from the director - Georgetown University
from the director - Georgetown University
from the director - Georgetown University
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<strong>from</strong> <strong>the</strong> <strong>director</strong><br />
Over <strong>the</strong> past year at Lombardi we have<br />
conducted a rigorous strategic planning<br />
process and in doing so have reinforced <strong>the</strong><br />
elements that make up our mission:<br />
n patient care<br />
n research<br />
n education<br />
n community<br />
These elements have always been at our<br />
core, but as we move forward, we find con-<br />
tinued inspiration in <strong>the</strong> important new<br />
ways that we can address each of <strong>the</strong>se<br />
critical areas of Lombardi’s mission.<br />
These four elements of our mission do not<br />
exist in a vacuum—<strong>the</strong>y are intimately con-<br />
nected:<br />
� Patient care is impacted by our<br />
research findings,<br />
� Our education activities are anchored in<br />
<strong>the</strong> patient care and research activities,<br />
� Our community initiatives seek to<br />
provide education, patient care, and<br />
venues for research.<br />
This report highlights some of <strong>the</strong> exciting<br />
advances at Lombardi <strong>from</strong> 2008, within<br />
each of <strong>the</strong>se four mission elements, as<br />
well as across <strong>the</strong>m.<br />
I would like to end by thanking <strong>the</strong> many<br />
dedicated friends of Lombardi who make<br />
possible our advances in <strong>the</strong> fight against<br />
cancer. Your support makes an impact<br />
every single day.<br />
Louis m. Weiner, md<br />
Director<br />
<strong>Georgetown</strong> Lombardi Comprehensive<br />
Cancer Center<br />
1
2<br />
Lombardi defeats cancer through scientific discovery and<br />
cutting-edge medicine, guided by <strong>the</strong> principle of cura personalis—<br />
care of <strong>the</strong> whole person.<br />
patient care �� Lombardi clinicialns are dedicated to providing <strong>the</strong> best professional care,<br />
delivered with compassion for all patients. Lombardi’s internationally-renowned physicians treat<br />
virtually every type of cancer, including breast, lung, colorectal, prostate, head and neck, and<br />
cancers of <strong>the</strong> blood. Lombardi patients have access to multi-disciplinary teams of specialists,<br />
which include oncologists, surgeons, and radiation oncologists. Complementing our state-of-<strong>the</strong>-<br />
art cancer care, we offer a program of innovative clinical trials and a full range of supportive care<br />
services to improve <strong>the</strong> health and quality of life of our patients and <strong>the</strong>ir families<br />
research �� Lombardi’s world-renowned scientists are discovering cancer risk factors, designing<br />
effective prevention strategies, and learning how to detect cancers at <strong>the</strong>ir earliest stages. Above<br />
all, <strong>the</strong>y are developing and testing <strong>the</strong> cancer treatments of tomorrow—targeted <strong>the</strong>rapies that<br />
will improve both survival and quality of life. Our researchers work in <strong>the</strong> lab, in <strong>the</strong> classroom, in<br />
<strong>the</strong> clinic, and in <strong>the</strong> community to help answer <strong>the</strong> biggest questions in cancer research and we<br />
are making progress toward <strong>the</strong> ultimate goal: defeating cancer.<br />
education �� Lombardi is committed to <strong>the</strong> education and training of tomorrow’s leaders in<br />
cancer treatment and research. Our education and training programs span all levels of learning—<br />
<strong>from</strong> programs for high school students to postdoctoral fellowships. The Cancer Center offers<br />
four masters degrees as well as a doctorate in Tumor Biology. Lombardi’s clinical fellowship in<br />
hematology/oncology is one of <strong>the</strong> leading programs of its kind. Lombardi educates physicians,<br />
scientists, and health care professionals committed to <strong>the</strong> care of o<strong>the</strong>rs and <strong>the</strong> health needs of<br />
society—always integrating educational excellence, ethics and a commitment to community.<br />
community �� Lombardi is a resource for our community: locally, for residents of Washington,<br />
DC; regionally, as <strong>the</strong> only Comprehensive Cancer Center in <strong>the</strong> greater metropolitan area; and<br />
nationally and internationally by advancing <strong>the</strong> standard of cancer care through our research.<br />
Lombardi is particularly dedicated to serving <strong>the</strong> population of <strong>the</strong> Washington, DC area, which<br />
has some of <strong>the</strong> highest cancer incidence and death rates in <strong>the</strong> country. Our goal is to reduce<br />
disparities and <strong>the</strong> cancer burden among different ethnic minority groups and underserved populations<br />
of <strong>the</strong> District of Columbia.
leading<br />
by example<br />
Lombardi’s impact on <strong>the</strong> field<br />
of oncology has been driven<br />
by highly specialized efforts<br />
to transform cancer research<br />
and care. In 2008 we launched<br />
two new initiatives dedicated to<br />
doing just that: <strong>the</strong> <strong>Georgetown</strong><br />
Database of Cancer and <strong>the</strong><br />
Health Disparities Initiative.<br />
3
4<br />
leading by example<br />
LefT TO rIGHT:<br />
claudine isaacs, md<br />
co-Leader, Breast Program & medical oncologist<br />
subha madhavan, phd<br />
Director, Clinical Research Informatics<br />
louis Weiner, md<br />
Director, <strong>Georgetown</strong> Lombardi Comprehensive<br />
Cancer Center<br />
robert clarke, phd, dsc<br />
co-Leader, Breast Cancer Program & basic scientist<br />
<strong>the</strong> vision behind G-doc<br />
One year ago, Louis M. Weiner, MD, was named Director of <strong>the</strong><br />
<strong>Georgetown</strong> Lombardi Comprehensive Cancer Center. His vision<br />
included a novel approach to bringing advances in research and<br />
treatment into practice for <strong>the</strong> community. Dr. Weiner’s vision has<br />
manifested itself as <strong>the</strong> <strong>Georgetown</strong> Database of Cancer (G-DOC),<br />
a tool under development that promises to deliver on <strong>the</strong> founding<br />
principle of Lombardi and <strong>Georgetown</strong> <strong>University</strong> Medical Center,<br />
cura personalis, or <strong>the</strong> care of <strong>the</strong> whole person.
