br />
Sane, David<br />
Sanguinetti, Michael<br />
Santamore, William P.<br />
Sasayama, Shigetake<br />
Sassard, Jean<br />
Saul, Philip<br />
Savard, Pierre<br />
Savembock, Ian<br />
Schafer, Andrew<br />
Schaffer, Stephen W.<br />
Schaper, Jutta<br />
Schaper, Wolfgang<br />
Schiffrin, Ernes<strong>to</strong> L.<br />
Schilling, William P.<br />
Schima, H.<br />
Schmid, Philip G.<br />
Schmid-Schoenbein, Geert<br />
Schmitz, Wilhelm<br />
Schneider, Michael<br />
Schuessler, Richard B.<br />
Schultz, Harold D.<br />
Schuschke, Dale<br />
Schwaiger, Markus<br />
Schwartz, David<br />
Schwartz, Gregory G.<br />
Schwartz, Ketty<br />
Schwartz, Peter J.<br />
Schwartz, Rochelle<br />
Schwartz, Stephen M.<br />
Schwinn, Debra A.<br />
Scicli, Guillermo<br />
Seagard, Jeanne L.<br />
Sedor, John<br />
Seidman, Christine<br />
Sen, Subha<br />
Seymour, Anne Marie<br />
Shannon, Rick<br />
Shasby, Michael<br />
Sheehan, Florence H.<br />
Sheldon, R.S.<br />
Shen, You Tang<br />
Shenolikar, Shirish<br />
Shepherd, John T.<br />
Sheu, Shey-Shing<br />
Shibata, Erwin<br />
Silverman, Howard<br />
Simonson, Maria<br />
Simpson, Paul<br />
Sinaway, Larry<br />
Singer, Harold<br />
Slakey, Linda<br />
Smith, Jeff<br />
Smith, Thomas W.<br />
Snyders, Dirk<br />
Soderling, Thomas R.<br />
Solaro, John<br />
Spach, Madison S.<br />
Spears, James Richard<br />
Spray, David<br />
Stambler, Bruce<br />
Starmer, C. Frank<br />
Steenbergen, Charles<br />
Stein, Paul<br />
Steinberg, Susan<br />
Stemerman, Michael B.<br />
Stephenson, Larry<br />
Stern, Michael<br />
Stiles, Gary L.<br />
Stimers, Joseph<br />
S<strong>to</strong>rch, Judith<br />
Strauss, Harold C.<br />
Strauss, Ludwig G.<br />
Stuhmer, Walter<br />
Suga, Hiroyuki<br />
Sunagawa, Kenji<br />
Sys, Stanislas<br />
Szabo, Gabor<br />
Taccardi, Bruno<br />
Taegtmeyer, Heinrich<br />
Tanaka, Hiroyuki<br />
Taubman, Mark<br />
Taylor, Anne<br />
Taylor, Aubrey E.<br />
Ten Eick, Robert E.<br />
ter Keurs, Henk<br />
Terracio, Louis<br />
Thames, James<br />
Thames, Marc D.<br />
Thomas, James<br />
Timmermans, Pieter<br />
Tobacman, Larry S.<br />
Tobian, Louis<br />
Toda, Noboru<br />
Tomanek, Robert<br />
Tomaselli, Gordon<br />
Topol, Eric J.<br />
Toyo-oka, Teruhiko<br />
Traystman, Richard J.<br />
Truskey, George<br />
Tseng, Gea-Ny<br />
Tucker, Vicki L.<br />
Valeri, Robert<br />
Vallee, Bert L.<br />
Van Bilsen, Marc<br />
Van Breemen, Cornelis<br />
van der Vusse, Ger J.<br />
Vanhoutte, Paul<br />
Vatner, Dorothy<br />
Vatner, Stephen<br />
<strong>Acknowledgment</strong> <strong>to</strong> <strong>Reviewers</strong> 1541<br />
Vaughn, Douglas<br />
Veenstra, Richard<br />
Verbeuren, Tony J.M.<br />
Verrier, Richard<br />
Vic<strong>to</strong>r, Ronald G.<br />
Vlahakes, Gus<br />
Vonharsdorf, Rudi<br />
Waldo, Albert L.<br />
Wallwork, James<br />
Walsh, Richard<br />
Ware, J. Anthony<br />
Warner, Margaret<br />
Wasserstrom, Andrew<br />
Webb, R. Clin<strong>to</strong>n<br />
Webster, Keith A.<br />
Weglicki, William B.<br />
Weisfeldt, Myron<br />
Weiss, James<br />
Weiss, Robert G.<br />
Weksler, Babette B.<br />
Westerhof, Nicolaas<br />
White, Howard D.<br />
Whor<strong>to</strong>n, A. Richard<br />
Wier, Gil<br />
Wight, Tom<br />
Wikman-Coffelt, Joan<br />
Wikswo, John P.<br />
Wilders, Ronald<br />
Wilkes, Barry<br />
Willerson, James T.<br />
Williams, R. Sanders<br />
Wilson, John<br />
Winegrad, Saul<br />
Winquist, Raymond J.<br />
Wit, Andrew L.<br />
Wolfe, Robert<br />
Wolin, Michael<br />
Woodcock, Elizabeth<br />
Worcel, Manuel<br />
Wurster, Robert D.<br />
Yellin, Edward<br />
Yin, Frank<br />
Young, Lawrence<br />
Young, Mark<br />
Zelis, Robert F.<br />
Zemel, Michael B.<br />
Zile, Michael<br />
Zipes, Douglas<br />
Zucker, Irving<br />
Zweifach, Bejamine W.
Abdelmeguid AE, 1049<br />
Adachi S, 1242<br />
Ahn HY, 951<br />
Akai K, 912<br />
Akata T, 859<br />
Akita H, 1410<br />
Alexander LD, 1324<br />
Alexander RW, 776<br />
Allen DG, 58<br />
Allen JC, 1294<br />
Allen P, 18<br />
Allen PD, 9<br />
Ambrosio G, 1447<br />
Anderson DC, 1518<br />
Ando H, 481<br />
Anumonwo JMB, 229, 821<br />
Anversa P, 346, 1379<br />
Anyukhovsky EP, 526<br />
Apstein CS, 401<br />
Arai H, 34<br />
Araki H, 577<br />
Arentzen CE, 535<br />
Arisi G, 840<br />
Arnsdorf MF, 737<br />
Ashikawa K, 912<br />
Ashraf M, 96<br />
Attawia MA, 40<br />
Avkiran M, 1429<br />
Badimon JJ, 769<br />
Baird A, 251<br />
Baker R, 732<br />
Barr RC, 260<br />
Barrett EJ, 393<br />
Bashore TM, 1174<br />
Bassett AL, 87<br />
Baulieu EE, 503<br />
Bauman RP, 27<br />
Beckmann J, 3<br />
Bellot<strong>to</strong> D, 106<br />
Bennardini F, 288<br />
Bennett PB, 732<br />
Bentivegna LA, 1334<br />
Benzi RH, 567<br />
Berger PJ, 443<br />
Bernstein D, 1465<br />
Bevan JA, 339<br />
Beyer EC, 1277<br />
Bialecki RA, 1008<br />
Bienvenu K, 906<br />
Bigaud M, 1185<br />
Biro S, 640<br />
Bishara M, 1294<br />
Blank PS, 870<br />
Blank RS, 1525<br />
Bloor CM, 1490<br />
Boineau JP, 1254<br />
Bonvalet J-P, 503<br />
Bouchard RA, 673<br />
Boyden PA, 1390<br />
Brand T, 1351<br />
Braun M, 1305<br />
Brecher P, 1341<br />
Brillantes A-M, 18<br />
Bromberg BI, 1254<br />
Bruno S, 1379<br />
Author Index<br />
Volume 71, July-December 1992<br />
Brusilow SW, 1220<br />
Budanova OP, 526<br />
Buja LM, 106<br />
Cabo C, 260<br />
Callewaert G, 808<br />
Cambien F, 3<br />
Capasso JM, 346, 1379<br />
Capogrossi MC, 870<br />
Cappelli-Bigazzi M, 1447<br />
Carabello BA, 1472<br />
Carmeliet E, 808<br />
Carrier L, 3<br />
Carrier M, 1159<br />
Carroll SM, 1490<br />
Carrozza JP Jr, 1334<br />
Casado MA, 943<br />
Casscells W, 251<br />
Catravas JD, 923<br />
Chacko VP, 1111<br />
Chapman GD, 27<br />
Charles R, 240<br />
Cheng W, 1379<br />
Chesebro JH, 769<br />
Chiariello M, 1447<br />
Chiesi M, 288<br />
Chobanian A, 1341<br />
Cinca J, 1131<br />
Clamp L, 1472<br />
Coceani F, 320<br />
Cohen D, 3<br />
Colucci WS, 1008<br />
Condorelli M, 1447<br />
Connelly CM, 401<br />
Cook MA, 1101<br />
Coronel R, 1131<br />
Corradi C, 840<br />
Cortese R, 346<br />
Couraud JY, 1526<br />
Cox JL, 1254<br />
Cragoe EJ Jr, 1294, 1314<br />
Crawford FA, 174<br />
Culp SC, 27<br />
Dahl DM, 393<br />
Dai J, 970<br />
Darzynkiewicz Z, 1379<br />
de Jong F, 240<br />
De Micheli A, 471<br />
de Tombe PP, 414<br />
DeFreyte G, 1472<br />
Deitiker PR, 1404<br />
Dellsperger KC, 120<br />
Delmar M, 229, 821<br />
Desnos M, 3<br />
Desper JS, 27<br />
Deussen A, 590<br />
Dichek DA, 1508<br />
Doetschman T, 1021<br />
Doshi R, 1465<br />
Drew JS, 1067<br />
Dreyer WJ, 1518<br />
Dubey RK, 1143<br />
Dubourg 0, 3<br />
Dufour C, 3<br />
Duncker DJ, 1351<br />
1543<br />
Dunham B, 229<br />
Dunning AJ, 1361<br />
Eastham CL, 120<br />
Egashira K, 435<br />
Eghbali M, 831<br />
Eid H, 40<br />
Elizondo E, 1088<br />
Ellefson RD, 769<br />
Entman ML, 1518<br />
Epstein HF, 1404<br />
Epstein M, 471<br />
Epstein SE, 640<br />
Espiner EA, 1501<br />
Esposi<strong>to</strong> B, 932<br />
Faber JE, 188<br />
Fagin JA, 646<br />
Farber HW, 782<br />
Farman N, 503<br />
Farris J, 251<br />
Farrugia E, 1153<br />
Faure L, 3<br />
Fedida D, 673<br />
Feher JJ, 1049<br />
Ferguson DG, 1021<br />
Fernandez-Alfonso MS, 943<br />
Ferriere M, 3<br />
Fiolet JWT, 1131<br />
Flameng W, 1123<br />
Fleidervish IA, 1231<br />
Fleischmann KE, 1351<br />
Forrester JS, 646<br />
Forster H, 471<br />
Fougerousse F, 3<br />
Framp<strong>to</strong>n C, 1501<br />
Fu Y-M, 640<br />
Fujii M, 120<br />
Fukunaga K, 1422<br />
Fulbright BM, 174<br />
Furukawa T, 535, 1242<br />
Fuster V, 769<br />
Gaballa MA, 145<br />
Gabbasov ZA, 218<br />
Galifianes M, 1213<br />
Gambassi G, 870<br />
Gammon RS, 27<br />
Ganim JR, 1021<br />
Ganz P, 776<br />
Gasc J-M, 503<br />
Gelband CH, 745<br />
Geng Y, 1268<br />
Giachelli CM, 759<br />
Giannella-Ne<strong>to</strong> D, 646<br />
Goings G, 159<br />
Goknur AB, 210<br />
Goldman G, 82<br />
Goldman S, 145<br />
Golino P, 1447<br />
Gonzalez AM, 251<br />
Gonzalez R, 943<br />
Gordon AM, 984<br />
Grady EF, 1482<br />
Graham RM, 1185<br />
Granger DN, 906<br />
Grayson TM, 1254<br />
Griffin CA, 1482<br />
Gross SS, 992<br />
Grossman W, 1334<br />
Grupp I, 1021<br />
Gu H, 1314<br />
Guideri G, 346<br />
Gutterman DD, 960<br />
Hagler HK, 106<br />
Haigney MCP, 547<br />
Halliwell B, 295<br />
Hama N, 34<br />
Hamamori Y, 1410<br />
Hamp<strong>to</strong>n TG, 1174<br />
Han DKM, 711<br />
Hannon JD, 984<br />
Hansson GK, 1268<br />
Hara Y, 1457<br />
Harasawa Y, 414<br />
Harker LA, 1285<br />
Harmsen E, 1059<br />
Harrison DG, 120<br />
Harrison JK, 1174<br />
Hart PJ, 1002<br />
Hartz RS, 535<br />
Harwalkar VA, 1067<br />
Hasebe N, 423, 1185<br />
Hauer RNW, 1361<br />
Haworth RA, 210<br />
Hayakawa H, 1039<br />
Hayashi Y, 435<br />
Hayashida K, 481<br />
Hearse DJ, 1213<br />
Hechtman HB, 82<br />
Heidbuchel H, 808<br />
Hempel DM, 1185<br />
Hendrikx M, 1123<br />
Hengstenberg C, 3<br />
Henrion D, 339<br />
Herrmann RA, 883<br />
Heym C, 1526<br />
Hiraoka M, 585, 1242<br />
Hirata K, 1410<br />
Hirata T, 1220<br />
Hirata Y, 1039<br />
Hiratsuka E, 1031<br />
Hiroe M, 1242<br />
Hittinger L, 423<br />
Holme E, 1268<br />
Holycross BJ, 1525<br />
Homeister JW, 303<br />
Hori M, 558<br />
Horowitz B, 1002<br />
Hosoda K, 34<br />
Hu J, 174<br />
Huang BS, 1059<br />
Huang S, 1465<br />
Hume JR, 745, 1002<br />
Hunter WC, 414<br />
Ibuki C, 1429<br />
Ihara T, 423<br />
Ikeda U, 1457<br />
Ikram H, 1501<br />
Illiano S, 137
1544 <strong>Circulation</strong> <strong>Research</strong> Vol 71, No 6 December 1992<br />
Imamura S, 1031<br />
Imamura T, 357<br />
Imura H, 34, 614<br />
Inoue M, 558, 577<br />
Inoue N, 1410<br />
Ishida Y, 620<br />
Ishihara K, 1472<br />
I<strong>to</strong> H, 1242<br />
I<strong>to</strong>h T, 70<br />
Iwai K, 558<br />
Izumo S, 9, 18<br />
Jalife J, 229<br />
Janse MJ, 240, 1131, 1361<br />
Jasper JR, 1465<br />
Jeck CD, 1390<br />
Jia H, 535<br />
Joly GA, 331<br />
Jougasaki M, 577, 614<br />
Junquero DC, 1088<br />
Kadambi V, 1021<br />
Kahn AM, 1294<br />
Kahn ML, 1508<br />
Kaley G, 790<br />
Kalinyak JE, 1482<br />
Kamada T, 558<br />
Kaminski PM, 720<br />
Kamitani T, 1457<br />
Kamm RD, 850<br />
Kamyar A, 646<br />
Kanatsuka H, 912<br />
Kanazawa S, 1472<br />
Kangawa K, 1039<br />
Kanno M, 1441<br />
Kaplan P, 1123<br />
Karlinsky JB, 782<br />
Karmazyn M, 1101<br />
Kass DA, 490<br />
Katayama A, 106<br />
Kawahara Y, 620<br />
Kawakami K, 1457<br />
Kawano S, 585<br />
Kawasaki H, 357<br />
Kawase T, 951<br />
Kelly RA, 40<br />
Kelly RP, 490<br />
Kenyon JL, 1002<br />
Khoury DS, 511<br />
Kieval RS, 127<br />
Kim HW, 1021<br />
Kimura M, 1031<br />
Kimura S, 87<br />
Kingma JH, 1361<br />
Kishimo<strong>to</strong> I, 34<br />
Kitabatake A, 558<br />
Kitakaze M, 558<br />
Kiuchi K, 1185<br />
Kleber AG, 460<br />
Klein JL, 776<br />
Klimaschewski L, 1526<br />
Kloner RA, 1165<br />
Kluft C, 385<br />
Kobzik L, 82<br />
Koehler RC, 1220<br />
Kohmo<strong>to</strong> 0, 1039<br />
Koide M, 620<br />
Kojima M, 1039<br />
Kojima T, 1457<br />
Kolbeck-Ruhmkorff C, 451<br />
Koller A, 790<br />
Komajda M, 3<br />
Komamura K, 423<br />
Komaru T, 912<br />
Komatsu Y, 34<br />
Kranias EG, 1021<br />
Kroeker TS, 1078<br />
Kroll K, 590<br />
Kugiyama K, 614, 1422<br />
Kummer W, 1526<br />
Kuntz RE, 1334<br />
Kupfer J, 646<br />
Kuriyama H, 70, 859<br />
Kusuoka H, 1111<br />
Laher I, 339<br />
Lakatta EG, 547, 605, 870<br />
Lal R, 737<br />
Lam JYT, 769<br />
Lamers WH, 240<br />
Lamp ST, 1324<br />
Lamping KG, 120<br />
Lankat-Buttgereit B, 451<br />
Larson DM, 40<br />
Larson TS, 1153<br />
Laurier J, 365<br />
Lavall&e M, 365<br />
Lee JA, 58<br />
Lee RT, 850<br />
Lee SW, 1508<br />
Leenen FHH, 1059<br />
Leinwand LA, 1<br />
Leppla DC, 201<br />
Lerch R, 567<br />
Levesque PC, 1002<br />
Levi R, 992<br />
Levy MN, 898<br />
Li P, 346, 1379<br />
Liau G, 711<br />
Libby P, 1<br />
Liedtke AJ, 689<br />
Lim CS, 27<br />
Litwin SE, 797<br />
Lockhart JC, 1153<br />
Lombes M, 503<br />
Longhurst JC, 295<br />
Loree HM, 850<br />
Lucchesi BR, 303<br />
Luo W, 1021<br />
Lux RL, 840<br />
Maamarbachi 0, 365<br />
Macchi E, 840<br />
Magnet A, 1490<br />
Majesky MW, 759, 1285<br />
Makielski JC, 1231<br />
Malhotra A, 346<br />
Malik AB, 1015<br />
Malinauskas RA, 883<br />
Mamuya W, 1341<br />
Manders WT, 423<br />
Manoukian SV, 776<br />
Mansell AL, 701<br />
Marban E, 1111<br />
Marin J, 943<br />
Marks AR, 18<br />
Martyn DA, 984<br />
Marumo F, 1242<br />
Maseri A, 385<br />
Matsuda Y, 1410<br />
Matsuo H, 1039<br />
Matsuoka H, 1039<br />
Matsuoka R, 1031<br />
Mattheussen M, 1123<br />
Mayer B, 1526<br />
McAteer AL, 701<br />
McCarty NA, 1294<br />
McFalls EO, 1351<br />
Medford RM, 1457<br />
Meij JTA, 970<br />
Merval R, 932<br />
Messina EJ, 790<br />
Meszdros J, 376<br />
Michael LH, 1518<br />
Miller FJ, 960<br />
Minamino N, 1039<br />
Miyamo<strong>to</strong> E, 1422<br />
Miyata H, 547, 605<br />
Mombouli J-V, 137<br />
Momma K, 1314<br />
Moore EN, 127<br />
Moorman AFM, 240<br />
Moreland RS, 951<br />
Moreland S, 951<br />
Morgan DA, 960<br />
Morgan JP, 631, 797, 1334<br />
Morley GE, 821<br />
Mubagwa K, 1123<br />
Mukherjee R, 174<br />
Mukoyama M, 34<br />
Muntz KH, 51<br />
Muramo<strong>to</strong> J, 577<br />
Murohara T, 1422<br />
Mu<strong>to</strong> S, 1457<br />
Myerburg RJ, 87<br />
Nabel EG, 776<br />
Nadal-Ginard B, 1<br />
Nagano K, 1457<br />
Nagano T, 451<br />
Nagao T, 137<br />
Nagatsu M, 1472<br />
Nakagawa 0, 34<br />
Nakamura F, 585<br />
Nakamura M, 435, 481<br />
Nakanishi T, 1314<br />
Nakano K, 1472<br />
Nakao K, 34, 614<br />
Nakashima M, 859<br />
Nakaya H, 1441<br />
Nattel S, 271<br />
Navran SS, 1294<br />
Nayak RC, 40<br />
Nellis SH, 689<br />
Neumann JC, 1021<br />
Ngoy S, 401<br />
Nguyen T, 1518<br />
Nikashin AV, 526<br />
Nishi K, 577<br />
Nishigaki K, 188<br />
Nishimura J, 951<br />
Nitta J, 1242<br />
Noma M, 481<br />
Nuno DW, 120<br />
Oblin M-E, 503<br />
Ogawa Y, 34<br />
Oguchi A, 1457<br />
Ohgushi M, 1422<br />
Ohyanagi M, 188<br />
Okazaki H, 1285<br />
O'Neil RG, 1294<br />
Onodera T, 96<br />
Opthof T, 240, 1131<br />
Orekhov AN, 218<br />
Overbeck HW, 1143<br />
Ovize M, 1165<br />
Owens GK, 1525<br />
Padua R, 970<br />
Page E, 159<br />
Page P, 271<br />
Panagia V, 970<br />
Pare R, 365<br />
Pareja A, 943<br />
Parent R, 365<br />
Park KH, 992<br />
Pasipoularides AD, 1174<br />
Pastan I, 640<br />
Paterson IS, 82<br />
Patrick TA, 423<br />
Peach MJ, 1525<br />
Pelletier CL, 1159<br />
Philippin B, 1526<br />
Pipkin AC, 701<br />
Pirola CJ, 646<br />
Po S, 732<br />
Ponniah S, 1021<br />
Ponte A, 943<br />
Popov EG, 218<br />
Preissler U, 1526<br />
Proc<strong>to</strong>r KG, 720<br />
Przyklenk K, 1165<br />
Quax PHA, 385<br />
Ragni M, 1447<br />
Rauner D, 393<br />
Raya TE, 145<br />
Reed RK, 978<br />
Reidy MA, 759<br />
Renstrom B, 689<br />
Renwick GH, 776<br />
Richards AM, 1501<br />
Roberts R, 1404<br />
Roberts WL, 883<br />
Rodgers R, 1379<br />
Rodriguez-Mafias L, 943<br />
Rodt SA, 978<br />
Rosen MR, 526<br />
Rossen RD, 1518<br />
Rosenfeld RG, 646<br />
Rosenquist TH, 923<br />
Rounds S, 782<br />
Roy A, 1143<br />
Rubin K, 978<br />
Rubin LE, 992<br />
Rudy Y, 511<br />
Russell J, 906<br />
Russolillo E, 1447<br />
Ryan JW, 923<br />
Rybin VO, 526<br />
Sacrez A, 3<br />
Sai<strong>to</strong> Y, 614<br />
Sakakibara Y, 535<br />
Sanchez-Ferrer CF, 943<br />
Sa<strong>to</strong> H, 558<br />
Sa<strong>to</strong> K, 912<br />
Sa<strong>to</strong>h P, 303<br />
Sawanobori T, 1242<br />
Schambelan M, 1482<br />
Schaper W, 1351<br />
Schini VB, 331, 1088<br />
Schoen FJ, 401<br />
Schror K, 1305<br />
Schuessler RB, 1254<br />
Schwartz K, 3<br />
Schwartz SM, 759, 1285<br />
Scott-Burden T, 137, 1088<br />
Sechi LA, 1482<br />
Seguchi M, 1314<br />
Seidel CL, 1294<br />
Sekiguchi N, 912<br />
Selwyn AP, 776<br />
Sen L, 1008
Shafiq J, 70<br />
Sharifi B, 646<br />
Sharma HS, 1351<br />
Shelat H, 1294<br />
Shen Y-T, 423<br />
Shepro D, 82<br />
Sheriff DD, 414<br />
Shii K, 620<br />
Shim Y, 1174<br />
Shimada K, 1457<br />
Shirakami G, 34<br />
Siegall CB, 640<br />
Silverman HS, 547, 605<br />
Simard JM, 201<br />
Simon BR, 145<br />
Singer DH, 535<br />
SippensGroenewegen A, 1361<br />
Smirnov VN, 218<br />
Smith CW, 1518<br />
Smith E, 1008<br />
Smith TW, 40, 1008<br />
Smolich JJ, 443<br />
Snyders DJ, 732<br />
Sobenin IA, 218<br />
Soust M, 443<br />
Spaan JAE, 1200<br />
Spear JF, 127<br />
Speir E, 251, 640<br />
Spekhorst H, 1361<br />
Sperelakis N, 376<br />
Spero LA, 1174<br />
Sperti G, 385<br />
Spinale FG, 174<br />
Springhorn JP, 40<br />
Spurgeon HA, 870<br />
Stack RS, 27<br />
Stahl GL, 295<br />
Stein LA, 1067<br />
Stern MD, 547, 605<br />
Straley CA, 1174<br />
Strandness E, 1465<br />
Strauss HC, 1<br />
Stringfellow RG, 850<br />
Stuart JS, 1324<br />
Suga S, 34<br />
Sugama Y, 1015<br />
Sugimachi M, 481<br />
Sugimo<strong>to</strong> To, 1039<br />
Sugimo<strong>to</strong> Ts, 1039<br />
Sugiyama S, 1422<br />
Sun D, 790<br />
Sunagawa K, 481<br />
Suzuki E, 1039<br />
Suzuki S, 70<br />
Swain JL, 27<br />
Sweet IR, 590<br />
Taccardi B, 840<br />
Taguchi T, 357<br />
Takahashi H, 1220<br />
Takahashi T, 9, 18<br />
Takao A, 1031<br />
Takasaki K, 357<br />
Takashima S, 558<br />
Takemura G, 96<br />
Takenaka T, 471<br />
Takeshita A, 435<br />
Takishima T, 912<br />
Tamkun MM, 732<br />
Tanaka R, 174<br />
Tanaka T, 585<br />
Tanner V, 251<br />
Tedgui A, 932<br />
Ter<strong>to</strong>v VV, 218<br />
Thandroyen FT, 106<br />
Thompson MM, 1525<br />
Tohse N, 376, 1441<br />
Tomita M, 1472<br />
Tomoike H, 435<br />
Topouzis S, 923<br />
Trabka-Janik E, 229<br />
Traystman RJ, 1220<br />
Treasure CB, 776<br />
Tronc F, 1159<br />
Truskey GA, 883<br />
Tseng G-N, 657<br />
Tseng-Crank J, 657<br />
Tsuda T, 620<br />
Tsujino M, 1242<br />
Tsuruya Y, 1457<br />
Tunin R, 490<br />
Uemura N, 1185<br />
Undrovinas AI, 1231<br />
Upshaw-Earley J, 159<br />
Valeri CR, 82<br />
van Breemen C, 951<br />
van Hemel NM, 1361<br />
van Leeuwen RTJ, 385<br />
VanBavel E, 1200<br />
Vanhoutte PM, 137, 331, 1088<br />
Vatner DE, 1185<br />
Vatner SF, 1, 423, 1185<br />
Veenstra RD, 229, 1277<br />
Venkatesh N, 1324<br />
Verdouw PD, 1351<br />
Vereecke J, 808<br />
Vita JA, 776<br />
Vosberg H-P, 3<br />
Vybiral T, 1404<br />
Walker AM, 443<br />
Wang H-Z, 229, 1277<br />
Author Index 1545<br />
Wang J, 631<br />
Wang Y, 320, 912<br />
Wang Z, 271<br />
Warner MR, 1078<br />
Wasserstrom JA, 535<br />
Weiss JN, 1324<br />
Welbourn R, 82<br />
West GA, 201<br />
Westphale EM, 1277<br />
White FC, 1490<br />
Wiig H, 978<br />
Wilde AAM, 240<br />
Willerson JT, 106<br />
Williams CP, 1334<br />
Wilms-Schopman FJG, 1131<br />
Wittert GA, 1501<br />
Wolin MS, 790<br />
Wrzosek A, 288<br />
Xi H, 87<br />
Yamada A, 435<br />
Yamada M, 1410<br />
Yamamo<strong>to</strong> K, 1457<br />
Yan G-X, 460<br />
Yandle TG, 1501<br />
Yang T, 898<br />
Yao J, 831<br />
Yaroslavov AA, 218<br />
Yasue H, 614, 1422<br />
Yokoyama M, 620, 1410<br />
Young LH, 393<br />
Yu H, 1059<br />
Zierhut W, 451<br />
Zile MR, 174, 1472<br />
Zimmer H-G, 451<br />
Zipes DP, 1078
A<br />
A-type potassium channel<br />
Differential Effects of Elevating [K]O on Three Transient Outward<br />
Potassium Channels: Dependence on Channel Inactivation<br />
Mechanisms, 657<br />
Abnormal au<strong>to</strong>maticity<br />
Positive Chronotropic Responses Induced by a1-Adrenergic<br />
Stimulation of Normal and "Ischemic" Purkinje Fibers Have<br />
Different Recep<strong>to</strong>r-Effec<strong>to</strong>r Coupling Mechanisms, 526<br />
Acetylcholine<br />
Epicardial Coronary Artery Responses <strong>to</strong> Acetylcholine Are<br />
Impaired in Hypertensive Patients, 776<br />
Extracellular and Intracellular Actions of Adenosine and Related<br />
Compounds in the Reperfused Rat Intestine, 720<br />
Membrane-Bound Nucleoside Diphosphate Kinase Activity in<br />
Atrial Cells of Frog, Guinea Pig, and Human, 808<br />
Sequence of Excitation as a Fac<strong>to</strong>r in Sympathetic-Parasympathetic<br />
Interactions in the Heart, 898<br />
Acidic fibroblast growth fac<strong>to</strong>r<br />
In Vitro Effects of a Recombinant Toxin Targeted <strong>to</strong> the<br />
Fibroblast Growth Fac<strong>to</strong>r Recep<strong>to</strong>r on Rat Vascular Smooth<br />
Muscle and Endothelial Cells, 640<br />
Acidosis<br />
Changes in Extracellular and Intracellular pH in Ischemic<br />
Rabbit Papillary Muscle, 460<br />
Endothelin Reverses the Effects of Acidosis on the Intracellular<br />
Ca2' Transient and Contractility in Ferret Myocardium, 631<br />
Actin<br />
aB-Crystallin in Cardiac Tissue: Association With Actin and<br />
Desmin Filaments, 288<br />
Action potential duration<br />
Mechanism of Flecainide's Antiarrhythmic Action in Experimental<br />
Atrial Fibrillation, 271<br />
Activation shift<br />
Inward Sodium Current at Resting Potentials in Single Cardiac<br />
Myocytes Induced by the Ischemic Metabolite Lysophosphatidylcholine,<br />
1231<br />
Acute inflammation<br />
Blockade of ,31-Integrins in Skin Causes Edema Through Lowering<br />
of Interstitial Fluid Pressure, 978<br />
Adenine nucleotide metabolism<br />
Effects of Norepinephrine on the Oxidative Pen<strong>to</strong>se Phosphate<br />
Pathway in the Rat Heart, 451<br />
Adenosine<br />
Microvascular Sites and Mechanisms Responsible for Reactive<br />
Hyperemia in the Coronary <strong>Circulation</strong> of the Beating Canine<br />
Heart, 912<br />
Nitric Oxide Is a Media<strong>to</strong>r of Hypoxic Coronary Vasodilatation:<br />
Relation <strong>to</strong> Adenosine and Cyclooxygenase-Derived Metabolites,<br />
992<br />
ADP<br />
Extracellular and Intracellular Actions of Adenosine and Related<br />
Compounds in the Reperfused Rat Intestine, 720<br />
Product Inhibition of the Ac<strong>to</strong>myosin Subfraginent-1 ATPase in<br />
Skeletal, Cardiac, and Smooth Muscle, 1067<br />
a1-Adrenergic recep<strong>to</strong>rs<br />
Interaction Between Microvascular al- and a2-Adrenocep<strong>to</strong>rs<br />
and Endothelium-Derived Relaxing Fac<strong>to</strong>r, 188<br />
Mechanisms of a1-Adrenergic Vascular Desensitization in Conscious<br />
Dogs, 1185<br />
Transcriptional Regulation of Left Ventricular ,3-Adrenergic<br />
Recep<strong>to</strong>rs During Chronic Hypoxia, 1465<br />
Subject Index<br />
Volume 71, July-December 1992<br />
1546<br />
a1-Adrenocep<strong>to</strong>rs<br />
a1-Adrenocep<strong>to</strong>r Stimulation Enhances the Delayed Rectifier<br />
K' Current of Guinea Pig Ventricular Cells Through the<br />
Activation of Protein Kinase C, 1441<br />
Different Effects of a and /3-Adrenergic Stimulation on Cy<strong>to</strong>solic<br />
pH and Myofilament Responsiveness <strong>to</strong> Ca2' in Cardiac<br />
Myocytes, 870<br />
Mechanisms for the Positive Inotropic Effect of a1-Adrenocep<strong>to</strong>r<br />
Stimulation in Rat Cardiac Myocytes, 673<br />
3-Adrenergic recep<strong>to</strong>rs<br />
Au<strong>to</strong>radiographic Characterization of f-Adrenergic Recep<strong>to</strong>r<br />
Subtype in the Canine Conduction System, 51<br />
Cap<strong>to</strong>pril Enhances Intracellular Calcium Handling and p-Adrenergic<br />
Responsiveness of Myocardium From Rats With<br />
Postinfarction Failure, 797<br />
f-Adrenocep<strong>to</strong>rs<br />
Different Effects of a- and 83-Adrenergic Stimulation on Cy<strong>to</strong>solic<br />
pH and Myofilament Responsiveness <strong>to</strong> Ca2' in Cardiac<br />
Myocytes, 870<br />
Adult myocytes<br />
HCO3--Dependent Intracellular pH Regulation in the Premature<br />
Myocardium, 1314<br />
Aequorin<br />
Decreased Myofilament Responsiveness in Myocardial Stunning<br />
Follows Transient Calcium Overload During Ischemia and<br />
Reperfusion, 1334<br />
Endothelin Reverses the Effects of Acidosis on the Intracellular<br />
Ca2' Transient and Contractility in Ferret Myocardium, 631<br />
Afferent arterioles<br />
Impaired Myogenic Responsiveness of Renal Microvessels in<br />
Dahl Salt-Sensitive Rats, 471<br />
Afferents<br />
Hydrogen Peroxide-Induced Cardiovascular Reflexes: Role of<br />
Hydroxyl Radicals, 295<br />
Age-related changes<br />
Age-Related Changes in Fibronectin Expression in Spontaneously<br />
Hypertensive, Wistar-Kyo<strong>to</strong>, and Wistar Rat Hearts,<br />
1341<br />
Albumin concentration<br />
Albumin Transport Characteristics of Rat Aorta in Early Phase<br />
of Hypertension, 932<br />
Aldosterone<br />
Immunohis<strong>to</strong>chemical and Biochemical Evidence for a Cardiovascular<br />
Mineralocorticoid Recep<strong>to</strong>r, 503<br />
Aminoimidazole carboxamide riboside<br />
Extracellular and Intracellular Actions of Adenosine and Related<br />
Compounds in the Reperfused Rat Intestine, 720<br />
4-Aminopyridine<br />
Mechanisms for the Positive Inotropic Effect of a1-Adrenocep<strong>to</strong>r<br />
Stimulation in Rat Cardiac Myocytes, 673<br />
Ammonia<br />
Res<strong>to</strong>ration of Cerebrovascular CO2 Responsivity by Glutamine<br />
Synthesis Inhibition in Hyperammonemic Rats, 1220<br />
AMP<br />
Extracellular and Intracellular Actions of Adenosine and Related<br />
Compounds in the Reperfused Rat Intestine, 720<br />
Angioplasty<br />
Gene Transfer In<strong>to</strong> Coronary Arteries of Intact Animals With a<br />
Percutaneous Balloon Catheter, 27<br />
In Vitro Effects of a Recombinant Toxin Targeted <strong>to</strong> the<br />
Fibroblast Growth Fac<strong>to</strong>r Recep<strong>to</strong>r on Rat Vascular Smooth<br />
Muscle and Endothelial Cells, 640<br />
Angiotensin converting enzyme<br />
Influence of Vascular Smooth Muscle Heterogeneity on Angiotensin<br />
Converting Enzyme Activity in Chicken Embryonic<br />
Aorta and in Endothelial Cells in Culture, 923
Angiotensin I converting enzyme<br />
Potentiation of Endothelium-Dependent Relaxations <strong>to</strong> Bradykinin<br />
by Angiotensin I Converting Enzyme Inhibi<strong>to</strong>rs in<br />
Canine Coronary Artery Involves Both Endothelium-Derived<br />
Relaxing and Hyperpolarizing Fac<strong>to</strong>rs, 137<br />
Angiotensin II<br />
Angiotensin II Stimulates Two Myelin Basic Protein/Microtubule-Associated<br />
Protein 2 Kinases in Cultured Vascular<br />
Smooth Muscle Cells, 620<br />
Effect of Inhibition of Endopeptidase 24.11 on Responses <strong>to</strong><br />
Angiotensin II in Human Volunteers, 1501<br />
Time Course of Left Ventricular Function After Cardiac Denervation<br />
in Conscious Dogs, 365<br />
Angiotensin II recep<strong>to</strong>rs<br />
Characterization of Angiotensin II Recep<strong>to</strong>r Subtypes in Rat<br />
Heart, 1482<br />
Anoxia<br />
Relation of Mi<strong>to</strong>chondrial and Cy<strong>to</strong>solic Free Calcium <strong>to</strong><br />
Cardiac Myocyte Recovery After Exposure <strong>to</strong> Anoxia, 605<br />
Antiarrhythmic drugs<br />
Functional Expression of an Inactivating Potassium Channel<br />
Cloned From Human Heart, 732<br />
Mechanism of Flecainide's Antiarrhythmic Action in Experimental<br />
Atrial Fibrillation, 271<br />
Aorta<br />
Albumin Transport Characteristics of Rat Aorta in Early Phase<br />
of Hypertension, 932<br />
Influence of Vascular Smooth Muscle Heterogeneity on Angiotensin<br />
Converting Enzyme Activity in Chicken Embryonic<br />
Aorta and in Endothelial Cells in Culture, 923<br />
Aortic input impedance<br />
Effect of Reduced Aortic Compliance on Cardiac Efficiency and<br />
Contractile Function of In Situ Canine Left Ventricle, 490<br />
Ejection Load Changes in Aortic Stenosis: Observations Made<br />
After Balloon Aortic Valvuloplasty, 1174<br />
Arrhythmia mechanisms<br />
Mechanism of Flecainide's Antiarrhythmic Action in Experimental<br />
Atrial Fibrillation, 271<br />
Arrhythmias<br />
Gap Junctional Conductance in Ventricular Myocyte Pairs<br />
Isolated From Postischemic Rabbit Myocardium, 127<br />
Arterial Injury<br />
Cod Liver Oil Alters Platelet-Arterial Wall Response <strong>to</strong> Injury<br />
in Pigs, 769<br />
Arterial smooth muscle cells<br />
Cholesterol Increases the L-Type Voltage-Sensitive Calcium<br />
Channel Current in Arterial Smooth Muscle Cells, 1008<br />
Arterial wall<br />
Measurement of Endothelial Permeability <strong>to</strong> 1"I-Low Density<br />
Lipoproteins in Rabbit Arteries by Use of En Face Preparations,<br />
883<br />
Arterioles<br />
Interaction Between Microvascular al- and a2-Adrenocep<strong>to</strong>rs<br />
and Endothelium-Derived Relaxing Fac<strong>to</strong>r, 188<br />
Atherosclerosis<br />
Balloon Injury and Interleukin-1 ,3 Induce Nitric Oxide Synthase<br />
Activity in Rat Carotid Arteries, 331<br />
Cholesterol Increases the L-Type Voltage-Sensitive Calcium<br />
Channel Current in Arterial Smooth Muscle Cells, 1008<br />
Effects of Fibrous Cap Thickness on Peak Circumferential<br />
Stress in Model Atherosclerotic Vessels, 850<br />
Suppression of Endothelin-1 Secretion by Lysophosphatidylcholine<br />
in Oxidized Low Density Lipoprotein in Cultured Vascular<br />
Endothelial Cells, 614<br />
Three Types of Naturally Occurring Modified Lipoproteins<br />
Induce Intracellular Lipid Accumulation Due <strong>to</strong> Lipoprotein<br />
Aggregation, 218<br />
ATP ATP Dependence of Calcium Uptake by the Na-Ca Exchanger<br />
of Adult Heart Cells, 210<br />
Extracellular and Intracellular Actions of Adenosine and Related<br />
Compounds in the Reperfused Rat Intestine, 720<br />
Subject Index 1547<br />
ATP-sensitive K' channel<br />
Activation of ATP-Sensitive K' Channels by Cromakalim: Effects<br />
on Cellular K' Loss and Cardiac Function in Ischemic<br />
and Reperfused Mammalian Ventricle, 1324<br />
Effects of 2,4-Dinitrophenol or Low [ATP]i on Cell Excitability<br />
