AMERICAN HEART ASSOCIATION, INC. - Circulation
AMERICAN HEART ASSOCIATION, INC. - Circulation
AMERICAN HEART ASSOCIATION, INC. - Circulation
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<strong>AMERICAN</strong> <strong>HEART</strong> <strong>ASSOCIATION</strong>, <strong>INC</strong>.<br />
GRANTS-IN-AID<br />
Applications for American Heart Associ-<br />
.ation Research Grants-in-Aid to qualifying<br />
institutions, including grants to basic science<br />
studies not directly related to the cardiovascular<br />
field,.should be filed before the deadline,<br />
December 1, 1951. Information and<br />
forms may be obtained from the Medical<br />
Director.<br />
SCIENTIFIC COUNCIL<br />
COMM ITTEE<br />
Dr. How ard B. Sprague, Chairman of the<br />
Association's S(ientific Council, has appointed<br />
a Committee uinder the Chairmanship of Dr.<br />
Robert W. Wilkins of Boston to recommend a<br />
plan of reorganization for the Council, including<br />
procedures for membership in line with the<br />
new membership policy. The organizational<br />
changes will enable physician members to participate<br />
actively in the work of various sections<br />
of the council. The Committee's report will be<br />
presented at the next annual meeting of the<br />
Scientific Council in April, 1952.<br />
ANNUAL MEETING<br />
RESERVATIONS<br />
All those planning to atteiid the Association's<br />
Annual Meeting anid Scientific Sessions<br />
at the Hotel Statler, Cleveland, April 18-20,<br />
1952, should make room reservations with the<br />
Housing Bureau, M\1r. 1Iartin C. Dwyer, 511<br />
Terminal Bldg., Clevelanid, at the earliest possible<br />
date.<br />
PROGRAM COMMITTEE<br />
The full Program Committee for the Annual<br />
Scientific Sessions of the Association, to be held<br />
in Cleveland April 18 and 19, 1952, is as follows:<br />
Irvine H. Page, M.i.D., Chairman, Cleveland;<br />
Edgar V. Allen, M.D., Rochester, Minn.;<br />
1775 BROADWAY, NEW YORK 19, N. Y.<br />
Telephone Plaza 7-2045<br />
795<br />
Benjamin B3aker, .Jr., M.I)., Baltimore; Paul<br />
B. Beeson, M.D)., Atlanta; RZobert A. B1uce,<br />
MA)., Seattle; Albert I)orfman, M.D., Chi-<br />
(ago; Thomas J. Dry, M.)., Rochester, Mmii.;<br />
G1. LymanIDuff, M.D., \Montreal; F. Lowell<br />
1)unin, M)., Omaha; .J. Russell Elkinton,<br />
M.D., Philadelphia; Thomas Findley, .r.,<br />
M.)., New Orleans; Arthur .1. Geiger, M\I.D.,<br />
New Haven; John WV. Gofman, M.)., Berkeley,<br />
Calif.; D)wight E. Harken, 'M.D., Boston;<br />
Howard E. Heyer, M.D., I)allas; Charles E.<br />
Kossman, M.D., New York; Louis B. LaPlace,<br />
M.D., Philadelphia; Victor Lorber, -M.D.,<br />
Cleveland; Helen E. Mlartin, M.D., So. Pasadena,<br />
Calif.; Arthur J. M~errill, M.D., Atlanta;<br />
W. F. H. M. Mommaerts, M.D., Durham:<br />
Alan Moritz, M.D., Cleveland; George A.<br />
Porter,<br />
Perera, M.D., New York; Reno II.<br />
M.D., Richmond, Va.; Lowell A. Rantz, -M.D.,<br />
San Francisco; Francis F. Rosenbaum, M\.D.,<br />
Milwaukee; Francis F. Schwventker, 1M.D., Baltimore;<br />
James A. Shannon, M.D., Bethesda,<br />
Md.; Jeremiah Stamler, MI)., Chicago; Frederick<br />
.J. Stare, M.D., Boston; Helen B. Taussig,<br />
M.D., Baltimore; George E. Wakerlin, M.D.,<br />
Chicago; James V. Warren, iM\.., Atlanta;<br />
Carl .J. Wiggers, i\I.D., Cleveland.<br />
Those wishing to present papers are reminded<br />
that an abstract, in triplicate, not exceeding<br />
300 words, should be sent before Janiuary<br />
1, to Dr. Irvine H. Page, Cleveland Clinic,<br />
2020 E. 93 Street, Cleveland 6, Ohio.<br />
SECTION ON CIRCULATION<br />
Hugh -Montgomery, M1.D., Philadelphia, has<br />
been (hosen Chairmaii of the Section on <strong>Circulation</strong><br />
of the Association's Scientific Council.<br />
Nelson Barker, 1\I .D., Rochester, Minn., was<br />
named Vice-Chairman and Grace M. Roth,<br />
I.MD., also of Rochester was named Secretary-<br />
Treasurer.<br />
<strong>Circulation</strong>,<br />
Vo lume IV, November, 195T
796<br />