The <strong>Georgetown</strong> Database<br />
of Cancer<br />
<strong>the</strong> <strong>Georgetown</strong> database of cancer (G-doc) is a major step toward personalized medicine, an essential concept<br />
when dealing with <strong>the</strong> unique nature of cancer.<br />
dr. Weiner � �The G-DOC is a mechanism to bring all<br />
data for one patient toge<strong>the</strong>r, and <strong>the</strong>n compare it to<br />
<strong>the</strong> same of data <strong>from</strong> every o<strong>the</strong>r patient with a similar<br />
disease. By comparing this data, Lombardi researchers<br />
seek to identify <strong>the</strong> factors that most reliably track with<br />
clinical outcomes. The tool is in fact a series of databases,<br />
combining clinical information <strong>from</strong> patients with<br />
a database containing analyses of <strong>the</strong> molecular characteristics<br />
of each patient’s cancer. Some have estimated<br />
that every patient will generate about 1,000,000,000,<br />
000,000,000,000,000,000,000,000,000,000<br />
[or 10 39 ] bytes of data for analysis. This includes information<br />
ranging <strong>from</strong> molecular data about DNA, proteins,<br />
and o<strong>the</strong>r markers in <strong>the</strong> cancer cells, imaging scans,<br />
and treatment information.<br />
“ <strong>Georgetown</strong> and its Lombardi comprehensive cancer<br />
center are committed to reducing <strong>the</strong> burden of cancer<br />
through <strong>the</strong> discovery and early adoption of cuttingedge<br />
systems biology based tools.”<br />
dr. madhavan �� Subha Madhavan, MS, PhD, was<br />
named Lombardi’s first Director of Clinical research<br />
Informatics in October of 2008. She was recruited to<br />
Lombardi <strong>from</strong> <strong>the</strong> National Cancer Institute to coordin-<br />
ate combining <strong>the</strong> existing databases into <strong>the</strong> new in-<br />
frastructure. G-DOC will take advantage of standards<br />
and best practices <strong>from</strong> o<strong>the</strong>r large-scale informatics<br />
projects to help integrate <strong>the</strong> wide variety of patient data<br />
it will hold.<br />
“ although we are still in <strong>the</strong> early stages, my hope<br />
is that implementation of G-doc will increase <strong>the</strong><br />
amount of useful information available to physicians,<br />
allowing <strong>the</strong>m to tailor treatments more specifically<br />
and accurately.”<br />
dr. cLarke �� robert Clarke, PhD, DSc, is a basic sci-<br />
entist whose research focuses on correlating gene ex-<br />
pression with clinical characteristics of cancer in order<br />
to identify options for more personalized treatments.<br />
G-DOC’s collection of patient disease and treatment<br />
information will allow researchers like Dr. Clarke to<br />
make connections between outcomes and <strong>the</strong> clinical<br />
and molecular characteristics of cancer. In <strong>the</strong> process,<br />
he and o<strong>the</strong>r scientists will discover new ways to more<br />
effectively attack cancer cells, creating many targets for<br />
new cancer drugs.<br />
“ <strong>the</strong>re are millions of proteins in <strong>the</strong> body, and we can<br />
measure if one is switched on and ano<strong>the</strong>r off. but <strong>the</strong><br />
problem is that we can’t tell which one is important<br />
for an individual patient’s cancer. G-doc represents<br />
a major step forward in addressing this dilemma.”<br />
dr. isaacs �� Claudine Isaacs, MD, is <strong>the</strong> <strong>director</strong> of<br />
Lombardi’s familial Cancer registry, which tracks one of<br />
<strong>the</strong> nation’s largest collections of individuals <strong>from</strong> high-<br />
risk breast cancer families. The registry will become an<br />
anchor in <strong>the</strong> larger G-DOC—and will be one of <strong>the</strong> first<br />
existing databases to be incorporated into <strong>the</strong> new infrastructure.<br />
The pilot projects in preparation for 2009 will<br />
study how <strong>the</strong> 10 39 bytes of patient information can be<br />
most effectively presented to <strong>the</strong> doctors and nurses who<br />
provide care to Lombardi’s patients. Some estimates<br />
suggest that only 20 percent of available information<br />
about a patient’s cancer is used in <strong>the</strong> course of his or<br />
her care.<br />
“ this pooled information will not only allow physicians<br />
to identify and treat <strong>the</strong> specific subtypes of cancer,<br />
but will also allow scientists to better understand <strong>the</strong><br />
causes of cancer and effects of treatment.”<br />
5
6<br />
leading by example<br />
associate <strong>director</strong> for<br />
minority heaLth & disparities<br />
Lucile L. Adams-Campbell, PhD, an<br />
internationally-recognized expert on<br />
health disparities, was recruited to<br />
Lombardi in June 2008. Just a few<br />
weeks after joining <strong>Georgetown</strong>,<br />
she was elected to <strong>the</strong> prestigious<br />
Institute of Medicine, one of science<br />
and medicine’s highest honors.<br />
A Washington, DC native and life-<br />
long resident, Dr. Adams-Campbell<br />
has devoted her career to identifying<br />
and working to address cancer<br />
health disparities through research,<br />
community outreach, and education.<br />
Before coming to <strong>Georgetown</strong>, she<br />
served as <strong>director</strong> of <strong>the</strong> Howard<br />
<strong>University</strong> Cancer Center, a leading<br />
minority-serving institution in <strong>the</strong><br />
District of Columbia.
The Health Disparities Initiative<br />
<strong>the</strong> overarching goal of <strong>the</strong> Lombardi health disparities initiative is to actively engage in research focused on<br />
reducing cancer disparities in <strong>the</strong> district of columbia among <strong>the</strong> underserved and ethnic minority populations<br />
including african-americans, Latinos, and asian americans. <strong>the</strong> initiative will do so by facilitating, stimulating,<br />
and promoting synergy in addressing <strong>the</strong> biological and environmental basis of cancer health disparities via<br />
research, training, communication, and education.<br />
disparities �� Across <strong>the</strong> nation, <strong>the</strong> burden of can-<br />
cer disproportionately impacts minority and o<strong>the</strong>r<br />
underserved populations. This is especially evident in<br />
<strong>the</strong> District of Columbia, which has one of <strong>the</strong> highest<br />
cancer mortality rates in <strong>the</strong> United States. The objec-<br />
tive of <strong>the</strong> Health Disparities Initiative is to address <strong>the</strong><br />
biological and social determinants of cancer disparities,<br />
with particular emphasis on cancer prevention and con-<br />
trol in <strong>the</strong> Washington metropolitan area.<br />
community �� The Initiative works in collaboration<br />
with a Community Advisory Board, comprised of<br />
members representing <strong>the</strong> District of Columbia’s eight<br />
wards. Board members include neighborhood resi-<br />
dents, community-based physicians, non-profit and<br />
community organizations, churches, members of <strong>the</strong><br />
media, and government officials. Through <strong>the</strong>se partnerships,<br />
focus groups and assessments are conducted<br />
to understand <strong>the</strong> community’s needs regarding <strong>the</strong>ir<br />
health experience. Already, <strong>the</strong> Advisory Board has<br />
helped identify several issues, including <strong>the</strong> need to<br />