and Action Potential Propagation in Guinea Pig Ventricular<br />
Myocytes, 821<br />
Microvascular Sites and Mechanisms Responsible for Reactive<br />
Hyperemia in the Coronary <strong>Circulation</strong> of the Beating Canine<br />
Heart, 912<br />
ATPase<br />
Product Inhibition of the Ac<strong>to</strong>myosin Subfragment-1 ATPase in<br />
Skeletal, Cardiac, and Smooth Muscle, 1067<br />
Atrial fibrillation<br />
Cholinergically Mediated Tachyarrhythmias Induced by a Single<br />
Extrastimulus in the Isolated Canine Right Atrium, 1254<br />
Mechanism of Flecainide's Antiarrhythmic Action in Experimental<br />
Atrial Fibrillation, 271<br />
Atrial natriuretic fac<strong>to</strong>r<br />
Effect of Inhibition of Endopeptidase 24.11 on Responses <strong>to</strong><br />
Angiotensin II in Human Volunteers, 1501<br />
Expression of A-, B-, and C-Type Natriuretic Peptide Genes in<br />
Failing and Developing Human Ventricles: Correlation With<br />
Expression of the Ca2'-ATPase Gene, 9<br />
Atrial natriuretic peptide secretion<br />
Permeability of Rat Atrial Endocardium, Epicardium, and<br />
Myocardium <strong>to</strong> Large Molecules: Stretch-Dependent Effects,<br />
159<br />
Au<strong>to</strong>nomic nervous system<br />
Sequence of Excitation as a Fac<strong>to</strong>r in Sympathetic-Parasympathetic<br />
Interactions in the Heart, 898<br />
Au<strong>to</strong>radiography<br />
Measurement of Endothelial Permeability <strong>to</strong> 125I-Low Density<br />
Lipoproteins in Rabbit Arteries by Use of En Face Preparations,<br />
883<br />
Au<strong>to</strong>regulation<br />
Impaired Myogenic Responsiveness of Renal Microvessels in<br />
Dahl Salt-Sensitive Rats, 471<br />
B<br />
oB-crystallin<br />
aB-Crystallin in Cardiac Tissue: Association With Actin and<br />
Desmin Filaments, 288<br />
Balloon catheter injury<br />
Regulation of Platelet-Derived Growth Fac<strong>to</strong>r Ligand and<br />
Recep<strong>to</strong>r Gene Expression by a-Thrombin in Vascular<br />
Smooth Muscle Cells, 1285<br />
Balloon injury<br />
Balloon Injury and Interleukin-1 P Induce Nitric Oxide Synthase<br />
Activity in Rat Carotid Arteries, 331<br />
Basilar artery<br />
Effects of External pH on Ionic Currents in Smooth Muscle<br />
Cells From the Basilar Artery of the Guinea Pig, 201<br />
Biochemistry<br />
Myocardial Mechanical, Biochemical, and Structural Alterations<br />
Induced by Chronic Ethanol Ingestion in Rats, 346<br />
Biomechanics<br />
Effects of Fibrous Cap Thickness on Peak Circumferential<br />
Stress in Model Atherosclerotic Vessels, 850<br />
Blood pressure<br />
Effect of Inhibition of Endopeptidase 24.11 on Responses <strong>to</strong><br />
Angiotensin II in Human Volunteers, 1501<br />
Hydrogen Peroxide-Induced Cardiovascular Reflexes: Role of<br />
Hydroxyl Radicals, 295<br />
Blood vessel-parenchyma interdependence<br />
Maturation of Interdependence Between Extra-alveolar Arteries<br />
and Lung Parenchyma in Piglets, 701<br />
Blood vessels<br />
Immunohis<strong>to</strong>chemical and Biochemical Evidence for a Cardiovascular<br />
Mineralocorticoid Recep<strong>to</strong>r, 503<br />
Intraluminal Flow Increases Vascular Tone and 45Ca2' Influx in<br />
the Rabbit Facial Vein, 339
1548 <strong>Circulation</strong> <strong>Research</strong> Vol 71, No 6 December 1992<br />
Body surface mapping<br />
Body Surface Mapping of Ec<strong>to</strong>pic Left Ventricular Activation:<br />
QRS Spectrum in Patients With Prior Myocardial Infarction,<br />
1361<br />
Bradykinin<br />
Potentiation of Endothelium-Dependent Relaxations <strong>to</strong> Bradykinin<br />
by Angiotensin I Converting Enzyme Inhibi<strong>to</strong>rs in<br />
Canine Coronary Artery Involves Both Endothelium-Derived<br />
Relaxing and Hyperpolarizing Fac<strong>to</strong>rs, 137<br />
Brain death<br />
Brain Death-Induced Impairment of Cardiac Contractile Performance<br />
Can Be Reversed by Explantation and May Not<br />
Preclude the Use of Hearts for Transplantation, 1213<br />
Brain natriuretic peptide<br />
Expression of A-, B-, and C-Type Natriuretic Peptide Genes in<br />
Failing and Developing Human Ventricles: Correlation With<br />
Expression of the Ca2+-ATPase Gene, 9<br />
Brain ouabain-like activity<br />
Brain Ouabain-Like Activity and the Sympathoexcita<strong>to</strong>ry and<br />
Pressor Effects of Central Sodium in Rats, 1059<br />
Breakthrough sites<br />
Epicardial Excitation During Ventricular Pacing: Relative Independence<br />
of Breakthrough Sites From Excitation Sequence<br />
in Canine Right Ventricle, 840<br />
C<br />
c-fos mRNA expression<br />
Culture of Renal Arteriolar Smooth Muscle Cells: Mi<strong>to</strong>genic<br />
Responses <strong>to</strong> Angiotensin II, 1143<br />
C-type natriuretic peptide<br />
Expression of A-, B-, and C-Type Natriuretic Peptide Genes in<br />
Failing and Developing Human Ventricles: Correlation With<br />
Expression of the Ca2+-ATPase Gene, 9<br />
Ca2' channels<br />
Effects of External pH on Ionic Currents in Smooth Muscle<br />
Cells From the Basilar Artery of the Guinea Pig, 201<br />
Ionic Currents in Single Smooth Muscle Cells of the Canine<br />
Renal Artery, 745<br />
Ca2+ release<br />
Effect of Perfusate [Ca2+] on Cardiac Sarcoplasmic Reticulum<br />
Ca2' Release Channel in Isolated Rat Hearts, 1049<br />
Ca2' sensitivity<br />
Effects of Cycling and Rigor Crossbridges on the Conformation<br />
of Cardiac Troponin C, 984<br />
Ca2+ transient<br />
Endothelin Reverses the Effects of Acidosis on the Intracellular<br />
Ca2+ Transient and Contractility in Ferret Myocardium, 631<br />
Ca2+ uptake<br />
Effect of Perfusate [Ca2+] on Cardiac Sarcoplasmic Reticulum<br />
Ca2' Release Channel in Isolated Rat Hearts, 1049<br />
Caffeine<br />
Effect of Caffeine on Expression of Cardiac Myosin Heavy<br />
Chain Gene in Adult Hypothyroid and Fetal Rats, 1031<br />
Calci<strong>to</strong>nin gene-related peptide<br />
Endogenous Calci<strong>to</strong>nin Gene-Related Peptide Mediates Nonadrenergic<br />
Noncholinergic Depressor Response <strong>to</strong> Spinal<br />
Cord Stimulation in the Pithed Rat, 357<br />
Calci<strong>to</strong>nin gene-related peptide [8-371<br />
Endogenous Calci<strong>to</strong>nin Gene-Related Peptide Mediates Nonadrenergic<br />
Noncholinergic Depressor Response <strong>to</strong> Spinal<br />
Cord Stimulation in the Pithed Rat, 357<br />
Calcium<br />
Cap<strong>to</strong>pril Enhances Intracellular Calcium Handling and 1-Adrenergic<br />
Responsiveness of Myocardium From Rats With<br />
Postinfarction Failure, 797<br />
Cellular Mechanisms for Synthesis and Secretion of Atrial<br />
Natriuretic Peptide and Brain Natriuretic Peptide in Cultured<br />
Rat Atrial Cells, 1039<br />
Decreased Myofilament Responsiveness in Myocardial Stunning<br />
Follows Transient Calcium Overload During Ischemia and<br />
Reperfusion, 1334<br />
Different Effects of a- and ,B-Adrenergic Stimulation on Cy<strong>to</strong>solic<br />
pH and Myofilament Responsiveness <strong>to</strong> Ca2' in Cardiac<br />
Myocytes, 870<br />
Effect of Ischemia and Reperfusion on Sarcoplasmic Reticulum<br />
Calcium Uptake, 1123<br />
Calcium channel<br />
Effect of Perfusate [Ca211 on Cardiac Sarcoplasmic Reticulum<br />
Ca2' Release Channel in Isolated Rat Hearts, 1049<br />
Calcium channels<br />
Cholesterol Increases the L-Type Voltage-Sensitive Calcium<br />
Channel Current in Arterial Smooth Muscle Cells, 1008<br />
Calcium influx<br />
Intraluminal Flow Increases Vascular Tone and 45Ca21 Influx in<br />
the Rabbit Facial Vein, 339<br />
Calcium overload<br />
ATP Dependence of Calcium Uptake by the Na-Ca Exchanger<br />
of Adult Heart Cells, 210<br />
Myocardial Energetics During Ventricular Fibrillation Investigated<br />
by Magnetization Transfer Nuclear Magnetic Resonance<br />
Spectroscopy, 1111<br />
Calcium release channel<br />
Differences in Cardiac Calcium Release Channel (Ryanodine<br />
Recep<strong>to</strong>r) Expression in Myocardium From Patients With<br />
End-Stage Heart Failure Caused by Ischemic Versus Dilated<br />
Cardiomyopathy, 18<br />
Calcium slow channels<br />
Developmental Changes in Long-Opening Behavior of L-Type<br />
Ca21 Channels in Embryonic Chick Heart Cells, 376<br />
Calcium transients<br />
Mechanisms for the Positive Inotropic Effect of a1-Adrenocep<strong>to</strong>r<br />
Stimulation in Rat Cardiac Myocytes, 673<br />
Calcium uptake<br />
Intraluminal Flow Increases Vascular Tone and 45Ca21 Influx in<br />
the Rabbit Facial Vein, 339<br />
cAMP<br />
Effect of Caffeine on Expression of Cardiac Myosin Heavy<br />
Chain Gene in Adult Hypothyroid and Fetal Rats, 1031<br />
Mechanisms of Vasodilation Induced by NKH477, a Water-<br />
Soluble Forskolin Derivative, in Smooth Muscle of the Porcine<br />
Coronary Artery, 70<br />
Prostaglandin D2 Relaxes Bovine Coronary Arteries by Endothelium-Dependent<br />
Nitric Oxide-Mediated cGMP Formation,<br />
1305<br />
Capillary fluid flux<br />
Blockade of f,3-Integrins in Skin Causes Edema Through Lowering<br />
of Interstitial Fluid Pressure, 978<br />
Cap<strong>to</strong>pril<br />
Cap<strong>to</strong>pril Enhances Intracellular Calcium Handling and 8-Adrenergic<br />
Responsiveness of Myocardium From Rats With<br />
Postinfarction Failure, 797<br />
Ventricular Loading Is Coupled With DNA Synthesis in Adult<br />
Cardiac Myocytes After Acute and Chronic Myocardial Infarction<br />
in Rats, 1379<br />
Carbon dioxide<br />
Res<strong>to</strong>ration of Cerebrovascular CO2 Responsivity by Glutamine<br />
Synthesis Inhibition in Hyperammonemic Rats, 1220<br />
Cardiac actin<br />
Exclusion of Cardiac Myosin Heavy Chain and Actin Gene<br />
Involvement in Hypertrophic Cardiomyopathy of Several<br />
French Families, 3<br />
Cardiac denervation<br />
Time Course of Left Ventricular Function After Cardiac Denervation<br />
in Conscious Dogs, 365<br />
Cardiac development<br />
Multiple Connexins Confer Distinct Regula<strong>to</strong>ry and Conductance<br />
Properties of Gap Junctions in Developing Heart, 1277<br />
Cardiac electrophysiology<br />
Voltage-Dependent Gating and Single-Channel Conductance of<br />
Adult Mammalian Atrial Gap Junctions, 737<br />
Cardiac muscle<br />
Changes in Intracellular Free Calcium Concentration During<br />
Long Exposures <strong>to</strong> Simulated Ischemia in Isolated Mammalian<br />
Ventricular Muscle, 58<br />
Expression of Cystic Fibrosis Transmembrane Regula<strong>to</strong>r Cl-<br />
Channels in Heart, 1002<br />
Product Inhibition of the Ac<strong>to</strong>myosin Subfragment-1 ATPase in<br />
Skeletal, Cardiac, and Smooth Muscle, 1067
Cardiac myocytes<br />
Different Effects of a- and 13-Adrenergic Stimulation on Cy<strong>to</strong>solic<br />
pH and Myofilament Responsiveness <strong>to</strong> Ca2+ in Cardiac<br />
Myocytes, 870<br />
Voltage-Dependent Gating and Single-Channel Conductance of<br />
Adult Mammalian Atrial Gap Junctions, 737<br />
Cardiac myosin heavy chain gene<br />
Effect of Caffeine on Expression of Cardiac Myosin Heavy<br />
Chain Gene in Adult Hypothyroid and Fetal Rats, 1031<br />
Cardiac myosin heavy chains<br />
Exclusion of Cardiac Myosin Heavy Chain and Actin Gene<br />
Involvement in Hypertrophic Cardiomyopathy of Several<br />
French Families, 3<br />
Cardiac output<br />
Indirect Relation Between Rises in Oxygen Consumption and<br />
Left Ventricular Output at Birth in Lambs, 443<br />
Cardiac protection<br />
Adenosine A, Recep<strong>to</strong>r Activation Attenuates Cardiac Injury<br />
Produced by Hydrogen Peroxide, 1101<br />
Cardiac sodium channel<br />
Inward Sodium Current at Resting Potentials in Single Cardiac<br />
Myocytes Induced by the Ischemic Metabolite Lysophosphatidylcholine,<br />
1231<br />
Cardiocyte<br />
Regulation of Na,K-ATPase Gene Expression by Thyroid Hormone<br />
in Rat Cardiocytes, 1457<br />
Cardiocytes<br />
Acidic and Basic Fibroblast Growth Fac<strong>to</strong>rs in Adult Rat Heart<br />
Myocytes: Localization, Regulation in Culture, and Effects on<br />
DNA Synthesis, 251<br />
Cardiomyocytes<br />
a1-Adrenocep<strong>to</strong>r Stimulation Enhances the Delayed Rectifier<br />
K' Current of Guinea Pig Ventricular Cells Through the<br />
Activation of Protein Kinase C, 1441<br />
Cardiomyopathy<br />
Relation Between Ventricular and Myocyte Function With<br />
Tachycardia-Induced Cardiomyopathy, 174<br />
Carvedilol<br />
Effects of Norepinephrine on the Oxidative Pen<strong>to</strong>se Phosphate<br />
Pathway in the Rat Heart, 451<br />
Cat Hydrogen Peroxide-Induced Cardiovascular Reflexes: Role of<br />
Hydroxyl Radicals, 295<br />
Catecholamine<br />
Mechanisms of a1-Adrenergic Vascular Desensitization in Conscious<br />
Dogs, 1185<br />
Catecholamines<br />
Effects of Norepinephrine on the Oxidative Pen<strong>to</strong>se Phosphate<br />
Pathway in the Rat Heart, 451<br />
cDNA expression<br />
Differential Effects of Elevating [K]. on Three Transient Outward<br />
Potassium Channels: Dependence on Channel Inactivation<br />
Mechanisms, 657<br />
Cell coupling<br />
Gap Junctional Conductance in Ventricular Myocyte Pairs<br />
Isolated From Postischemic Rabbit Myocardium, 127<br />
Cell culture<br />
Platelet-Derived Growth Fac<strong>to</strong>r-BB-Induced Suppression of<br />
Smooth Muscle Cell Differentiation, 1518<br />
Cell cultures<br />
Three Types of Naturally Occurring Modified Lipoproteins<br />
Induce Intracellular Lipid Accumulation Due <strong>to</strong> Lipoprotein<br />
Aggregation, 218<br />
Cell injury<br />
Subcellular Electrolyte Alterations During Progressive Hypoxia<br />
and Following Reoxygenation in Isolated Neonatal Rat Ventricular<br />
Myocytes, 106<br />
Cell-cell interaction<br />
Role of Epicardial Mesothelial Cells in the Modification of<br />
Phenotype and Function of Adult Rat Ventricular Myocytes<br />
in Primary Coculture, 40<br />
Subject Index 1549<br />
Cellular Ca2' concentration<br />
Mechanisms of Vasodilation Induced by NKH477, a Water-<br />
Soluble Forskolin Derivative, in Smooth Muscle of the Porcine<br />
Coronary Artery, 70<br />
Cellular electrophysiology<br />
Characterization of the Sodium Current in Single Human Atrial<br />
Myocytes, 535<br />
Central hyper<strong>to</strong>nic saline<br />
Brain Ouabain-like Activity and the Sympathoexcita<strong>to</strong>ry and<br />
Pressor Effects of Central Sodium in Rats, 1059<br />
Cerebral blood flow<br />
Res<strong>to</strong>ration of Cerebrovascular CO2 Responsivity by Glutamine<br />
Synthesis Inhibition in Hyperammonemic Rats, 1220<br />
cGMP<br />
Nitric Oxide Is a Media<strong>to</strong>r of Hypoxic Coronary Vasodilatation:<br />
Relation <strong>to</strong> Adenosine and Cyclooxygenase-Derived Metabolites,<br />
992<br />
Prostaglandin D2 Relaxes Bovine Coronary Arteries by Endothelium-Dependent<br />
Nitric Oxide-Mediated cGMP Formation,<br />
1305<br />
Channels<br />
Multiple Connexins Confer Distinct Regula<strong>to</strong>ry and Conductance<br />
Properties of Gap Junctions in Developing Heart, 1277<br />
Chemotaxis<br />
Kinetics of C5a Release in Cardiac Lymph of Dogs Experiencing<br />
Coronary Artery Ischemia-Reperfusion Injury, 1518<br />
Chicks<br />
Multiple Connexins Confer Distinct Regula<strong>to</strong>ry and Conductance<br />
Properties of Gap Junctions in Developing Heart, 1277<br />
Chloride channel<br />
Cardiac Sarcoplasmic Reticulum Chloride Channels Regulated<br />
by Protein Kinase A, 585<br />
Expression of Cystic Fibrosis Transmembrane Regula<strong>to</strong>r Cl-<br />
Channels in Heart, 1002<br />
Cholesterol<br />
Cholesterol Increases the L-Type Voltage-Sensitive Calcium<br />
Channel Current in Arterial Smooth Muscle Cells, 1008<br />
Cl- transport<br />
Effects of Sero<strong>to</strong>nin on Intracellular pH and Contraction in<br />
Vascular Smooth Muscle, 1294<br />
Cod liver oil<br />
Cod Liver Oil Alters Platelet-Arterial Wall Response <strong>to</strong> Injury<br />
in Pigs, 769<br />
Competitiveness<br />
Ejection Load Changes in Aortic Stenosis: Observations Made<br />
After Balloon Aortic Valvuloplasty, 1174<br />
Complement<br />
Kinetics of C5a Release in Cardiac Lymph of Dogs Experiencing<br />
Coronary Artery Ischemia-Reperfusion Injury, 1518<br />
Complementarity<br />
Ejection Load Changes in Aortic Stenosis: Observations Made<br />
After Balloon Aortic Valvuloplasty, 1174<br />
Conduction system<br />
Au<strong>to</strong>radiographic Characterization of 13-Adrenergic Recep<strong>to</strong>r<br />
Subtype in the Canine Conduction System, 51<br />
Persisting Zones of Slow Impulse Conduction in Developing<br />
Chicken Hearts, 240<br />
Conduction velocity<br />
Persisting Zones of Slow Impulse Conduction in Developing<br />
Chicken Hearts, 240<br />
Connexins<br />
Multiple Connexins Confer Distinct Regula<strong>to</strong>ry and Conductance<br />
Properties of Gap Junctions in Developing Heart, 1277<br />
Connexons<br />
Voltage-Dependent Gating and Single-Channel Conductance of<br />
Adult Mammalian Atrial Gap Junctions, 737<br />
Contractile function<br />
Partial Coronary Stenosis Is Sufficient and Complete Reperfusion<br />
Is Manda<strong>to</strong>ry for Preconditioning the Canine Heart,<br />
1165<br />
Contractile proteins<br />
Mechanisms of Vasodilation Induced by NKH477, a Water-<br />
Soluble Forskolin Derivative, in Smooth Muscle of the Porcine<br />
Coronary Artery, 70
1550 <strong>Circulation</strong> <strong>Research</strong> Vol 71, No 6 December 1992<br />
Contraction<br />
Endothelin Reverses the Effects of Acidosis on the Intracellular<br />
Ca2' Transient and Contractility in Ferret Myocardium, 631<br />
Intraluminal Flow Increases Vascular Tone and 45Ca2' Influx in<br />
the Rabbit Facial Vein, 339<br />
Cooperativity<br />
Inward Sodium Current at Resting Potentials in Single Cardiac<br />
Myocytes Induced by the Ischemic Metabolite Lysophosphatidylcholine,<br />
1231<br />
Coronary artery<br />
Effects on the Rabbit Coronary Artery of LP-805, a New Type<br />
of Releaser of Endothelium-Derived Relaxing Fac<strong>to</strong>r and a<br />
K' Channel Opener, 859<br />
Epicardial Coronary Artery Responses <strong>to</strong> Acetylcholine Are<br />
Impaired in Hypertensive Patients, 776<br />
Gene Transfer In<strong>to</strong> Coronary Arteries of Intact Animals With a<br />
Percutaneous Balloon Catheter, 27<br />
Coronary blood flow<br />
Superoxide Dismutase Enhances Ischemia-Induced Reactive<br />
Hyperemic Flow and Adenosine Release in Dogs: A Role of<br />
5'-Nucleotidase Activity, 558<br />
Coronary circulation<br />
Branching Patterns in the Porcine Coronary Arterial Tree:<br />
Estimation of Flow Heterogeneity, 1200<br />
Coronary Blood Flow After the Regression of Pressure-Overload<br />
Left Ventricular Hypertrophy, 1472<br />
Mechanism of Ergonovine-Induced Hyperconstriction of the<br />
Large Epicardial Coronary Artery in Conscious Dogs a<br />
Month After Arterial Injury, 435<br />
Coronary disease<br />
Effects of Fibrous Cap Thickness on Peak Circumferential<br />
Stress in Model Atherosclerotic Vessels, 850<br />
Coronary microcirculation<br />
Microvascular Sites and Mechanisms Responsible for Reactive<br />
Hyperemia in the Coronary <strong>Circulation</strong> of the Beating Canine<br />
Heart, 912<br />
Coronary occlusion<br />
Biomechanical Properties of Reperfused Transmural Myocardial<br />
Infarcts in Rabbits During the First Week After Infarction:<br />
Implications for Left Ventricular Rupture, 401<br />
Coronary stenosis<br />
Partial Coronary Stenosis Is Sufficient and Complete Reperfusion<br />
Is Manda<strong>to</strong>ry for Preconditioning the Canine Heart,<br />
1165<br />
Coronary vasospasm<br />
Mechanism of Ergonovine-Induced Hyperconstriction of the<br />
Large Epicardial Coronary Artery in Conscious Dogs a<br />
Month After Arterial Injury, 435<br />
Cremaster muscle<br />
Role of Endothelium-Derived Prostaglandins in Hypoxia-Elicited<br />
Arteriolar Dilation in Rat Skeletal Muscle, 790<br />
Cromakalim<br />
Activation of ATP-Sensitive K' Channels by Cromakalim: Effects<br />
on Cellular K' Loss and Cardiac Function in Ischemic<br />
and Reperfused Mammalian Ventricle, 1324<br />
Crossbridge cycling<br />
Endothelin Increases Myofilament Ca21 Sensitivity in a-Toxin-<br />
Permeabilized Rabbit Mesenteric Artery, 951<br />
Crossbridges<br />
Effects of Cycling and Rigor Crossbridges on the Conformation<br />
of Cardiac Troponin C, 984<br />
Cyanide<br />
Verapamil Diminishes Action Potential Changes During Metabolic<br />
Inhibition by Blocking ATP-Regulated Potassium Currents,<br />
87<br />
Cyanotic congenital heart disease<br />
Transcriptional Regulation of Left Ventricular f3-Adrenergic<br />
Recep<strong>to</strong>rs During Chronic Hypoxia, 1465<br />
Cyclic AMP<br />
Expression of Cystic Fibrosis Transmembrane Regula<strong>to</strong>r Cl-<br />
Channels in Heart, 1002<br />
Cyclic flow reductions<br />
Endothelium-Derived Relaxing Fac<strong>to</strong>r Modulates Platelet Aggregation<br />
in an In Vivo Model of Recurrent Platelet Activation,<br />
1447<br />
Cystic fibrosis transmembrane regula<strong>to</strong>r<br />
Expression of Cystic Fibrosis Transmembrane Regula<strong>to</strong>r Cl-<br />
Channels in Heart, 1002<br />
Cy<strong>to</strong>solic free calcium<br />
Lysophosphatidylcholine Inhibits Surface Recep<strong>to</strong>r-Mediated<br />
Intracellular Signals in Endothelial Cells by a Pathway Involving<br />
Protein Kinase C Activation, 1422<br />
Cy<strong>to</strong>solic pH<br />
Different Effects of a- and 13-Adrenergic Stimulation on Cy<strong>to</strong>solic<br />
pH and Myofilament Responsiveness <strong>to</strong> Ca21 in Cardiac<br />
Myocytes, 870<br />
Cy<strong>to</strong>solic [Ca2"]<br />
Relation of Mi<strong>to</strong>chondrial and Cy<strong>to</strong>solic Free Calcium <strong>to</strong><br />
Cardiac Myocyte Recovery After Exposure <strong>to</strong> Anoxia, 605<br />
D<br />
DEAE-dextran<br />
Optimization of Retroviral Vec<strong>to</strong>r-Mediated Gene Transfer<br />
In<strong>to</strong> Endothelial Cells In Vitro, 1508<br />
Delayed excitation<br />
Reflection After Delayed Excitation in a Computer Model of a<br />
Single Fiber, 260<br />
Delayed rectifier K' current<br />
a1-Adrenocep<strong>to</strong>r Stimulation Enhances the Delayed Rectifier<br />
K' Current of Guinea Pig Ventricular Cells Through the<br />
Activation of Protein Kinase C, 1441<br />
Desensitization<br />
Mechanisms of a1-Adrenergic Vascular Desensitization in Conscious<br />
Dogs, 1185<br />
Desmin<br />
aB-Crystallin in Cardiac Tissue: Association With Actin and<br />
Desmin Filaments, 288<br />
Developing hearts<br />
Developmental Changes in Long-Opening Behavior of L-Type<br />
Ca2' Channels in Embryonic Chick Heart Cells, 376<br />
Development<br />
Identification and Characterization of Developmentally Regulated<br />
Genes in Vascular Smooth Muscle Cells, 711<br />
Mouse Phospholamban Gene Expression During Development<br />
In Vivo and In Vitro, 1021<br />
Differentiation<br />
Role of Epicardial Mesothelial Cells in the Modification of<br />
Phenotype and Function of Adult Rat Ventricular Myocytes<br />
in Primary Coculture, 40<br />
DiFrancesco-Noble model<br />
Reflection After Delayed Excitation in a Computer Model of a<br />
Single Fiber, 260<br />
Digi<strong>to</strong>xin<br />
Brain Ouabain-Like Activity and the Sympathoexcita<strong>to</strong>ry and<br />
Pressor Effects of Central Sodium in Rats, 1059<br />
Dihydropyridines<br />
Cholesterol Increases the L-Type Voltage-Sensitive Calcium<br />
Channel Current in Arterial Smooth Muscle Cells, 1008<br />
4,4'-Diisothiocyanostilbene-2,2'-disulfonic acid<br />
Effects of Sero<strong>to</strong>nin on Intracellular pH and Contraction in<br />
Vascular Smooth Muscle, 1294<br />
2,4-Dinitrophenol<br />
Effects of 2,4-Dinitrophenol or Low [ATP]i on Cell Excitability<br />
and Action Potential Propagation in Guinea Pig Ventricular<br />
Myocytes, 821<br />
Dipyridamole<br />
Extracellular and Intracellular Actions of Adenosine and Related<br />
Compounds in the Reperfused Rat Intestine, 720<br />
DNA synthesis<br />
Coronary Collateral Development in Swine After Coronary<br />
Artery Occlusion, 1490<br />
DNA transfection<br />
Decreased Collagen Gene Expression and Absence of Fibrosis<br />
in Thyroid Hormone-Induced Myocardial Hypertrophy: Re-
sponse of Cardiac Fibroblasts <strong>to</strong> Thyroid Hormone In Vitro,<br />
831<br />
Dogs<br />
Mechanisms of ai-Adrenergic Vascular Desensitization in Conscious<br />
Dogs, 1185<br />
Drug interaction<br />
Inward Sodium Current at Resting Potentials in Single Cardiac<br />
Myocytes Induced by the Ischemic Metabolite Lysophosphatidylcholine,<br />
1231<br />
Dual coronary perfusion<br />
Reperfusion-Induced Arrhythmias: A Role for Washout of<br />
Extracellular Pro<strong>to</strong>ns? 1429<br />
E<br />
EC 2.7.4.6<br />
Membrane-Bound Nucleoside Diphosphate Kinase Activity in<br />
Atrial Cells of Frog, Guinea Pig, and Human, 808<br />
Ec<strong>to</strong>pic ventricular beats<br />
Epicardial Excitation During Ventricular Pacing: Relative Independence<br />
of Breakthrough Sites From Excitation Sequence<br />
in Canine Right Ventricle, 840<br />
Edema<br />
Blockade of 81-Integrins in Skin Causes Edema Through Lowering<br />
of Interstitial Fluid Pressure, 978<br />
Edi<strong>to</strong>rial<br />
Cellular and Molecular Biology of the Cardiovascular System, 1<br />
Effective arterial elastance<br />
Mechanical Matching of the Left Ventricle With the Arterial<br />
System in Exercising Dogs, 481<br />
Eicosapentaenoic Acid<br />
Cod Liver Oil Alters Platelet-Arterial Wall Response <strong>to</strong> Injury<br />
in Pigs, 769<br />
Electrocardiography<br />
Mechanism of Flecainide's Antiarrhythmic Action in Experimental<br />
Atrial Fibrillation, 271<br />
Elements<br />
Subcellular Electrolyte Alterations During Progressive Hypoxia<br />
and Following Reoxygenation in Isolated Neonatal Rat Ventricular<br />
Myocytes, 106<br />
Embryo<br />
Influence of Vascular Smooth Muscle Heterogeneity on Angiotensin<br />
Converting Enzyme Activity in Chicken Embryonic<br />
Aorta and in Endothelial Cells in Culture, 923<br />
Embryoid bodies<br />
Mouse Phospholamban Gene Expression During Development<br />
In Vivo and In Vitro, 1021<br />
Embryonic chicken hearts<br />
Persisting Zones of Slow Impulse Conduction in Developing<br />
Chicken Hearts, 240<br />
Embryonic heart cells<br />
Developmental Changes in Long-Opening Behavior of L-Type<br />
Ca2' Channels in Embryonic Chick Heart Cells, 376<br />
End-sys<strong>to</strong>lic elastance<br />
Mechanical Matching of the Left Ventricle With the Arterial<br />
System in Exercising Dogs, 481<br />
Endocardial potential<br />
A Model Study of Volume Conduc<strong>to</strong>r Effects on Endocardial<br />
and Intracavitary Potentials, 511<br />
Endocardium<br />
Permeability of Rat Atrial Endocardium, Epicardium, and<br />
Myocardium <strong>to</strong> Large Molecules: Stretch-Dependent Effects,<br />
159<br />
Endocrine<br />
Decreased Collagen Gene Expression and Absence of Fibrosis<br />
in Thyroid Hormone-Induced Myocardial Hypertrophy: Response<br />
of Cardiac Fibroblasts <strong>to</strong> Thyroid Hormone In Vitro,<br />
831<br />
Endocy<strong>to</strong>sis<br />
Permeability of Rat Atrial Endocardium, Epicardium, and<br />
Myocardium <strong>to</strong> Large Molecules: Stretch-Dependent Effects,<br />
159<br />
Endopeptidase 24.11<br />
Effect of Inhibition of Endopeptidase 24.11 on Responses <strong>to</strong><br />
Angiotensin II in Human Volunteers, 1501<br />
Subject Index 1551<br />
Endothelial adhesivity<br />
Thrombin Recep<strong>to</strong>r 14-Amino Acid Peptide Mediates Endothelial<br />
Hyperadhesivity and Neutrophil Adhesion by P-Selectin-Dependent<br />
Mechanism, 1015<br />
Endothelial cell<br />
Comprehensive Model of Transport and Metabolism of Adenosine<br />
and S-Adenosylhomocysteine in the Guinea Pig Heart,<br />
590<br />
Coronary Collateral Development in Swine After Coronary<br />
Artery Occlusion, 1490<br />
Effects of Hypoxia on Heparan Sulfate in Bovine Aortic and<br />
Pulmonary Artery Endothelial Cells, 782<br />
Interaction Between Microvascular al- and a2-Adrenocep<strong>to</strong>rs<br />
and Endothelium-Derived Relaxing Fac<strong>to</strong>r, 188<br />
Lysophosphatidylcholine Inhibits Surface Recep<strong>to</strong>r-Mediated<br />
Intracellular Signals in Endothelial Cells by a Pathway Involving<br />
Protein Kinase C Activation, 1422<br />
Optimization of Retroviral Vec<strong>to</strong>r-Mediated Gene Transfer<br />
In<strong>to</strong> Endothelial Cells In Vitro, 1508<br />
Endothelial permeability<br />
Albumin Transport Characteristics of Rat Aorta in Early Phase<br />
of Hypertension, 932<br />
Endothelin<br />
Cellular Mechanisms for Synthesis and Secretion of Atrial<br />
Natriuretic Peptide and Brain Natriuretic Peptide in Cultured<br />
Rat Atrial Cells, 1039<br />
Endothelin Increases Myofilament Ca21 Sensitivity in a-Toxin-<br />
Permeabilized Rabbit Mesenteric Artery, 951<br />
Isolated Pulmonary Resistance Vessels From Fetal Lambs:<br />
Contractile Behavior and Responses <strong>to</strong> Indomethacin and<br />
Endothelin-1, 320<br />
Suppression of Endothelin-1 Secretion by Lysophosphatidylcholine<br />
in Oxidized Low Density Lipoprotein in Cultured Vascular<br />
Endothelial Cells, 614<br />
Endothelin-1<br />
Endothelin-1 Enhances Calcium Entry Through T-Type Calcium<br />
Channels in Cultured Neonatal Rat Ventricular Myocytes,<br />
1242<br />
Endothelin Reverses the Effects of Acidosis on the Intracellular<br />
Ca2' Transient and Contractility in Ferret Myocardium, 631<br />