"RECOMMENDATIONS FOR<br />
BLOOD PRESSURE DETERMINATIONS"<br />
The Association's "Recommendations for<br />
Human Blood Pressure Determinations by<br />
Sphygmomanometers," printed simultaneously<br />
in the October issue of CIRCULATIONW and<br />
the October 13 issue of the Journal of the<br />
American Medical Association will be available<br />
in booklet form. Application should be<br />
made to the National Office, 1775 Broadway,<br />
New York 19, N. Y., or to affiliated heart associations.<br />
<strong>HEART</strong> BULLETIN<br />
SUBSCRIPTIONS<br />
Plans have recently been announced for<br />
sponsorship of subscriptions oni a statewide basis<br />
to the projected bimonthly "Heart Bulle-<br />
<strong>AMERICAN</strong> <strong>HEART</strong> <strong>ASSOCIATION</strong><br />
tin," which is scheduled for publication starting<br />
early next year.<br />
The price per annual subscription will be<br />
S1.56 including postage, when purchased by a<br />
local or state agency an affiliated Heart Association,<br />
State Medical Society, or State Health<br />
Department for most of the physicians in a<br />
state.<br />
The "Heart Bulletin" will be published by<br />
the Medical Arts Publishing Foundation, a<br />
nonprofit public service institution in Houston,<br />
Texas. The magazine will be designed for physicians<br />
in general practice to stimulate their<br />
interest in cardiovascular-renal diseases. It will<br />
not duplicate any other publication of the AHA.<br />
An Advisory Board composed of specialists in<br />
the field will be selected in consultation with<br />
the American Heart Association and the IT. S.<br />
Public Health Service.
CIRCULATION-THE JOURNAL OF THE <strong>AMERICAN</strong> <strong>HEART</strong> <strong>ASSOCIATION</strong><br />
Paroxysmal / I<br />
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in Congestive Heart Failure<br />
KIOPHYLLIN®<br />
-in tablet form may provide desired relief of the labored breathing<br />
and the sense of suffocation and oppression so characteristic of congestive<br />
heart failure.<br />
Kiophyllin is particularly applicable in the management of the degenerative<br />
diseases such as cardiac asthma, arteriosclerosis, hypertension,<br />
angina, bronchitis and chronic syphilitic aortitis, because of the<br />
complementary action of its three components. Aminophyllin (150<br />
mg.) is a myocardial stimulant and diuretic; potassium iodide (125 mg.)<br />
is a resorptive and liquefactive agent; phenobarbital (15 mg.) provides<br />
useful sedation.<br />
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CIRCULATION-THE JOURNAL OF THE <strong>AMERICAN</strong> <strong>HEART</strong> <strong>ASSOCIATION</strong><br />
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CANCER CYTOLOGY<br />
OF THE UTERUS<br />
Introducing a Concept of<br />
Cervical Cell Pathology<br />
By J. ERNEST AYRE, M.D., Director,<br />
Dade County Cancer Institute, Cancer Cytology<br />
Center; and Chief, Cancer Research Department,<br />
Medical Research Foundation of<br />
Dade County, Miami, Fla.<br />
424 pages<br />
bibl., index<br />
362 illus. (79 in color)<br />
$14.50<br />
Here is an outstanding contribution to the science of<br />
cells, a dynamic new concept-lucidly described, superbly<br />
illustrated. In large atlas format, with text and<br />
halftone figures supplemented by 79 magnificent fullcolor<br />
plates, it should stimulate even greater activity<br />
in early cancer detection and prevention.<br />
SUMMARIZED CONTENTS<br />
Development of Concept. . .Technics in Common<br />
Use in Gynecytology. ..Classification of Normal Cell<br />
Types. . .Inflammatory Cell Types. . .Early Anaplastic<br />
Cells-"The Precancer Cell-Complex".. .Pre-invasion<br />
Carcinoma. . .Epidermoid Carcinoma of the<br />
Cervix... .Adenocarcinoma and Other Genital Malignancies.<br />
. .Technics for Total Biopsy.<br />
Grune & Stratton, Inc.<br />
381 Fourth Avenue New York 16
CIRCULATION-THE JOURNAL OF THE <strong>AMERICAN</strong> <strong>HEART</strong> <strong>ASSOCIATION</strong><br />