educate parents about <strong>the</strong> new laws around HPV vaccination<br />
among 6th grade girls in <strong>the</strong> District.<br />
research �� Minorities and underserved populations<br />
are under-represented in cancer research. The Initiative<br />
will focus on community-based research to address <strong>the</strong><br />
interplay between genetics, environment, and cancer<br />
that could potentially reduce cancer disparities among<br />
<strong>the</strong>se communities. One area of particular focus is en-<br />
ergy balance, which includes nutrition, diet, and physical<br />
activity components. The Initiative is studying <strong>the</strong>se<br />
factors coupled with genetics and biology in order to<br />
understand and ultimately reduce <strong>the</strong> high rates of<br />
obesity in <strong>the</strong> District, including its link to breast, prostate,<br />
and colon cancers. Through community-based<br />
participatory research, which enables <strong>the</strong> community<br />
to participate in all aspects of <strong>the</strong> research, <strong>the</strong>y are developing<br />
culturally appropriate interventions to reduce<br />
<strong>the</strong>se cancer disparities.<br />
disseminate �� The District of Columbia has <strong>the</strong><br />
highest estimated percentage of individuals at <strong>the</strong><br />
lowest literacy levels compared to any state in <strong>the</strong><br />
nation. The combination of poor literacy rates and high<br />
cancer morbidity and mortality rates in <strong>the</strong> District warrants<br />
attention. With <strong>the</strong> goal of improving health for all<br />
populations in <strong>the</strong> District, <strong>the</strong> Initiative is implementing<br />
literacy programs and creating culturally appropriate<br />
educational materials that will improve access to<br />
evidence-based cancer information for minorities and<br />
underserved communities.<br />
between 2001 and 2005, <strong>the</strong><br />
district of columbia ranked<br />
first in <strong>the</strong> nation for deaths<br />
due to prostate, cervical, and<br />
breast cancers. <strong>the</strong> initiative<br />
works in collaboration with a<br />
community advisory board to reach<br />
out to <strong>the</strong> underserved communities of<br />
Washington, dc, with an emphasis on<br />
those areas east of <strong>the</strong> river, which are<br />
particularly hard hit (highlighted in<br />
yellow).<br />
7
8<br />
leading by example<br />
Lombardi introduces an<br />
eLectronic medicaL record<br />
Wall cabinets lined with color-coded<br />
patient charts are now a thing of <strong>the</strong><br />
past at Lombardi. In late 2007, <strong>the</strong><br />
Lombardi clinic transitioned to Aria,<br />
an electronic medical record (eMr)<br />
information system.<br />
Designed specifically for oncology<br />
services, Aria aggregates a patient’s<br />
data into a single, organized medical<br />
chart. Nurses and physicians can<br />
access <strong>the</strong> most up-to-date infor-<br />
mation about <strong>the</strong>ir patients’ treatment<br />
<strong>from</strong> any computer terminal.<br />
Part of a national trend, Lombardi<br />
implemented its new eMr in asso-<br />
ciation with Washington Hospital<br />
Center’s Washington Cancer Insti-<br />
tute and franklin Square Hospital,<br />
both sister hospitals in <strong>the</strong> Medstar<br />
Health System.<br />
Clinical Trials<br />
clinical trials play an<br />
important role in both<br />
cancer research and<br />
care. <strong>the</strong>y serve as <strong>the</strong><br />
first step into <strong>the</strong> clinic<br />
for all new <strong>the</strong>rapies,<br />
and represent <strong>the</strong> final<br />
stages of a long and<br />
careful research process.<br />
treatment advances �� Lombardi is home to a robust Phase 1<br />
clinical trials program, which offers access to <strong>the</strong> most advanced<br />
<strong>the</strong>rapies for cancer. These drugs are often first-in-human studies and<br />
represent a critical step in drug development, <strong>from</strong> <strong>the</strong> laboratory to<br />
<strong>the</strong> clinic. As most standard cancer treatments were first studied in<br />
clinical trials, <strong>the</strong>se studies provide an opportunity for <strong>the</strong> patient to<br />
receive a new type of treatment if his/her cancer does not respond<br />
to standard treatment or if <strong>the</strong>re is no standard treatment available.<br />
Closely regulated by <strong>the</strong> <strong>Georgetown</strong> <strong>University</strong>-MedStar Health<br />
Oncology Internal review Board, Lombardi offers access to clinical<br />
trials throughout <strong>the</strong> network of MedStar Health hospitals, <strong>from</strong><br />
Baltimore to Washington, DC.
one mission<br />
patient care<br />
research<br />
education<br />
community<br />
9
10<br />
patient care<br />
“ physicians treating<br />
this groWing population<br />
have a simple,<br />
but poWerful tool for<br />
improving outcomes<br />
Within <strong>the</strong>ir grasp—<br />
spending time to<br />
engage and involve<br />
older Women in <strong>the</strong>ir<br />
breast cancer care.”<br />
Jeanne mandelblatt, md<br />
research<br />
education community
Improving Care for Older<br />
Breast Cancer Patients<br />
In 2006, women age 65 or older made up half of new breast cancer patients, but<br />
in some settings <strong>the</strong>y failed to receive <strong>the</strong> same care as younger women. Seeking<br />
to understand this disparity, Jeanne Mandelblatt, MD, MPH, associate <strong>director</strong> for<br />
population sciences conducted a study about older women with breast cancer.<br />
Dr. Mandelblatt found that, “Older women who perceive<br />
more ageism in <strong>the</strong>ir interaction with providers<br />
are less likely to receive radiation or chemo<strong>the</strong>rapy.”<br />
But today, <strong>the</strong> percentage of women over age 65<br />
receiving chemo<strong>the</strong>rapy exceeds <strong>the</strong> national average,<br />
according to a new study examining treatment decision-<br />
making by older women with early stage breast cancer.<br />
Dr. Mandelblatt, <strong>the</strong> study’s lead investigator, calls this<br />
“an unexpected finding.” The numbers suggest, “Older<br />
women are learning more about <strong>the</strong>ir disease and may<br />
be weighing <strong>the</strong> risks and benefits more thoroughly.”<br />
What accounts for this change? Better communica-<br />
tion between doctors and patients is linked to choosing<br />
to undergo chemo<strong>the</strong>rapy. In Dr. Mandelblatt’s study,<br />
patients for whom <strong>the</strong> benefits <strong>from</strong> chemo<strong>the</strong>rapy were<br />
unclear were placed into a “consider chemo<strong>the</strong>rapy”<br />
group. Within this group, patients who reported a high<br />
research in practice: shared decision-makinG at Lombardi<br />
seventy-three year-old lee hubbard was diagnosed with breast cancer in april<br />
2008. When her breast surgeon at georgetown, constanza cocilovo, md,<br />
recommended she follow-up with an oncologist, she promptly made an appointment<br />
to see Jennifer eng-Wong, md. “<strong>the</strong>re was never any question in my<br />
mind about whe<strong>the</strong>r i needed to get chemo,” she said. “dr. eng-Wong strongly<br />
recommended it, and i followed her advice.” now enrolled in a clinical trial, lee<br />
added, “my doctors and nurses have been very responsive, and i have been very<br />
happy with my care.”<br />
level of communication with <strong>the</strong>ir doctors were most<br />