Endothelium<br />
Endothelial Modulation of the Ouabain-Induced Contraction in<br />
Human Placental Vessels, 943<br />
Epicardial Coronary Artery Responses <strong>to</strong> Acetylcholine Are<br />
Impaired in Hypertensive Patients, 776<br />
Influence of Vascular Smooth Muscle Heterogeneity on Angiotensin<br />
Converting Enzyme Activity in Chicken Embryonic<br />
Aorta and in Endothelial Cells in Culture, 923<br />
Measurement of Endothelial Permeability <strong>to</strong> "2I-Low Density<br />
Lipoproteins in Rabbit Arteries by Use of En Face Preparations,<br />
883<br />
Mechanism of Ergonovine-Induced Hyperconstriction of the<br />
Large Epicardial Coronary Artery in Conscious Dogs a<br />
Month After Arterial Injury, 435<br />
Permeability of Rat Atrial Endocardium, Epicardium, and<br />
Myocardium <strong>to</strong> Large Molecules: Stretch-Dependent Effects,<br />
159<br />
Role of Endothelium-Derived Prostaglandins in Hypoxia-Elicited<br />
Arteriolar Dilation in Rat Skeletal Muscle, 790<br />
Role of Neutrophil Adherence Recep<strong>to</strong>rs (CD 18) in Lung<br />
Permeability Following Lower Torso Ischemia, 82<br />
Endothelium-derived hyperpolarizing fac<strong>to</strong>r<br />
Effects on the Rabbit Coronary Artery of LP-805, a New Type<br />
of Releaser of Endothelium-Derived Relaxing Fac<strong>to</strong>r and a<br />
K' Channel Opener, 859<br />
Potentiation of Endothelium-Dependent Relaxations <strong>to</strong> Bradykinin<br />
by Angiotensin I Converting Enzyme Inhibi<strong>to</strong>rs in<br />
Canine Coronary Artery Involves Both Endothelium-Derived<br />
Relaxing and Hyperpolarizing Fac<strong>to</strong>rs, 137<br />
Endothelium-derived relaxing fac<strong>to</strong>r<br />
Effects on the Rabbit Coronary Artery of LP-805, a New Type<br />
of Releaser of Endothelium-Derived Relaxing Fac<strong>to</strong>r and a<br />
K+ Channel Opener, 859
1552 <strong>Circulation</strong> <strong>Research</strong> Vol 71, No 6 December 1992<br />
Endothelium-Derived Relaxing Fac<strong>to</strong>r Modulates Platelet Aggregation<br />
in an In Vivo Model of Recurrent Platelet Activation,<br />
1447<br />
Interaction Between Microvascular al- and a2-Adrenocep<strong>to</strong>rs<br />
and Endothelium-Derived Relaxing Fac<strong>to</strong>r, 188<br />
Lysophosphatidylcholine Inhibits Bradykinin-Induced Phosphoinositide<br />
Hydrolysis and Calcium Transients in Cultured<br />
Bovine Aortic Endothelial Cells, 1410<br />
Energetics<br />
Comprehensive Model of Transport and Metabolism of Adenosine<br />
and S-Adenosylhomocysteine in the Guinea Pig Heart,<br />
590<br />
Energy metabolism<br />
Adenosine A, Recep<strong>to</strong>r Activation Attenuates Cardiac Injury<br />
Produced by Hydrogen Peroxide, 1101<br />
Myocardial Energetics During Ventricular Fibrillation Investigated<br />
by Magnetization Transfer Nuclear Magnetic Resonance<br />
Spectroscopy, 1111<br />
Epicardial isochrons<br />
Epicardial Excitation During Ventricular Pacing: Relative Independence<br />
of Breakthrough Sites From Excitation Sequence<br />
in Canine Right Ventricle, 840<br />
Epicardial myocytes<br />
Age-Related Appearance of Outward Currents May Contribute<br />
<strong>to</strong> Developmental Differences in Ventricular Repolarization,<br />
1390<br />
Epicardial potential mapping<br />
Epicardial Excitation During Ventricular Pacing: Relative Independence<br />
of Breakthrough Sites From Excitation Sequence<br />
in Canine Right Ventricle, 840<br />
Epicardium<br />
Permeability of Rat Atrial Endocardium, Epicardium, and<br />
Myocardium <strong>to</strong> Large Molecules: Stretch-Dependent Effects,<br />
159<br />
Ergonovine<br />
Mechanism of Ergonovine-Induced Hyperconstriction of the<br />
Large Epicardial Coronary Artery in Conscious Dogs a<br />
Month After Arterial Injury, 435<br />
Ethanol<br />
Myocardial Mechanical, Biochemical, and Structural Alterations<br />
Induced by Chronic Ethanol Ingestion in Rats, 346<br />
5-(N-Ethyl-N-isopropyl)amiloride<br />
Effects of Sero<strong>to</strong>nin on Intracellular pH and Contraction in<br />
Vascular Smooth Muscle, 1294<br />
Euglycemia<br />
Correlation Between [5 -3H]Glucose and [U-'4CJDeoxyglucose<br />
as Markers of Glycolysis in Reperfused Myocardium, 689<br />
Excitability<br />
Effects of 2,4-Dinitrophenol or Low [ATP]i on Cell Excitability<br />
and Action Potential Propagation in Guinea Pig Ventricular<br />
Myocytes, 821<br />
Excitation-contraction coupling<br />
Functional Expression of an Inactivating Potassium Channel<br />
Cloned From Human Heart, 732<br />
Exclusion<br />
Exclusion of Cardiac Myosin Heavy Chain and Actin Gene<br />
Involvement in Hypertrophic Cardiomyopathy of Several<br />
French Families, 3<br />
Extracellular matrix<br />
Decreased Collagen Gene Expression and Absence of Fibrosis<br />
in Thyroid Hormone-Induced Myocardial Hypertrophy: Response<br />
of Cardiac Fibroblasts <strong>to</strong> Thyroid Hormone In Vitro,<br />
831<br />
Rat Carotid Neointimal Smooth Muscle Cells Reexpress a<br />
Developmentally Regulated mRNA Phenotype During Repair<br />
of Arterial Injury, 759<br />
Extracellular matrix degradation<br />
Cultured Rat Aortic Vascular Smooth Muscle Cells Digest<br />
Naturally Produced Extracellular Matrix: Involvement of<br />
Plasminogen-Dependent and Plasminogen-Independent<br />
Pathways, 385<br />
Extracellular pH<br />
Changes in Extracellular and Intracellular pH in Ischemic<br />
Rabbit Papillary Muscle, 460<br />
Extracellular potassium<br />
Reperfusion Arrhythmias in Isolated Perfused Pig Hearts: Inhomogeneities<br />
in Extracellular Potassium, ST and TQ Potentials,<br />
and Transmembrane Action Potentials, 1131<br />
Extracellular potassium accumulation<br />
Differential Effects of Elevating [K]. on Three Transient Outward<br />
Potassium Channels: Dependence on Channel Inactivation<br />
Mechanisms, 657<br />
Extracellular potassium concentration<br />
Sympathetic Stimulation and Norepinephrine Infusion Modulate<br />
Extracellular Potassium Concentration During Acute<br />
Myocardial Ischemia, 1078<br />
F<br />
Familial hypertrophic cardiomyopathy<br />
Exclusion of Cardiac Myosin Heavy Chain and Actin Gene<br />
Involvement in Hypertrophic Cardiomyopathy of Several<br />
French Families, 3<br />
Fatty acids<br />
Dissociation Between Contractile Function and Oxidative Metabolism<br />
in Postischemic Myocardium: Attenuation by Ruthenium<br />
Red Administered During Reperfusion, 567<br />
Fetal bovine serum<br />
Platelet-Derived Growth Fac<strong>to</strong>r-BB-Induced Suppression of<br />
Smooth Muscle Cell Differentiation, 1525<br />
Fetal heart<br />
Expression of A-, B-, and C-Type Natriuretic Peptide Genes in<br />
Failing and Developing Human Ventricles: Correlation With<br />
Expression of the Ca2+-ATPase Gene, 9<br />
Fetus<br />
Indirect Relation Between Rises in Oxygen Consumption and<br />
Left Ventricular Output at Birth in Lambs, 443<br />
Isolated Pulmonary Resistance Vessels From Fetal Lambs:<br />
Contractile Behavior and Responses <strong>to</strong> Indomethacin and<br />
Endothelin-1, 320<br />
Fibroblast growth fac<strong>to</strong>r recep<strong>to</strong>rs<br />
Acidic and Basic Fibroblast Growth Fac<strong>to</strong>rs in Adult Rat Heart<br />
Myocytes: Localization, Regulation in Culture, and Effects on<br />
DNA Synthesis, 251<br />
Fibronectin<br />
Age-Related Changes in Fibronectin Expression in Spontaneously<br />
Hypertensive, Wistar-Kyo<strong>to</strong>, and Wistar Rat Hearts,<br />
1341<br />
Finite element models<br />
Arterial Mechanics in Spontaneously Hypertensive Rats: Mechanical<br />
Properties, Hydraulic Conductivity, and Two-Phase<br />
(Solid/Fluid) Finite Element Models, 145<br />
Flecainide<br />
Mechanism of Flecainide's Antiarrhythmic Action in Experimental<br />
Atrial Fibrillation, 271<br />
Floating objective<br />
Microvascular Sites and Mechanisms Responsible for Reactive<br />
Hyperemia in the Coronary <strong>Circulation</strong> of the Beating Canine<br />
Heart, 912<br />
Flow<br />
Intraluminal Flow Increases Vascular Tone and 45Ca2' Influx in<br />
the Rabbit Facial Vein, 339<br />
Flow cy<strong>to</strong>metry<br />
Ventricular Loading Is Coupled With DNA Synthesis in Adult<br />
Cardiac Myocytes After Acute and Chronic Myocardial Infarction<br />
in Rats, 1379<br />
Flow heterogeneity<br />
Branching Patterns in the Porcine Coronary Arterial Tree:<br />
Estimation of Flow Heterogeneity, 1200<br />
Fluorescence videomicroscopy<br />
Relation Between Vasa Recta Blood Flow and Renal Interstitial<br />
Hydrostatic Pressure During Pressure Natriuresis, 1153<br />
Forskolin derivative<br />
Mechanisms of Vasodilation Induced by NKH477, a Water-<br />
Soluble Forskolin Derivative, in Smooth Muscle of the Porcine<br />
Coronary Artery, 70<br />
Fractals<br />
Branching Patterns in the Porcine Coronary Arterial Tree:<br />
Estimation of Flow Heterogeneity, 1200
Free radical<br />
Hydrogen Peroxide-Induced Cardiovascular Reflexes: Role of<br />
Hydroxyl Radicals, 295<br />
FUT-175<br />
Effects of Complement Activation in the Isolated Heart: Role of<br />
the Terminal Complement Components, 303<br />
G<br />
G proteins<br />
Membrane-Bound Nucleoside Diphosphate Kinase Activity in<br />
Atrial Cells of Frog, Guinea Pig, and Human, 808<br />
Gap junctions<br />
Effects of 2,4-Dinitrophenol or Low [ATP]i on Cell Excitability<br />
and Action Potential Propagation in Guinea Pig Ventricular<br />
Myocytes, 821<br />
Gap Junctional Channels in Adult Mammalian Sinus Nodal<br />
Cells: Immunolocalization and Electrophysiology, 229<br />
Gap Junctional Conductance in Ventricular Myocyte Pairs<br />
Isolated From Postischemic Rabbit Myocardium, 127<br />
Multiple Connexins Confer Distinct Regula<strong>to</strong>ry and Conductance<br />
Properties of Gap Junctions in Developing Heart, 1277<br />
Voltage-Dependent Gating and Single-Channel Conductance of<br />
Adult Mammalian Atrial Gap Junctions, 737<br />
Gating modification<br />
Inward Sodium Current at Resting Potentials in Single Cardiac<br />
Myocytes Induced by the Ischemic Metabolite Lysophosphatidylcholine,<br />
1231<br />
Gene expression<br />
Decreased Collagen Gene Expression and Absence of Fibrosis<br />
in Thyroid Hormone-Induced Myocardial Hypertrophy: Response<br />
of Cardiac Fibroblasts <strong>to</strong> Thyroid Hormone In Vitro,<br />
831<br />
Identification and Characterization of Developmentally Regulated<br />
Genes in Vascular Smooth Muscle Cells, 711<br />
Pro<strong>to</strong>-oncogene Expression in Porcine Myocardium Subjected<br />
<strong>to</strong> Ischemia and Reperfusion, 1351<br />
Gene transfer<br />
Gene Transfer In<strong>to</strong> Coronary Arteries of Intact Animals With a<br />
Percutaneous Balloon Catheter, 27<br />
Optimization of Retroviral Vec<strong>to</strong>r-Mediated Gene Transfer<br />
In<strong>to</strong> Endothelial Cells In Vitro, 1508<br />
Gizzard<br />
Product Inhibition of the Ac<strong>to</strong>myosin Subfragment-1 ATPase in<br />
Skeletal, Cardiac, and Smooth Muscle, 1067<br />
Glibenclamide-sensitive K' channel<br />
Effects on the Rabbit Coronary Artery of LP-805, a New Type<br />
of Releaser of Endothelium-Derived Relaxing Fac<strong>to</strong>r and a<br />
K' Channel Opener, 859<br />
Glucose<br />
Dissociation Between Contractile Function and Oxidative Metabolism<br />
in Postischemic Myocardium: Attenuation by Ruthenium<br />
Red Administered During Reperfusion, 567<br />
Glucose-6-phosphate dehydrogenase<br />
Effects of Norepinephrine on the Oxidative Pen<strong>to</strong>se Phosphate<br />
Pathway in the Rat Heart, 451<br />
Glutamine<br />
Res<strong>to</strong>ration of Cerebrovascular CO2 Responsivity by Glutamine<br />
Synthesis Inhibition in Hyperammonemic Rats, 1220<br />
Glycogen<br />
Correlation Between [5-3H]Glucose and [U-_4C]Deoxyglucose<br />
as Markers of Glycolysis in Reperfused Myocardium, 689<br />
Glycolysis<br />
Correlation Between [5-3H]Glucose and [U-14C]Deoxyglucose<br />
as Markers of Glycolysis in Reperfused Myocardium, 689<br />
GTP regula<strong>to</strong>ry proteins<br />
Positive Chronotropic Responses Induced by a1-Adrenergic<br />
Stimulation of Normal and "Ischemic" Purkinje Fibers Have<br />
Different Recep<strong>to</strong>r-Effec<strong>to</strong>r Coupling Mechanisms, 526<br />
H<br />
H-7 a1-Adrenocep<strong>to</strong>r Stimulation Enhances the Delayed Rectifier<br />
K' Current of Guinea Pig Ventricular Cells Through the<br />
Activation of Protein Kinase C, 1441<br />
Subject Index 1553<br />
HCO3--Cl- exchange<br />
HCO3--Dependent Intracellular pH Regulation in the Premature<br />
Myocardium, 1314<br />
HCO3- transport<br />
Effects of Sero<strong>to</strong>nin on Intracellular pH and Contraction in<br />
Vascular Smooth Muscle, 1294<br />
Heart<br />
Adenosine A, Recep<strong>to</strong>r Activation Attenuates Cardiac Injury<br />
Produced by Hydrogen Peroxide, 1101<br />
Au<strong>to</strong>radiographic Characterization of p-Adrenergic Recep<strong>to</strong>r<br />
Subtype in the Canine Conduction System, 51<br />
aB-Crystallin in Cardiac Tissue: Association With Actin and<br />
Desmin Filaments, 288<br />
Changes in Intracellular Free Calcium Concentration During<br />
Long Exposures <strong>to</strong> Simulated Ischemia in Isolated Mammalian<br />
Ventricular Muscle, 58<br />
Characterization of Angiotensin II Recep<strong>to</strong>r Subtypes in Rat<br />
Heart, 1482<br />
Immunohis<strong>to</strong>chemical and Biochemical Evidence for a Cardiovascular<br />
Mineralocorticoid Recep<strong>to</strong>r, 503<br />
Mechanisms for the Positive Inotropic Effect of a1-Adrenocep<strong>to</strong>r<br />
Stimulation in Rat Cardiac Myocytes, 673<br />
Mouse Phospholamban Gene Expression During Development<br />
In Vivo and In Vitro, 1021<br />
Nitric Oxide Synthase in Cardiac Nerve Fibers and Neurons of<br />
Rat and Guinea Pig Heart, 1526<br />
Heart-derived fibroblast growth fac<strong>to</strong>rs<br />
Acidic and Basic Fibroblast Growth Fac<strong>to</strong>rs in Adult Rat Heart<br />
Myocytes: Localization, Regulation in Culture, and Effects on<br />
DNA Synthesis, 251<br />
Heart failure<br />
Cap<strong>to</strong>pril Enhances Intracellular Calcium Handling and B-Adrenergic<br />
Responsiveness of Myocardium From Rats With<br />
Postinfarction Failure, 797<br />
Expression of A-, B-, and C-Type Natriuretic Peptide Genes in<br />
Failing and Developing Human Ventricles: Correlation With<br />
Expression of the Ca2'-ATPase Gene, 9<br />
Heart rate<br />
Basal Metabolism Adds a Significant Offset <strong>to</strong> Unloaded Myocardial<br />
Oxygen Consumption per Minute, 414<br />
Mechanism of Flecainide's Antiarrhythmic Action in Experimental<br />
Atrial Fibrillation, 271<br />
Sequence of Excitation as a Fac<strong>to</strong>r in Sympathetic-Parasympathetic<br />
Interactions in the Heart, 898<br />
Heart transplantation<br />
Brain Death-Induced Impairment of Cardiac Contractile Performance<br />
Can Be Reversed by Explantation and May Not<br />
Preclude the Use of Hearts for Transplantation, 1213<br />
Heparan sulfate<br />
Effects of Hypoxia on Heparan Sulfate in Bovine Aortic and<br />
Pulmonary Artery Endothelial Cells, 782<br />
Heparin<br />
Heparin Adheres <strong>to</strong> the Damaged Arterial Wall and Inhibits Its<br />
Thrombogenicity, 577<br />
Hibernating myocardium<br />
Mechanisms of Subendocardial Dysfunction in Response <strong>to</strong><br />
Exercise in Dogs With Severe Left Ventricular Hypertrophy,<br />
423<br />
H202<br />
Adenosine A, Recep<strong>to</strong>r Activation Attenuates Cardiac Injury<br />
Produced by Hydrogen Peroxide, 1101<br />
Homocysteine<br />
Comprehensive Model of Transport and Metabolism of Adenosine<br />
and S-Adenosylhomocysteine in the Guinea Pig Heart,<br />
590<br />
Human atrium<br />
Characterization of the Sodium Current in Single Human Atrial<br />
Myocytes, 535<br />
Human Ca2+-ATPase<br />
Expression of A-, B-, and C-Type Natriuretic Peptide Genes in<br />
Failing and Developing Human Ventricles: Correlation With<br />
Expression of the Ca2+-ATPase Gene, 9
1554 <strong>Circulation</strong> <strong>Research</strong> Vol 71, No 6 December 1992<br />
Human myofibrillar proteins<br />
Accumulation and Assembly of Myosin in Hypertrophic Cardiomyopathy<br />
With the 403 Arg <strong>to</strong> Gln f3-Myosin Heavy Chain<br />
Mutation, 1404<br />
Human placental vessels<br />
Endothelial Modulation of the Ouabain-Induced Contraction in<br />
Human Placental Vessels, 943<br />
Human umbilical vein endothelial cells<br />
Thrombin Recep<strong>to</strong>r 14-Amino Acid Peptide Mediates Endothelial<br />
Hyperadhesivity and Neutrophil Adhesion by P-Selectin-Dependent<br />
Mechanism, 1015<br />
Hydraulic conductivity<br />
Arterial Mechanics in Spontaneously Hypertensive Rats: Mechanical<br />
Properties, Hydraulic Conductivity, and Two-Phase<br />
(Solid/Fluid) Finite Element Models, 145<br />
Hydrogen peroxide<br />
Depression of Cardiac Sarcolemmal Phospholipase D Activity<br />
by Oxidant-Induced Thiol Modification, 970<br />
Hydroxyl radical<br />
Quantification of Hydroxyl Radical and Its Lack of Relevance <strong>to</strong><br />
Myocardial Injury During Early Reperfusion After Graded<br />
Ischemia in Rat Hearts, 96<br />
Hyperglycemia<br />
Correlation Between [5-3HJGlucose and [U-14C]Deoxyglucose<br />
as Markers of Glycolysis in Reperfused Myocardium, 689<br />
Hyperinsulinemia<br />
Physiological Hyperinsulinemia Inhibits Myocardial Protein<br />
Degradation In Vivo in the Canine Heart, 393<br />
Hyperplasia<br />
Culture of Renal Arteriolar Smooth Muscle Cells: Mi<strong>to</strong>genic<br />
Responses <strong>to</strong> Angiotensin II, 1143<br />
Hypertension<br />
Albumin Transport Characteristics of Rat Aorta in Early Phase<br />
of Hypertension, 932<br />
Culture of Renal Arteriolar Smooth Muscle Cells: Mi<strong>to</strong>genic<br />
Responses <strong>to</strong> Angiotensin II, 1143<br />
Epicardial Coronary Artery Responses <strong>to</strong> Acetylcholine Are<br />
Impaired in Hypertensive Patients, 776<br />
Hypertrophy<br />
Culture of Renal Arteriolar Smooth Muscle Cells: Mi<strong>to</strong>genic<br />
Responses <strong>to</strong> Angiotensin II, 1143<br />
Decreased Collagen Gene Expression and Absence of Fibrosis<br />
in Thyroid Hormone-Induced Myocardial Hypertrophy: Response<br />
of Cardiac Fibroblasts <strong>to</strong> Thyroid Hormone In Vitro,<br />
831<br />
Endothelin-1 Enhances Calcium Entry Through T-Type Calcium<br />
Channels in Cultured Neonatal Rat Ventricular Myocytes,<br />
1242<br />
Hypochlorous acid<br />
Depression of Cardiac Sarcolemmal Phospholipase D Activity<br />
by Oxidant-Induced Thiol Modification, 970<br />
Hypoxia<br />
Dependence of Hypoxic Cellular Calcium Loading on Na+-Ca2+<br />
Exchange, 547<br />
Nitric Oxide Is a Media<strong>to</strong>r of Hypoxic Coronary Vasodilatation:<br />
Relation <strong>to</strong> Adenosine and Cyclooxygenase-Derived Metabolites,<br />
992<br />
Role of Endothelium-Derived Prostaglandins in Hypoxia-Elicited<br />
Arteriolar Dilation in Rat Skeletal Muscle, 790<br />
Subcellular Electrolyte Alterations During Progressive Hypoxia<br />
and Following Reoxygenation in Isolated Neonatal Rat Ventricular<br />
Myocytes, 106<br />
Transcriptional Regulation of Left Ventricular fl-Adrenergic<br />
Recep<strong>to</strong>rs During Chronic Hypoxia, 1465<br />
Hypoxic coronary vasodilatation<br />
Nitric Oxide Is a Media<strong>to</strong>r of Hypoxic Coronary Vasodilatation:<br />
Relation <strong>to</strong> Adenosine and Cyclooxygenase-Derived Metabolites,<br />
992<br />
IAANS<br />
Effects of Cycling and Rigor Crossbridges on the Conformation<br />
of Cardiac Troponin C, 984<br />
Idiopathic dilated cardiomyopathy<br />
Differences in Cardiac Calcium Release Channel (Ryanodine<br />
Recep<strong>to</strong>r) Expression in Myocardium From Patients With<br />
End-Stage Heart Failure Caused by Ischemic Versus Dilated<br />
Cardiomyopathy, 18<br />
Immunofluorescence<br />
Accumulation and Assembly of Myosin in Hypertrophic Cardiomyopathy<br />
With the 403 Arg <strong>to</strong> Gln /3-Myosin Heavy Chain<br />
Mutation, 1404<br />
Inactivation<br />
Inward Sodium Current at Resting Potentials in Single Cardiac<br />
Myocytes Induced by the Ischemic Metabolite Lysophosphatidylcholine,<br />
1231<br />
Indo-1<br />
Different Effects of a- and ,B-Adrenergic Stimulation on Cy<strong>to</strong>solic<br />
pH and Myofilament Responsiveness <strong>to</strong> Ca21 in Cardiac<br />
Myocytes, 870<br />
Relation of Mi<strong>to</strong>chondrial and Cy<strong>to</strong>solic Free Calcium <strong>to</strong><br />
Cardiac Myocyte Recovery After Exposure <strong>to</strong> Anoxia, 605<br />
Infarct healing<br />
Biomechanical Properties of Reperfused Transmural Myocardial<br />
Infarcts in Rabbits During the First Week After Infarction:<br />
Implications for Left Ventricular Rupture, 401<br />
Inflamma<strong>to</strong>ry media<strong>to</strong>rs<br />
Leukotriene B4 Mediates Shear Rate-Dependent Leukocyte<br />
Adhesion in Mesenteric Venules, 906<br />
Innervation<br />
Nitric Oxide Synthase in Cardiac Nerve Fibers and Neurons of<br />
Rat and Guinea Pig Heart, 1526<br />
Inosi<strong>to</strong>l 1,4,5-trisphosphate<br />
Lysophosphatidylcholine Inhibits Surface Recep<strong>to</strong>r-Mediated<br />
Intracellular Signals in Endothelial Cells by a Pathway Involving<br />
Protein Kinase C Activation, 1422<br />
Insulin-like growth fac<strong>to</strong>r<br />
Platelet-Derived Growth Fac<strong>to</strong>r Isoforms Decrease Insulin-like<br />
Growth Fac<strong>to</strong>r I Gene Expression in Rat Vascular Smooth<br />
Muscle Cells and Selectively Stimulate the Biosynthesis of<br />
Insulin-like Growth Fac<strong>to</strong>r Binding Protein 4, 646<br />
Insulin-like growth fac<strong>to</strong>r binding protein<br />
Platelet-Derived Growth Fac<strong>to</strong>r Isoforms Decrease Insulin-like<br />
Growth Fac<strong>to</strong>r I Gene Expression in Rat Vascular Smooth<br />
Muscle Cells and Selectively Stimulate the Biosynthesis of<br />
Insulin-like Growth Fac<strong>to</strong>r Binding Protein 4, 646<br />
f3-Integrins<br />
Blockade of 81-Integrins in Skin Causes Edema Through Lowering<br />
of Interstitial Fluid Pressure, 978<br />
Interferon gamma<br />
Interferon-y and Tumor Necrosis Fac<strong>to</strong>r Synergize <strong>to</strong> Induce<br />
Nitric Oxide Production and Inhibit Mi<strong>to</strong>chondrial Respiration<br />
in Vascular Smooth Muscle Cells, 1268<br />
Interleukin-1,8<br />
Balloon Injury and Interleukin-1 f8 Induce Nitric Oxide Synthase<br />
Activity in Rat Carotid Arteries, 331<br />
Platelet-Derived Growth Fac<strong>to</strong>r Suppresses and Fibroblast<br />
Growth Fac<strong>to</strong>r Enhances Cy<strong>to</strong>kine-Induced Production of<br />
Nitric Oxide by Cultured Smooth Muscle Cells: Effects on<br />
Cell Proliferation, 1088<br />
Interlobular artery<br />
Impaired Myogenic Responsiveness of Renal Microvessels in<br />
Dahl Salt-Sensitive Rats, 471<br />
Interstitial fluid pressure<br />
Blockade of 831-Integrins in Skin Causes Edema Through Lowering<br />
of Interstitial Fluid Pressure, 978<br />
Intestinal ischemia<br />
Leukotriene B4 Mediates Shear Rate-Dependent Leukocyte<br />
Adhesion in Mesenteric Venules, 906<br />
Intracavitary potential<br />
A Model Study of Volume Conduc<strong>to</strong>r Effects on Endocardial<br />
and Intracavitary Potentials, 511<br />
Intracellular calcium concentration<br />
Lysophosphatidylcholine Inhibits Bradykinin-Induced Phosphoinositide<br />
Hydrolysis and Calcium Transients in Cultured<br />
Bovine Aortic Endothelial Cells, 1410
Intracellular free calcium concentration<br />
Changes in Intracellular Free Calcium Concentration During<br />
Long Exposures <strong>to</strong> Simulated Ischemia in Isolated Mammalian<br />
Ventricular Muscle, 58<br />
Intracellular pH<br />
Changes in Extracellular and Intracellular pH in Ischemic<br />
Rabbit Papillary Muscle, 460<br />
HCO3--Dependent Intracellular pH Regulation in the Premature<br />
Myocardium, 1314<br />
Ionic currents<br />
Ionic Currents in Single Smooth Muscle Cells of the Canine<br />
Renal Artery, 745<br />
Ischemia<br />
ATP Dependence of Calcium Uptake by the Na-Ca Exchanger<br />
of Adult Heart Cells, 210<br />
aB-Crystallin in Cardiac Tissue: Association With Actin and<br />
Desmin Filaments, 288<br />
Brain Death-Induced Impairment of Cardiac Contractile Performance<br />
Can Be Reversed by Explantation and May Not<br />
Preclude the Use of Hearts for Transplantation, 1213<br />
Changes in Intracellular Free Calcium Concentration During<br />
Long Exposures <strong>to</strong> Simulated Ischemia in Isolated Mammalian<br />
Ventricular Muscle, 58<br />
Decreased Myofilament Responsiveness in Myocardial Stunning<br />
Follows Transient Calcium Overload During Ischemia and<br />
Reperfusion, 1334<br />
Dependence of Hypoxic Cellular Calcium Loading on Na+-Ca2+<br />
Exchange, 547<br />
Effect of Ischemia and Reperfusion on Sarcoplasmic Reticulum<br />
Calcium Uptake, 1123<br />
Extracellular and Intracellular Actions of Adenosine and Related<br />
Compounds in the Reperfused Rat Intestine, 720<br />
Hydrogen Peroxide-Induced Cardiovascular Reflexes: Role of<br />
Hydroxyl Radicals, 295<br />
Pro<strong>to</strong>-oncogene Expression in Porcine Myocardium Subjected<br />
<strong>to</strong> Ischemia and Reperfusion, 1351<br />
Quantification of Hydroxyl Radical and Its Lack of Relevance <strong>to</strong><br />
Myocardial Injury During Early Reperfusion After Graded<br />
Ischemia in Rat Hearts, 96<br />
Superoxide Dismutase Enhances Ischemia-Induced Reactive<br />
Hyperemic Flow and Adenosine Release in Dogs: A Role of<br />
5'-Nucleotidase Activity, 558<br />
Verapamil Diminishes Action Potential Changes During Metabolic<br />
Inhibition by Blocking ATP-Regulated Potassium Currents,<br />
87<br />
Ischemic arrhythmias<br />
Positive Chronotropic Responses Induced by a1-Adrenergic<br />
Stimulation of Normal and "Ischemic" Purkinje Fibers Have<br />
Different Recep<strong>to</strong>r-Effec<strong>to</strong>r Coupling Mechanisms, 526<br />
Ischemic cardiomyopathy<br />
Differences in Cardiac Calcium Release Channel (Ryanodine<br />
Recep<strong>to</strong>r) Expression in Myocardium From Patients With<br />
End-Stage Heart Failure Caused by Ischemic Versus Dilated<br />
Cardiomyopathy, 18<br />
Isolated canine hearts<br />
Basal Metabolism Adds a Significant Offset <strong>to</strong> Unloaded Myocardial<br />
Oxygen Consumption per Minute, 414<br />
Isolated guinea pig heart<br />
Nitric Oxide Is a Media<strong>to</strong>r of Hypoxic Coronary Vasodilatation:<br />
Relation <strong>to</strong> Adenosine and Cyclooxygenase-Derived Metabolites,<br />
992<br />
Isolated hearts<br />
Effect of Ischemia and Reperfusion on Sarcoplasmic Reticulum<br />
Calcium Uptake, 1123<br />
K<br />
K' channels<br />
Effects of External pH on Ionic Currents in Smooth Muscle<br />
Cells From the Basilar Artery of the Guinea Pig, 201<br />
Functional Expression of an Inactivating Potassium Channel<br />
Cloned From Human Heart, 732<br />
Ionic Currents in Single Smooth Muscle Cells of the Canine<br />
Renal Artery, 745<br />
Subject Index 1555<br />
K' channel openers<br />
Activation of ATP-Sensitive K' Channels by Cromakalim: Effects<br />
on Cellular K' Loss and Cardiac Function in Ischemic<br />
and Reperfused Mammalian Ventricle, 1324<br />
Effects on the Rabbit Coronary Artery of LP-805, a New Type<br />
of Releaser of Endothelium-Derived Relaxing Fac<strong>to</strong>r and a<br />
K' Channel Opener, 859<br />
Kinetics<br />
Comprehensive Model of Transport and Metabolism of Adenosine<br />
and S-Adenosylhomocysteine in the Guinea Pig Heart,<br />
590<br />
Kinin recep<strong>to</strong>rs<br />
Potentiation of Endothelium-Dependent Relaxations <strong>to</strong> Bradykinin<br />
by Angiotensin I Converting Enzyme Inhibi<strong>to</strong>rs in<br />
Canine Coronary Artery Involves Both Endothelium-Derived<br />
Relaxing and Hyperpolarizing Fac<strong>to</strong>rs, 137<br />
Kininase II<br />
Potentiation of Endothelium-Dependent Relaxations <strong>to</strong> Bradykinin<br />
by Angiotensin I Converting Enzyme Inhibi<strong>to</strong>rs in<br />
Canine Coronary Artery Involves Both Endothelium-Derived<br />
Relaxing and Hyperpolarizing Fac<strong>to</strong>rs, 137<br />
L<br />
L-type Ca2' channels<br />
Developmental Changes in Long-Opening Behavior of L-Type<br />
Ca2' Channels in Embryonic Chick Heart Cells, 376<br />
Large deformation<br />
Arterial Mechanics in Spontaneously Hypertensive Rats: Mechanical<br />
Properties, Hydraulic Conductivity, and Two-Phase<br />
(Solid/Fluid) Finite Element Models, 145<br />
Left anterior descending coronary artery<br />
Effect of Brief Myocardial Ischemia on Sympathetic Coronary<br />
Vasoconstriction, 960<br />
Left circumflex coronary artery<br />
Effect of Brief Myocardial Ischemia on Sympathetic Coronary<br />
Vasoconstriction, 960<br />
Left ventricular afterload<br />
Time Course of Left Ventricular Function After Cardiac Denervation<br />
in Conscious Dogs, 365<br />
Left ventricular function<br />
Time Course of Left Ventricular Function After Cardiac Denervation<br />
in Conscious Dogs, 365<br />
Left ventricular hypertrophy<br />
Mechanisms of Subendocardial Dysfunction in Response <strong>to</strong><br />
Exercise in Dogs With Severe Left Ventricular Hypertrophy,<br />
423<br />
Left ventricular loading in aortic stenosis<br />
Ejection Load Changes in Aortic Stenosis: Observations Made<br />
After Balloon Aortic Valvuloplasty, 1174<br />