Capable Hands<br />
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Your patient at the Spa is in capable hands. The<br />
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Here in a restful setting of great natural beauty,<br />
a person suffering from cardiac disorders of a<br />
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which enables the Spa's naturally carbonated<br />
mineral waters to exert their full measure of therapeutic<br />
benefit.<br />
Thus the Spa lightens your heavy burden, with<br />
added relief in the assurance that your patient<br />
will receive the best of care to prepare him for<br />
your continued medical direction.<br />
Capable physicians are available in Saratoga<br />
Springs for consultation with your patient on the<br />
details of the program.<br />
"PHYSICIAN, GIVE HEED TO THINE OWN HEALTH"<br />
Many physicians have come<br />
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xlvi CIRCULATION-THE JOURNAL OF THE <strong>AMERICAN</strong> <strong>HEART</strong> <strong>ASSOCIATION</strong><br />
Surgical Management of<br />
VASCULAR DISEASES<br />
An Outline of the Surgical Management of Vascular Lesions<br />
and Diseases. For Surgeons, Physicians and Students<br />
By GERALD H. PRATT, M.D., F.A.C.S.<br />
Associate Clinical Professor of Surgery, New York University, Chief of the Vascular Clinic and Associate<br />
Attending Surgeon, Saint Vincent's Hospital; Attending Surgeon, St. Clair Hospital, New York;<br />
Diplomate of American Board of Surgery; Commander, Medical Corps, United States<br />
Naval Reserve<br />
Foreword by W. Wayne Babcock, M.D., Temple University, Philadelphia<br />
IN NO field of medical endeavor have there been such remarkable advances as<br />
in the vascular field. In this timely book Dr. Pratt has assembled, classified<br />
and graphically discussed the sound and accepted methods of cardiovascular<br />
diseases. He has drawn upon the information gained from the treatment of more<br />
than 5000 patients annually and presents<br />
the subject just as it would be given in a<br />
postgraduate course for physicians and<br />
surgeons.<br />
Treatment is emphasized throughout,<br />
but essential anatomic, diagnostic and<br />
pathologic facts are not overlooked. Indications<br />
for and technic of surgical intervention<br />
are detailed and only those methods<br />
which have proven of value are<br />
presented.<br />
Among the problems frequently met for<br />
which new and sound therapeutic measures<br />
are given are complications of occlusive<br />
arterial diseases, thrombosis,<br />
embolism, lymphedema, aneurysms,<br />
hypertension, phlebitis, varicose veins and<br />
their complications of ulcer, inflammation<br />
and dermatitis. Other features include the jj<br />
technic of medical and surgical inter-<br />
ruption of the sympathetic nervous<br />
system system, including temporary nerve block- Arteriovenous aneurysm occurring in the ear of<br />
nerve block- F<br />
a baby shortly after delivery by forceps.<br />
ing and permanent sympathectomy, a legend given in book.)<br />
(Detailed<br />
review of the advances in cardiac surgery<br />
made in the past ten years, and the special technics used in angiography, skin<br />
grafting and the surgical treatment of esophageal varices. Diabetic surgical<br />
management is detailed. Dr. Pratt has included 181 black and white illustrations<br />
and 2 colored plates. Many of these illustrations are drawings made right in<br />
the operating room! Surgeons, internists and postgraduate and undergraduate students<br />
will find in this book the help and guidance so urgently needed in the surgical<br />
management of vascular diseases.<br />
496 Pages. 181 Illustrations and 2 Plates in Color.<br />
(Published July, 1949)<br />
$10.00<br />
aW IA
CIRCULATION-THE JOURNAL OF THE <strong>AMERICAN</strong> <strong>HEART</strong> <strong>ASSOCIATION</strong><br />
Grune & Stratton is pleased to announce the first English.<br />