likely to get supplementary chemo<strong>the</strong>rapy after surgery.<br />
Study results clearly illustrate that patients are<br />
better able to weigh <strong>the</strong> risks and benefits of chemo<strong>the</strong>rapy<br />
with <strong>the</strong>ir doctors’ advice. Breast cancer treatment<br />
“is a good example of a situation where shared<br />
decision-making would be appropriate since equally<br />
effective surgical choices exist and <strong>the</strong>re is uncertainty<br />
about adjuvant <strong>the</strong>rapy,” wrote Dr. Mandelblatt.<br />
Patients involved in shared decision-making also<br />
tended to be more satisfied with <strong>the</strong>ir treatment,<br />
according to Dr. Mandelblatt. “Physicians treating this<br />
growing population have a simple, but powerful tool<br />
for improving outcomes within <strong>the</strong>ir grasp—spending<br />
time to engage and involve older women in <strong>the</strong>ir breast<br />
cancer care,” she concluded.<br />
Lee Hubbard �<br />
11
12<br />
patient care research<br />
education community<br />
“ eWing’s sarcoma is rare.<br />
but our Work has <strong>the</strong><br />
potential to improve<br />
treatment not only<br />
for patients With this<br />
disease but for o<strong>the</strong>rs<br />
Who have cancers<br />
With similar molecular<br />
characteristics.”<br />
Jeffrey toretsky, md
Potential ewing’s Sarcoma Targeted<br />
Therapy Discovered<br />
for over ten years, Jeffrey Toretsky, MD, has sought a cure for ewing’s sarcoma,<br />
a rare childhood cancer resulting <strong>from</strong> a mutation that swaps genes between two<br />
chromosomes. In 2008, he made a major breakthrough when he discovered a<br />
small molecule that could be <strong>the</strong> basis of a new <strong>the</strong>rapy.<br />
The small molecule interrupts binding between<br />
<strong>the</strong> mutated protein, called eWS-fLI1, and one of its<br />
binding partners. Dr. Toretsky and his team had identified<br />
<strong>the</strong> binding partner in 2006, and working with<br />
<strong>Georgetown</strong>’s Drug Discovery Program, led by Milton<br />
Brown, MD, PhD, <strong>the</strong>y identified <strong>the</strong> new molecule,<br />
which fills in <strong>the</strong> “keyhole” on eWS-fLI1 like wax might<br />
block a key <strong>from</strong> entering a lock. This halts <strong>the</strong> growth<br />
of ewing’s sarcoma cancer cells. While several stages<br />
of <strong>the</strong> research process remain before <strong>the</strong> drug can<br />
move into <strong>the</strong> clinic, this could be <strong>the</strong> first targeted<br />
<strong>the</strong>rapy to be developed for ewing’s sarcoma.<br />
ewing’s sarcoma is diagnosed in approximately 500<br />
children each year. Because of <strong>the</strong> relatively small num-<br />
ber of patients diagnosed with <strong>the</strong> disease, <strong>the</strong>re has<br />
been little research investment into new treatments.<br />
So-called “orphan” diseases such as ewing’s garner<br />
little interest <strong>from</strong> pharmaceutical companies who most<br />
Go4<strong>the</strong>GoaL foundation<br />
go4<strong>the</strong>goal foundation was founded in 2006 by richard & beth<br />
stefanacci when <strong>the</strong>ir oldest son richard was diagnosed with<br />
ewing’s sarcoma at age 13. through <strong>the</strong> foundation, <strong>the</strong> stefanaccis<br />
became loyal supporters of dr. toretsky in 2007, giving nearly<br />
$150,000 for instrumentation and a staff member, which greatly<br />
expedited his research. according to <strong>the</strong> stefanaccis, “We were<br />
able to give richard everything but a cure! after his death we were<br />
committed to help find a cure and help children affected by cancer.<br />
Within minutes of meeting dr. toretsky we knew his lab was <strong>the</strong><br />
perfect fit to achieve our foundation’s goal.”<br />
often conduct drug development research. Lombardi’s<br />
Drug Discovery Program provides an academic solution,<br />
enabling basic laboratory research, like Dr. Toretsky’s,<br />
to progress closer to clinical trials.<br />
Since 1999, The Children’s Cancer foundation has<br />
supported Dr. Toretsky’s research, believing in <strong>the</strong><br />
promise of his approach. Their early support for his<br />
revolutionary work contributed to <strong>the</strong> major successes<br />
of <strong>the</strong> past year, which include additional peer-reviewed<br />
funding.<br />
In early 2008, <strong>the</strong> Burroughs-Wellcome fund—<br />
an independent private foundation—awarded him a<br />
prestigious Clinical Scientist Award in Translational<br />
research worth $750,000. The NIH also recently<br />
funded a third r01 grant for Dr. Toretsky, which focuses<br />
on <strong>the</strong> role of cancer stem cells in <strong>the</strong> development of<br />
ewing’s sarcoma.<br />
�Stefanacci family<br />
13
14<br />
patient care research education<br />
community<br />
“ We alWays enJoy having<br />
<strong>the</strong> felloWs around.<br />
<strong>the</strong>re’s a certain energy<br />
and optimism at lombardi<br />
that you Wouldn’t find<br />
in a private practice<br />
environment. it makes<br />
<strong>the</strong> training experience<br />
more interesting and<br />
valuable.”<br />
Jimmy hwang, md
Leading fellowship Program Trains<br />
Next Generation of Oncologists<br />
Lombardi’s Hematology/Oncology fellowship Program is one of <strong>the</strong> top cancer<br />
specialty training programs in <strong>the</strong> country. Balancing clinical training and research<br />
experience, <strong>the</strong> curriculum places fellows at <strong>the</strong> epicenter of cancer research.<br />
founded over twenty years ago, only four to five fellows are accepted to <strong>the</strong> program<br />
each year <strong>from</strong> a pool of over three hundred applicants.<br />
Attending physicians directly supervise each fellow’s<br />
three year training experience to develop <strong>the</strong> best clinicians<br />
and clinical investigators in <strong>the</strong> country. fellows<br />
spend up to two years doing clinical work, seeing<br />
patients in a variety of contexts, and <strong>the</strong> remaining year<br />
conducting research. Upon completion, <strong>the</strong> fellows are<br />
able to practice in both medical oncology and hematology<br />
because <strong>the</strong> program is accredited for subspecialty<br />
training as a combined program by <strong>the</strong> Accreditation<br />
Council for Graduate Medical education.<br />
While <strong>the</strong>re are many o<strong>the</strong>r combined hematology/<br />
oncology programs in <strong>the</strong> country, Lombardi’s is unique<br />
because of <strong>the</strong> wealth of research opportunities and re-<br />
sources available. each fellow has <strong>the</strong> opportunity to<br />
select training in clinical research or translational re-<br />
chief feLLoW dedicated to a career in academic medicine<br />
trishna goswami, md, was selected to serve as chief fellow of lombardi’s hematology/<br />
oncology fellowship program for 2009. a graduate of mcp hahnemann university<br />
medical school (now drexel university college of medicine), dr. goswami completed<br />
her residency in internal medicine at georgetown university hospital before applying<br />
for <strong>the</strong> fellowship. “lombardi is a great training program because it maximizes clinical<br />
care and exposure to novel research,” she said. as a second year fellow, dr. goswami<br />
demonstrated exceptional leadership and communication skills in stressful situations.<br />