Left ventricular myocardium<br />
Expression of A-, B-, and C-Type Natriuretic Peptide Genes in<br />
Failing and Developing Human Ventricles: Correlation With<br />
Expression of the Ca2'-ATPase Gene, 9<br />
Left ventricular sys<strong>to</strong>lic dynamics<br />
Ejection Load Changes in Aortic Stenosis: Observations Made<br />
After Balloon Aortic Valvuloplasty, 1174<br />
Linkage analysis<br />
Exclusion of Cardiac Myosin Heavy Chain and Actin Gene<br />
Involvement in Hypertrophic Cardiomyopathy of Several<br />
French Families, 3<br />
Lipid accumulation<br />
Three Types of Naturally Occurring Modified Lipoproteins<br />
Induce Intracellular Lipid Accumulation Due <strong>to</strong> Lipoprotein<br />
Aggregation, 218<br />
Lipid aggregation<br />
Three Types of Naturally Occurring Modified Lipoproteins<br />
Induce Intracellular Lipid Accumulation Due <strong>to</strong> Lipoprotein<br />
Aggregation, 218<br />
Lipoprotein<br />
Suppression of Endothelin-1 Secretion by Lysophosphatidylcholine<br />
in Oxidized Low Density Lipoprotein in Cultured Vascular<br />
Endothelial Cells, 614
1556 <strong>Circulation</strong> <strong>Research</strong> Vol 71, No 6 December 1992<br />
Lipoprotein aggregation<br />
Three Types of Naturally Occurring Modified Lipoproteins<br />
Induce Intracellular Lipid Accumulation Due <strong>to</strong> Lipoprotein<br />
Aggregation, 218<br />
Losartan<br />
Characterization of Angiotensin II Recep<strong>to</strong>r Subtypes in Rat<br />
Heart, 1482<br />
Low density lipoproteins<br />
Measurement of Endothelial Permeability <strong>to</strong> 1251 -Low Density<br />
Lipoproteins in Rabbit Arteries by Use of En Face Preparations,<br />
883<br />
Luciferase<br />
Gene Transfer In<strong>to</strong> Coronary Arteries of Intact Animals With a<br />
Percutaneous Balloon Catheter, 27<br />
Luciferase gene<br />
Regulation of Na,K-ATPase Gene Expression by Thyroid Hormone<br />
in Rat Cardiocytes, 1457<br />
Lung growth<br />
Maturation of Interdependence Between Extra-alveolar Arteries<br />
and Lung Parenchyma in Piglets, 701<br />
Lung micromechanics<br />
Maturation of Interdependence Between Extra-alveolar Arteries<br />
and Lung Parenchyma in Piglets, 701<br />
Lysophosphatidylcholine<br />
Lysophosphatidylcholine Inhibits Bradykinin-Induced Phosphoinositide<br />
Hydrolysis and Calcium Transients in Cultured<br />
Bovine Aortic Endothelial Cells, 1410<br />
Lysophosphatidylcholine Inhibits Surface Recep<strong>to</strong>r-Mediated<br />
Intracellular Signals in Endothelial Cells by a Pathway Involving<br />
Protein Kinase C Activation, 1422<br />
M<br />
Magnetization transfer<br />
Myocardial Energetics During Ventricular Fibrillation Investigated<br />
by Magnetization Transfer Nuclear Magnetic Resonance<br />
Spectroscopy, 1111<br />
Membrane attack complex<br />
Effects of Complement Activation in the Isolated Heart: Role of<br />
the Terminal Complement Components, 303<br />
Membrane depolarization<br />
Impaired Myogenic Responsiveness of Renal Microvessels in<br />
Dahl Salt-Sensitive Rats, 471<br />
Metabolism<br />
Dissociation Between Contractile Function and Oxidative Metabolism<br />
in Postischemic Myocardium: Attenuation by Ruthenium<br />
Red Administered During Reperfusion, 567<br />
Methionine sulfoximine<br />
Res<strong>to</strong>ration of Cerebrovascular CO2 Responsivity by Glutamine<br />
Synthesis Inhibition in Hyperammonemic Rats, 1220<br />
Microcirculation<br />
Effect of Hypertension and Hypertrophy on Coronary Microvascular<br />
Pressure, 120<br />
Extracellular and Intracellular Actions of Adenosine and Related<br />
Compounds in the Reperfused Rat Intestine, 720<br />
Interaction Between Microvascular al- and a2-Adrenocep<strong>to</strong>rs<br />
and Endothelium-Derived Relaxing Fac<strong>to</strong>r, 188<br />
Microsatellites<br />
Exclusion of Cardiac Myosin Heavy Chain and Actin Gene<br />
Involvement in Hypertrophic Cardiomyopathy of Several<br />
French Families, 3<br />
Microvascular endothelium<br />
Leukotriene B4 Mediates Shear Rate-Dependent Leukocyte<br />
Adhesion in Mesenteric Venules, 906<br />
Microvascular pressure<br />
Effect of Hypertension and Hypertrophy on Coronary Microvascular<br />
Pressure, 120<br />
Mi<strong>to</strong>chondria<br />
Interferon-y and Tumor Necrosis Fac<strong>to</strong>r Synergize <strong>to</strong> Induce<br />
Nitric Oxide Production and Inhibit Mi<strong>to</strong>chondrial Respiration<br />
in Vascular Smooth Muscle Cells, 1268<br />
Mi<strong>to</strong>chondrial [Ca2l]<br />
Relation of Mi<strong>to</strong>chondrial and Cy<strong>to</strong>solic Free Calcium <strong>to</strong><br />
Cardiac Myocyte Recovery After Exposure <strong>to</strong> Anoxia, 605<br />
Mi<strong>to</strong>tic division<br />
Ventricular Loading Is Coupled With DNA Synthesis in Adult<br />
Cardiac Myocytes After Acute and Chronic Myocardial Infarction<br />
in Rats, 1379<br />
Mode-2 behavior<br />
Developmental Changes in Long-Opening Behavior of L-Type<br />
Ca2' Channels in Embryonic Chick Heart Cells, 376<br />
Moderate ischemia<br />
Partial Coronary Stenosis Is Sufficient and Complete Reperfusion<br />
Is Manda<strong>to</strong>ry for Preconditioning the Canine Heart,<br />
1165<br />
Modified lipoproteins<br />
Three Types of Naturally Occurring Modified Lipoproteins<br />
Induce Intracellular Lipid Accumulation Due <strong>to</strong> Lipoprotein<br />
Aggregation, 218<br />
Molecular biology<br />
Effects of Norepinephrine on the Oxidative Pen<strong>to</strong>se Phosphate<br />
Pathway in the Rat Heart, 451<br />
Molecular cloning<br />
Differential Effects of Elevating [K], on Three Transient Outward<br />
Potassium Channels: Dependence on Channel Inactivation<br />
Mechanisms, 657<br />
Monoclonal antibodies<br />
Immunohis<strong>to</strong>chemical and Biochemical Evidence for a Cardiovascular<br />
Mineralocorticoid Recep<strong>to</strong>r, 503<br />
NG-Monomethyl L-arginine<br />
Interaction Between Microvascular al- and a2-Adrenocep<strong>to</strong>rs<br />
and Endothelium-Derived Relaxing Fac<strong>to</strong>r, 188<br />
Mouse<br />
Mouse Phospholamban Gene Expression During Development<br />
In Vivo and In Vitro, 1021<br />
mRNA<br />
Cellular Mechanisms for Synthesis and Secretion of Atrial<br />
Natriuretic Peptide and Brain Natriuretic Peptide in Cultured<br />
Rat Atrial Cells, 1039<br />
Differences in Cardiac Calcium Release Channel (Ryanodine<br />
Recep<strong>to</strong>r) Expression in Myocardium From Patients With<br />
End-Stage Heart Failure Caused by Ischemic Versus Dilated<br />
Cardiomyopathy, 18<br />
Transcriptional Regulation of Left Ventricular ,B-Adrenergic<br />
Recep<strong>to</strong>rs During Chronic Hypoxia, 1465<br />
Multiple wavelet hypothesis<br />
Cholinergically Mediated Tachyarrhythmias Induced by a Single<br />
Extrastimulus in the Isolated Canine Right Atrium, 1254<br />
Muscarinic K' channels<br />
Membrane-Bound Nucleoside Diphosphate Kinase Activity in<br />
Atrial Cells of Frog, Guinea Pig, and Human, 808<br />
Muscle<br />
Effects of Cycling and Rigor Crossbridges on the Conformation<br />
of Cardiac Troponin C, 984<br />
Muscle regeneration<br />
Role of Epicardial Mesothelial Cells in the Modification of<br />
Phenotype and Function of Adult Rat Ventricular Myocytes<br />
in Primary Coculture, 40<br />
Myelin basic protein/microtubule-associated protein 2 kinase<br />
Angiotensin II Stimulates Two Myelin Basic Protein/Microtubule-Associated<br />
Protein 2 Kinases in Cultured Vascular<br />
Smooth Muscle Cells, 620<br />
Myocardial blood flow<br />
Mechanisms of Subendocardial Dysfunction in Response <strong>to</strong><br />
Exercise in Dogs With Severe Left Ventricular Hypertrophy,<br />
423<br />
Myocardial contractility<br />
Adenosine A, Recep<strong>to</strong>r Activation Attenuates Cardiac Injury<br />
Produced by Hydrogen Peroxide, 1101<br />
Myocardial contraction<br />
Different Effects of a- and 3-Adrenergic Stimulation on Cy<strong>to</strong>solic<br />
pH and Myofilament Responsiveness <strong>to</strong> Ca2' in Cardiac<br />
Myocytes, 870<br />
Myocardial energetics<br />
Effect of Reduced Aortic Compliance on Cardiac Efficiency and<br />
Contractile Function of In Situ Canine Left Ventricle, 490
Myocardial infarction<br />
Body Surface Mapping of Ec<strong>to</strong>pic Left Ventricular Activation:<br />
QRS Spectrum in Patients With Prior Myocardial Infarction,<br />
1361<br />
Cap<strong>to</strong>pril Enhances Intracellular Calcium Handling and P-Adrenergic<br />
Responsiveness of Myocardium From Rats With<br />
Postinfarction Failure, 797<br />
Effects of Complement Activation in the Isolated Heart: Role of<br />
the Terminal Complement Components, 303<br />
Effects of Fibrous Cap Thickness on Peak Circumferential<br />
Stress in Model Atherosclerotic Vessels, 850<br />
Kinetics of C5a Release in Cardiac Lymph of Dogs Experiencing<br />
Coronary Artery Ischemia-Reperfusion Injury, 1518<br />
Myocardial ischemia<br />
Activation of ATP-Sensitive K' Channels by Cromakalim: Effects<br />
on Cellular K' Loss and Cardiac Function in Ischemic<br />
and Reperfused Mammalian Ventricle, 1324<br />
Changes in Extracellular and Intracellular pH in Ischemic<br />
Rabbit Papillary Muscle, 460<br />
Correlation Between [5-3H]Glucose and [U-J4C]Deoxyglucose<br />
as Markers of Glycolysis in Reperfused Myocardium, 689<br />
Effect of Brief Myocardial Ischemia on Sympathetic Coronary<br />
Vasoconstriction, 960<br />
Effects of Complement Activation in the Isolated Heart: Role of<br />
the Terminal Complement Components, 303<br />
Sympathetic Stimulation and Norepinephrine Infusion Modulate<br />
Extracellular Potassium Concentration During Acute<br />
Myocardial Ischemia, 1078<br />
Myocardial protection<br />
Brain Death-Induced Impairment of Cardiac Contractile Performance<br />
Can Be Reversed by Explantation and May Not<br />
Preclude the Use of Hearts for Transplantation, 1213<br />
Myocardial rupture<br />
Biomechanical Properties of Reperfused Transmural Myocardial<br />
Infarcts in Rabbits During the First Week After Infarction:<br />
Implications for Left Ventricular Rupture, 401<br />
Myocardial stunning<br />
Effect of Brief Myocardial Ischemia on Sympathetic Coronary<br />
Vasoconstriction, 960<br />
Myocardial tearing<br />
Biomechanical Properties of Reperfused Transmural Myocardial<br />
Infarcts in Rabbits During the First Week After Infarction:<br />
Implications for Left Ventricular Rupture, 401<br />
Myocardium<br />
Age-Related Changes in Fibronectin Expression in Spontaneously<br />
Hypertensive, Wistar-Kyo<strong>to</strong>, and Wistar Rat Hearts,<br />
1341<br />
Comprehensive Model of Transport and Metabolism of Adenosine<br />
and S-Adenosylhomocysteine in the Guinea Pig Heart,<br />
590<br />
Decreased Collagen Gene Expression and Absence of Fibrosis<br />
in Thyroid Hormone-Induced Myocardial Hypertrophy: Response<br />
of Cardiac Fibroblasts <strong>to</strong> Thyroid Hormone In Vitro,<br />
831<br />
Superoxide Dismutase Enhances Ischemia-Induced Reactive<br />
Hyperemic Flow and Adenosine Release in Dogs: A Role of<br />
5-Nucleotidase Activity, 558<br />
Myocyte function<br />
Relation Between Ventricular and Myocyte Function With<br />
Tachycardia-Induced Cardiomyopathy, 174<br />
Myocyte loss<br />
Myocardial Mechanical, Biochemical, and Structural Alterations<br />
Induced by Chronic Ethanol Ingestion in Rats, 346<br />
Myocytes<br />
Relation of Mi<strong>to</strong>chondrial and Cy<strong>to</strong>solic Free Calcium <strong>to</strong><br />
Cardiac Myocyte Recovery After Exposure <strong>to</strong> Anoxia, 605<br />
Myofibrillar integrity<br />
Accumulation and Assembly of Myosin in Hypertrophic Cardiomyopathy<br />
With the 403 Arg <strong>to</strong> Gln B-Myosin Heavy Chain<br />
Mutation, 1404<br />
Myofilament Ca2' sensitivity<br />
Endothelin Increases Myofilament Ca2+ Sensitivity in a-Toxin-<br />
Permeabilized Rabbit Mesenteric Artery, 951<br />
Subject Index 1557<br />
Myosin heavy chain<br />
Platelet-Derived Growth Fac<strong>to</strong>r-BB-Induced Suppression of<br />
Smooth Muscle Cell Differentiation, 1518<br />
Myosin heavy chain isoforms<br />
Persisting Zones of Slow Impulse Conduction in Developing<br />
Chicken Hearts, 240<br />
Myosin light chain phosphorylation<br />
Endothelin Increases Myofilament Ca21 Sensitivity in a-Toxin-<br />
Permeabilized Rabbit Mesenteric Artery, 951<br />
N<br />
Na-Ca exchange<br />
ATP Dependence of Calcium Uptake by the Na-Ca Exchanger<br />
of Adult Heart Cells, 210<br />
Na+-Ca2+ exchange<br />
Dependence of Hypoxic Cellular Calcium Loading on Na+-Ca2'<br />
Exchange, 547<br />
Na+-H+ exchange<br />
Endothelin Reverses the Effects of Acidosis on the Intracellular<br />
Ca2' Transient and Contractility in Ferret Myocardium, 631<br />
HCO3--Dependent Intracellular pH Regulation in the Premature<br />
Myocardium, 1314<br />
Na+ transport<br />
Effects of Sero<strong>to</strong>nin on Intracellular pH and Contraction in<br />
Vascular Smooth Muscle, 1294<br />
Na,K-ATPase<br />
Brain Ouabain-Like Activity and the Sympathoexcita<strong>to</strong>ry and<br />
Pressor Effects of Central Sodium in Rats, 1059<br />
Regulation of Na,K-ATPase Gene Expression by Thyroid Hormone<br />
in Rat Cardiocytes, 1457<br />
Natriuresis<br />
Effect of Inhibition of Endopeptidase 24.11 on Responses <strong>to</strong><br />
Angiotensin II in Human Volunteers, 1501<br />
Natriuretic peptide<br />
Phenotype-Related Alteration in Expression of Natriuretic Peptide<br />
Recep<strong>to</strong>rs in Aortic Smooth Muscle Cells, 34<br />
Natriuretic peptide recep<strong>to</strong>rs<br />
Phenotype-Related Alteration in Expression of Natriuretic Peptide<br />
Recep<strong>to</strong>rs in Aortic Smooth Muscle Cells, 34<br />
Neonatal<br />
Age-Related Appearance of Outward Currents May Contribute<br />
<strong>to</strong> Developmental Differences in Ventricular Repolarization,<br />
1390<br />
Neuronal norepinephrine reuptake<br />
Mechanism of Hind Limb Vasoconstriction Due <strong>to</strong> Cyclosporin<br />
A in the Dog, 1159<br />
Neuropeptide Y<br />
Sequence of Excitation as a Fac<strong>to</strong>r in Sympathetic-Parasympathetic<br />
Interactions in the Heart, 898<br />
Neutropenia<br />
Role of Neutrophil Adherence Recep<strong>to</strong>rs (CD 18) in Lung<br />
Permeability Following Lower Torso Ischemia, 82<br />
Neutrophil<br />
Extracellular and Intracellular Actions of Adenosine and Related<br />
Compounds in the Reperfused Rat Intestine, 720<br />
Kinetics of CSa Release in Cardiac Lymph of Dogs Experiencing<br />
Coronary Artery Ischemia-Reperfusion Injury, 1518<br />
Thrombin Recep<strong>to</strong>r 14-Amino Acid Peptide Mediates Endothelial<br />
Hyperadhesivity and Neutrophil Adhesion by P-Selectin-Dependent<br />
Mechanism, 1015<br />
Neutrophil sequestration<br />
Role of Neutrophil Adherence Recep<strong>to</strong>rs (CD 18) in Lung<br />
Permeability Following Lower Torso Ischemia, 82<br />
Newborn<br />
Indirect Relation Between Rises in Oxygen Consumption and<br />
Left Ventricular Output at Birth in Lambs, 443<br />
Newborn myocytes<br />
HCO3--Dependent Intracellular pH Regulation in the Premature<br />
Myocardium, 1314<br />
Nitric oxide<br />
Balloon Injury and Interleukin-1 18 Induce Nitric Oxide Synthase<br />
Activity in Rat Carotid Arteries, 331
1558 <strong>Circulation</strong> <strong>Research</strong> Vol 71, No 6 December 1992<br />
Interferon-y and Tumor Necrosis Fac<strong>to</strong>r Synergize <strong>to</strong> Induce<br />
Nitric Oxide Production and Inhibit Mi<strong>to</strong>chondrial Respiration<br />
in Vascular Smooth Muscle Cells, 1268<br />
Nitric Oxide Is a Media<strong>to</strong>r of Hypoxic Coronary Vasodilatation:<br />
Relation <strong>to</strong> Adenosine and Cyclooxygenase-Derived Metabolites,<br />
992<br />
Nitric Oxide Synthase in Cardiac Nerve Fibers and Neurons of<br />
Rat and Guinea Pig Heart, 1526<br />
Platelet-Derived Growth Fac<strong>to</strong>r Suppresses and Fibroblast<br />
Growth Fac<strong>to</strong>r Enhances Cy<strong>to</strong>kine-Induced Production of<br />
Nitric Oxide by Cultured Smooth Muscle Cells: Effects on<br />
Cell Proliferation, 1088<br />
Potentiation of Endothelium-Dependent Relaxations <strong>to</strong> Bradykinin<br />
by Angiotensin I Converting Enzyme Inhibi<strong>to</strong>rs in<br />
Canine Coronary Artery Involves Both Endothelium-Derived<br />
Relaxing and Hyperpolarizing Fac<strong>to</strong>rs, 137<br />
Prostaglandin D2 Relaxes Bovine Coronary Arteries by Endothelium-Dependent<br />
Nitric Oxide-Mediated cGMP Formation,<br />
1305<br />
NG-Nitro-L-arginine<br />
Potentiation of Endothelium-Dependent Relaxations <strong>to</strong> Bradykinin<br />
by Angiotensin I Converting Enzyme Inhibi<strong>to</strong>rs in<br />
Canine Coronary Artery Involves Both Endothelium-Derived<br />
Relaxing and Hyperpolarizing Fac<strong>to</strong>rs, 137<br />
Nonadrenergic noncholinergic depressor response<br />
Endogenous Calci<strong>to</strong>nin Gene-Related Peptide Mediates Nonadrenergic<br />
Noncholinergic Depressor Response <strong>to</strong> Spinal<br />
Cord Stimulation in the Pithed Rat, 357<br />
Norepinephrine<br />
Sequence of Excitation as a Fac<strong>to</strong>r in Sympathetic-Parasympathetic<br />
Interactions in the Heart, 898<br />
Sympathetic Stimulation and Norepinephrine Infusion Modulate<br />
Extracellular Potassium Concentration During Acute<br />
Myocardial Ischemia, 1078<br />
Nuclear fibroblast growth fac<strong>to</strong>rs<br />
Acidic and Basic Fibroblast Growth Fac<strong>to</strong>rs in Adult Rat Heart<br />
Myocytes: Localization, Regulation in Culture, and Effects on<br />
DNA Synthesis, 251<br />
Nuclear hyperplasia<br />
Ventricular Loading Is Coupled With DNA Synthesis in Adult<br />
Cardiac Myocytes After Acute and Chronic Myocardial Infarction<br />
in Rats, 1379<br />
Nuclear pro<strong>to</strong>-oncogenes<br />
Pro<strong>to</strong>-oncogene Expression in Porcine Myocardium Subjected<br />
<strong>to</strong> Ischemia and Reperfusion, 1351<br />
Nucleoside diphosphate kinase<br />
Membrane-Bound Nucleoside Diphosphate Kinase Activity in<br />
Atrial Cells of Frog, Guinea Pig, and Human, 808<br />
0<br />
Osmolarity<br />
Res<strong>to</strong>ration of Cerebrovascular CO2 Responsivity by Glutamine<br />
Synthesis Inhibition in Hyperammonemic Rats, 1220<br />
Ouabain<br />
Endothelial Modulation of the Ouabain-Induced Contraction in<br />
Human Placental Vessels, 943<br />
Brain Ouabain-Like Activity and the Sympathoexcita<strong>to</strong>ry and<br />
Pressor Effects of Central Sodium in Rats, 1059<br />
Outflow tract<br />
Persisting Zones of Slow Impulse Conduction in Developing<br />
Chicken Hearts, 240<br />
Oxidative stress<br />
Adenosine A, Recep<strong>to</strong>r Activation Attenuates Cardiac Injury<br />
Produced by Hydrogen Peroxide, 1101<br />
Oxygen<br />
Isolated Pulmonary Resistance Vessels From Fetal Lambs:<br />
Contractile Behavior and Responses <strong>to</strong> Indomethacin and<br />
Endothelin-1, 320<br />
Role of Endothelium-Derived Prostaglandins in Hypoxia-Elicited<br />
Arteriolar Dilation in Rat Skeletal Muscle, 790<br />
Oxygen consumption<br />
Indirect Relation Between Rises in Oxygen Consumption and<br />
Left Ventricular Output at Birth in Lambs, 443<br />
Oxygen-derived free radicals<br />
Superoxide Dismutase Enhances Ischemia-Induced Reactive<br />
Hyperemic Flow and Adenosine Release in Dogs: A Role of<br />
5-Nucleotidase Activity, 558<br />
p<br />
P-selectin<br />
Thrombin Recep<strong>to</strong>r 14-Amino Acid Peptide Mediates Endothelial<br />
Hyperadhesivity and Neutrophil Adhesion by P-Selectin-Dependent<br />
Mechanism, 1015<br />
Pace mapping<br />
Body Surface Mapping of Ec<strong>to</strong>pic Left Ventricular Activation:<br />
QRS Spectrum in Patients With Prior Myocardial Infarction,<br />
1361<br />
Papillary muscle<br />
Myocardial Mechanical, Biochemical, and Structural Alterations<br />
Induced by Chronic Ethanol Ingestion in Rats, 346<br />
Paracellular pathway<br />
Permeability of Rat Atrial Endocardium, Epicardium, and<br />
Myocardium <strong>to</strong> Large Molecules: Stretch-Dependent Effects,<br />
159<br />
Patch clamp<br />
a1-Adrenocep<strong>to</strong>r Stimulation Enhances the Delayed Rectifier<br />
K' Current of Guinea Pig Ventricular Cells Through the<br />
Activation of Protein Kinase C, 1441<br />
Activation of ATP-Sensitive K' Channels by Cromakalim: Effects<br />
on Cellular K' Loss and Cardiac Function in Ischemic<br />
and Reperfused Mammalian Ventricle, 1324<br />
Developmental Changes in Long-Opening Behavior of L-Type<br />
Ca21 Channels in Embryonic Chick Heart Cells, 376<br />
Verapamil Diminishes Action Potential Changes During Metabolic<br />
Inhibition by Blocking ATP-Regulated Potassium Currents,<br />
87<br />
Patch-clamp single-channel conductance<br />
Inward Sodium Current at Resting Potentials in Single Cardiac<br />
Myocytes Induced by the Ischemic Metabolite Lysophosphatidylcholine,<br />
1231<br />
PD123177<br />
Characterization of Angiotensin II Recep<strong>to</strong>r Subtypes in Rat<br />
Heart, 1482<br />
Percutaneous transluminal coronary angioplasty<br />
In Vitro Effects of a Recombinant Toxin Targeted <strong>to</strong> the<br />
Fibroblast Growth Fac<strong>to</strong>r Recep<strong>to</strong>r on Rat Vascular Smooth<br />
Muscle and Endothelial Cells, 640<br />
Peripheral vasoconstriction<br />
Mechanism of Hind Limb Vasoconstriction Due <strong>to</strong> Cyclosporin<br />
A in the Dog, 1159<br />
Permeability<br />
Measurement of Endothelial Permeability <strong>to</strong> 1251-Low Density<br />
Lipoproteins in Rabbit Arteries by Use of En Face Preparations,<br />
883<br />
pH<br />
Effects of External pH on Ionic Currents in Smooth Muscle<br />
Cells From the Basilar Artery of the Guinea Pig, 201<br />
Phenotypic modulation<br />
Phenotype-Related Alteration in Expression of Natriuretic Peptide<br />
Recep<strong>to</strong>rs in Aortic Smooth Muscle Cells, 34<br />
Phenylephrine<br />
a1-Adrenocep<strong>to</strong>r Stimulation Enhances the Delayed Rectifier<br />
K' Current of Guinea Pig Ventricular Cells Through the<br />
Activation of Protein Kinase C, 1441<br />
Phorbol ester<br />
Endothelin-1 Enhances Calcium Entry Through T-Type Calcium<br />
Channels in Cultured Neonatal Rat Ventricular Myocytes,<br />
1242<br />
6-Phosphogluconate dehydrogenase<br />
Effects of Norepinephrine on the Oxidative Pen<strong>to</strong>se Phosphate<br />
Pathway in the Rat Heart, 451<br />
Phosphoinositide hydrolysis<br />
Lysophosphatidylcholine Inhibits Bradykinin-Induced Phosphoinositide<br />
Hydrolysis and Calcium Transients in Cultured<br />
Bovine Aortic Endothelial Cells, 1410
Phospholamban<br />
Mouse Phospholamban Gene Expression During Development<br />
In Vivo and In Vitro, 1021<br />
Phospholipase D<br />
Depression of Cardiac Sarcolemmal Phospholipase D Activity<br />
by Oxidant-Induced Thiol Modification, 970<br />
Phosphorus nuclear magnetic resonance<br />
Myocardial Energetics During Ventricular Fibrillation Investigated<br />
by Magnetization Transfer Nuclear Magnetic Resonance<br />
Spectroscopy, 1111<br />
Phosphorylation<br />
Cardiac Sarcoplasmic Reticulum Chloride Channels Regulated<br />
by Protein Kinase A, 585<br />
Pig Heart<br />
Pro<strong>to</strong>-oncogene Expression in Porcine Myocardium Subjected<br />
<strong>to</strong> Ischemia and Reperfusion, 1351<br />
Nitric Oxide Is a Media<strong>to</strong>r of Hypoxic Coronary Vasodilatation:<br />
Relation <strong>to</strong> Adenosine and Cyclooxygenase-Derived Metabolites,<br />
992<br />
Pithed rat<br />
Endogenous Calci<strong>to</strong>nin Gene-Related Peptide Mediates Nonadrenergic<br />
Noncholinergic Depressor Response <strong>to</strong> Spinal<br />
Cord Stimulation in the Pithed Rat, 357<br />
Plasminogen<br />
Cultured Rat Aortic Vascular Smooth Muscle Cells Digest<br />
Naturally Produced Extracellular Matrix: Involvement of<br />
Plasminogen-Dependent and Plasminogen-Independent<br />
Pathways, 385<br />
Platelet activating fac<strong>to</strong>r<br />
Leukotriene B4 Mediates Shear Rate-Dependent Leukocyte<br />
Adhesion in Mesenteric Venules, 906<br />
Platelet aggregation<br />
Endothelium-Derived Relaxing Fac<strong>to</strong>r Modulates Platelet Aggregation<br />
in an In Vivo Model of Recurrent Platelet Activation,<br />
1447<br />
Platelet-derived growth fac<strong>to</strong>r<br />
Platelet-Derived Growth Fac<strong>to</strong>r Isoforms Decrease Insulin-like<br />
Growth Fac<strong>to</strong>r I Gene Expression in Rat Vascular Smooth<br />
Muscle Cells and Selectively Stimulate the Biosynthesis of<br />
Insulin-like Growth Fac<strong>to</strong>r Binding Protein 4, 646<br />
Rat Carotid Neointimal Smooth Muscle Cells Reexpress a<br />
Developmentally Regulated mRNA Phenotype During Repair<br />
of Arterial Injury, 759<br />
Regulation of Platelet-Derived Growth Fac<strong>to</strong>r Ligand and<br />
Recep<strong>to</strong>r Gene Expression by a-Thrombin in Vascular<br />
Smooth Muscle Cells, 1285<br />
Platelets<br />
Cod Liver Oil Alters Platelet-Arterial Wall Response <strong>to</strong> Injury<br />
in Pigs, 769<br />
Polarized light microscopy<br />
Accumulation and Assembly of Myosin in Hypertrophic Cardiomyopathy<br />
With the 403 Arg <strong>to</strong> Gln j3-Myosin Heavy Chain<br />
Mutation, 1404<br />
Postmi<strong>to</strong>tic cells<br />
Acidic and Basic Fibroblast Growth Fac<strong>to</strong>rs in Adult Rat Heart<br />
Myocytes: Localization, Regulation in Culture, and Effects on<br />
DNA Synthesis, 251<br />
Potassium<br />
Sympathetic Stimulation and Norepinephrine Infusion Modulate<br />
Extracellular Potassium Concentration During Acute<br />
Myocardial Ischemia, 1078<br />
Potassium conductance<br />
Positive Chronotropic Responses Induced by a1-Adrenergic<br />
Stimulation of Normal and "Ischemic" Purkinje Fibers Have<br />
Different Recep<strong>to</strong>r-Effec<strong>to</strong>r Coupling Mechanisms, 526<br />
Preconditioning<br />
Partial Coronary Stenosis Is Sufficient and Complete Reperfusion<br />
Is Manda<strong>to</strong>ry for Preconditioning the Canine Heart,<br />
1165<br />
Pressure natriuresis<br />
Relation Between Vasa Recta Blood Flow and Renal Interstitial<br />
Hydrostatic Pressure During Pressure Natriuresis, 1153<br />
Subject Index 1559<br />
Pressure overload<br />
Coronary Blood Flow After the Regression of Pressure-Overload<br />
Left Ventricular Hypertrophy, 1472<br />
Pressure-volume area<br />
Basal Metabolism Adds a Significant Offset <strong>to</strong> Unloaded Myocardial<br />
Oxygen Consumption per Minute, 414<br />
Pressure-volume relations<br />
Effect of Reduced Aortic Compliance on Cardiac Efficiency and<br />
Contractile Function of In Situ Canine Left Ventricle, 490<br />
Propagation<br />
Effects of 2,4-Dinitrophenol or Low [ATP]i on Cell Excitability<br />
and Action Potential Propagation in Guinea Pig Ventricular<br />
Myocytes, 821<br />
Prostaglandin D2<br />
Prostaglandin D2 Relaxes Bovine Coronary Arteries by Endothelium-Dependent<br />
Nitric Oxide-Mediated cGMP Formation,<br />
1305<br />
Prostaglandins<br />
Isolated Pulmonary Resistance Vessels From Fetal Lambs:<br />
Contractile Behavior and Responses <strong>to</strong> Indomethacin and<br />
Endothelin-1, 320<br />
Role of Endothelium-Derived Prostaglandins in Hypoxia-Elicited<br />
Arteriolar Dilation in Rat Skeletal Muscle, 790<br />
Protein degradation<br />
Physiological Hyperinsulinemia Inhibits Myocardial Protein<br />
Degradation In Vivo in the Canine Heart, 393<br />
Protein kinase A<br />
Angiotensin II Stimulates Two Myelin Basic Protein/Microtubule-Associated<br />
Protein 2 Kinases in Cultured Vascular<br />
Smooth Muscle Cells, 620<br />
Cardiac Sarcoplasmic Reticulum Chloride Channels Regulated<br />
by Protein Kinase A, 585<br />
Protein kinase C<br />
ar-Adrenocep<strong>to</strong>r Stimulation Enhances the Delayed Rectifier<br />
K' Current of Guinea Pig Ventricular Cells Through the<br />
Activation of Protein Kinase C, 1441<br />
Cellular Mechanisms for Synthesis and Secretion of Atrial<br />
Natriuretic Peptide and Brain Natriuretic Peptide in Cultured<br />
Rat Atrial Cells, 1039<br />
Endothelin-1 Enhances Calcium Entry Through T-Type Calcium<br />
Channels in Cultured Neonatal Rat Ventricular Myocytes,<br />
1242<br />
Endothelin Increases Myofilament Ca2' Sensitivity in a-Toxin-<br />
Permeabilized Rabbit Mesenteric Artery, 951<br />
Lysophosphatidylcholine Inhibits Surface Recep<strong>to</strong>r-Mediated<br />
Intracellular Signals in Endothelial Cells by a Pathway Involving<br />
Protein Kinase C Activation, 1422<br />
Proteolysis<br />
Cultured Rat Aortic Vascular Smooth Muscle Cells Digest<br />
Naturally Produced Extracellular Matrix: Involvement of<br />
Plasminogen-Dependent and Plasminogen-Independent<br />
Pathways, 385<br />
Pro<strong>to</strong>ns<br />
Reperfusion-Induced Arrhythmias: A Role for Washout of<br />
Extracellular Pro<strong>to</strong>ns? 1429<br />
Pseudomonas exo<strong>to</strong>xin<br />
In Vitro Effects of a Recombinant Toxin Targeted <strong>to</strong> the<br />
Fibroblast Growth Fac<strong>to</strong>r Recep<strong>to</strong>r on Rat Vascular Smooth<br />
Muscle and Endothelial Cells, 640<br />
Pseudostrain energy function<br />
Arterial Mechanics in Spontaneously Hypertensive Rats: Mechanical<br />
Properties, Hydraulic Conductivity, and Two-Phase<br />
(Solid/Fluid) Finite Element Models, 145<br />
Pulmonary circulation<br />
Maturation of Interdependence Between Extra-alveolar Arteries<br />
and Lung Parenchyma in Piglets, 701<br />
Pulmonary vascular resistance<br />