language edition of a great radiographic classic, arranged by<br />
Dr. James T. Case ..<br />
ROENTGEN-I<br />
DIAGNOSTICSI<br />
H. R. SCHINZ, W. E. BAENSCH, E. FRIEDL, E. UEHLINGER,<br />
First American Edition (based on the Fifth German Edition. English translation arranged by<br />
JAMES T. CASE, M.D., D.M.R.E.<br />
Professor of Radiology Emeritus, Northwestern University Medical School, Chicago.<br />
THIS DEFINITIVE WORK-comprehensive, authoritative, completely up-to-date-which<br />
so long has held an uncontested place in the literature, is now brought to English-reading<br />
physicians in a new edition. Profusely iihitiated with all new plates, many in tWo<br />
colors, it has been greatly revised and enlarged to meet the rapidly growing interest<br />
in diagnostic roentgenology. Bibliographies have been brought up to date with full<br />
international references, including those to the English-language literature.<br />
Written and edited by men eminent in radiology, ROENTGEN-DIAGNOSTICS provides<br />
the specialist with a detailed survey, stressing roentgenology as an essential part of the<br />
entire field of medicine and surgery. With this broad view, the book is also an ideal<br />
manual for the physician who does not specialize in roentgenology yet needs a fuller<br />
understanding of its diagnostic applications to his own medical or surgical problems.<br />
The American edition is being published simultaneously with the Fifth German Edition,<br />
so that readers can consult at an early date the most recent advances in roentgenology.<br />
Volume I is available on a subscription basis. The volumes to follow will<br />
appear at about 6-month intervals, the entire project planned to be complete in 1953:<br />
II. Skeleton (Part 2); III. Thorax; IV. Gastrointestinal Tract; V. Gynecology.<br />
Volume I (Skeleton-Part 1)<br />
868 large format pages<br />
1183 illustrations bibliographies $36.00<br />
GRUNE & STRATTON, <strong>INC</strong>. * New York 16, N. Y.<br />
XI. *xVi.
AI*i*i<br />
E<br />
CIRCULATION-THE JOURNAL OF THE <strong>AMERICAN</strong> <strong>HEART</strong> <strong>ASSOCIATION</strong><br />
GRUNE & STRATTON is privileged to announce to the<br />
medical profession innauguration of a new journal . .<br />
Metabolism<br />
Clinical and Experimental<br />
SAMUEL SOSKIN, M.D., Editor-in-Chief<br />
Director, Medical Research Institute, Michael Reese Hospital;<br />
Dean, Michael Reese Hospital Postgraduate School; Associate<br />
Professor of Medicine, Northwestern University Medical School<br />
with an Editorial Board of 17 eminent men, representing the fields of<br />
NUTRITION, ENDOCRINES, GENETICS, DYSTROPHIES, DIABETES and GOUT. METABO-<br />
LISM's reportage will also include articles on the application of the basic sciences to clinical<br />
metabolism, and the metabolic effects of the growing list of specific drugs, biologicals<br />
and antibiotics. Special departments will provide abstracts of current literature appropriate<br />
to the Journal's subject matter, book reviews, editorial discussion and clinical reports<br />
of a summary or review nature.<br />
PURPOSE<br />
The broad field of metabolism enters into the<br />
day-to-day experience of every physician-be he<br />
practitioner or investigator; METABOLISM proposes<br />
to give the profession a truly integrative<br />
approach to the literature of this important field.<br />
The past has seen metabolic papers scattered over<br />
a wide variety of journals; METABOLISMwith<br />
all the impact and advantages of correlation<br />
of a specialized journal-will bring up-to-date,<br />
regular, correlative coverage of the most recent advances<br />
in metabolic science as they apply directly<br />
to the problems of the specialist, general practitioner<br />
and research worker. Balancing the clinical<br />
and the experimental in its contents, ME-<br />
TABOLISM will being together material never<br />
before assembled for the physician between the<br />