“We on <strong>the</strong> faculty look at <strong>the</strong> chief fellow as a paragon for <strong>the</strong> o<strong>the</strong>r fellows, trainees,<br />
and students,” said dr. hwang. “We thought dr. goswami was an outstanding choice<br />
for chief fellow. We are fortunate that she was willing to take on this responsibility<br />
and honor.”<br />
search, which focuses on connecting <strong>the</strong> dots between<br />
laboratory science and patient care.<br />
“It’s sort of like an apprenticeship, in which <strong>the</strong> fellows<br />
learn by seeing,” said Jimmy Hwang, MD, who is head<br />
of <strong>the</strong> fellowship Program and an attending gastrointestinal<br />
oncologist in <strong>the</strong> Lombardi clinic.<br />
fellows often take a leadership role in clinical meetings<br />
among physicians. Throughout <strong>the</strong>ir training, <strong>the</strong>y<br />
are required to lead discussions about <strong>the</strong> latest advances<br />
in cancer care, and are asked to present cases<br />
for discussion by multidisciplinary teams of specialists.<br />
Graduates of <strong>the</strong> program include Lombardi’s Chief<br />
of Hematology/Oncology John L. Marshall, MD, and<br />
Breast Cancer Program Leader Claudine Isaacs, MD.<br />
�Trishna Goswami, MD<br />
15
16<br />
patient care research education<br />
community<br />
“ We Want people to<br />
knoW that breast<br />
cancer doesn’t mean<br />
you’re going to die, and<br />
that early detection<br />
can save your life.”<br />
michelle fenty
Capital Breast Care Center<br />
Provides 5000th Mammogram<br />
In 2008, Lombardi’s Capital Breast Care Center (CBCC) announced it had reached<br />
<strong>the</strong> landmark of 5000 women screened. The CBCC provides extraordinary quality<br />
care regardless of a woman’s ability to pay to underserved women in Washington,<br />
DC—a city in which women die <strong>from</strong> breast cancer at a rate of 65 percent above<br />
<strong>the</strong> national average; <strong>the</strong> highest death rate in <strong>the</strong> country.<br />
It was <strong>the</strong> devastating statistics in Washington, DC,<br />
which first attracted Michelle Cross fenty, JD, <strong>the</strong> first<br />
lady of Washington, DC, to serve as president of <strong>the</strong><br />
CBCC Advisory Council.<br />
“The Capital Breast Care Center works to spread <strong>the</strong><br />
message about <strong>the</strong> dire situation in Washington, DC,<br />
but also encourages women to get yearly mammograms,”<br />
said Mrs. fenty.<br />
Since opening its doors in April 2004, <strong>the</strong> CBCC has<br />
been supported by grants to Lombardi <strong>from</strong> <strong>the</strong> Avon<br />
foundation and <strong>the</strong> Washington, DC Department of<br />
Health, among o<strong>the</strong>rs. The Center serves DC women<br />
who would o<strong>the</strong>rwise not have access to vital services<br />
such as mammograms, genetic testing, patient navigation<br />
and quality care.<br />
“With support <strong>from</strong> Avon and o<strong>the</strong>rs, our goal<br />
kesher nashim : a circLe of Women<br />
<strong>the</strong> members of kesher nashim, a hebrew term meaning “a circle of women”, are<br />
breast cancer survivors <strong>from</strong> congregation beth el of montgomery county, md.<br />
providing support for those newly diagnosed as well as survivors, kesher nashim<br />
also supports <strong>the</strong> efforts of <strong>the</strong> cbcc. <strong>the</strong> group raised over $5,000 for <strong>the</strong> cbcc’s<br />
2008 gift of life breakfast—one of <strong>the</strong> highest grossing tables at <strong>the</strong> event. “We<br />
have a very personal affinity and connection to <strong>the</strong> women that <strong>the</strong> center serves,”<br />
said susan Winarsky. “it’s not a remote concept, and we know how difficult it is to<br />
navigate our complex healthcare system.”<br />
Susan Winarsky, Margaret Rifkind, Naomi Greenwood, and Margery Landon, members of Kesher Nashim �<br />
is to make sure that all women in <strong>the</strong> Washington<br />
metropolitan region learn about breast cancer, dispel<br />
myths and misperceptions, and foster healthy lifestyles<br />
including access for all women to receive breast cancer<br />
screening,” said Peter Shields, MD, deputy <strong>director</strong> of<br />
Lombardi and senior medical <strong>director</strong> of <strong>the</strong> CBCC.<br />
The Center uses a three-pronged approach to combat<br />
breast cancer: offering screening to underserved<br />
and uninsured women, providing a patient navigator to<br />
support women who receive a diagnosis of cancer, and<br />
educating women throughout <strong>the</strong> community about<br />
breast cancer risks and <strong>the</strong> need for screening.<br />
“everyone has lost someone to breast cancer—it’s a<br />
disease that everyone can relate to. My goal is for every-<br />
one in <strong>the</strong> city to know that <strong>the</strong> CBCC is somewhere to<br />
get screened,” said Mrs. fenty.<br />
17
18<br />
lombardi leadership<br />
<strong>director</strong>s<br />
peter g. shields, md<br />
Deputy Director<br />
Professor of Medicine & Oncology<br />
department chairs<br />
louis m. Weiner, md<br />
Chair<br />
Department of Oncology<br />
gregory gagnon, md<br />
Chair<br />
Department of Radiation Medicine<br />
françoise sellier-moseiwitsch, phd<br />
Chair<br />
Department of Biostatistics,<br />
Bioma<strong>the</strong>matics, and Bioinformatics<br />
c. richard schlegel, md, phd<br />
Chair<br />
Department of Pathology<br />
louis m. Weiner, md<br />
Director<br />
<strong>Georgetown</strong> Lombardi<br />
Comprehensive Cancer Center<br />
John l. marshall, md<br />
Associate Director for<br />
Clinical research<br />
Associate Professor of<br />
Medicine & Oncology<br />
anton Wellstein, md, phd<br />
Associate Director for<br />
Basic Science<br />
Professor of Oncology &<br />
Pharmacology<br />
research program leaders<br />
breast cancer<br />
robert clarke, phd, dsc n claudine isaacs, md<br />
Jeanne mandelblatt, md, mph<br />
Associate Director for<br />
Population Sciences<br />
Professor of Medicine & Oncology<br />
The Breast Cancer Program is a clinical translational research<br />
program dedicated to identifying better methods of diagnosis,<br />
treatment, and prevention of breast cancer. The Nina Hyde Center<br />
for Breast Cancer research, part of <strong>the</strong> Breast Cancer Program, is<br />
home to more than 50 Lombardi scientists and physicians striving<br />
to uncover <strong>the</strong> biological basis of <strong>the</strong> many faces of breast<br />
cancer and working toward its prevention and cure. <strong>Georgetown</strong><br />
<strong>University</strong> has been consistently ranked in <strong>the</strong> top 10 institutions<br />
conducting breast cancer research as measured by eSI Thompson<br />
Scientific.<br />
cancer controL<br />
marc schwartz, phd<br />
The Cancer Control Program conducts research across <strong>the</strong> range<br />
of <strong>the</strong> cancer control process <strong>from</strong> risk factors and prevention,<br />
through early detection, to treatment and survivorship. Lombardi’s<br />
program is unique in its inclusion of populations across <strong>the</strong> lifespan—<strong>from</strong><br />
childhood to older age—and translation <strong>from</strong> <strong>the</strong> cellular<br />
to <strong>the</strong> societal and policy level. The overall goal of <strong>the</strong> program<br />
is to develop, evaluate and disseminate innovative cancer control<br />
interventions designed to reduce <strong>the</strong> incidence, morbidity, and<br />
mortality <strong>from</strong> cancer among high-risk populations.