Isolated Pulmonary Resistance Vessels From Fetal Lambs:<br />
Contractile Behavior and Responses <strong>to</strong> Indomethacin and<br />
Endothelin-1, 320<br />
Purines<br />
Comprehensive Model of Transport and Metabolism of Adenosine<br />
and S-Adenosylhomocysteine in the Guinea Pig Heart,<br />
590
1560 <strong>Circulation</strong> <strong>Research</strong> Vol 71, No 6 December 1992<br />
Q<br />
QRS morphology<br />
Body Surface Mapping of Ec<strong>to</strong>pic Left Ventricular Activation:<br />
QRS Spectrum in Patients With Prior Myocardial Infarction,<br />
1361<br />
QX-222<br />
Inward Sodium Current at Resting Potentials in Single Cardiac<br />
Myocytes Induced by the Ischemic Metabolite Lysophosphatidylcholine,<br />
1231<br />
R<br />
Rabbit ventricular cells<br />
Inward Sodium Current at Resting Potentials in Single Cardiac<br />
Myocytes Induced by the Ischemic Metabolite Lysophosphatidylcholine,<br />
1231<br />
Rabbits<br />
Immunohis<strong>to</strong>chemical and Biochemical Evidence for a Cardiovascular<br />
Mineralocorticoid Recep<strong>to</strong>r, 503<br />
Radioactive microspheres<br />
Indirect Relation Between Rises in Oxygen Consumption and<br />
Left Ventricular Output at Birth in Lambs, 443<br />
Radioimmunoassay<br />
Suppression of Endothelin-1 Secretion by Lysophosphatidylcholine<br />
in Oxidized Low Density Lipoprotein in Cultured Vascular<br />
Endothelial Cells, 614<br />
Rat aortic smooth muscle<br />
Platelet-Derived Growth Fac<strong>to</strong>r-BB-Induced Suppression of<br />
Smooth Muscle Cell Differentiation, 1525<br />
Rat carotid artery<br />
Balloon Injury and Interleukin-1 ,3 Induce Nitric Oxide Synthase<br />
Activity in Rat Carotid Arteries, 331<br />
Rat heart function<br />
Effects of Norepinephrine on the Oxidative Pen<strong>to</strong>se Phosphate<br />
Pathway in the Rat Heart, 451<br />
Rat heart sarcolemmal membranes<br />
Depression of Cardiac Sarcolemmal Phospholipase D Activity<br />
by Oxidant-Induced Thiol Modification, 970<br />
Rat hearts<br />
Brain Death-Induced Impairment of Cardiac Contractile Performance<br />
Can Be Reversed by Explantation and May Not<br />
Preclude the Use of Hearts for Transplantation, 1213<br />
Dissociation Between Contractile Function and Oxidative Metabolism<br />
in Postischemic Myocardium: Attenuation by Ruthenium<br />
Red Administered During Reperfusion, 567<br />
Rat ventricular cells<br />
Inward Sodium Current at Resting Potentials in Single Cardiac<br />
Myocytes Induced by the Ischemic Metabolite Lysophosphatidylcholine,<br />
1231<br />
Rats<br />
Albumin Transport Characteristics of Rat Aorta in Early Phase<br />
of Hypertension, 932<br />
Effect of Caffeine on Expression of Cardiac Myosin Heavy<br />
Chain Gene in Adult Hypothyroid and Fetal Rats, 1031<br />
Reperfusion-Induced Arrhythmias: A Role for Washout of<br />
Extracellular Pro<strong>to</strong>ns? 1429<br />
Reentrant tachyarrhythmias<br />
Cholinergically Mediated Tachyarrhythmias Induced by a Single<br />
Extrastimulus in the Isolated Canine Right Atrium, 1254<br />
Reentry<br />
Reflection After Delayed Excitation in a Computer Model of a<br />
Single Fiber, 260<br />
Reflection<br />
Reflection After Delayed Excitation in a Computer Model of a<br />
Single Fiber, 260<br />
Reflow<br />
Correlation Between [5-3HJGlucose and [U-J4C]Deoxyglucose<br />
as Markers of Glycolysis in Reperfused Myocardium, 689<br />
Refrac<strong>to</strong>ry period<br />
Mechanism of Flecainide's Antiarrhythmic Action in Experimental<br />
Atrial Fibrillation, 271<br />
Regional ischemia<br />
Reperfusion-Induced Arrhythmias: A Role for Washout of<br />
Extracellular Pro<strong>to</strong>ns? 1429<br />
Regulation<br />
Identification and Characterization of Developmentally Regulated<br />
Genes in Vascular Smooth Muscle Cells, 711<br />
Renal artery<br />
Ionic Currents in Single Smooth Muscle Cells of the Canine<br />
Renal Artery, 745<br />
Renal hypertension<br />
Effect of Hypertension and Hypertrophy on Coronary Microvascular<br />
Pressure, 120<br />
Renal interstitial hydrostatic pressure<br />
Relation Between Vasa Recta Blood Flow and Renal Interstitial<br />
Hydrostatic Pressure During Pressure Natriuresis, 1153<br />
Renal sympathetic nerve activity<br />
Brain Ouabain-Like Activity and the Sympathoexcita<strong>to</strong>ry and<br />
Pressor Effects of Central Sodium in Rats, 1059<br />
Reoxygenation<br />
Relation of Mi<strong>to</strong>chondrial and Cy<strong>to</strong>solic Free Calcium <strong>to</strong><br />
Cardiac Myocyte Recovery After Exposure <strong>to</strong> Anoxia, 605<br />
Subcellular Electrolyte Alterations During Progressive Hypoxia<br />
and Following Reoxygenation in Isolated Neonatal Rat Ventricular<br />
Myocytes, 106<br />
Reperfusion<br />
Biomechanical Properties of Reperfused Transmural Myocardial<br />
Infarcts in Rabbits During the First Week After Infarction:<br />
Implications for Left Ventricular Rupture, 401<br />
Brain Death-Induced Impairment of Cardiac Contractile Performance<br />
Can Be Reversed by Explantation and May Not<br />
Preclude the Use of Hearts for Transplantation, 1213<br />
Changes in Intracellular Free Calcium Concentration During<br />
Long Exposures <strong>to</strong> Simulated Ischemia in Isolated Mammalian<br />
Ventricular Muscle, 58<br />
Decreased Myofilament Responsiveness in Myocardial Stunning<br />
Follows Transient Calcium Overload During Ischemia and<br />
Reperfusion, 1334<br />
Dissociation Between Contractile Function and Oxidative Metabolism<br />
in Postischemic Myocardium: Attenuation by Ruthenium<br />
Red Administered During Reperfusion, 567<br />
Effect of Ischemia and Reperfusion on Sarcoplasmic Reticulum<br />
Calcium Uptake, 1123<br />
Gap Junctional Conductance in Ventricular Myocyte Pairs<br />
Isolated From Postischemic Rabbit Myocardium, 127<br />
Hydrogen Peroxide-Induced Cardiovascular Reflexes: Role of<br />
Hydroxyl Radicals, 295<br />
Partial Coronary Stenosis Is Sufficient and Complete Reperfusion<br />
Is Manda<strong>to</strong>ry for Preconditioning the Canine Heart,<br />
1165<br />
Quantification of Hydroxyl Radical and Its Lack of Relevance <strong>to</strong><br />
Myocardial Injury During Early Reperfusion After Graded<br />
Ischemia in Rat Hearts, 96<br />
Superoxide Dismutase Enhances Ischemia-Induced Reactive<br />
Hyperemic Flow and Adenosine Release in Dogs: A Role of<br />
5'-Nucleotidase Activity, 558<br />
Reperfusion-induced arrhythmias<br />
Reperfusion-Induced Arrhythmias: A Role for Washout of<br />
Extracellular Pro<strong>to</strong>ns? 1429<br />
Reperfusion injury<br />
Effects of Complement Activation in the Isolated Heart: Role of<br />
the Terminal Complement Components, 303<br />
Kinetics of CSa Release in Lymph of Dogs Experiencing<br />
Coronary Artery Ischemia-Reperfusion Injury, 1518<br />
Restenosis<br />
In Vitro Effects of a Recombinant Toxin Targeted <strong>to</strong> the<br />
Fibroblast Growth Fac<strong>to</strong>r Recep<strong>to</strong>r on Rat Vascular Smooth<br />
Muscle and Endothelial Cells, 640<br />
Retrovirus<br />
Optimization of Retroviral Vec<strong>to</strong>r-Mediated Gene Transfer<br />
In<strong>to</strong> Endothelial Cells In Vitro, 1508<br />
Ruthenium red<br />
Effect of Perfusate [Ca2"] on Cardiac Sarcoplasmic Reticulum<br />
Ca2' Release Channel in Isolated Rat Hearts, 1049<br />
Ryanodine<br />
Effect of Perfusate [Ca2+] on Cardiac Sarcoplasmic Reticulum<br />
Ca2' Release Channel in Isolated Rat Hearts, 1049
Reperfusion Arrhythmias in Isolated Perfused Pig Hearts: Inhomogeneities<br />
in Extracellular Potassium, ST and TQ Potentials,<br />
and Transmembrane Action Potentials, 1131<br />
Ryanodine recep<strong>to</strong>r<br />
Differences in Cardiac Calcium Release Channel (Ryanodine<br />
Recep<strong>to</strong>r) Expression in Myocardium From Patients With<br />
End-Stage Heart Failure Caused by Ischemic Versus Dilated<br />
Cardiomyopathy, 18<br />
S<br />
Salicylic acid<br />
Quantification of Hydroxyl Radical and Its Lack of Relevance <strong>to</strong><br />
Myocardial Injury During Early Reperfusion After Graded<br />
Ischemia in Rat Hearts, 96<br />
Sarcoplasmic reticulum<br />
Cardiac Sarcoplasmic Reticulum Chloride Channels Regulated<br />
by Protein Kinase A, 585<br />
Effect of Ischemia and Reperfusion on Sarcoplasmic Reticulum<br />
Calcium Uptake, 1123<br />
Sarcoplasmic reticulum Ca2' release<br />
Positive Chronotropic Responses Induced by a1-Adrenergic<br />
Stimulation of Normal and "Ischemic" Purkinje Fibers Have<br />
Different Recep<strong>to</strong>r-Effec<strong>to</strong>r Coupling Mechanisms, 526<br />
Sero<strong>to</strong>nin<br />
Mechanism of Ergonovine-Induced Hyperconstriction of the<br />
Large Epicardial Coronary Artery in Conscious Dogs a<br />
Month After Arterial Injury, 435<br />
Single cardiomyocytes<br />
Developmental Changes in Long-Opening Behavior of L-Type<br />
Ca2' Channels in Embryonic Chick Heart Cells, 376<br />
Single-channel current<br />
Voltage-Dependent Gating and Single-Channel Conductance of<br />
Adult Mammalian Atrial Gap Junctions, 737<br />
Single-channel recording<br />
Cardiac Sarcoplasmic Reticulum Chloride Channels Regulated<br />
by Protein Kinase A, 585<br />
Sinus node<br />
Gap Junctional Channels in Adult Mammalian Sinus Nodal<br />
Cells: Immunolocalization and Electrophysiology, 229<br />
Site-directed mutagenesis<br />
Differential Effects of Elevating [K]. on Three Transient Outward<br />
Potassium Channels: Dependence on Channel Inactivation<br />
Mechanisms, 657<br />
Skeletal muscle arterioles<br />
Role of Endothelium-Derived Prostaglandins in Hypoxia-Elicited<br />
Arteriolar Dilation in Rat Skeletal Muscle, 790<br />
Smooth muscle<br />
Influence of Vascular Smooth Muscle Heterogeneity on Angiotensin<br />
Converting Enzyme Activity in Chicken Embryonic<br />
Aorta and in Endothelial Cells in Culture, 923<br />
Smooth muscle cell diversity<br />
Rat Carotid Neointimal Smooth Muscle Cells Reexpress a<br />
Developmentally Regulated mRNA Phenotype During Repair<br />
of Arterial Injury, 759<br />
Smooth muscle cell proliferation<br />
Platelet-Derived Growth Fac<strong>to</strong>r Suppresses and Fibroblast<br />
Growth Fac<strong>to</strong>r Enhances Cy<strong>to</strong>kine-Induced Production of<br />
Nitric Oxide by Cultured Smooth Muscle Cells: Effects on<br />
Cell Proliferation, 1088<br />
Regulation of Platelet-Derived Growth Fac<strong>to</strong>r Ligand and<br />
Recep<strong>to</strong>r Gene Expression by a-Thrombin in Vascular<br />
Smooth Muscle Cells, 1285<br />
Smooth muscle cells<br />
Coronary Collateral Development in Swine After Coronary<br />
Artery Occlusion, 1490<br />
Effects of External pH on Ionic Currents in Smooth Muscle<br />
Cells From the Basilar Artery of the Guinea Pig, 201<br />
Identification and Characterization of Developmentally Regulated<br />
Genes in Vascular Smooth Muscle Cells, 711<br />
Phenotype-Related Alteration in Expression of Natriuretic Peptide<br />
Recep<strong>to</strong>rs in Aortic Smooth Muscle Cells, 34<br />
Subject Index 1561<br />
SNARF-1<br />
Different Effects of a- and 13-Adrenergic Stimulation on Cy<strong>to</strong>solic<br />
pH and Myofilament Responsiveness <strong>to</strong> Ca2' in Cardiac<br />
Myocytes, 870<br />
Sodium<br />
Impaired Myogenic Responsiveness of Renal Microvessels in<br />
Dahl Salt-Sensitive Rats, 471<br />
Sodium current<br />
Characterization of the Sodium Current in Single Human Atrial<br />
Myocytes, 535<br />
Sodium pump<br />
Endothelial Modulation of the Ouabain-Induced Contraction in<br />
Human Placental Vessels, 943<br />
Regulation of Na,K-ATPase Gene Expression by Thyroid Hormone<br />
in Rat Cardiocytes, 1457<br />
Spontaneously hypertensive rats<br />
Age-Related Changes in Fibronectin Expression in Spontaneously<br />
Hypertensive, Wistar-Kyo<strong>to</strong>, and Wistar Rat Hearts,<br />
1341<br />
ST-TQ segment changes<br />
Reperfusion Arrhythmias in Isolated Perfused Pig Hearts: Inhomogeneities<br />
in Extracellular Potassium, ST and TQ Potentials,<br />
and Transmembrane Action Potentials, 1131<br />
Stiffness<br />
Effects of Cycling and Rigor Crossbridges on the Conformation<br />
of Cardiac Troponin C, 984<br />
Strahler ordering<br />
Branching Patterns in the Porcine Coronary Arterial Tree:<br />
Estimation of Flow Heterogeneity, 1200<br />
Stress<br />
aB-Crystallin in Cardiac Tissue: Association With Actin and<br />
Desmin Filaments, 288<br />
Stretch recep<strong>to</strong>rs<br />
Permeability of Rat Atrial Endocardium, Epicardium, and<br />
Myocardium <strong>to</strong> Large Molecules: Stretch-Dependent Effects,<br />
159<br />
Stunned myocardium<br />
Mechanisms of Subendocardial Dysfunction in Response <strong>to</strong><br />
Exercise in Dogs With Severe Left Ventricular Hypertrophy,<br />
423<br />
Pro<strong>to</strong>-oncogene Expression in Porcine Myocardium Subjected<br />
<strong>to</strong> Ischemia and Reperfusion, 1351<br />
Stunning<br />
Decreased Myofilament Responsiveness in Myocardial Stunning<br />
Follows Transient Calcium Overload During Ischemia and<br />
Reperfusion, 1334<br />
Subfragment-1<br />
Product Inhibition of the Ac<strong>to</strong>myosin Subfragment-1 ATPase in<br />
Skeletal, Cardiac, and Smooth Muscle, 1067<br />
Subtype<br />
Au<strong>to</strong>radiographic Characterization of ,B-Adrenergic Recep<strong>to</strong>r<br />
Subtype in the Canine Conduction System, 51<br />
Sympathetic coronary vasoconstriction<br />
Effect of Brief Myocardial Ischemia on Sympathetic Coronary<br />
Vasoconstriction, 960<br />
Sympathetic nervous system<br />
Sympathetic Stimulation and Norepinephrine Infusion Modulate<br />
Extracellular Potassium Concentration During Acute<br />
Myocardial Ischemia, 1078<br />
Sympathetic stimulation<br />
Mechanism of Hind Limb Vasoconstriction Due <strong>to</strong> Cyclosporin<br />
A in the Dog, 1159<br />
Synchronization<br />
Gap Junctional Channels in Adult Mammalian Sinus Nodal<br />
Cells: Immunolocalization and Electrophysiology, 229<br />
Synchronous openings<br />
Inward Sodium Current at Resting Potentials in Single Cardiac<br />
Myocytes Induced by the Ischemic Metabolite Lysophosphatidylcholine,<br />
1231
1562 <strong>Circulation</strong> <strong>Research</strong> Vol 71, No 6 December 1992<br />
T<br />
T-type calcium current<br />
Endothelin-1 Enhances Calcium Entry Through T-Type Calcium<br />
Channels in Cultured Neonatal Rat Ventricular Myocytes,<br />
1242<br />
Tachycardia<br />
Relation Between Ventricular and Myocyte Function With<br />
Tachycardia-Induced Cardiomyopathy, 174<br />
Tear threshold<br />
Biomechanical Properties of Reperfused Transmural Myocardial<br />
Infarcts in Rabbits During the First Week After Infarction:<br />
Implications for Left Ventricular Rupture, 401<br />
Tethered ligand<br />
Thrombin Recep<strong>to</strong>r 14-Amino Acid Peptide Mediates Endothelial<br />
Hyperadhesivity and Neutrophil Adhesion by P-Selectin-Dependent<br />
Mechanism, 1015<br />
Tetrodo<strong>to</strong>xin<br />
Characterization of the Sodium Current in Single Human Atrial<br />
Myocytes, 535<br />
Theophylline<br />
Effect of Caffeine on Expression of Cardiac Myosin Heavy<br />
Chain Gene in Adult Hypothyroid and Fetal Rats, 1031<br />
Extracellular and Intracellular Actions of Adenosine and Related<br />
Compounds in the Reperfused Rat Intestine, 720<br />
Thiol groups<br />
Depression of Cardiac Sarcolemmal Phospholipase D Activity<br />
by Oxidant-Induced Thiol Modification, 970<br />
a-Thrombin<br />
Regulation of Platelet-Derived Growth Fac<strong>to</strong>r Ligand and<br />
Recep<strong>to</strong>r Gene Expression by a-Thrombin in Vascular<br />
Smooth Muscle Cells, 1285<br />
Thrombin Recep<strong>to</strong>r 14-Amino Acid Peptide Mediates Endothelial<br />
Hyperadhesivity and Neutrophil Adhesion by P-Selectin-Dependent<br />
Mechanism, 1015<br />
Thrombin recep<strong>to</strong>r<br />
Thrombin Recep<strong>to</strong>r 14-Amino Acid Peptide Mediates Endothelial<br />
Hyperadhesivity and Neutrophil Adhesion by P-Selectin-Dependent<br />
Mechanism, 1015<br />
Thrombogenic site<br />
Heparin Adheres <strong>to</strong> the Damaged Arterial Wall and Inhibits Its<br />
Thrombogenicity, 577<br />
Thrombosis<br />
Heparin Adheres <strong>to</strong> the Damaged Arterial Wall and Inhibits Its<br />
Thrombogenicity, 577<br />
Thyroid hormone<br />
Decreased Collagen Gene Expression and Absence of Fibrosis<br />
in Thyroid Hormone-Induced Myocardial Hypertrophy: Response<br />
of Cardiac Fibroblasts <strong>to</strong> Thyroid Hormone In Vitro,<br />
831<br />
Regulation of Na,K-ATPase Gene Expression by Thyroid Hormone<br />
in Rat Cardiocytes, 1457<br />
Tight junctions<br />
Permeability of Rat Atrial Endocardium, Epicardium, and<br />
Myocardium <strong>to</strong> Large Molecules: Stretch-Dependent Effects,<br />
159<br />
Tissue<br />
Acidic and Basic Fibroblast Growth Fac<strong>to</strong>rs in Adult Rat Heart<br />
Myocytes: Localization, Regulation in Culture, and Effects on<br />
DNA Synthesis, 251<br />
Topology<br />
Branching Patterns in the Porcine Coronary Arterial Tree:<br />
Estimation of Flow Heterogeneity, 1200<br />
Transcy<strong>to</strong>sis<br />
Permeability of Rat Atrial Endocardium, Epicardium, and<br />
Myocardium <strong>to</strong> Large Molecules: Stretch-Dependent Effects,<br />
159<br />
Transendothelial transport<br />
Measurement of Endothelial Permeability <strong>to</strong> '25I-Low Density<br />
Lipoproteins in Rabbit Arteries by Use of En Face Preparations,<br />
883<br />
Transient outward current<br />
Age-Related Appearance of Outward Currents May Contribute<br />
<strong>to</strong> Developmental Differences in Ventricular Repolarization,<br />
1390<br />
Functional Expression of an Inactivating Potassium Channel<br />
Cloned From Human Heart, 732<br />
Transmembrane potential<br />
Reperfusion Arrhythmias in Isolated Perfused Pig Hearts: Inhomogeneities<br />
in Extracellular Potassium, ST and TQ Potentials,<br />
and Transmembrane Action Potentials, 1131<br />
Transmembrane potentials<br />
Persisting Zones of Slow Impulse Conduction in Developing<br />
Chicken Hearts, 240<br />
Transmethylation<br />
Comprehensive Model of Transport and Metabolism of Adenosine<br />
and S-Adenosylhomocysteine in the Guinea Pig Heart,<br />
590<br />
Tropoelastin<br />
Rat Carotid Neointimal Smooth Muscle Cells Reexpress a<br />
Developmentally Regulated mRNA Phenotype During Repair<br />
of Arterial Injury, 759<br />
ar-Tropomyosin<br />
Platelet-Derived Growth Fac<strong>to</strong>r-BB-Induced Suppression of<br />
Smooth Muscle Cell Differentiation, 1525<br />
Troponin C<br />
Effects of Cycling and Rigor Crossbridges on the Conformation<br />
of Cardiac Troponin C, 984<br />
Tumor necrosis fac<strong>to</strong>r<br />
Interferon-y and Tumor Necrosis Fac<strong>to</strong>r Synergize <strong>to</strong> Induce<br />
Nitric Oxide Production and Inhibit Mi<strong>to</strong>chondrial Respiration<br />
in Vascular Smooth Muscle Cells, 1268<br />
Two-phase media<br />
Arterial Mechanics in Spontaneously Hypertensive Rats: Mechanical<br />
Properties, Hydraulic Conductivity, and Two-Phase<br />
(Solid/Fluid) Finite Element Models, 145<br />
Tyrosine phosphorylation<br />
Angiotensin II Stimulates Two Myelin Basic Protein/Microtubule-Associated<br />
Protein 2 Kinases in Cultured Vascular<br />
Smooth Muscle Cells, 620<br />
U<br />
Ultrastructure<br />
Relation Between Ventricular and Myocyte<br />
Tachycardia-Induced Cardiomyopathy, 174<br />
Function With<br />
V<br />
Vagus nerves<br />
Sequence of Excitation as a Fac<strong>to</strong>r in Sympathetic-Parasympathetic<br />
Interactions in the Heart, 898<br />
Vasa recta<br />
Relation Between Vasa Recta Blood Flow and Renal Interstitial<br />
Hydrostatic Pressure During Pressure Natriuresis, 1153<br />
Vascular damage<br />
Heparin Adheres <strong>to</strong> the Damaged Arterial Wall and Inhibits Its<br />
Thrombogenicity, 577<br />
Vascular endothelium<br />
Lysophosphatidylcholine Inhibits Bradykinin-Induced Phosphoinositide<br />
Hydrolysis and Calcium Transients in Cultured<br />
Bovine Aortic Endothelial Cells, 1410<br />
Vascular smooth muscle<br />
Culture of Renal Arteriolar Smooth Muscle Cells: Mi<strong>to</strong>genic<br />
Responses <strong>to</strong> Angiotensin II, 1143<br />
Cultured Rat Aortic Vascular Smooth Muscle Cells Digest<br />
Naturally Produced Extracellular Matrix: Involvement of<br />
Plasminogen-Dependent and Plasminogen-Independent<br />
Pathways, 385<br />
Endothelin Increases Myofilament Ca2+ Sensitivity in a-Toxin-<br />
Permeabilized Rabbit Mesenteric Artery, 951<br />
Interferon-y and Tumor Necrosis Fac<strong>to</strong>r Synergize <strong>to</strong> Induce<br />
Nitric Oxide Production and Inhibit Mi<strong>to</strong>chondrial Respiration<br />
in Vascular Smooth Muscle Cells, 1268<br />
Ionic Currents in Single Smooth Muscle Cells of the Canine<br />
Renal Artery, 745<br />
Mechanisms of Vasodilation Induced by NKH477, a Water-<br />
Soluble Forskolin Derivative, in Smooth Muscle of the Porcine<br />
Coronary Artery, 70<br />
Potentiation of Endothelium-Dependent Relaxations <strong>to</strong> Bradykinin<br />
by Angiotensin I Converting Enzyme Inhibi<strong>to</strong>rs in
Canine Coronary Artery Involves Both Endothelium-Derived<br />
Relaxing and Hyperpolarizing Fac<strong>to</strong>rs, 137<br />
Role of Endothelium-Derived Prostaglandins in Hypoxia-Elicited<br />
Arteriolar Dilation in Rat Skeletal Muscle, 790<br />
Vascular smooth muscle cells<br />
Angiotensin II Stimulates Two Myelin Basic Protein/Microtubule-Associated<br />
Protein 2 Kinases in Cultured Vascular<br />
Smooth Muscle Cells, 620<br />
In Vitro Effects of a Recombinant Toxin Targeted <strong>to</strong> the<br />
Fibroblast Growth Fac<strong>to</strong>r Recep<strong>to</strong>r on Rat Vascular Smooth<br />
Muscle and Endothelial Cells, 640<br />
Platelet-Derived Growth Fac<strong>to</strong>r Isoforms Decrease Insulin-like<br />
Growth Fac<strong>to</strong>r I Gene Expression in Rat Vascular Smooth<br />
Muscle Cells and Selectively Stimulate the Biosynthesis of<br />
Insulin-like Growth Fac<strong>to</strong>r Binding Protein 4, 646<br />
Vasorelaxation<br />
Effects on the Rabbit Coronary Artery of LP-805, a New Type<br />
of Releaser of Endothelium-Derived Relaxing Fac<strong>to</strong>r and a<br />
K' Channel Opener, 859<br />
Veins<br />
Intraluminal Flow Increases Vascular Tone and 45Ca21 Influx in<br />
the Rabbit Facial Vein, 339<br />
Ventricular arrhythmias<br />
Body Surface Mapping of Ec<strong>to</strong>pic Left Ventricular Activation:<br />
QRS Spectrum in Patients With Prior Myocardial Infarction,<br />
1361<br />
Ventricular arterial matching<br />
Mechanical Matching of the Left Ventricle With the Arterial<br />
System in Exercising Dogs, 481<br />
Ventricular energetics<br />
Basal Metabolism Adds a Significant Offset <strong>to</strong> Unloaded Myocardial<br />
Oxygen Consumption per Minute, 414<br />
Ventricular fibrillation<br />
Myocardial Energetics During Ventricular Fibrillation Investigated<br />
by Magnetization Transfer Nuclear Magnetic Resonance<br />
Spectroscopy, 1111<br />
Reperfusion-Induced Arrhythmias: A Role for Washout of<br />
Extracellular Pro<strong>to</strong>ns? 1429<br />
Ventricular function<br />
Effect of Reduced Aortic Compliance on Cardiac Efficiency and<br />
Contractile Function of In Situ Canine Left Ventricle, 490<br />
Relation Between Ventricular and Myocyte Function With<br />
Tachycardia-Induced Cardiomyopathy, 174<br />
Ventricular hypertrophy<br />
Coronary Blood Flow After the Regression of Pressure-Overload<br />
Left Ventricular Hypertrophy, 1472<br />
Ventricular myocytes<br />
Effects of 2,4-Dinitrophenol or Low [ATP]i on Cell Excitability<br />
and Action Potential Propagation in Guinea Pig Ventricular<br />
Myocytes, 821<br />
Subject Index 1563<br />
Verapamil Diminishes Action Potential Changes During Metabolic<br />
Inhibition by Blocking ATP-Regulated Potassium Currents,<br />
87<br />
Ventricular repolarization<br />
Age-Related Appearance of Outward Currents May Contribute<br />
<strong>to</strong> Developmental Differences in Ventricular Repolarization,<br />
1390<br />
Ventriculovascular coupling<br />
Effect of Reduced Aortic Compliance on Cardiac Efficiency and<br />
Contractile Function of In Situ Canine Left Ventricle, 490<br />
Venules<br />
Interaction Between Microvascular al- and a2-Adrenocep<strong>to</strong>rs<br />
and Endothelium-Derived Relaxing Fac<strong>to</strong>r, 188<br />
Vessel <strong>to</strong>ne<br />
Prostaglandin D2 Relaxes Bovine Coronary Arteries by Endothelium-Dependent<br />
Nitric Oxide-Mediated cGMP Formation,<br />
1305<br />
Voltage dependence<br />
Voltage-Dependent Gating and Single-Channel Conductance of<br />
Adult Mammalian Atrial Gap Junctions, 737<br />
Volume conduc<strong>to</strong>r<br />
A Model Study of Volume Conduc<strong>to</strong>r Effects on Endocardial<br />
and Intracavitary Potentials, 511<br />
W<br />
Wall thickness<br />
Mechanisms of Subendocardial Dysfunction in Response <strong>to</strong><br />
Exercise in Dogs With Severe Left Ventricular Hypertrophy,<br />
423<br />
Whole-cell voltage clamp<br />
Characterization of the Sodium Current in Single Human Atrial<br />
Myocytes, 535<br />
Wistar rats<br />
Age-Related Changes in Fibronectin Expression in Spontaneously<br />
Hypertensive, Wistar-Kyo<strong>to</strong>, and Wistar Rat Hearts,<br />
1341<br />
X<br />
X-ray microanalysis<br />
Subcellular Electrolyte Alterations During Progressive Hypoxia<br />
and Following Reoxygenation in Isolated Neonatal Rat Ventricular<br />
Myocytes, 106<br />
Xenopus oocytes<br />
Differential Effects of Elevating [K], on Three Transient Outward<br />
Potassium Channels: Dependence on Channel Inactivation<br />
Mechanisms, 657<br />
z<br />
ZK 110.841<br />
Prostaglandin D2 Relaxes Bovine Coronary Arteries by Endothelium-Dependent<br />
Nitric Oxide-Mediated cGMP Formation,<br />
1305
NEWS<br />
From the <strong>American</strong> Heart Association<br />
1991-1992 Pharmaceutical<br />
Roundtable Contributions<br />
Four years ago, in an all-out effort <strong>to</strong> solve the<br />
problem of promising research projects going unfunded,<br />
the <strong>American</strong> Heart Association joined<br />
with several leading drug companies <strong>to</strong> form the<br />
AHA Pharmaceutical Roundtable.<br />
The original founding member companies<br />
agreed <strong>to</strong> contribute $300,000 annually for at least<br />
5 years <strong>to</strong> support cardiovascular research. The<br />
regular members provide yearly payments of<br />
$200,000.<br />
Those original member companies and the two<br />
that have joined since 1988 will by the end of fiscal<br />
year 1992-1993 have given a <strong>to</strong>tal of $11.5 million<br />
<strong>to</strong> the AHA <strong>to</strong> support research in<strong>to</strong> better ways <strong>to</strong><br />
prevent and treat heart and blood vessel diseases.<br />
But many of those same companies have provided<br />
additional funds for several AHA educational<br />
and research programs:<br />
* Boehringer Ingelheim Pharmaceuticals Inc.<br />
contributed <strong>to</strong> the National Center Heritage Walk<br />
project.<br />
* Bris<strong>to</strong>l-Myers Squibb Corp. expanded the lipid<br />
disorders training centers <strong>to</strong> include training for<br />
foreign physicians. The company also sponsored<br />
the scientific conference "Prevention III - Behavior<br />
Change and Compliance: Keys <strong>to</strong> Cardiovascular<br />
Health."<br />
* CIBA-GEIGY Corp. provided support for<br />
shuttle service at Scientific Sessions.<br />
* Genentech Inc. contributed <strong>to</strong> the National<br />
Center Heritage Walk project and provided support<br />
for the scientific conference "Peripheral Vascular<br />
Disease." The company also provided support<br />
for the prelimary booklet, premeeting paper,<br />
and the <strong>American</strong> Heart Today television program<br />
and daily newspaper for the 1992 Scientific Sessions.<br />
Genentech also provided support for the<br />
international lounge at the meeting.<br />
* Parke-Davis Division of Warner-Lambert Co.<br />
provided funding for a Clinician-Scientist Award<br />
in Lipoproteins.<br />
* SmithKline Beecham Pharmaceuticals (Clinical<br />
Labora<strong>to</strong>ries and Consumer Brands Divisions)<br />
underwrote the cost of production and distribution<br />
of the Risk Fac<strong>to</strong>r Prediction Kit <strong>to</strong> physicians<br />
throughout the country.<br />
* Sandoz Pharmaceuticals Corp. contributed <strong>to</strong><br />
the National Center Heritage Walk project. The<br />
company also provided support for the medical<br />
education meeting "Atherosclerosis, Thrombosis,<br />
and Proliferation" and for a nutrition slide kit<br />
A1564<br />
for medical professionals <strong>to</strong> use at speaking<br />
engagements.<br />
* Sanofi Winthrop Pharmaceuticals/Division of<br />
Sterling Winthrop Inc. contributed <strong>to</strong> the National<br />
Center Heritage Walk project.<br />
* Wyeth-Ayerst Labora<strong>to</strong>ries provided support<br />
for the television program <strong>American</strong> Heart Today<br />
and daily newspaper for the 1992 Scientific Sessions.<br />
The company also provided support for the<br />
message center at the meeting.<br />
In addition, all members of the Roundtable<br />
contributed funding for the new program "Science,<br />
<strong>Research</strong> and Tomorrow." This national<br />
awareness program includes an 11-minute video,<br />