covers of an English-language medical journal.<br />
AUDIENCE; COVERAGE<br />
METABOLISM will serve the internist, surgeon,<br />
obstetrician, gynecologist, general practitioner<br />
and research worker as their interests in-<br />
dlude: the utilization of foodstuffs for growth;<br />
tissue repair and energy production; the regulation<br />
of these processes by the endocrine glands<br />
and the central nervous system; hereditary and<br />
acquired abnormalities, and the disturbances in<br />
normal metabolism accompanying various disease<br />
entities; metabolic consequences of therapy with<br />
hormones, vitamins, antibiotics and other drugs.<br />
PUBLICATION DATA<br />
METABOLISM will be published bimonthly<br />
(starting January 1952), each issue containing<br />
about 96 text pages, plus author and topic indexes<br />
completing each annual volume. The Journal will<br />
appear in large 7" x 10" format; with clear, readable<br />
type; printed on coated paper for reproduction<br />
of fine halftone and color illustrations.<br />
The annual subscription is $9.00 (outside the<br />
United States, $10.00).<br />
Issue No. 1 (January) is presently in production.<br />
You are invited to enter your subscription<br />
with the publisher now.<br />
GRUNE & STRATTON, <strong>INC</strong>.<br />
MEDICAL PUBLISHERS 361 FOURTH AVE., NEW YORK CITY 16
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A * , A A A A<br />
CONTENTS<br />
<strong>HEART</strong> DISEASE CASE FINDING BY MEANS OF 70 MILLIMETER PHOTOFLUORO-<br />
GRAPHIC FILMS. GROUP I.<br />
David D. Rutstein, Charles R. Williamson and Felix E. AMoore 641<br />
GROUP II.. Charles R. Williamson, Felix E. Moore, and David D. Rutstein 632<br />
SCREENING TESTS IN MASS SURVEYS AND THEIR USE IN <strong>HEART</strong> DISEASE CASE<br />
FINDING .............................. David D. Ruistein 659<br />
BLOOD LIPIDS AND HUMAN ATHEROSCLEROSIS. II. THE INFLUENCE OF HEPARIN<br />
UPON LIPOPROTEIN METABOLISM .Dean M1. Graham, Thomas P. Lyon,<br />
John TV. Gofman, Hardin B. Jones, Alexander Yankley, John Simonton and<br />
Sidney White 666<br />
EFFECT OF SMALL DOSES OF HEPARIN IN <strong>INC</strong>REASING THE TRANSLUCENCE OF<br />
PLASMA DURING ALIMENTARY LIPEMIA ........ William J. Block, Nelson WV.<br />
Barker and Frank D. MIann (674<br />
rilE DISTRIBUTION OF BODY FLUIDS IN CONGESTIVE <strong>HEART</strong> FAILURE. I. THEO-<br />
RETIC CONSIDERATIONS ................ J. R. Elkinton and R. D. Squires 679<br />
II. ABNORMALITIES IN SERUM ELECTROLYTE CONCENTRATION AND IN ACID-<br />
BASE EQUILIBRIUM....R. D. Squires, R. B. Singer, G. R. MIoffitt, Jr. and J. R.<br />
Elkinton 697<br />
REGIONAL VASOMOTOR TONE IN NIORMOTENSIVE AND HYPERTENSIVE DOGS<br />
Arnold H. Williams and Henry A. Schroeder 70(<br />
PHYSIOLOGIC AND PHYSICAL FACTORS THAT GOVERN THE CLINICAL APPRECIATION<br />
OF CARDIAC THRILLS<br />
Timothy P. Counihan, Maurice B. Rappaport and Howard B. Sprague 716<br />
THE ACTION OF SEVERAL CARDIAC GLYCOSIDES ON CONDUCTION VELOCITY AND<br />
VENTRICULAR EXCITABILITY IN THE DOG <strong>HEART</strong><br />
Gordon K. Moe and Rafael ~e'ndez 729<br />
THE DYE DILUTION METHOD FOR DESCRIBING THE CENTRAL CIRCULATION. AN<br />
ANALYSIS OF FACTORS SHAPING THE TIME-CONCENTRATION CURVES.<br />
Elliott V. Newman, Margaret Merrell, Abraham Genecin, Carlos Monge,<br />
William R. Mlfilnor and William P. McKeever 735<br />
EXPERIMENTAL ARTERIAL DISEASE. I. THE REACTION OF THE PULMONARY ARTERY<br />
TO MINUTE EMBOLI OF BLOOD CLOT<br />
William B. Wartman, Robert B. Jennings and Bryan Hudson 747<br />
II. THE REACTION OF THE PULMONARY ARTERY TO EMBOLI OF FILTER PAPER<br />
FIBERS ... WIilliam B. Wartman, Bryan Hudson and Robert B. Jennings 756<br />
CLINICAL PROGRESS: THE MANAGEMENT OF ACUTE CARDIAC EMERGENCIES<br />
Clarence E. de la Chapelle and 0. Alan Rose 764<br />
ABSTRACTS ...................................... ...... 775<br />
<strong>AMERICAN</strong> <strong>HEART</strong> <strong>ASSOCIATION</strong> ........................................ 7 ...<br />
95