anna t. riegel, phd<br />
Associate Director for<br />
Cancer research education<br />
Professor of Oncology &<br />
Pharmacology<br />
stephen byers, phd<br />
Director of Shared resources<br />
Professor of Oncology<br />
carcinoGenesis, biomarkers & epidemioLoGy<br />
christopher loffredo, phd n fung-lung chung, phd<br />
The Carcinogenesis, Biomarkers and epidemiology Program’s<br />
mission is to understand <strong>the</strong> body’s response to carcinogenesis.<br />
The program focuses its research primarily on <strong>the</strong> genetic and<br />
environmental factors which affect <strong>the</strong> development and progression<br />
of cancer, identifying markers for risk and methods for<br />
prevention. The goal of <strong>the</strong> program is to understand and reduce<br />
cancer incidence, morbidity, and mortality by understanding <strong>the</strong><br />
basis of risk, host response, and carcinogenic processes across<br />
<strong>the</strong> cancer spectrum (cancer development, early disease progression<br />
and survival).<br />
druG discovery & deveLopmentaL <strong>the</strong>rapeutics<br />
milton brown, md, phd �� John l. marshall, md<br />
The Drug Discovery and Developmental Therapeutics Program<br />
focuses on <strong>the</strong> identification and development of novel cancer<br />
treatments. In this program, basic scientists and clinicians collab-<br />
orate to provide Lombardi faculty members with a conduit for<br />
rapid, scientifically-driven cancer drug development. The program<br />
is organized as a drug development “pipeline” with expertise in drug<br />
and target discovery, <strong>the</strong> performance of innovative early Phase<br />
clinical research, and disease-specific Phase II and III clinical<br />
research.<br />
michael p. vander hoek, mhsp<br />
Associate Director for<br />
Administration and Planning<br />
lucile l. adams-campbell, phd<br />
Associate Director for Minority<br />
Health and Health Disparities<br />
Professor of Oncology<br />
GroWth reGuLation of cancer<br />
priscilla furth, md n c. richard schlegel, md, phd<br />
The overall scientific goal of <strong>the</strong> Growth regulation of Cancer<br />
Program is to understand <strong>the</strong> molecular determinants of <strong>the</strong> path-<br />
ophysiological pathways that lead to cancer development. The<br />
research focuses on two basic principles—<strong>the</strong> processes of cancer<br />
initiation and prevention. Specifically, researchers are dedicated<br />
to understanding <strong>the</strong> role of growth factor and hormonal path-<br />
ways, determinants of cell fate, as well as <strong>the</strong> role of virology in<br />
carcinogenesis. The program’s approach is to define <strong>the</strong> molecular<br />
mechanisms that govern cancer development.<br />
moLecuLar tarGets and <strong>the</strong>rapeutic resistance<br />
vicente notario, phd �� eliot rosen, md, phd<br />
As a basic science research program, Molecular Targets & Therapeutic<br />
resistance focuses on <strong>the</strong> mechanisms of <strong>the</strong>rapeutic re-<br />
sistance in tumor and normal cells, including responses to radiation,<br />
chemo<strong>the</strong>rapy agents, and hormonal agents. The ultimate<br />
goal is to apply <strong>the</strong> basic knowledge gained <strong>from</strong> <strong>the</strong>se studies to<br />
improve <strong>the</strong>rapeutic interventions. The overall conceptual framework<br />
of <strong>the</strong> program is based on <strong>the</strong> idea that signaling abnormalities<br />
in cancer are <strong>the</strong> same defects that affect responses to<br />
conventional treatments.<br />
19
20<br />
year in revieW<br />
expressive WritinG improves patient’s WeLLbeinG<br />
Writing about thoughts and feelings related to cancer not only changes <strong>the</strong> way cancer<br />
patients view <strong>the</strong>ir disease, but also benefits both <strong>the</strong>ir physical and mental health. “We<br />
found that just one writing session in a busy cancer clinic where <strong>the</strong> patients are frequently<br />
interrupted can still have a positive impact on patients,” said Nancy P. Morgan, MA-TLA,<br />
writing clinician and <strong>director</strong> of <strong>the</strong> Lombardi Arts and Humanities Program. Ms. Morgan<br />
and her colleagues conducted <strong>the</strong>ir study in <strong>the</strong> clinic waiting area at Lombardi. “I’m pleased<br />
to see that so many of our patients were interested in this kind of <strong>the</strong>rapy,” said Bruce<br />
Cheson, MD, head of hematology at <strong>the</strong> Cancer Center. “Our study supports <strong>the</strong> benefit of<br />
an expressive writing program and <strong>the</strong> ability to integrate such a program into a busy clinic.”<br />
Lombardi pubLishes book for chiLdhood cancer survivors<br />
The Next Step… Crossing <strong>the</strong> Bridge to Survivorship is an educational guide designed<br />
to serve as a long-term resource for pediatric cancer suvivors, with extensive information<br />
about <strong>the</strong> “late effects” of treatment, which may occur many years after<br />
<strong>the</strong>rapy is completed. “The end of cancer treatment is a time of strong emotions<br />
for patients and families,” said Aziza T. Shad, MD, chief of <strong>the</strong> division of pediatric<br />
hematology/oncology at Lombardi, and author of <strong>the</strong> book. “We hope this book<br />
will help ease <strong>the</strong> transition for patients and families <strong>from</strong> active treatment to<br />
follow-up care.” The handbook is customized for each patient to include information<br />
about <strong>the</strong>ir cancer diagnosis and specific treatments.<br />
Genetic testinG and <strong>the</strong> importance of discussinG cancer history<br />
Whe<strong>the</strong>r or not relatives talk about a family’s history of cancer significantly impacts attitudes<br />
and knowledge about genetic counseling and testing for those at moderate risk of developing<br />
cancer. A recent study conducted by Kenneth Tercyak, PhD, at Lombardi’s fisher Center for<br />
familial Cancer research found that mo<strong>the</strong>rs who decided to share breast cancer genetic testing<br />
results with <strong>the</strong>ir children were more satisfied with <strong>the</strong>ir decision than those who decided<br />
not to disclose <strong>the</strong> results. for common cancers, such as breast, colon, and prostate cancer,<br />
20–30% of those affected have a family history of <strong>the</strong>se cancers. Genetic counseling and testing<br />
may be obtained to learn more about cancer risks and options for cancer screening and<br />
prevention.<br />
test can heLp doctors determine treatment chanGes earLier<br />
A simple blood test could tell women with advanced breast cancer whe<strong>the</strong>r or not <strong>the</strong>ir treatments are<br />
working earlier and more reliably than current methods. Under <strong>the</strong> direction of Minetta Liu, MD, medical<br />
oncologist and <strong>director</strong> of translational breast cancer research at Lombardi, researchers measured <strong>the</strong><br />
number of circulating tumor cells (CTCs) in blood collected <strong>from</strong> women with metastatic breast cancer.<br />
The number of CTCs, measured by <strong>the</strong> fDA-approved CellSearch technology, was correlated with disease<br />
response or progression. “The key is to find <strong>the</strong> most effective <strong>the</strong>rapy for each patient. It shouldn’t<br />
take months to figure that out,” Dr. Liu concluded.