the booklet "Understanding a Scientist," and a<br />
science promotion guide for affiliates and divisions.<br />
This program was introduced <strong>to</strong> affiliates at<br />
the 1992 Enterprise Conference. Production plans<br />
for next year include two brochures and a researcher<br />
slide presentation kit.<br />
This consortium has made notable contributions<br />
<strong>to</strong> the AHA in the past year. Such contributions by<br />
all nine members <strong>to</strong>tal more than $4.7 million for<br />
1991-1992.<br />
AHA Announces New National<br />
<strong>Research</strong> Awards<br />
The AHA's National Center <strong>Research</strong> Program<br />
is providing research support <strong>to</strong> 333 new awardees<br />
in 1992-1993 and has committed $51.4 million <strong>to</strong><br />
support these new awards for the next 1-5 years.<br />
The AHA continues <strong>to</strong> support an additional 685<br />
awards that were initiated from 1988 through 1991.<br />
The AHA's National Center <strong>Research</strong> Program<br />
supports two types of awards: project support<br />
awards and salary support awards. Project support<br />
awards, or grants-in-aid, are used <strong>to</strong> purchase<br />
supplies and equipment and other items needed <strong>to</strong><br />
test a specific hypothesis. Of the 333 new awardees,<br />
180 are receiving grants-in-aid. Salary support<br />
awards pay all or part of an individual's salary<br />
while that individual develops the skills and experience<br />
needed <strong>to</strong> initiate or develop a career as an<br />
independent scientific investiga<strong>to</strong>r. One hundred<br />
and fifty-three of the new awards for 1992-1993<br />
provide salary support.<br />
Several salary support awards are offered by the<br />
AHA's National Center <strong>Research</strong> Program. These<br />
include Medical Student <strong>Research</strong> Fellowships<br />
(fourteen new institutional awards in 1992-1993),<br />
International <strong>Research</strong> Fellowships (nine new<br />
awards in 1992-1993), Minority Scientist Development<br />
Awards (five new awards in 1992-1993),
Clinician-Scientist Awards (15 new awards in<br />
1992-1993) and Established Investiga<strong>to</strong>rships (60<br />
new awards in 1992-1993).<br />
In addition <strong>to</strong> the projects funded by the national<br />
research program, AHA affiliates throughout<br />
the United States are supporting scientific<br />
research projects by funding 1,279 new and 597<br />
continuing awards in 1992-1993.<br />
The newly funded awards for 1992-1993 will<br />
support research in the broad field of cardiovascular<br />
function and disease as well as stroke. Arteriosclerosis,<br />
behavioral medicine, cerebral circulation<br />
and cerebrovascular disease, electrophysiology,<br />
epidemiology, genes and gene regulation, heart<br />
failure, hypertension, kidney properties, lipid metabolism,<br />
nutrition, preventive medicine, pulmonary<br />
function, thrombosis and properties of the<br />
vascular wall are some of the areas being explored<br />
by the investiga<strong>to</strong>rs who are supported through<br />
these AHA awards.<br />
The names of the new 1992-1993 national research<br />
program awardees, the titles of their<br />
projects, their institutions, and approved award<br />
periods are available on request. Contact the Division<br />
of <strong>Research</strong> Administration, <strong>American</strong><br />
Heart Association, 7272 Greenville Avenue, Dallas,<br />
TX 75231-4596. Telephone 214-706-1450. Fax<br />
214-706-1341.<br />
AHA Affiliates Fund 1,279<br />
New <strong>Research</strong> Awards<br />
The AHA's 56 affiliates offer a variety of research<br />
awards that enable talented individuals <strong>to</strong><br />
conduct research in cardiovascular function and<br />
disease, including stroke. In 1992-1993 affiliate<br />
research programs throughout the United States<br />
are supporting 1,279 new research awards. In<br />
addition, affiliates continue <strong>to</strong> support another 597<br />
continuing awards that were initiated in previous<br />
years. This amounts <strong>to</strong> a <strong>to</strong>tal investment of $46.2<br />
million for 1992-1993.<br />
Each AHA affiliate channels at least 30% of<br />
every publicly donated dollar in<strong>to</strong> research. Fifteen<br />
percent of each dollar goes <strong>to</strong> support the<br />
AHA's national research programs, and another<br />
15% or more supports the affiliate's own research<br />
programs. Affiliate programs vary according <strong>to</strong><br />
local needs and affiliate resources. As with national<br />
programs, they provide salary support, project<br />
support, or both.<br />
The most common affiliate programs are grantsin-aid<br />
and fellowships. Grants support high-quality<br />
research projects; fellowships are intended <strong>to</strong><br />
NEWS<br />
A1565<br />
foster interest in, provide training for, and encourage<br />
the pursuit of research careers. In 1992-1993<br />
affiliates are investing $31.1 million <strong>to</strong> support<br />
1,134 new and continuing grants and an additional<br />
$11.3 million <strong>to</strong> fund 420 new and continuing<br />
fellowships.<br />
Affiliates also fund other, more specialized<br />
awards. In 1992-1993 affiliates will pay an estimated<br />
$1.4 million <strong>to</strong> fund 283 student awards.<br />
These awards help encourage students <strong>to</strong> consider<br />
careers in scientific research. In addition, affiliates<br />
will pay out an estimated $1.5 million <strong>to</strong> support 39<br />
new and continuing awards <strong>to</strong> support teams of<br />
researchers working <strong>to</strong>ward a common scientific<br />
goal or <strong>to</strong> help established researchers who wish <strong>to</strong><br />
explore new research directions. Finally, affiliates<br />
are sharing financial support of 25 new national<br />
awards in 1992-1993 with a <strong>to</strong>tal investment of<br />
$548,917.<br />
In addition <strong>to</strong> the affiliate research programs,<br />
the AHA national program is supporting 1,018<br />
new and continuing research awards in 1992-1993,<br />
with a <strong>to</strong>tal investment of $43.3 million for this<br />
period.<br />
The names of the new 1992-1993 affiliate research<br />
program awardees, the titles of their<br />
projects, and their institutions are available on<br />
request. Contact the Division of <strong>Research</strong> Administration,<br />
<strong>American</strong> Heart Association, 7272<br />
Greenville Avenue, Dallas, TX 75231-4596. Telephone<br />
214-706-1450. Fax 214-706-1341.<br />
New Television Series Targets<br />
Primary Care Physicians<br />
"Heart Disease and Stroke," a new television<br />
series based on the <strong>American</strong> Heart Association<br />
journal of the same name, will begin airing in<br />
January 1993.<br />
"The programs are an innovative way <strong>to</strong> reach<br />
primary care physicians and nurses with the most<br />
current information on heart disease and stroke,"<br />
said J. Willis Hurst, MD, edi<strong>to</strong>r-in-chief of the<br />
journal. Dr. Hurst, a past president of the AHA,<br />
will host the upcoming series.<br />
Unlike most scientific journals, Heart Disease<br />
and Stroke focuses on state-of-the-art medical<br />
approaches and developments in prevention and<br />
treatment rather than original research. "We hope<br />
<strong>to</strong> provide health professionals with information<br />
they can actually apply in their practices," said Dr.<br />
Hurst.<br />
The series will air every Saturday and Sunday on<br />
CNBC as a production of <strong>American</strong> Medical Tele-
vision. Each half-hour program will include a<br />
summary of an article from the journal, comments<br />
from Dr. Hurst and the article's author, and a<br />
discussion of patient cases and their management.<br />
Program videocassettes will be offered <strong>to</strong> the<br />
560 accredited US medical schools and teaching<br />
hospitals and will be available for subscription or<br />
single-copy purchase. Reprints of journal articles<br />
on which the programs are based will also be<br />
available.<br />
Publications Available<br />
From the AHA<br />
We Offer a Special Incentive for Learning Stroke's<br />
Warning Signs. It's Called Life. This 11" by 17" color<br />
poster may be displayed at work, community,<br />
health, and school sites. It may also be used <strong>to</strong><br />
promote special <strong>American</strong> Heart Month events<br />
throughout February. In English, Order No. 01-<br />
4176; in Spanish, Order No. 01-4177.<br />
A Guide <strong>to</strong> Losing Weight. This brief, easy-<strong>to</strong>read<br />
pamphlet gives the AHA's recommendations<br />
for reducing weight on a fat-controlled, nutritious<br />
eating plan. In English, Order No. 50-1035; in<br />
Spanish, Order No. 50-1036.<br />
About Heart Transplants. Cardiac transplantations,<br />
donor selection, and expectations of the<br />
recipient after transplant are discussed in this<br />
pamphlet, as are future directions in cardiac transplantion.<br />
Order No. 50-1111.<br />
About Your Heart and Exercise. This updated<br />
booklet provides valuable information about cardiovascular<br />
fitness, types of exercise, and choosing<br />
an exercise program. It includes an exercise record<br />
<strong>to</strong> allow daily recording of activity. Order No.<br />
51-1038. (Related materials: About Your Heart and<br />
Blood Pressure, Order No. 51-03B; About Your<br />
Heart and Bloodstream, Order No. 51-031A; About<br />
Your Heart and Diet, Order No. 51-040A; andAbout<br />
Your Heart and Smoking, Order No. 51-037A.)<br />
Healthy Heart Food Chart. In Spanish. This 17"<br />
by 22" nutrition poster fits on a refrigera<strong>to</strong>r door<br />
and gives consumers information at a glance about<br />
the number of calories and grams of fat, saturated<br />
fat, and cholesterol in commonly eaten foods. It<br />
also gives consumers information needed <strong>to</strong> calculate<br />
their daily fat and calorie allowances.<br />
Making Mexican Food "Heart Healthy"/C6mo<br />
hace comida mexicana "saludable para el corazon. "<br />
This brochure, originally developed by the New<br />
Mexico affiliate of the AlA, gives tips on adapting<br />
traditional Mexican recipes <strong>to</strong> lower their fat con-<br />
NEWS<br />
A1566<br />
tent. It is printed in Spanish on one side and<br />
English on the other. Order No. 64-8075.<br />
National Council on Patient<br />
Information and Education<br />
Dr. Reginald L. Washing<strong>to</strong>n is the AHA's representative<br />
on the board of direc<strong>to</strong>rs of the National<br />
Council on Patient Information and Education.<br />
The goal of the NCPIE is <strong>to</strong> help patients<br />
work with health care providers and follow medication<br />
therapy safely and effectively.<br />
The NCPIE was formed <strong>to</strong> increase consumers'<br />
awareness of their right and need for information<br />
about prescription medicines, the availability of<br />
such information, and how <strong>to</strong> obtain it. The council<br />
also works <strong>to</strong> increase health professionals'<br />
awareness of the need <strong>to</strong> give more and better<br />
information about drug therapy and the availability<br />
of information and educational resources <strong>to</strong> use<br />
in their practices.<br />
According <strong>to</strong> the NCPIE, up <strong>to</strong> half of the 1.7<br />
billion prescriptions dispensed in the United<br />
States each year are used incorrectly because of<br />
poor patient-provider communication, use of multiple<br />
medicines or multiple health care providers,<br />
inability <strong>to</strong> take medication as prescribed, deliberate<br />
noncompliance, or altered drug action and<br />
response due <strong>to</strong> aging. The consequences of incorrect<br />
medicine use can be prolonged illness, avoidable<br />
side effects, drug interactions, increased hospitalization,<br />
absences from work, overutilization of<br />
health care services, and even death.<br />
To combat this problem, the NCPIE is conducting<br />
national education programs <strong>to</strong> improve communication<br />
about prescription medicines. Specific<br />
patient populations and health care professionals<br />
will be targeted in these television, radio, and print<br />
campaigns. The council is also sponsoring Talk<br />
About Prescriptions Month and the National<br />
Brown Bag Medicine Review Program, which is<br />
designed <strong>to</strong> encourage health care providers and<br />
community organizations <strong>to</strong> help older patients<br />
who take multiple medications. Other activities of<br />
the NCPIE include preparing major research reports<br />
on medication misuse in the United States<br />
and hosting the National Conference on Prescription<br />
Medicine Information and Education.<br />
For more information, call 202-347-6711.<br />
1993 Gordon <strong>Research</strong> Conference<br />
The 1993 Gordon <strong>Research</strong> Conference on Angiotensin,<br />
which had been canceled, will be held as
previously scheduled on February 8-12, 1993, at<br />
Casa Sirena Resort, Oxnard, Calif. For information<br />
contact William F. Ganong, MD, Department<br />
of Physiology, University of California, San Francisco,<br />
CA 94143-0444. Telephone 415-476-1869.<br />
Fax 415-476-4929.<br />
Grants and Contracts<br />
Training Course<br />
The Office of the Assistant Secretary of Health<br />
announces a training course, "Orientation <strong>to</strong> Public<br />
Health Service Grants and Contracts Activities<br />
for Applicants and Recipients of Awards," which<br />
will be presented at locations around the country.<br />
The target audience is grant and contract staff of<br />
organizations presently doing business with the<br />
PHS or planning <strong>to</strong> submit applications for grants<br />
or proposals for contracts. The course, intended<br />
for staff who are inexperienced with the grant and<br />
contract mechanism, is designed <strong>to</strong> provide a<br />
broad overview of how <strong>to</strong> conduct business with<br />
the PHS using the grant and contract mechanisms.<br />
It is not a course on grant writing.<br />
During the two days of the course, applicants for<br />
and recipients of PHS grants and contracts will<br />
learn about the procedures and expectations of<br />
applying for funding and administering an award<br />
from the PHS.<br />
January 10 is the application deadline for<br />
courses held in the following cities: Kansas City,<br />
Mo. (February 22-23); Dallas, Tex. (March 17-<br />
18); San Francisco, Calif. (April 19-20); and Seattle,<br />
Wash. (May 17-18). May 10 is the deadline<br />
for the courses held in Rockville, Md. (June<br />
15-16); Bos<strong>to</strong>n, Mass. (July 12-13); Chicago, Ill.<br />
(August 16-17), and Denver, Colo. (September<br />
NEWS<br />
A1567<br />
20-21). Selection will be on a first-come, firstserved<br />
basis.<br />
To apply, send a letter on the employing organization's<br />
letterhead <strong>to</strong> the training coordina<strong>to</strong>r<br />
with the following information: name of applicant;<br />
employing organization (name, address, telephone<br />
number); position title of applicant, years of experience<br />
with PHS grants, contracts, or both; principal<br />
area of interest (grants, contracts, or both);<br />
reason for wanting <strong>to</strong> take the course in 100 words<br />
or less; and the course session desired. Requests<br />
for information as well as letters of application<br />
should be sent <strong>to</strong> Training Coordina<strong>to</strong>r, Grants<br />
Policy Branch, Division of Grants and Contracts,<br />
Office of the Assistant Secretary for Health, Parklawn<br />
Building, Room 17A-45, 5600 Fishers Lane,<br />
Rockville, MD 20857.<br />
Reentry In<strong>to</strong> the<br />
Neurological Sciences<br />
The National Institute of Neurological Disorders<br />
and Stroke program for reentry in<strong>to</strong> the<br />
neurological sciences is designed <strong>to</strong> assist basic<br />
and clinical neurological scientists whose careers<br />
have had a 3- <strong>to</strong> 8-year interruption. It is a<br />
postdoc<strong>to</strong>ral award <strong>to</strong> support individuals with<br />
high potential for careers as independent investiga<strong>to</strong>rs<br />
in basic or clinical research, providing them<br />
with the opportunity <strong>to</strong> pursue a research project<br />
and update research skills, learn new techniques,<br />
and obtain any other experience necessary <strong>to</strong><br />
reentering active careers in science and academic<br />
medicine.<br />
For a copy of the program guidelines, contact<br />
Mr. Edward M. Donohue, Deputy Direc<strong>to</strong>r, Division<br />
of Extramural Activities, National Institute of<br />
Neurological Disorders and Stroke, Bethesda, MD<br />
20892. Telephone 301-496-4188.
Domestic<br />
1992<br />
Indicates meetings sponsored or hosted by the<br />
<strong>American</strong> Heart Association or its scientific councils.<br />
Dec 1-4: Clinical Cardiac Electrophysiology, Pacemakers,<br />
and Cardioverter/Defibrilla<strong>to</strong>rs. Bethesda, Md.<br />
Douglas P. Zipes, MD, direc<strong>to</strong>r. Inquiries: <strong>American</strong><br />
College of Cardiology, Heart House Learning Center,<br />
9111 Old George<strong>to</strong>wn Rd, Bethesda, MD 20814-<br />
1699. Tel 800-257-4737 or 301-897-2653. Fax 301-<br />
897-9745.<br />
Dec 7-9: Progress in Angioscopy, Interventional Techniques,<br />
and Vascular Surgery 1992. Ritz-Carl<strong>to</strong>n<br />
Hotel, Bos<strong>to</strong>n. Arnold Miller, MD, course direc<strong>to</strong>r.<br />
Inquiries: Department of Continuing Medical Education,<br />
Harvard Medical School, PO Box 825, Bos<strong>to</strong>n,<br />
MA 02117. Tel 617-432-1525.<br />
Dec 7-9: 25th Annual New York Cardiovascular Symposium.<br />
New York Hil<strong>to</strong>n and Towers, New York.<br />
Inquiries: <strong>American</strong> College of Cardiology, 9111 Old<br />
George<strong>to</strong>wn Rd, Bethesda, MD 20814-1699. Tel<br />
800-257-4739 (outside the US and Canada, 301-897-<br />
2695.) Fax 301-897-9745.<br />
Dec 7-10: Neurosurgery NYC/1992. Grand Hyatt New<br />
York. Inquiries: NYU Medical Center, Post-Graduate<br />
Medical School, 550 First Ave, New York, NY<br />
10016. Tel 212-263-5295.<br />
Dec 8-9: Transesophageal Echocardiography Course. St.<br />
Louis University Medical Center, St. Louis, Mo.<br />
Sponsored by the St. Louis University Medical Center.<br />
Inquiries: Continuing Medical Education,<br />
School of Medicine, 1402 South Grand, Room 259,<br />
St. Louis, MO 63104. Tel 314-577-8167. Fax 314-<br />
577-8214.<br />
Dec 9: Multidisciplinary Approach <strong>to</strong> the Fetus and Neonate<br />
With Congenital Anomalies. Long Island Campus<br />
for the Albert Einstein College of Medicine.<br />
Frederick Z. Bierman, MD, and Adiel Fleischer,<br />
MD, program chairmen. Inquiries: June Lewis, Office<br />
of Continuing Education, Long Island Jewish<br />
Medical Center, New Hyde Park, NY 11042. Tel<br />
718-470-8650. Fax 516-352-4801.<br />
Dec 9-11: Cardiac Auscultation for Physician Assistants,<br />
Nurse Practitioners, and Cardiac Nurses. Bethesda,<br />
Md. James A. Ronan Jr, MD, direc<strong>to</strong>r. Inquiries:<br />
<strong>American</strong> College of Cardiology, Heart House<br />
Learning Center, 9111 Old George<strong>to</strong>wn Rd, Bethesda,<br />
MD 20814-1699. Tel 800-257-4737 or 301-<br />
897-2653. Fax 301-897-9745.<br />
Dec 11-13: The 10th Annual Advances in Heart Disease.<br />
San Francisco. Inquiries: <strong>American</strong> College of Cardiology,<br />
Extramural Programs Department, 9111<br />
Old George<strong>to</strong>wn Rd, Bethesda, MD 20814-1699. Tel<br />
800-257-4739 or 301-897-2695. Fax 301-897-9745.<br />
Dec 14-16: The Role of Echocardiography/Doppler in<br />
Clinical Decision Making-VI. Bethesda, Md. Anthony<br />
N. DeMaria, MD, and Mikel D. Smith, MD,<br />
direc<strong>to</strong>rs. Inquiries: <strong>American</strong> College of Cardiology,<br />
Heart House Learning Center, 9111 Old<br />
Meetings Calendar<br />
A1568<br />
George<strong>to</strong>wn Rd, Bethesda, MD 20814-1699. Tel<br />
800-257-4737 or 301-897-2653. Fax 301-897-9745.<br />
Dec 14-19: 11th Annual CT/MRI Head <strong>to</strong> Toe. Grand<br />
Hyatt, New York. Inquiries: New York University,<br />
550 First Ave, New York, NY 10016. Tel 212-263-<br />
5295.<br />
Dec 27-30: Clinical Cardiology 1992: Seventh Annual<br />
Symposium. Marriott World Center, Orlando, Fla.<br />
Sponsored by the University of Wisconsin, Continuing<br />
Medical Education, and Sinai-Samaritan Medical<br />
Center. Inquiries: Sarah Aslakson, Continuing<br />
Medical Education, 2715 Marshall Ct, Madison, WI<br />
53705. Tel 608-263-2856.<br />
Dec 28-Jan 2: Year-End Review of Imaging and Intervention.<br />
Intercontinental Hotel, Maui, Hawaii. Sponsored<br />
by the University of California, San Diego.<br />
David S. Feigin, MD, program direc<strong>to</strong>r. Inquiries:<br />
Dawne Ryals, Ryals and Associates, PO Box 1925,<br />
Roswell, GA 30077-1925. Tel 404-641-9773. Fax<br />
404-552-9859.<br />
1993<br />
Jan 4-8: The Complete Magnetic Resonance Imaging<br />
Course. Ritz-Carl<strong>to</strong>n, Kapalua, Maui, Hawaii. Sponsored<br />
by the Hospital of the University of Pennsylvania.<br />
David Yousem, MD, course direc<strong>to</strong>r. Inquiries:<br />
Janice Ford, Manager, CME, Department of<br />
Radiology, Hospital of the University of Pennsylvania,<br />
3400 Spruce St, Philadelphia, PA 19104. Tel<br />
215-662-6904 or 215-662-6982. Fax 215-349-5925.<br />
Jan 11-15: 24th Annual Cardiovascular Conference at<br />
Snowmass. Snowmass, Colo. John H.K. Vogel, MD,<br />
and Bruce C. Pa<strong>to</strong>n, MD, direc<strong>to</strong>rs. Inquiries: <strong>American</strong><br />
College of Cardiology, Extramural Programs<br />
Department, 9111 Old George<strong>to</strong>wn Rd, Bethesda,<br />
MD 20814-1699. Tel 800-257-4739 or 301-897-2695.<br />
Fax 301-897-9745.<br />
Jan 11-16: Specialty Review in Thoracic Surgery. Holiday<br />
Inn Chicago City Centre, Chicago. Sponsored by the<br />
National Center for Advanced Medical Education.<br />
Sidney Levitsky, MD, and Robert W. Anderson,<br />
MD, coordina<strong>to</strong>rs. Inquiries: Registration Office,<br />
707 S Wood St, Chicago, IL 60612. Tel 1-800-621-<br />
4651.<br />
Jan 14-16: Pediatric Electrocardiography, Electrophysiology,<br />
and Pacing. Bethesda, Md. Paul C. Gillette,<br />
MD, and Arthur Garson Jr, MD, direc<strong>to</strong>rs. Inquiries:<br />
<strong>American</strong> College of Cardiology, Heart House<br />
Learning Center, 9111 Old George<strong>to</strong>wn Rd, Bethesda,<br />
MD 20814-1699. Tel 800-257-4737 or 301-<br />
897-2653. Fax 301-897-9745.<br />
Jan 16-17: Interventional Radiology Update. Ritz-Carl<strong>to</strong>n<br />
Resort Hotel, Laguna Niguel, Calif. Sponsored by<br />
Stanford University Medical Center. Gary M.<br />
Glazer, MD, program chairman; Michael Dake, MD,<br />
program direc<strong>to</strong>r. Inquiries: Dawne Ryals, Ryals and<br />
Associates, PO Box 1925, Roswell, GA 30077-1925.<br />
Tel 404-641-9773. Fax 404-552-9859.<br />
Jan 18-20: Neuroradiology Update. Ritz-Carl<strong>to</strong>n Resort<br />
Hotel, Laguna Niguel, Calif. Sponsored by Stanford<br />
University Medical Center. Gary M. Glazer, MD,
program chairman. Bar<strong>to</strong>n Lane, MD, program direc<strong>to</strong>r.<br />
Inquiries: Dawne Ryals, Ryals and Associates,<br />
PO Box 1925, Roswell, GA 30077-1925. Tel<br />
404-641-9773. Fax 404-552-9859.<br />
Jan 21-22: Advances in Cardiac Diagnosis and Treatment.<br />
Shera<strong>to</strong>n Baltimore North, Towson, Md. Sponsored<br />
by The Johns Hopkins University School of Medicine.<br />
Inquiries: Program Coordina<strong>to</strong>r, Johns Hopkins<br />
Medical Institutions, Office of Continuing Education,<br />
Turner Building, 720 Rutland Ave,<br />
Baltimore, MD 21205. Tel 410-955-2959.<br />
Jan 21-23: Cases in Echocardiography: TEE, Doppler, and<br />
Stress-Interpretation and Clinical Decision Making.<br />
Bethesda, Md. Rick A. Nishimura, MD, and<br />
Fletcher A. Miller Jr, MD, direc<strong>to</strong>rs. Inquiries:<br />
<strong>American</strong> College of Cardiology, Heart House<br />
Learning Center, 9111 Old George<strong>to</strong>wn Rd, Bethesda,<br />
MD 20814-1699. Tel 800-257-4737 or 301-<br />
897-2653. Fax 301-897-9745.<br />
Jan 21-23: Clinical Nuclear Cardiology: Case Review With<br />
the Experts. Los Angeles. Daniel S. Berman, MD,<br />
and Jamshid Maddahi, MD, direc<strong>to</strong>rs. Inquiries:<br />
<strong>American</strong> College of Cardiology, Extramural Programs,<br />
9111 Old George<strong>to</strong>wn Rd, Bethesda, MD<br />
20814-1699. Tel 800-257-4739 (outside US and Canada,<br />
301-897-2695). Fax 301-897-9745.<br />
Jan 24-26: Adults With Congenital Heart Disease. San<br />
Diego, Calif. David J. Sahn, MD, Samuel Kaplan,<br />
MD, and Ralph Shabeti, MD, direc<strong>to</strong>rs. Inquiries:<br />
<strong>American</strong> College of Cardiology, Extramural Programs,<br />
9111 Old George<strong>to</strong>wn Rd, Bethesda, MD<br />
20814-1699. Tel 800-257-4739 (outside US and Canada,<br />
301-897-2695). Fax 301-897-9745.<br />
Jan 27-29: Interventional Cardiology: Update for Nurses<br />
and Technologists in Cardiac Catheterization Labora<strong>to</strong>ries.<br />
Bethesda, Md. Kenneth M. Kent, MD,<br />
PhD, direc<strong>to</strong>r. Inquiries: <strong>American</strong> College of Cardiology,<br />
Heart House Learning Center, 9111 Old<br />
George<strong>to</strong>wn Rd, Bethesda, MD 20814-1699. Tel<br />
800-257-4737 or 301-897-2653. Fax 301-897-9745.<br />
Jan 27-31: International Congress VI: Endovascular Interventions-Tomorrow's<br />
Technology Today. Sponsored<br />
by the Arizona Heart Institute and Foundation.<br />
Inquiries: Erika Scott, International Congress<br />
VI, 2632 N 20th St, Phoenix, AZ 85006. Tel 602-266-<br />
2200. Fax 602-240-6160.<br />
Jan 29-31: The 12th Annual Perspectives on New Diagnostic<br />
and Therapeutic Techniques in Clinical Cardiology.<br />
Walt Disney World, Fla. C. Richard Conti, MD,<br />
direc<strong>to</strong>r. Inquiries: <strong>American</strong> College of Cardiology,<br />
Extramural Programs, 9111 Old George<strong>to</strong>wn Rd,<br />
Bethesda, MD 20814-1699. Tel 800-257-4739 (outside<br />
US and Canada, 301-897-2695). Fax 301-897-<br />
9745.<br />
Feb 1-3: Cardiovascular Conference at Snowshoe. Snowshoe,<br />
W.V. William H. Carter, MD, direc<strong>to</strong>r. Inquiries:<br />
<strong>American</strong> College of Cardiology, Extramural<br />
Programs, 9111 Old George<strong>to</strong>wn Rd, Bethesda, MD<br />
20814-1699. Tel 800-257-4739 (outside US and Canada,<br />
301-897-2695). Fax 301-897-9745.<br />
Feb 1-5: Echo Hawaii 1993. Maui, Hawaii. A. Jamil Tajik,<br />
MD, and James B. Seward, MD, direc<strong>to</strong>rs. Inquiries:<br />
Meetings Calendar<br />
A1569<br />
<strong>American</strong> College of Cardiology, Extramural Programs,<br />
9111 Old George<strong>to</strong>wn Rd, Bethesda, MD<br />
20814-1699. Tel 800-257-4739 (outside US and Canada,<br />
301-897-2695). Fax 301-897-9745.<br />
Feb 2-6: 16th Annual Meeting of the <strong>American</strong> Society of<br />
Neuroimaging. Walt Disney World Village, Orlando,<br />
Fla. Inquiries: Linda Wilkerson, Administra<strong>to</strong>r,<br />
<strong>American</strong> Society of Neuroimaging, 2221 University<br />
Avenue SE, Suite 340, Minneapolis, MN 55414. Tel<br />
612-378-7240. Fax 612-623-3504.<br />
Feb 6-10: Seventh International Symposium on Cerebral<br />
Hemodynamics: Transcranial Doppler, Cerebral<br />
Blood Flow, and Other Modalities. Hil<strong>to</strong>n at Walt<br />
Disney World Village, Lake Buena Vista, Fla. Inquiries:<br />
Julie A. Hauf, Conference Coordina<strong>to</strong>r, Institute<br />
of Applied Physiology and Medicine, 701 16th<br />
Ave, Seattle, WA 98122. Tel 206-553-7330. Fax<br />
206-553-1717.<br />
Feb 8-12: Current Topics in Diagnostic Imaging. Hyatt<br />
Regency Cerromar Beach, Puer<strong>to</strong> Rico. Inquiries:<br />
New York University, 550 First Ave, New York, NY<br />
10016. Tel 212-263-5295.<br />
Feb 8-12: Eighth Annual Cardiovascular Conference at<br />
Hawaii. Kohala Coast, Hawaii. John H.K. Vogel,<br />
MD, direc<strong>to</strong>r. Inquiries: <strong>American</strong> College of Cardiology,<br />
Extramural Programs, 9111 Old George<strong>to</strong>wn<br />
Rd, Bethesda, MD 20814-1699. Tel 800-257-4739<br />
(outside US and Canada, 301-897-2695). Fax 301-<br />
897-9745.<br />
Feb 8-12: 1993 Gordon <strong>Research</strong> Conference on Angiotensin.<br />
Casa Sirena Resort, Oxnard, Calif. Inquiries:<br />
William F. Ganong, MD, Department of Physiology,<br />
University of California, San Francisco, CA 94143-<br />
0444. Tel 415-476-1869. Fax 415-476-4929.<br />
Feb 9-13: Cardiovascular Conference at Snowbird. Snowbird,<br />
Utah. Jeffrey L. Anderson, MD, and Arthur D.<br />
Hagan, MD, direc<strong>to</strong>rs. Inquiries: <strong>American</strong> College<br />