patient care<br />
research<br />
anatasha craWford seLected for bouchet society<br />
Anatasha Crawford, a doctoral student in Lombardi’s Tumor Biology<br />
Training Program, has been named a member of <strong>the</strong> prestigious edward<br />
A. Bouchet Graduate Honor Society. The Bouchet Society aims to recog-<br />
nize outstanding scholarly achievement and promote diversity and excel-<br />
lence in doctoral education and <strong>the</strong> professoriate. Ms. Crawford’s dissertation<br />
focuses on how and why cancer becomes resistant over time to<br />
<strong>the</strong>rapy, specifically looking at resistance to antiestrogen treatments for<br />
breast cancer. “I believe that my scholarship, leadership, character, ser-<br />
vice, and advocacy will help me become an accomplished breast cancer<br />
research scientist and more importantly a successful mentor,” she said.<br />
She plans to continue to work in her community and as an advocate for<br />
increasing <strong>the</strong> presence of minorities in PhD programs in <strong>the</strong> field of<br />
biomedical research.<br />
teaminG up to prevent prostate cancer<br />
every year during national prostate cancer awareness week, <strong>the</strong> Department<br />
of Urology at <strong>Georgetown</strong> <strong>University</strong> Hospital and <strong>the</strong> <strong>Georgetown</strong> Lombardi<br />
Comprehensive Cancer Center offer free prostate cancer screening. In 2008,<br />
nearly 200 men were screened by an all-volunteer staff that included <strong>Georgetown</strong><br />
<strong>University</strong> medical students and Hospital physicians. This year, <strong>the</strong> Department of<br />
Urology added a new screening test to <strong>the</strong> traditional PSA test and <strong>the</strong> digital rectal<br />
exam, which requires only a small blood sample to be drawn, and reduces <strong>the</strong><br />
number of false-positive results. The screening has been funded by <strong>the</strong> generosity<br />
of <strong>the</strong> NfL Charities for <strong>the</strong> past ten years.<br />
education community<br />
robert clarke, phd, dsc, mentored both anatasha<br />
crawford and Zachary dobbin, a <strong>Georgetown</strong><br />
university undergraduate student, in his laboratory<br />
at Lombardi, which is dedicated to understanding<br />
<strong>the</strong> molecular biology of breast cancer.<br />
empoWerinG underserved patients<br />
In <strong>the</strong> United States, African American and Latina women are diagnosed with breast cancer<br />
less frequently than white women. But studies show that once diagnosed, <strong>the</strong>se women are<br />
more likely to die of <strong>the</strong>ir disease. Vanessa Sheppard, PhD, an assistant professor at Lombardi,<br />
has developed Sisters Informing Sisters and Latina a Latina, two programs dedicated to helping<br />
African American and Latina breast cancer patients make informed decisions about <strong>the</strong>ir<br />
treatment. Both programs match patients with patient navigators—often breast cancer survivors<br />
<strong>the</strong>mselves—who navigate women through <strong>the</strong> treatment decision process. “I understand<br />
how difficult a time getting a diagnosis is in someone’s life. I want to make sure that women<br />
receive <strong>the</strong> support <strong>the</strong>y need, and reduce—if not eliminate—disparities in healthcare,” Dr.<br />
Sheppard said.<br />
21
22<br />
M I L L I O N S $<br />
40<br />
by <strong>the</strong> numbers<br />
M I L L I O N S $<br />
N U M B E R O F P A T I E N T S<br />
P A T I E N T V I S I T S<br />
N U M B E R O F P A T I E N T S<br />
P A T I E N T V I S I T S<br />
80<br />
60<br />
40<br />
20<br />
0<br />
0<br />
research 600 funding: 2004–2008<br />
600<br />
100<br />
500<br />
80<br />
400<br />
60<br />
300<br />
40200<br />
100<br />
20<br />
600<br />
500<br />
30,000<br />
0<br />
50,000<br />
0<br />
40,000<br />
30,000<br />
20,000<br />
0<br />
2004<br />
10,000 400<br />
M I L L I O N S $<br />
100<br />
80<br />
60<br />
40<br />
20<br />
0<br />
N U M B E R O F P A T I E N T S<br />
300<br />
2004<br />
200<br />
600<br />
2004<br />
2005<br />
500<br />
400<br />
300<br />
200<br />
100<br />
0<br />
2005<br />
2005<br />
2006<br />
2006<br />
400<br />
patient visits: 2004–2008<br />
50,000<br />
300<br />
50,000<br />
200 40,000<br />
40,000<br />
100 30,000<br />
100<br />
20,000<br />
80<br />
10,000<br />
M I L L I O N S $<br />
0<br />
2004<br />
60<br />
0<br />
40<br />
20<br />
N U M B E R O F P A T I E N T S<br />
M I L L I O N S $<br />
P A T I E N T V I S I T S<br />
600<br />
500<br />
100<br />
60<br />
20<br />
P A T I E N T V I S I T S<br />
2004<br />
0<br />
0<br />
N U M B E R O F P A T I E N T S<br />
500<br />
400<br />
300<br />
200<br />
2004<br />
100<br />
2005<br />
0<br />
20,000<br />
10,000<br />
Gastrointestinal<br />
50,000<br />
40,000<br />
30,000<br />
20,000<br />
0<br />
Gastrointestinal<br />
2004<br />
10,000<br />
0<br />
2004<br />
2005<br />
2004<br />
2005<br />
2006<br />
Breast<br />
Genitourinary<br />
2005<br />
2006<br />
2006<br />
2007<br />
2006<br />
2007<br />
2007<br />
Lung<br />
Hematologic<br />
2007<br />
2007<br />
2007<br />
2008<br />
2008<br />
Neurological<br />
2008<br />
Head & Neck<br />
2008<br />
2008<br />
2008<br />
Endocrine<br />
P A T I E N T S E N R O L L E D<br />
8000<br />
7000<br />
6000<br />
5000<br />
4000<br />
3000<br />
2000<br />
1000<br />
0<br />
sources of research funding: 2008*<br />
Skin<br />
P A T I E N T S E N R O L L E D<br />
Gynecologic<br />
P A T I E N T S E N R O L L E D<br />
8000<br />
7000<br />
6000<br />
5000<br />
4000<br />
3000<br />
2000<br />