of Cardiology, Extramural Programs, 9111 Old<br />
George<strong>to</strong>wn Rd, Bethesda, MD 20814-1699. Tel<br />
800-257-4739 (outside US and Canada, 301-897-<br />
2695). Fax 301-897-9745.<br />
Feb 11-13: 18th International Joint Conference on Stroke<br />
" and Cerebral <strong>Circulation</strong>. Fontainebleu Hotel, Miami<br />
Beach, Fla. Sponsored by the AHA's Stroke<br />
Council. David G. Sherman, MD, program chairman.<br />
Inquiries: <strong>American</strong> Heart Association, Scientific<br />
and Corporate Meetings, 7272 Greenville Ave,<br />
Dallas, TX 75231-4596. Tel 214-706-1511. Fax 214-<br />
373-3406.<br />
Feb 14-18: Third International Conference on Endothelin.<br />
Hous<strong>to</strong>n, Tex. Inquiries: Dr P.M. Vanhoutte, Baylor<br />
College of Medicine, Center for Experimental Therapeutics,<br />
One Baylor Plaza, Room 802E, Hous<strong>to</strong>n,<br />
TX 77030. Tel 713-798-6453. Fax 713-799-2469.<br />
Feb 15-19: Diagnostic Imaging Update: Mammography,<br />
Magnetic Resonance Imaging, Body Imaging, Neuroradiology,<br />
Pediatrics. Ritz-Carl<strong>to</strong>n Resort Hotel,<br />
Palm Beach, Fla. Gary M. Glazer, MD, program<br />
chairman; R. Brooke Jeffrey Jr, MD, program direc<strong>to</strong>r.<br />
Inquiries: Dawne Ryals, Ryals and Associates,<br />
PO Box 1925, Roswell, GA 30077-1925. Tel 404-641-<br />
9773. Fax 404-552-9859.
Feb 20-23: State-of-the-Art Echocardiography. Tucson,<br />
Ariz. A. Jamil Tajik, MD, and James B. Seward, MD,<br />
direc<strong>to</strong>rs. Inquiries: <strong>American</strong> College of Cardiology,<br />
Extramural Programs, 9111 Old George<strong>to</strong>wn<br />
Rd, Bethesda, MD 20814-1699. Tel 800-257-4739<br />
(outside US and Canada, 301-897-2695). Fax 301-<br />
897-9745.<br />
Feb 21: Phlebology Review. Hil<strong>to</strong>n at Walt Disney World<br />
Village, Lake Buena Vista, Fla. Inquiries: North<br />
<strong>American</strong> Society of Phlebology, 511 Encinitas Blvd,<br />
Suite 111, Encinitas, CA 92024. Tel 619-632-5990.<br />
Fax 619-632-5999.<br />
Feb 22-24: Sixth Annual Congress of the North <strong>American</strong><br />
Society of Phlebology on the Advances in Sclerotherapy<br />
and the Advances in Surgical and Medical<br />
Treatment of Venous Disease. Hil<strong>to</strong>n at Walt Disney<br />
World Village, Lake Buena Vista, Fla. Inquiries:<br />
North <strong>American</strong> Society of Phlebology, 511 Encinitas<br />
Blvd, Suite 111, Encinitas, CA 92024. Tel 619-<br />
632-5990. Fax 619-632-5999.<br />
Feb 22-24: Cardiopulmonary Rehabilitation: Status '93.<br />
Shera<strong>to</strong>n World Hotel, Orlando, Fla. Inquiries:<br />
Michael L. Pollock, PhD, University of Florida,<br />
Center for Exercise Science, Florida Gymnasium,<br />
Room 27, Gainesville, FL 32611. Tel 904-392-9575.<br />
Fax 904-392-0316.<br />
Feb 22-26: Diagnostic Imaging Update. Ritz Carl<strong>to</strong>n Resort<br />
Hotel, Kapalua Bay, Hawaii. Sponsored by<br />
Stanford University Medical Center. Gary M.<br />
Glazer, MD, program chairman; R. Brooke Jeffrey<br />
Jr., MD, program direc<strong>to</strong>r. Inquiries: Dawne Ryals,<br />
Ryals and Associates, PO Box 1925, Roswell, GA<br />
30077-1925. Tel 404-641-9773. Fax 404-552-9859.<br />
Feb 22-26: Magnetic Resonance Imaging. Ritz-Carl<strong>to</strong>n<br />
Hotel, Naples, Fla. Sponsored by the University of<br />
Toron<strong>to</strong>. David 0. Davis, MD; Edward Kassell,<br />
DDS, MD; and Walter Kucharczyk, MD, program<br />
direc<strong>to</strong>rs. Inquiries: Dawne Ryals, Ryals and Associates,<br />
PO Box 1925, Roswell, GA 30077-1925. Tel<br />
404-641-9773. Fax 404-552-9859.<br />
Feb 26-28: Fifth Annual Advances in Diagnostic and<br />
Therapeutic Cardiac Catheterization. Lake Buena<br />
Vista, Fla. Carl J. Pepine, MD, direc<strong>to</strong>r. Inquiries:<br />
<strong>American</strong> College of Cardiology, Extramural Programs,<br />
9111 Old George<strong>to</strong>wn Rd, Bethesda, MD<br />
20814-1699. Tel 800-257-4739 (outside US and Canada,<br />
301-897-2695). Fax 301-897-9745.<br />
Feb 27: Preventive Cardiology Forum III. University of<br />
Texas Medical School at Hous<strong>to</strong>n. Inquiries: Ruby<br />
Benjamin-Garner, The University of Texas Health<br />
Science Center at Hous<strong>to</strong>n, 6431 Fannin, Texas<br />
Medical Center, PO Box 20708, Hous<strong>to</strong>n, TX 77225.<br />
Tel 713-792-5178.<br />
Feb 27-Mar 4: 18th Annual Meeting of the Society of<br />
Cardiovascular and Interventional Radiology. New<br />
Orleans Convention Center, New Orleans, La. Robert<br />
Rosen, MD, program chairman; Gary Becker,<br />
MD, scientific chairman. Inquiries: SCVIR, 10201<br />
Lee Highway, Suite 160, Fairfax, VA 22030. Tel<br />
703-691-1805. Fax 703-691-1855.<br />
Feb 28-Mar 2: Positron Emission Tomography: Clinical<br />
Applications and Practical Considerations. Dana<br />
Meetings Calendar<br />
I<br />
A1570<br />
Point Resort, Dana Point, Calif. Inquiries: Wendy<br />
Hagar, Labora<strong>to</strong>ry of Nuclear Medicine, UCLA<br />
School of Medicine, 10833 Le Conte Ave, Los Angeles,<br />
CA 90024-1721. Tel 310-825-2724. Fax 310-<br />
825-4517.<br />
Feb 28-Mar 3: Third Biennial Team Approach <strong>to</strong> Pediatric<br />
Heart Disease. Westin Hotel, Vail, Colo. Sponsored<br />
by The Children's Hospital and University of Colorado<br />
School of Medicine affiliated programs. Robert<br />
R. Wolfe, MD, and David R. Clarke, MD, program<br />
cochairmen. Inquiries: Conferences Department,<br />
The Children's Hospital, 1056 E 19th Ave, Denver,<br />
CO 80218-1088. Tel 303-861-6946. Fax 303-837-<br />
2595.<br />
Feb 28-Mar 5: Seventh Annual Cardiology for the Clinician:<br />
Practical Guidelines for Merging Advances in<br />
Cardiology With Bedside Medicine. Snowmass, Colo.<br />
Inquiries: Sue Talbert, University of Illinois at Chicago<br />
Conferences and Institutes (M/C 607), Box<br />
6998, Chicago, IL 60680. Tel 312-996-4631. Fax<br />
312-996-5227.<br />
Mar 8-12: Eighth Annual San Diego Postgraduate Magnetic<br />
Resonance Imaging Course. Hotel Del Coronado,<br />
San Diego, Calif. Sponsored by the University<br />
of California, San Diego, School of Medicine. John<br />
R. Hesselink, MD, program direc<strong>to</strong>r. Inquiries:<br />
Dawne Ryals, Ryals and Associates, PO Box 1925,<br />
Roswell, GA 30077-1925. Tel 404-641-9773. Fax<br />
404-552-9859.<br />
Mar 11-13: Third Annual Symposium on Coronary Stenting:<br />
A Live Demonstration Course. Shera<strong>to</strong>n Grande<br />
Torrey Pines Hotel, La Jolla, Calif. Inquiries: Department<br />
of Academic Affairs, 403C, Scripps Clinic<br />
and <strong>Research</strong> Foundation, 10666 N Torrey Pines<br />
Road, La Jolla, CA 92037. Tel 619-554-8556. Fax<br />
619-554-6310.<br />
Mar 12-14: R Adams Cowley 15th National Trauma<br />
Symposium. Hyatt Regency Baltimore, Baltimore,<br />
Md. Inquiries: Office of International Development,<br />
MIEMSS, 410 W Lombard St, Suite 416,<br />
Baltimore, MD 21201. Tel 410-328-2399. Fax 410-<br />
328-0501.<br />
Mar 14-17: Seventh Annual Magnetic Resonance Imaging<br />
Conference. Arizona Biltmore Resort Hotel, Phoenix,<br />
Ariz. Sponsored by the Barrow Neurological<br />
Institute of St. Joseph's Hospital and Medical Center.<br />
Bur<strong>to</strong>n P. Drayer, MD, and John A. Hodak, MD,<br />
course direc<strong>to</strong>rs. Inquiries: Maria Sodaro, RN, BSN,<br />
<strong>Research</strong> and Education Coordina<strong>to</strong>r, Radiologic<br />
Education Center, St. Joseph's Hospital and Medical<br />
Center, 350 W Thomas Rd, Phoenix, AZ 85013. Tel<br />
602-285-3956.<br />
Mar 14-18: 42nd Annual Scientific Session of the <strong>American</strong><br />
College of Cardiology. Anaheim, Calif. Inquiries:<br />
Meeting Services Department, <strong>American</strong> College of<br />
Cardiology, 9111 Old George<strong>to</strong>wn Rd, Bethesda,<br />
MD 20814. Tel 800-253-4636 or 301-897-5400.<br />
Mar 14-18: Annual Meeting and Course: Society of Thoracic<br />
Radiology. Ritz-Carl<strong>to</strong>n Resort Hotel, Amelia<br />
Island, Fla. Richard Webb, MD, president; Robert<br />
Pugatch, MD, program direc<strong>to</strong>r. Inquiries: Dawne<br />
Ryals, Ryals and Associates, PO Box 1925, Roswell,
GA 30077-1925. Tel 404-641-9773. Fax 404-552-<br />
9859.<br />
Mar 15-18: 37th Annual Convention of the <strong>American</strong><br />
Institute of Ultrasound in Medicine. Honolulu, Hawaii.<br />
Inquiries: AIUM Convention Department,<br />
11200 Rockville Pike, Suite 205, Rockville, MD<br />
20852-3139. Tel 301-881-2486. Fax 301-881-7303.<br />
Mar 17-20: 33rd Annual Conference on Cardiovascular<br />
Disease Epidemiology. Sweeney Convention Center,<br />
Santa Fe, N.M. Sponsored by the AHA's Council on<br />
Epidemiology and Prevention. Stephen P. Fortmann,<br />
MD, program committee chairman. Inquiries:<br />
<strong>American</strong> Heart Association, Scientific and Corporate<br />
Meetings, 7272 Greenville Ave, Dallas, TX<br />
75231-4596. Tel 214-706-1511. Fax 214-373-3406.<br />
Mar 22-25: The Frohlich Award Conference-Doing More<br />
Good Than Harm: The Evaluation of Interventions.<br />
Grand Hyatt, New York. Kenneth S. Warren, MD,<br />
and Frederick Mosteller, MD, conference chairmen.<br />
Inquiries: Conference Department, The New York<br />
Academy of Sciences, 2 East 63rd St, New York, NY<br />
10021. Tel 212-838-0230. Fax 212-838-5640.<br />
Mar 29-Apr 2: Advanced Seminars in Diagnostic Imaging.<br />
Willard Intercontinental, Washing<strong>to</strong>n, D.C. Sponsored<br />
by the University of California, San Diego.<br />
David S. Feigin, MD, program direc<strong>to</strong>r. Inquiries:<br />
Dawne Ryals, Ryals and Associates, PO Box 1925,<br />
Roswell, GA 30077-1925. Tel 404-641-9773. Fax<br />
404-552-9859.<br />
Mar 29-Apr 2: 1993 Magnetic Resonance Imaging Update<br />
at Vail: Brain, Spine, Head and Neck, and Musculoskeletal.<br />
The Westin Hotel, Vail, Colo. Sponsored<br />
by the Hospital of the University of Pennsylvania. Dr<br />
Herbert Goldberg, course direc<strong>to</strong>r. Inquiries: Janice<br />
Ford, Manager, CME, Department of Radiology,<br />
Hospital of the University of Pennsylvania, 3400<br />
Spruce St, Philadelphia, PA 19104. Tel 215-662-<br />
6904 or 215-662-6982. Fax 215-349-5925.<br />
Apr 2-3: International Conference on High Density Lipoprotein<br />
Cholesterol and Triglycerides: Role in Coronary<br />
Heart Disease and Labora<strong>to</strong>ry Measurement.<br />
Washing<strong>to</strong>n, DC. Sponsored by the George<strong>to</strong>wn<br />
University Medical Center and the Lorenzini Foundation,<br />
Milan, Italy. Inquiries: Dr Ajit Sanghvi,<br />
George<strong>to</strong>wn University Hospital, 3800 Reservoir<br />
Road, NW, Washing<strong>to</strong>n, DC 20007-2197. Tel 202-<br />
784-3011. Fax 202-784-2316.<br />
Apr 12-15: Immunosuppressive and Anti-inflamma<strong>to</strong>ry<br />
Drugs. Orlando Marriott International, Orlando,<br />
Fla. Sponsored by the New York Academy of Sciences.<br />
Abstracts by Jan 7, 1993. Inquiries: Conference<br />
Department, New York Academy of Sciences, 2<br />
East 63rd St, New York, NY 10021. Tel 212-838-<br />
0230. Fax 212-888-2894.<br />
Apr 15-17: 34th National Student <strong>Research</strong> Forum.<br />
Galves<strong>to</strong>n, Tex. Inquiries: National Student <strong>Research</strong><br />
Forum, Room G-210 Ashbel Smith Building,<br />
Route M-17, The University of Texas Medical<br />
Branch, Galves<strong>to</strong>n, TX 77550. Tel 409-772-3762.<br />
Apr 22-23: Obesity and Coronary Artery Disease. Wash-<br />
- ing<strong>to</strong>n, DC. Sponsored by the AHA's Council on<br />
_ Arteriosclerosis and the Nutrition Committee. Inquiries:<br />
<strong>American</strong> Heart Association, Scientific and<br />
Meetings Calendar<br />
A1571<br />
Corporate Meetings, 7272 Greenville Ave, Dallas,<br />
TX 75231-4596. Tel 214-706-1511. Fax 214-373-<br />
3406.<br />
Apr 22-24: Cardiology Fiesta in San An<strong>to</strong>nio: Update on<br />
Cardiac Diagnostic and Therapeutic Techniques.<br />
San An<strong>to</strong>nio, Tex. Steven R. Bailey, MD, and Miguel<br />
Zabalgoitia, MD, direc<strong>to</strong>rs. Inquiries: <strong>American</strong> College<br />
of Cardiology, Extramural Programs, 9111 Old<br />
George<strong>to</strong>wn Rd, Bethesda, MD 20814-1699. Tel<br />
800-257-4739 (outside US and Canada, 301-897-<br />
2695). Fax 301-897-9745.<br />
Apr 25-29: 10th Scientific Meeting of the Inter-<strong>American</strong><br />
Society of Hypertension. La Jolla, Calif. Inquiries:<br />
Mor<strong>to</strong>n P. Printz, PhD, Department of Pharmacology,<br />
0636, University of California, San Diego, La<br />
Jolla, CA 92093-0636. Tel 619-534-1368. Fax 619-<br />
534-0464.<br />
May 6-8: 14th Annual Scientific Session of the North<br />
<strong>American</strong> Society of Pacing and Electrophysiology.<br />
San Diego, Calif. Inquiries: NASPE, 377 Elliot St,<br />
New<strong>to</strong>n Upper Falls, MA 02164. Tel 617-244-7300.<br />
Fax 617-244-3920.<br />
May 8-12: AAMI 28th Annual Meeting and Exposition.<br />
Bos<strong>to</strong>n, Mass. Inquiries: Association for the Advancement<br />
of Medical Instrumentation, 3330 Washing<strong>to</strong>n<br />
Blvd, Suite 400, Arling<strong>to</strong>n, VA 22201-4598.<br />
Tel 703-525-4890.<br />
May 11-14: Consultant's Course in Cardiology. New York,<br />
NY. Louis E. Teichholz, MD, Richard Gorlin, MD,<br />
and Simon Dack, MD, direc<strong>to</strong>rs. Inquiries: <strong>American</strong><br />
College of Cardiology, Extramural Programs,<br />
9111 Old George<strong>to</strong>wn Rd, Bethesda, MD 20814-<br />
1699. Tel 800-257-4739 (outside US and Canada,<br />
301-897-2695). Fax 301-897-9745.<br />
May 12-14: Clinical Auscultation of the Heart. Washing<strong>to</strong>n,<br />
D.C. W. Proc<strong>to</strong>r Harvey, MD, James A. Ronan<br />
Jr, MD, and John F. Staple<strong>to</strong>n, MD, direc<strong>to</strong>rs.<br />
Inquiries: <strong>American</strong> College of Cardiology, Extramural<br />
Programs, 9111 Old George<strong>to</strong>wn Rd, Bethesda,<br />
MD 20814-1699. Tel 800-257-4739 (outside<br />
US and Canada, 301-897-2695). Fax 301-897-9745.<br />
May 20-21: Human Subject Protections Workshop. Anchorage,<br />
Alaska. Sponsored by the University of<br />
Alaska, Anchorage, and Northwest Indian College.<br />
Inquiries: Ms. Darlene Marie Ross, Executive Assistant<br />
for Education, Division of Human Subject Protection,<br />
Office for Protection From <strong>Research</strong> Risks,<br />
National Institutes of Health, 9000 Rockville Pike,<br />
Building 31, Room 5B59, Bethesda, MD 20892. Tel<br />
301-496-8101.<br />
May 20-22: Sixth Annual Trauma Anesthesia and Critical<br />
Care Symposium. Hyatt Regency Baltimore, Baltimore,<br />
Md. Inquiries: Office of International Development,<br />
410 West Lombard St, Suite 416, Baltimore,<br />
MD 21201. Tel 410-328-2399. Fax 410-328-0501.<br />
May 26-29: 17th Annual Update: Cardiology for the Primary<br />
Physician During Spole<strong>to</strong> Festival. Charles<strong>to</strong>n,<br />
S.C. Peter C. Gazes, MD, and James F. Spann Jr,<br />
MD, direc<strong>to</strong>rs. Inquiries: <strong>American</strong> College of Cardiology,<br />
Extramural Programs, 9111 Old George<strong>to</strong>wn<br />
Rd, Bethesda, MD 20814-1699. Tel 800-257-
4739 (outside US and Canada, 301-897-2695). Fax<br />
301-897-9745.<br />
June 2-5: Advanced Echocardiography and Doppler Ultrasound<br />
1993. San Diego, Calif. Pravin M. Shah, MD,<br />
direc<strong>to</strong>r. Inquiries: <strong>American</strong> College of Cardiology,<br />
Extramural Programs, 9111 Old George<strong>to</strong>wn Rd,<br />
Bethesda, MD 20814-1699. Tel 800-257-4739 (outside<br />
US and Canada, 301-897-2695). Fax 301-897-<br />
9745.<br />
June 9-12: Recent Advances in Cardiovascular Therapeutics.<br />
Bos<strong>to</strong>n. William E. Boden, MD, direc<strong>to</strong>r. Inquiries:<br />
<strong>American</strong> College of Cardiology, Extramural<br />
Programs, 9111 Old George<strong>to</strong>wn Rd, Bethesda, MD<br />
20814-1699. Tel 800-257-4739 (outside US and Canada,<br />
301-897-2695). Fax 301-897-9745.<br />
June 14-18: Magnetic Resonance Imaging: A State-of-the-<br />
Art Clinical Review. Ritz-Carl<strong>to</strong>n Resort Hotel, San<br />
Francisco, Calif. Sponsored by Stanford University<br />
Medical Center. Gary M. Glazer, MD, program<br />
chairman; Robert J. Herfkens, MD; Dieter R. Enzmann,<br />
MD; and Ann G. Bjorkengren, MD, program<br />
direc<strong>to</strong>rs. Inquiries: Dawne Ryals, Ryals and Associates,<br />
PO Box 1925, Roswell, GA 30077-1925. Tel<br />
404-641-9773. Fax 404-552-9859.<br />
July 6-9: Third International Meeting on Platelets and<br />
Vascular Occlusion. Hil<strong>to</strong>n of Santa Fe and Eldorado<br />
Hotel, Santa Fe, N.M. Sponsored by the New<br />
York Academy of Sciences. Abstracts by Mar 30,<br />
1993 (send <strong>to</strong> Garret A. FitzGerald, MD, Center for<br />
Cardiovascular Science, Department of Medicine<br />
and Experimental Therapeutics, University College<br />
Dublin, Mater Hospital, 41 Eccles St, Dublin 6,<br />
Ireland). Inquiries: Conference Department, New<br />
York Academy of Sciences, 2 East 63rd St, New<br />
York, NY 10021. Tel 212-838-0230. Fax 212-888-<br />
2894.<br />
July 15-16: Human Subject Protections Workshop. Minneapolis,<br />
Minn. Sponsored by the University of Minnesota<br />
of Minneapolis-St. Paul and the <strong>American</strong><br />
Indian Health Care Association. Inquiries: Ms. Darlene<br />
Marie Ross, Executive Assistant for Education,<br />
Division of Human Subject Protection, Office for<br />
Protection From <strong>Research</strong> Risks, National Institutes<br />
of Health, 9000 Rockville Pike, Building 31, Room<br />
5B59, Bethesda, MD 20892. Tel 301-496-8101.<br />
Aug 4-8: Molecular Biology of the Normal, Hypertrophied,<br />
and Failing Heart. Asilomar Conference Center,<br />
Pacific Grove, Calif. Sponsored by the AHA's Councils<br />
on Basic Science, Clinical Cardiology, <strong>Circulation</strong>,<br />
and High Blood Pressure <strong>Research</strong>. Kenneth R.<br />
Chien, MD, PhD, and Richard A. Walsh, MD,<br />
program chairmen. Inquiries: <strong>American</strong> Heart Association,<br />
Scientific and Corporate Meetings, 7272<br />
Greenville Ave, Dallas, TX 75231-4596. Tel 214-<br />
706-1511. Fax 214-373-3406.<br />
Sept 28-Oct 1: 47th Annual Fall Conference and Scientific<br />
Sessions of the Council for High Blood Pressure<br />
<strong>Research</strong>. Hyatt Regency, San Francisco. Sponsored<br />
by the AHA's Council for High Blood Pressure<br />
<strong>Research</strong>. Inquiries: <strong>American</strong> Heart Association,<br />
Scientific and Corporate Meetings, 7272 Greenville<br />
Meetings Calendar<br />
A1572<br />
Ave, Dallas, TX 75231-4596. Tel 214-706-1511. Fax<br />
214-373-3406.<br />
Sept 30: <strong>American</strong> Board of Internal Medicine 1993 Certification<br />
Examination for Added Qualifications in<br />
Sports Medicine. Registration period: Sept 1, 1992-<br />
Jan 15, 1993. Inquiries: Registration Section, <strong>American</strong><br />
Board of Internal Medicine, 3624 Market St,<br />
Philadelphia, PA 19104. Tel 1-800-441-2246 or<br />
1-215-243-1500.<br />
Oct 14-17: Molecular Cellular Biology of the Vascular<br />
Wall. Bos<strong>to</strong>n. Sponsored by the AIA's Councils on<br />
Arteriosclerosis, Basic Science, Cardiopulmonary<br />
and Critical Care, and High Blood Pressure <strong>Research</strong>.<br />
Inquiries: <strong>American</strong> Heart Association, Scientific<br />
and Corporate Meetings, 7272 Greenville<br />
Ave, Dallas, TX 75231-45%. Tel 214-706-1511. Fax<br />
214-373-3406.<br />
Oct 24-28: 21st Annual Meeting: International Society for<br />
Pediatric Neurosurgery. Marriott's Camelback Inn,<br />
Scottsdale, Ariz. Inquiries: Toby L. Anchie, Manager<br />
- BNI Administration, Barrow Neurological Institute,<br />
350 West Thomas Road, Phoenix, AZ 85013-<br />
4496. Tel 602-285-3579 or 1-800-BARROW-1.<br />
Nov 3-4: <strong>American</strong> Board of Internal Medicine 1993<br />
Certification and Recertification Examinations in<br />
Cardiovascular Disease. Registration period: Jan 1,<br />
1993-Apr 1, 1993. Inquiries: Registration Section,<br />
<strong>American</strong> Board of Internal Medicine, 3624 Market<br />
St, Philadelphia, PA 19104. Tel 1-800-441-2246 or<br />
1-215-243-1500.<br />
Nov 8-11: 66th Scientific Sessions of the <strong>American</strong> Heart<br />
Association. Atlanta, Ga. Inquiries: <strong>American</strong> Heart<br />
Association, Scientific and Corporate Meetings, 7272<br />
Greenville Ave, Dallas, TX 75231-4596. Tel 214-<br />
706-1543. Fax 214-373-3406.<br />
Dec 15-18: Application of Magnetic Resonance <strong>to</strong> the<br />
Cardiovascular System. Atlanta, Ga. Sponsored by<br />
the AIA's Councils on Basic Science, Cardiovascular<br />
Radiology, and Clinical Cardiology. Inquiries:<br />
<strong>American</strong> Heart Association, Scientific and Corporate<br />
Meetings, 7272 Greenville Ave, Dallas, TX<br />
75231-4596. Tel 214-706-1511. Fax 214-373-3406.<br />
1994<br />
Feb 17-19: 19th International Joint Conference on Stroke<br />
E and Cerebral <strong>Circulation</strong>. San Diego, Calif. Sponsored<br />
by the AHA's Stroke Council. Inquiries:<br />
<strong>American</strong> Heart Association, Scientific and Corporate<br />
Meetings, 7272 Greenville Ave, Dallas, TX<br />
75231-4596. Tel 214-706-1511. Fax 214-373-3406.<br />
Feb 23-25: Atherosclerosis, Thrombosis, and Prolifera-<br />
E tion. Orlando, Fla. Sponsored by the AHA's Councils<br />
on Arteriosclerosis, Basic Science, and Cardiovascular<br />
Disease in the Young. Inquiries: <strong>American</strong><br />
Heart Association, Scientific and Corporate Meetings,<br />
7272 Greenville Ave, Dallas, TX 75231-4596.<br />
Tel 214-706-1511. Fax 214-373-3406.<br />
Mar 13-17: 43rd Annual Scientific Session of the <strong>American</strong><br />
College of Cardiology. Atlanta, Ga. Inquiries: Meeting<br />
Services Department, <strong>American</strong> College of Car-
diology, 9111 Old George<strong>to</strong>wn Rd, Bethesda, MD<br />
20814. Tel 800-253-4636 or 301-897-5400.<br />
Mar 16-19: 34th Annual Conference on Cardiovascular<br />
Disease Epidemiology. Hyatt Regency Westshore,<br />
Tampa, Fla. Sponsored by the AHA's Council on<br />
Epidemiology and Prevention. Inquiries: <strong>American</strong><br />
Heart Association, Scientific and Corporate Meetings,<br />
7272 Greenville Ave, Dallas, TX 75231-4596.<br />
Tel 214-706-1511. Fax 214-373-3406.<br />
Apr 17-20: Omega-3 Fatty Acids in Nutrition, Vascular<br />
- Biology, and Medicine. Hous<strong>to</strong>n, Tex. Sponsored by<br />
the AHA's Councils on Arteriosclerosis, Basic Science,<br />
and Thrombosis and the Nutrition Committee.<br />
Inquiries: <strong>American</strong> Heart Association, Scientific<br />
and Corporate Meetings, 7272 Greenville Ave, Dallas,<br />
TX 75231-4596. Tel 214-706-1511. Fax 214-373-<br />
3406.<br />
Sept 27-30: 48th Annual Fall Conference and Scientific<br />
Sessions of the Council for High Blood Pressure<br />
<strong>Research</strong>. Palmer House, Chicago. Sponsored by the<br />
AHA's Council for High Blood Pressure <strong>Research</strong>.<br />
Inquiries: <strong>American</strong> Heart Association, Scientific<br />
Meetings Calendar<br />
.~<br />
A1573<br />
and Corporate Meetings, 7272 Greenville Ave, Dallas,<br />
TX 75231-4596. Tel 214-706-1511. Fax 214-373-<br />
3406.<br />
Nov 14-17: 67th Scientific Sessions of the <strong>American</strong> Heart<br />
Association. Dallas, Tex. Inquiries: <strong>American</strong> Heart<br />
Association, Scientific and Corporate Meetings, 7272<br />
Greenville Ave, Dallas, TX 75231-4596. Tel 214-<br />
706-1543. Fax 214-373-3406.<br />
Nov 27-Dec 2: 79th Annual Meeting of the Radiological<br />
Society of North America. McCormick Place, Chicago.<br />
Inquiries: Direc<strong>to</strong>r, Scientific Meetings, Radiological<br />
Society of North America, 2021 Spring Rd,<br />
Suite 600, Oak Brook, IL 60521. Tel 708-571-2670.<br />
Fax 708-571-7837.<br />
1995<br />
Nov 13-16: 68th Scientific Sessions of the <strong>American</strong> Heart<br />
Association. Anaheim, Calif. Inquiries: <strong>American</strong><br />
Heart Association, Scientific and Corporate Meetings,<br />
7272 Greenville Ave, Dallas, TX 75231-4596.<br />
Tel 214-706-1543. Fax 214-373-3406.<br />
Continued on page A1575
A<br />
1 A A 1<br />
1.<br />
a<br />
A11<br />
A a<br />
1- 1<br />
Information may be<br />
obtained through:<br />
<strong>American</strong> Heart<br />
Association<br />
33rd Annual Conference<br />
on Cardiovascular<br />
Disease Epidemiology<br />
Scientific and Corporate<br />
Meetings<br />
7272 Greenville Avenue<br />
Dallas, TX 75231-4596<br />
(214) 706-1511<br />
Fax: (214) 373-3406<br />
<strong>American</strong><br />
Heart<br />
Association<br />
Statement of Ownership,<br />
Management and<br />
C...<strong>Circulation</strong><br />
{Required by 39 U. S. C. 3685J<br />
1 A, Title of Publication| 1B PUBLICATION NO. 2 Date o Filg<br />
CIRCULATION RESEARCH O O iO 9 07 3 3 10101192<br />
3. Frequency of I-su 3A. N.. of 1ssues Published |3B. A-nal Subscription Pric<br />
Monthly 12 $152.00<br />
4. C-pl- Maiiing Add---s o Kno Offic.o1 P. blicationo G,,-.Co y, Caan,y, S a, d ZJP 4 Code (N,, pint,)<br />
<strong>American</strong> Heart Association, 7272 Greenville Ave., Dallas. TX 75231-4596<br />
5. Copiete. M.iiig Addrssof th. H.adquar of Ge,r. Buin... Officso;the Publihsh, (N.o pie,,)<br />
<strong>American</strong> Heart Association. 7272 Greenville Ave., Dallas. TX 75231-45Q6<br />
6. Full N-. .ad Compl.te Mailing Add---. o Publiesv,, Edit,, and Managing Edi<strong>to</strong>r (7it..o MUST NOrT b blk)<br />
Publisher (N- and C - Mai/ing Address)<br />
Edit., evmPri0oas (N-,n an as Ma so,~Ac n ion, 7272 Gr-enAille Ave., Dalla, TX 75231 4596<br />
New England Regional Primate <strong>Research</strong> Center, P. 0. Box 9102,<br />
Stephen F. Vatner, M D. One Pine Hill Sr_ <strong>to</strong>oithborotgh, MA 01772-9102<br />
M.agin,g Edvt,(Nor / .d Ci.elV aliniiig AdOd...)<br />
New England Regional Primate <strong>Research</strong> Center, P. 0. Box 266,<br />
Stacia WeS Di.. Oii Sothborouqh Ma 01772 n102<br />
7. Ow er by a<br />
d address<br />
i.own fo.doo<br />
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rore o- f io. vi.o If by annor - --- nr ofd sf d .o oeS otb'vi .dho -.i iig..v.ii. If byein a parr<br />
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naead address, -ns b, ,.,,d.) (Irem rn4s -wonl,,d )<br />
Fo0I Ntt..<br />
<strong>American</strong> Heart Association<br />
Compbu Mt.Uk. Addre#<br />
7272 Greenville Ave., Dallas, TO 75231-4690<br />
8. K--w Bondhold-rs M-9tgagee, ---d Other Se-urty Holders 0wning or Holding Percen or M-r of Total Amon..t of Bonds, Mortgages or Other<br />
S-cuities (Ifther r oe , sae<br />
Full No- C~o.pAi M.tb.g Addre.<br />
None<br />
F., Completion by Nonprofnt 0rganizatios AuthorizedTo. Moil t Special Rates (DMM SMii 424C12 olyJ<br />
The pur.ose, f...ction.ad...onprfit t otOf this oad th e..i pt ttus fo F puoses--- oa ppone.... (e k.Co.k if)<br />
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(2)<br />
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P-ecdin,g 12 Months<br />
(If chagd.f pubishernus --- c~ ui ao o,f<br />
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(S,, instKio no nree s esd)P..rcding12 Months Published Nearest <strong>to</strong>Filing Date<br />
A T.oti No Cipse (Ni Pre, R-)<br />
B. Paid and/or Requested Circlaion-<br />
1.Sa0les through d...a,r a , stree..t --vnor d cout sls o<br />
4 -092 4. son<br />
2. Mail 5ubscriptio<br />
(Paid arsfXor regn3d) .156 3.327<br />
C. Total Paid . di., Requested Ci-clation<br />
(SOo if 0B00 ian IOB2) 3 .156 3,327<br />
D. F-e Di.tributi-r by Mail, C-tier or Other M....<br />
Samples, Cpli-teio..ny, ad Oth., FeCo.pies, 288 295<br />
E. Total Distribution (S-n of C and D)<br />
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F Copis. Not Distribut.d<br />
1. Offi, -s, lett .ov una nted, spoiled ftte peintiig 648 878<br />
2. Return, fronn N... Agen,ts<br />
9<strong>American</strong> HeartAssociation<br />
ad. ept ad]. highly skilled, expert; e.g.,<br />
someone with the marketing savvy <strong>to</strong><br />
advertise in <strong>American</strong> Heart Association<br />
journals.<br />
If you need <strong>to</strong> announce:<br />
* recruitment positions,<br />
* meetings, or<br />
* fellowship programs,<br />
consider advertising in an official journal of the<br />
<strong>American</strong> Heart Association. Our rates are<br />
reasonable, and our readership of medical<br />
professionals may be your ideal target market.<br />
Ad copy may be submitted camera-ready, or we<br />
can typeset it. For more information about rates,<br />
deadlines, etc., do the smart thing and contact<br />
us <strong>to</strong>day.<br />
<strong>American</strong> Heart Association<br />
Journal Advertising<br />
7272 Greenville Avenue<br />
Dallas, TX 75231-4596<br />
Telephone (214) 706-1426 Fax (214) 691-6342<br />
©1992, Amencan Heart Association 2037<br />
G. TOTAL (Swn of E. Fl a-d 2-Aht4-1d4l e pres - shown in A) 4 092 4, - nn<br />
ieotify that the statements made by<br />
51. it Ediii Pb.h. M...g<br />
me above are correct ad complete .;e Direc<strong>to</strong>r, Scientific Publishing<br />
PS Form 3526, Januy i00i (S-,o.voo nsonrverse)
Continued from page A 1573<br />
Abroad<br />
1992<br />
Dec 3-6: First International Conference on Heart and<br />
Hypertension. Hotel Taj Intercontinental, Bombay,<br />
India. Organized by National Council of Hypertension<br />
and cosponsored by University of Alabama<br />
School of Medicine, Birmingham. Inquiries: Dr P.J.<br />
Mehta, Hari Bhavan, 64, Pedder Road, Bombay 400<br />
026, India. Tel 3863349/3884575. Fax 00-91-22-363-<br />
3606.<br />
Dec 4-5: Ninth Congress: The Ischemic Heart. Palais des<br />
Congres, Paris. Sponsored by L'Information Cardiologique.<br />
Inquiries: Dr Castillo Fenoy, Centre Cardiologique<br />
du Nord, 32-34, Rue des Moulins Gemeaux,<br />
93200 Saint-Denis, France. Tel 1-49-33-41-<br />
41.<br />
Dec 4-5: Seventh Congress ofArteres et Veines: The Carotid<br />
Stenosis. Palais de Congres, Paris. Inquiries: Publications<br />
Medicales, 77 bis rue des Chesneaux, 95160<br />
Mortmorency, France. Tel 1-34-17-68-88. Fax 1-34-<br />
28-17-59.<br />
Dec 4-6: First Joint Symposium on New Directions in<br />
Cardiovascular Surgery and Cardiology in the '90s.<br />
New Delhi, India. Sponsored by Escorts Heart Institute<br />
and <strong>Research</strong> Centre, New Delhi, India, and<br />
New York University Medical Center, New York.<br />
Inquiries: Escorts Heart Institute and <strong>Research</strong> Centre,<br />
Department of Surgery, Okhla Road, New<br />
Delhi, India 110 025 (tel 91-11-683-7008, ext<br />
4210,4231,4233; fax 91-11-683-2605) or Joan O'Connell,<br />
Noninvasive Cardiology, New York University<br />
Medical Center, 566 First Ave, Room HW 228, New<br />
York, NY 10016 (tel 212-263-5665; fax 212-263-<br />
8461).<br />
Dec 7-11: International Congress on Neurology and Neurosurgery<br />
and the Third International Symposium<br />
on Epilepsy. Havana International Conference Center,<br />
Havana, Cuba. Inquiries: Prof Ot<strong>to</strong> Hernandez<br />
Cossio, President of the Organizing Committee,<br />
Apartado 4248, Zona Postal 4, Ciudad de La Habana<br />
10400, Cuba. Tel 32-7825. Fax 22-8382 and 20-2350.<br />
1993<br />
Jan 12-14: First International Stress Echo Symposium.<br />
Palazzo dei Congressi, Pisa, Italy. Sponsored by the<br />
Working Group of Echocardiography of the European<br />
Society of Cardiology, Societa Italiana di Ecografia<br />
Cardiovascolare, International Cardiac<br />
Doppler Society, National <strong>Research</strong> Council, and<br />
the University of Pisa. Dr Eugenio Picano, scientific<br />
secretariat. Prof Alessandro Distante, president. Inquiries:<br />
Mrs Gloria Boni and Ms Claudia Taddei,<br />
Institute of Clinical Physiology, CNR, and University<br />
of Pisa, Via Savi, 8 - 56100 Pisa, Italy. Tel<br />
0039-50-583286 or 592391. Fax 0039-50-553461.<br />
Jan 12-15: Molecular Basis of Ion Channels and Recep<strong>to</strong>rs<br />
Involved in Nerve Excitation, Synaptic Transmission,<br />
and Muscle Contraction. Ibuka Memorial Hall,<br />
Waseda University, Tokyo. Sponsored by The New<br />
York Academy of Sciences. Inquiries: Conference<br />
Meetings Calendar<br />
A1575<br />
Department, The New York Academy of Sciences, 2<br />
East 63rd St, New York, NY 10021. Tel 212-838-<br />
0230. Fax 212-888-2894.<br />
Jan 20-21: Nitrogen Monoxide. Les Deux Alpes, France.<br />
Sponsored by the Free Radical Club CERLIB. Inquiries:<br />
Arlette Alcaraz, Labora<strong>to</strong>ire Biochimie C<br />
(Pr Favier), CHRUG 38700 La Tronche, France. Tel<br />
33-76765754. Fax 33-76426664.<br />
Feb 4-6: Eighth International Congress on Echocardiography.<br />
Cavalieri Hil<strong>to</strong>n Hotel, Rome. Sponsored by<br />
the Universita Degli Studi di Roma "La Sapienza."<br />
Dr Armando Dagianti and Dr Harvey Feigenbaum,<br />
direc<strong>to</strong>rs. Inquiries: Scientific Secretariat, Department<br />
of Cardiovascular and Respira<strong>to</strong>ry Disease, I<br />
Cardiology, Policlinico Umber<strong>to</strong> I- 00161 Rome,<br />
Italy. Tel 039-6-4463296. Fax 039-6-4469085.<br />
Feb 15-18: First International Congress on Medical-Legal<br />
Aspects of Work Injuries (including aspects of myocardial<br />
infarction). Jerusalem. Sponsored by the Israeli<br />
Association for Labor Law and Social Security,<br />
the National Insurance Institute-Israel, and Hadassa<br />
University Hospital-Jerusalem. Inquiries: The Secretariat<br />
of the First International Congress of Medical-Legal<br />
Aspects of Work Injuries, PO Box 50006,<br />
Tel Aviv 61500, Israel. Fax +972-3-660-325.<br />
Mar 19: European Symposium on Carotid Stenosis: 27th<br />
Congress of the French College of Vascular Medicine.<br />
Paris. Inquiries: D. Melliere, MD, CHU Henri-<br />
Mondor 94010, Creteil, France. Tel 55-1-49-81-24-<br />
05. Fax 33-1-49-81-24-35.<br />
Mar 25-27: Fourth Assisi European Meeting on Cardionephrology.<br />
Assisi, Italy. Sponsored by the University<br />
of Perugia. Prof Mario Timio, meeting organizer.<br />
Abstracts by Dec 30, 1992. Inquiries: Prof Mario<br />
Timio, MD, President, Fourth Assisi European<br />
Meeting on Cardionephrology, Via XX Settembre,<br />
22, 06100-Perugia, Italy. Tel (075)61398-<br />
(0742)339700/339704. Fax 039-74255265.<br />
Apr 4-7: Fifth Congress and 12th Anniversary of the<br />
Pan-African Society of Cardiology: Preventive Cardiology<br />
in Africa. Yaounde, Cameroon. Cosponsored<br />
by the World Health Organization, the International<br />
Society and Federation of Cardiology, and<br />
the AHA and held in conjunction with the Eighth<br />
International Interdisciplinary Conference on Hypertension<br />
in Blacks. Inquiries: Dr. W.F.T. Muna,<br />
BP 5408, Hopital General de Yaounde, Yaounde,<br />
Cameroon. Telephone 237-20-11-22 or 237-20-22-<br />
44. Fax 237-20-09-90.<br />
Apr 7-10: Eighth International Interdisciplinary Conference<br />
on Hypertension in Blacks. Yaounde,<br />
Cameroon. Cosponsored by the World Health Organization,<br />
the International Society and Federation of<br />
Cardiology, and the AHA and held in conjunction<br />
with the Fifth Congress of the Pan-African Society of<br />
Cardiology. Inquiries: John Buckingham, Executive<br />
Direc<strong>to</strong>r, International Society on Hypertension in<br />
Blacks, 69 Butler St, SE, Atlanta, GA 30303. Tel<br />
404-616-3810. Fax 404-688-5169.<br />
Apr 18-21: 57th Medical Association of South Africa<br />
Congress: Medical Excellence in Africa. Sun City,<br />
Bophuthatswana. Inquiries: MASA Congress Conve-
nor, PO Box 20272, Alkantrant, 0005 Republic of<br />
South Africa. Tel 012-329-1359. Fax: 012-329-1345.<br />
Apr 26-28: Two Decades of Chronic Diseases Prevention:<br />
Lessons for International Action. Marina Congress<br />
Center, Helsinki. Inquiries: Symposium Secretariat,<br />
Dr. Heikki J. Korhonen or Ms. Marketta Taimi,<br />
National Public Health Institute, Elimaenkatu 25 A,<br />
00510 Helsinki, Finland. Tel +358-0-146. Fax + 358-<br />
0-146-2185.<br />
May 9-13: 14th European Section Meeting, International<br />
Society for Heart <strong>Research</strong>. Jerusalem. Inquiries: Dr<br />
Arie Pinson, Labora<strong>to</strong>ry for Myocardial <strong>Research</strong>,<br />
The Hebrew University-Hadassah Medical School,<br />
PO Box 1172, Jerusalem 91010, Israel. Fax 972-2-<br />
784010.<br />
May 14-15: International Symposium on Current Aspects<br />
in Atherosclerosis. Ulm, Germany. Sponsored by the<br />
European Society of Cardiology, Working Group on<br />
Epidemiology and Prevention. V. Hombach, MD,<br />
president. Abstracts by Feb 1, 1993. Inquiries: W.<br />
Koenig, MD, Department of Cardiology, University<br />
of Ulm Medical Center, Robert-Koch-Str 8, W-7900<br />
Ulm, Germany. Tel 0049-731-502-4441. Fax 0049-<br />
731-502-4442.<br />
May 16-19: Ninth International Symposium on Brain<br />
Edema. Pacifico Yokohama, Japan. Inquiries: Umeo<br />
I<strong>to</strong>, MD, Department of Neurosurgery, Musashino<br />
Red-Cross Hospital, 1-26-1, Kyonan-cho, Musashino-shi,<br />
Tokyo 180, Japan. Tel 81-422-322-3111.<br />
May 16-20: Second International Symposium on Heart<br />
Failure-Mechanisms and Management. Geneva,<br />
Switzerland. Inquiries: International Society of<br />
Heart Failure, Inc, PO Box 35064, Los Angeles, CA<br />
90035. Tel 310-659-5000. Fax 310-275-8922.<br />
May 18-21: Fifth International Conference on Cerebral<br />
Vasospasm. Hotel MacDonald and the University of<br />
Alberta, Edmon<strong>to</strong>n, and Jasper Park Lodge, Jasper,<br />
Alberta, Canada. Inquiries: Canadian Congress of<br />
Neurological Sciences, 810, 906-12 Avenue SW,<br />
Calgary, Alberta, Canada T2R 1K7. Tel 403-229-<br />
9544. Fax 403-229-1661.<br />
May 19: Advances in Cardiac Ultrasounds. Bari, Italy.<br />
Sponsored by the Institute of Cardiovascular Diseases,<br />
University of Bari, and the Thoraxcentre of<br />
Erasmus University. Inquiries: New Inter Centre,<br />
Via Che Guevara 37/A, 70124 Bari, Italy. Tel +39-<br />
80-5045315. Tel and fax +39-80-5045350.<br />
May 20-21: Role of Cardiac Ultrasounds in Major Cardiac<br />
Syndromes. Bari, Italy. Sponsored by the Institute of<br />
Cardiovascular Diseases, University of Bari, and the<br />
Thoraxcentre of Erasmus University. Inquiries: New<br />
Inter Centre, Via Che Guevara 37/A, 70124 Bari,<br />
Italy. Tel +39-80-5045315. Tel and fax +39-80-<br />
5045350.<br />
May 22-28: XVIth International Symposium on Cerebral<br />
Blood Flow and Metabolism. Sendai International<br />
Center, Sendai, Japan. Sponsored by the International<br />
Society of Cerebral Blood Flow and Metabolism.<br />
Kyuya Kogure and Takashi Yoshimo<strong>to</strong>, cochairmen.<br />
Inquiries: Secretariat BRAIN 93, Tatsuo<br />
Ido, c/o Tohoku Communication Service, Lions<br />
Bldg, Nishikoen 2F, 2-9-13 Omachi, Aobaku, Sendai<br />
]leetings Calendar<br />
A1576<br />
980, Japan. Tel +81-22-214-1778. Fax +81-22-214-<br />
1779 or +81-22-262-5002.<br />
June 2-4: Perioperative Cardiac Care: A Joint Anesthesiology-Cardiology<br />
Symposium. Sonesta Hotel, Eilat,<br />
Israel. Sponsored by the Israel Heart Association<br />
and the Israel Society of Anesthesiologists. Inquiries:<br />
Prof E. Kaplinsky, Heart Institute, Sheba Medical<br />
Center, Tel-Hashomer 52621, Israel. Tel 972-3-<br />
352-303. Fax 972-3-343-888.<br />
June 3-4: European Congress on Arrhythmic Sudden<br />
Cardiac Death. Strasbourg, France. Inquiries: Congres<br />
Louis Pasteur, 19, rue du Marechal Lefebvre,<br />
67100 Strasbourg, France. Tel 33-79-15-00. Fax 33-<br />
88-39-53-18.<br />
June 6-9: Sixth European Symposium on Cardiac Pacing.<br />
Ostend, Belgium. Sponsored by the European Working<br />
Group on Cardiac Pacing. A.E. Aubert, H. Ec<strong>to</strong>r,<br />
and R. Stroobandt, conference chairmen. Abstracts<br />
by Feb 1, 1993. Inquiries: A.E. Aubert, UZ Gasthuisberg<br />
O-N, Herestraat 49, B-3000 Leuven, Belgium.<br />
Tel 32-16-215840. Fax 32-16-215991.<br />
June 9-10: Third International Symposium on Juvenile<br />
Hypertension. Institute of Child Health, London,<br />
UK. Sponsored by the Journal of Human Hypertension.<br />
Inquiries: Jayne Marks, Third International<br />
Symposium on Juvenile Hypertension, Macmillan<br />
Press Ltd, Houndmills, Basings<strong>to</strong>ke, Hants RG21<br />
2XS, UK. Tel +44-256-29242. Fax +44-256-810526.<br />
June 11-12: Congenital Heart Disease in Adults. Toron<strong>to</strong>,<br />
Canada. Peter Liu, MD, and Gary Webb, MD,<br />
direc<strong>to</strong>rs. Inquiries: <strong>American</strong> College of Cardiology,<br />
Extramural Programs, 9111 Old George<strong>to</strong>wn<br />
Rd, Bethesda, MD 20814-1699. Tel 800-257-4739<br />
(outside US and Canada, 301-897-2695). Fax 301-<br />
897-9745.<br />
June 20-23: Diet, Exercise, and Women's Health: 13th<br />
International Puijo Symposium. Sponsored by the<br />
Ministry of Education in Finland and the City of<br />
Kuopio. Prof Matti Uusitupa, MD, PhD, chairman.<br />
Abstracts by Mar 31, 1993. Inquiries: Dr Rainer<br />
Rauramaa, Kuopio <strong>Research</strong> Institute of Exercise<br />
Medicine, Puis<strong>to</strong>katu 20, 70110 Kuopio, Finland. Tel<br />
+358-71-113-677. Fax +358-71-141-515.<br />
June 23-25: 10th Symposium on Echocardiology. Rotterdam,<br />
The Netherlands. Inquiries: Hoboken Congress<br />
Organization, Erasmus University Rotterdam, PO<br />
Box 1738, 3000 DR Rotterdam, The Netherlands.<br />
Tel 31-0-10-408-7880 or 31-0-10-408-7882. Fax 31-<br />
0-10-436-7271.<br />
June 27-July 1: Third International Conference on Preventive<br />
Cardiology. Oslo, Norway. Sponsored by the<br />
International Society and Federation of Cardiology<br />
and its Council on Epidemiology and Prevention, in<br />
cooperation with the World Health Organization,<br />
the European Society of Cardiology, the European<br />
Working Group of Epidemiology and Prevention,<br />
and the AHA's Council on Epidemiology and Prevention.<br />
Inquiries: Prof Rose Stamler, Suite 1102,<br />
680 N Lake Shore Dr, Chicago, IL 60611-4402. Tel<br />
312-908-1717. Fax 312-908-9588.<br />
June 28-30: Fourth Antwerp-La Jolla-Kyo<strong>to</strong> <strong>Research</strong><br />
Conference on Cardiac Function. University of Ant-
werp, Antwerp, Belgium. D.L. Brutsaert, S.U. Sys, J.<br />
Ross Jr, S. Sasayama, organizers. Abstracts by Mar<br />
31, 1993. Inquiries: Dirk L. Brutsaert, MD, PhD,<br />
University of Antwerp, Groenenborderlaan 171,<br />
B-2020 Antwerp, Belgium. Tel +32-3-218-02-77.<br />
Fax +32-3-218-02-76.<br />
July 4-9: Second International Neurotrauma Symposium.<br />
Moat House Hotel, Glasgow, Scotland. Sponsored by<br />
the Neurotrauma Society (USA). Inquiries: Conference<br />
Secretariat, Meeting Makers, 50 Richmond St,<br />
Glasgow, Gi 1XP, Scotland, UK. Tel 041-553-1930.<br />
Fax 041-552-0511.<br />
July 5-8: First International and Eighth European Conference<br />
on Clinical Hemorheology. Vienna. Abstracts<br />
by Feb 15, 1993. Inquiries: A. Hansel, K.L.<br />
Resch, T. Saradeth, Congress Secretariat, Dept Phys<br />
Med Rehab, University of Vienna (AKH), Wahringer<br />
Gurtel 18-20, A-1097 Vienna, Austria. Tel<br />
+43-1-40400-4330. Fax +43-1-40400-5281.<br />
July 29-31: XXth International Congress on Electrocardiology.<br />
Edmon<strong>to</strong>n, Canada. Inquiries: Secretariat,<br />
XXth International Congress on Electrocardiology,<br />
EPICORE Centre, Division of Cardiology, Room<br />
214, Heritage Medical <strong>Research</strong> Bldg, University of<br />
Alberta, Edmon<strong>to</strong>n, Alberta, Canada T6G 2S2.<br />
Aug 1-6: XXXIInd International Congress of Physiological<br />
Sciences. Glasgow, Scotland. Sponsored by the International<br />
Union of Physiological Sciences, the<br />
Royal Society, and the Physiological Society. Inquiries:<br />
CEP Consultants Ltd, 24-26 Albany St, Edinburgh,<br />
EH1 3QH, Scotland.<br />
Aug 6-8: Fifth Asian-Pacific Conference on Doppler and<br />
Echocardiography. Mandarin Hotel, Singapore.<br />
Sponsored by the Academy of Medicine, Singapore;<br />
Singapore National Heart Association; National<br />
University Hospital; and Singapore General Hospital.<br />
Inquiries: Academy of Medicine, Singapore, College<br />
of Medicine Building, 16 College Rd, #01-01,<br />
Singapore 0316. Tel 65-223-8968. Fax 65-225-5155.<br />
Aug 29-Sept 2: XVth Congress of the European Society of<br />
Cardiology. Nice, France. Abstracts by Feb 14, 1993.<br />
Inquiries: ECCO, Central Office, 22, Rue Juste-<br />
Olivier, PO Box 299, CH-1260 Nyon, Switzerland.<br />
Tel 362-13-77. Fax 361-16-79.<br />
Aug 29-Sept 4: 13th International Congress of EEG and<br />
Clinical Neurophysiology. Vancouver, BC, Canada.<br />
Sponsored by the International Federation of Clinical<br />
Neurophysiology. Inquiries: Secretariat, #645-<br />
375 Water St, Vancouver, BC, Canada, V6B 5C6. Tel<br />
604-681-5226. Fax 604-681-2503.<br />
Sept 5-9: 62nd European Atherosclerosis Society Congress.<br />
Jerusalem. Inquiries: Gil-Kenes, 1617 JFK<br />
Blvd, Suite 946, Philadelphia, PA 19103 (tel 800-223-<br />
3855; fax 215-568-0696) (US) or 62nd EAS Congress,<br />
Secretariat, PO Box 50006, Tel Aviv 61500,<br />
Israel (tel +972-3-517-4571; fax +972-3-660-325)<br />
(outside US).<br />
Sept 5-10: 15th World Congress of Neurology. Vancouver,<br />
BC, Canada. Sponsored by the World Federation of<br />
Neurology and the Canadian Neurological Society.<br />
Inquiries: Secretariat, #645-375 Water St, Vancou-<br />
Meetings Calendar<br />
A1577<br />
ver, BC, Canada, V6B 5C6. Tel 604-681-5226. Fax<br />
604-681-2503.<br />
Sept 27-29: First International Conference on Community<br />
Health Nursing <strong>Research</strong>. Edmon<strong>to</strong>n Convention<br />
Centre, Edmon<strong>to</strong>n, Alberta, Canada. Sponsored by<br />
the Edmon<strong>to</strong>n Board of Health. Inquiries: Dr Shirley<br />
Stinson or Ms Karen Mills, International Conference<br />
on Community Health Nursing <strong>Research</strong>, Edmon<strong>to</strong>n<br />
Board of Health, Suite 500, 10216-124 Street, Edmon<strong>to</strong>n,<br />
Alberta, Canada T5N 4A3. Tel 403-482-<br />
1965. Fax 403-482-4194.<br />
Oct 3-6: Third International Meeting.. Biology of Nitric<br />
Oxide. Cologne, Germany. Abstracts by June 1, 1993.<br />
Inquiries: Administrative Secretariat, Christa Bei-<br />
,/wenger, Schwarz-Pharma AG, Congress Organisation,<br />
Alfred-Nobel-Str 10, D-4019 Monheim, Germany.<br />
Tel +49-2173-48-1227. Fax +49-2173-48-1448.<br />
Oct 10-15: International Congress of the International<br />
Association of Inflammation Societies: Inflammation<br />
'93. Austria Center, Vienna, Austria. Inquiries:<br />
ICOS Congress Organisation Service, Schleifmuhlgasse<br />
1, A-1040 Vienna, Austria. Tel 43-1-587-60-<br />
44. Fax 43-1-587-60-59.<br />
Oct 12-17: Eighth Congress of the European Federation of<br />
Societies for Ultrasound in Medicine and Biology-<br />
EUROSON 93. Innsbruck, Austria. Asst Prof Doz Dr<br />
Gert Judmaier, president. Inquiries: Secretariat, The<br />
Eighth Congress of the European Federation of<br />
Societies for Ultrasound in Medicine and Biology,<br />
Anichstrasse 35, 6020 Innsbruck, Austria. Tel 512-<br />
504 ext 3361. Fax 512-504-3391.<br />
Nov 25-27: Inborn Heart Disease: Developmental Mechanism.<br />
Keio Plaza Hotel, Tokyo. Sponsored by the<br />
Akemi Fund of Sankei Press, Japan <strong>Research</strong> Society<br />
of Cardiovascular Disease, and Pediatric Cardiology<br />
Alumni, the Heart Institute of Japan, Tokyo<br />
Women's Medical College. Atsuyoshi Takao, MD,<br />
conference chairman. Inquiries: Japan <strong>Research</strong><br />
Promotion Society for Cardiovascular Disease, Tokyo<br />
Women's Medical College, Kawada-cho 8-1,<br />
Shinjuku-ku, Tokyo 162, Japan. Fax 03-3353-8090.<br />
1994<br />
Mar 21-24: 15th Scientific Meeting of the International<br />
Society of Hypertension. Melbourne, Australia. Prof<br />
C.I. Johns<strong>to</strong>n, chairman. Abstracts by early September<br />
1993. Inquiries: Secretariat, PO Box 29,<br />
Parkville, Vic<strong>to</strong>ria 3052, Australia. Fax 61-3-<br />
3873120. Scientific inquiries: Dr Warwick P. Anderson,<br />
Honorary Secretary, Organizing Committee, c/o<br />
Baker Medical <strong>Research</strong> Institute, PO Box 348,<br />
Prahran, Vic<strong>to</strong>ria 3181, Australia. Fax 61-3-5105472.<br />
July 4-July 7: XXI International Congress on Electrocardiology.<br />
Pacific Convention Plaza Yokohama, Yokohama,<br />
Japan. Inquiries: Masayasu Hiraoka, MD,<br />
Congress Secretariat, Simul International, Inc, Kowa<br />
Building No. 9, 8-10, Akasaka 1-chome, Mina<strong>to</strong>-ku,<br />
Tokyo 107, Japan. Tel +81-3-3586-8691. Fax +81-<br />
3-3586-4531.<br />
July 24-30: XIIth International Congress of Pharmacology.<br />
Montreal, Quebec, Canada. Inquiries: Congress
Secretariat, IUPHAR'94, Conference Services, National<br />
<strong>Research</strong> Council Canada, Ottawa, ON, Canada<br />
K1A OR6. Tel 613-993-9009. Fax 613-957-9828.<br />
Aug 20-25: Seventh International Congress on Obesity.<br />
Westin Harbour Castle Hotel, Toron<strong>to</strong>. Inquiries:<br />
Continuing Education, Faculty of Medicine, University<br />
of Toron<strong>to</strong>, Medical Sciences Building, Toron<strong>to</strong>,<br />
Ontario, M5S 1A8, Canada. Tel 416-978-2718. Fax<br />
416-978-7144.<br />
Sept 10-14: XIIth World Congress of Cardiology and<br />
XVIth Congress of the European Society of Cardiology.<br />
Berlin. Abstracts by Feb 14, 1994. Inquiries:<br />
ECCO, Central Office, 22, Rue Juste-Olivier, PO<br />
Box 299, CH-1260 Nyon, Switzerland. Tel 362-13-77.<br />
Fax 361-16-79.<br />
Nov 20-25: Second International Congress for Pathophysiology.<br />
Kyo<strong>to</strong> International Conference Hall, Kyo<strong>to</strong>,<br />
Japan. Inquiries: Dr Toshiie Sakata, First Department<br />
of Internal Medicine, Ooita Medical University,<br />
1-1 Idaigaoka Hazamacho, Ooita-gun, Ooita,<br />
879-55, Japan (tel 81-975-49-4411; fax 81-975-49-<br />
4217) or Dr Vladimir Shinkarenko, International<br />
Society for Pathophysiology, Baltiyskaya str 8, Mos-<br />
<strong>American</strong> Heart Association<br />
Scientific Sessions<br />
1993 Atlanta, Georgia Nov 8-11<br />
1994 Dallas, Texas Nov 14-17<br />
1995 Anaheim, California Nov 13-16<br />
1996 New Orleans, Louisiana Nov 11-14<br />
Meetings Calendar<br />
A1578<br />
1995<br />
cow 125315, Russia (tel +7-095-152-86-55/151-94-<br />
40; fax +7-095-151-95-40.)<br />
Dec 6-9: XV Inter<strong>American</strong> Congress of Cardiology. Santiago,<br />
Chile. Hosted by the Chilean Society of Cardiology<br />
and Cardiovascular Surgery. Dr Edgardo<br />
Escobar, president, organizing committee. Inquiries:<br />
Secretariat, Los Conquistadores 2251, Dep<strong>to</strong> 4, PO<br />
Box 16854 Providencia, Santiago, Chile. Fax 56-2-<br />
2334715.<br />
1996<br />
June 23-28: 16th Meeting of the International Society of<br />
Hypertension. Scottish Exhibition and Conference<br />
Centre, Glasgow, Scotland. Inquiries: Prof J.L. Reid,<br />
Dept of Medicine and Therapeutics, Gardiner Institute,<br />
Western Infirmary, Glasgow, Gll 6NT, UK.<br />
Tel 041-339-8822, ext 4886.<br />
The <strong>American</strong> Heart Association welcomes news<br />
and meeting announcements of interest <strong>to</strong> physicians,<br />
researchers, and others concerned with cardiovascular<br />
and cerebrovascular medicine. All copy is reviewed by<br />
the Office of Scientific Affairs and may be edited for<br />
style, clarity, and length. Copy is due 90 days before<br />
publication and should be addressed <strong>to</strong> Brinlee Kramer,<br />
Edi<strong>to</strong>r, News From the <strong>American</strong> Heart Association,<br />
7272 Greenville Avenue, Dallas, TX 75231-4596. Fax<br />
214-691-6342.
Can YOU Meet<br />
the Challenge of a<br />
New Frontier?<br />
The past decade has witnessed momen<strong>to</strong>us changes<br />
in the field of cardiovascular research.<br />
New methodologies in cellular, developmental, and molecular<br />
biology have expanded both the breadth and depth of the<br />
questions in cardiovascular biology currently amenable <strong>to</strong><br />
experimental approaches.<br />
Breakthroughs in the cellular and molecular biology of<br />
recep<strong>to</strong>rs and ion channels, <strong>to</strong>gether with improved<br />
understanding of the cellular components of the vascular wall<br />
and myocardium, allow for molecular dissection of many<br />
aspects of the cardiovascular system. The ability <strong>to</strong> mutate<br />
these molecules and study their function in vitro and in<br />
isolated cells is rapidly providing a valuable map of significant<br />
structure-function relationships. This combination of the<br />
reductive power of cellular and molecular biology united with<br />
the integrative approach of organ and whole animal physiology<br />
presages the dawn of a new, more productive era of<br />
cardiovascular science.<br />
<strong>Circulation</strong> <strong>Research</strong>'s new edi<strong>to</strong>rial team has set itself the task<br />
of uniting the reductive and integrative aspects of<br />
cardiovascular research. As researchers continue <strong>to</strong> capitalize<br />
on experimental techniques, <strong>to</strong> address novel questions, and<br />
<strong>to</strong> provide mechanistic explanations that were not - -<br />
possible a decade ago, <strong>Circulation</strong> <strong>Research</strong><br />
will provide a forum for their best I<br />
findings. A<br />
Accelerated review, shortened publication<br />
time, and flexible page allowances<br />
support <strong>Circulation</strong> <strong>Research</strong>'s<br />
commitment <strong>to</strong> facilitate the<br />
synthesis of these two A<br />
approaches, <strong>to</strong> encourage<br />
cellular and molecular biology<br />
research pap ers, andl l<br />
<strong>to</strong> become a leader in<br />
a new era of<br />
cardiovascul,<br />
research.<br />
2039<br />
.,.... I C:1 0<br />
<strong>Research</strong> published and upcoming:<br />
* Behavior of genes directly injected in<strong>to</strong> the rat heart in vivo.<br />
Buttrick, Kass, Kaplan, Leinwand (Albert Einstein)<br />
* Genetically engineered endothelial cells remain adherent and<br />
viable after stent deployment and exposure <strong>to</strong> flow in vitro.<br />
Flugelman, Virmant, Leon, Bowman, Dichek<br />
* Regulated tissue- and cell-specific expression of the human renin<br />
gene in transgenic mice. Sigmund, Jone, Kane, Wu, Lang, Gross<br />
* Antisense nonmuscle myosin heavy chain and c-myb<br />
oligonucleotides suppress smooth muscle cell proliferation in<br />
vitro. Simons, Rosenberg<br />
Be part of the future;<br />
submit your next paper <strong>to</strong><br />
<strong>Circulation</strong> <strong>Research</strong>.<br />
For a free sample copy of <strong>Circulation</strong> <strong>Research</strong>, contact:<br />
Q<strong>American</strong> Heart Association<br />
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