1000<br />
Interventional<br />
0<br />
8000<br />
7000<br />
6000<br />
5000<br />
4000<br />
3000<br />
2000<br />
1000<br />
Orthopedic<br />
T YPE OF TRIAL<br />
0<br />
Unknown<br />
O<strong>the</strong>r<br />
4000<br />
Non-interventional<br />
3000<br />
Interventional<br />
1000<br />
Interventional<br />
n 53% nih<br />
n 25% o<strong>the</strong>r peer-reviewed<br />
(<strong>from</strong> government and<br />
foundations)<br />
n 21% NIH industry<br />
n 1% o<strong>the</strong>r<br />
TYPE OF TRIAL<br />
TYPE OF TRIAL<br />
O<strong>the</strong>r<br />
Industry<br />
Non-interventional<br />
Non-interventional<br />
O<strong>the</strong>r<br />
Industry<br />
O<strong>the</strong>r peer-rev<br />
NIH<br />
O<strong>the</strong>r<br />
Industry<br />
O<strong>the</strong>r peer-reviewed (<strong>from</strong> government and foundations)<br />
O<strong>the</strong>r peer-re<br />
Gastrointestinal<br />
Gastrointestinal<br />
Breast<br />
Breast<br />
Genitourinary<br />
Genitourinary<br />
Lung<br />
Lung<br />
Hematologic<br />
Hematologic<br />
Neurological<br />
Neurological<br />
Head & Neck<br />
Head & Neck<br />
Endocrine<br />
Endocrine<br />
Skin<br />
Skin<br />
Gynecologic<br />
Gastrointestinal<br />
Gynecologic<br />
Orthopedic<br />
Breast<br />
Orthopedic<br />
Unknown<br />
Genitourinary<br />
Unknown<br />
O<strong>the</strong>r<br />
Lung<br />
O<strong>the</strong>r<br />
Hematologic<br />
Neurological<br />
Head & Neck<br />
Endocrine<br />
Skin<br />
Gynecologic<br />
Orthopedic<br />
Unknown<br />
O<strong>the</strong>r<br />
2006<br />
2007<br />
2008<br />
neW patients by cancer type: fy2008*<br />
Breast<br />
2005<br />
Genitourinary<br />
2005<br />
2006<br />
Lung<br />
2006<br />
Hematologic<br />
2007<br />
2007<br />
Neurological<br />
2008<br />
2008<br />
Head & Neck<br />
Endocrine<br />
P A T I E N T S E N R O L L E D<br />
Data are for calendar year spans unless o<strong>the</strong>rwise noted.<br />
8000<br />
7000<br />
6000<br />
5000<br />
2000<br />
Skin<br />
0<br />
Gynecologic<br />
*Does not include philanthropic support.<br />
clinical trial enrollment:<br />
2008<br />
Interventional<br />
Orthopedic<br />
TYPE OF TRIAL<br />
Unknown<br />
Non-interventional<br />
O<strong>the</strong>r<br />
*fiscal year is July 1, 2007 through June 30, 2008.<br />
NIH<br />
O<strong>the</strong>r<br />
Industry<br />
O<strong>the</strong>r pe<br />
NIH<br />
In<br />
O<br />
N
honor roll of donors<br />
Lombardi’s successes, <strong>from</strong> <strong>the</strong> growth of new initiatives to <strong>the</strong> latest advances in<br />
patient care, would not be possible without <strong>the</strong> generous support of so many in <strong>the</strong><br />
community. We thank you all for generous contributions to <strong>the</strong> success of Lombardi<br />
in our fight against cancer, and recognize those gifts received during fiscal year<br />
2008 (July 2007 through June 2008).<br />
$100,000–$999,999<br />
American Cancer Society<br />
Avon foundation<br />
The Children’s Cancer foundation<br />
Marshall B. Coyne foundation<br />
Bernard & Sarah Gewirz<br />
foundation, Inc.<br />
Marvin and Jo Anne McIntyre family<br />
foundation<br />
NfL Charities<br />
Prevent Cancer foundation<br />
Prince Charitable Trusts<br />
elisabeth von Matsch through <strong>the</strong><br />
edwin H. richard Trust<br />
Dr. Scholl foundation<br />
$10,000–$99,999<br />
3M Company Inc.<br />
Tina S. Alster, M.D.<br />
American Association for Cancer<br />
research<br />
American Institute for Cancer research<br />
Ms. rebecca M. Bednarik<br />
Beers + Cutler, PLLC<br />
Carefirst BlueCross BlueShield<br />
Cherry Blossom Breast Cancer fund<br />
Ms. Patricia Loughrey and Mr. John D.<br />
Claringbould<br />
The Clark Charitable foundation<br />
Comcast financial Agency Corporation<br />
DBTS Inc.<br />
Donohue family foundation<br />
Douglas Development<br />
Mary Joy Drass, M.D.<br />
Drueding foundation<br />
ermenegildo Zegna Group<br />
first Potomac realty Investment, LP<br />
r. J. fox foundation<br />
Dr. and Mrs. richard C. fuisz<br />
Dr. and Mrs. Arthur f. furman<br />
Genworth financial<br />
Giant food LLC<br />
Global Transportation Systems Inc.<br />
Go Bo fund<br />
Go4<strong>the</strong>Goal foundation<br />
Ms. Judith G. Gordon<br />
Heritage Charity Classic<br />
Stuart and Daphne Himelfarb<br />
Hope On Wheels Hyundai Dealers<br />
Integral Nuclear Associates, LLC<br />
Mr. and Mrs. John Jaffe<br />
The JBG Companies<br />
The Joseph e. and Marjorie B. Jones<br />
foundation<br />
Governor and Mrs. francis A. Keating, II<br />
Mr. Neil S. Kishter<br />
Mr. William H. Klinedinst<br />
Nathan Landow family Limited<br />
Partnership<br />
Jeffrey and Mary Lane<br />
ralph and ricky Lauren<br />
Macy’s Inc.<br />
MedStar Health Inc.<br />
Mr. and Mrs. Herbert S. Miller<br />
Miller’s furs<br />
National Cancer Prevention fund<br />
Mr. William Naughton<br />
Newman’s Own foundation<br />
Parkway Ventures Inc.<br />
Patty Pollotas fund Inc.<br />
Pink Skirts - Andy Horne<br />
Polo ralph Lauren foundation<br />
The John and Jane Powers foundation<br />
Mr. Perry D. Quick<br />
Sylvia ritzenberg Charitable Trust<br />
Mr. and Mrs. frederick D. Schaufeld<br />
rolls-royce<br />
The Hon. and Mrs. ronald rosenfeld<br />
rTKL Assoc., Inc.<br />
Ms. Maria Stella ruggirello<br />
Mrs. frances Schafer<br />
Mr. Michael e. Schaufeld<br />
Seagears family foundation<br />
Liddy Shriver Sarcoma Initiative fund<br />
Smithfield foods Inc.<br />
Swing fore <strong>the</strong> Cure<br />
Mr. and Mrs. John r. Thompson III<br />
Norma Kline Tiefel foundation<br />
Tishman Speyer Properties, LP<br />
UnitedHealthCare Services Inc.<br />
Mrs. Anne C. Whittington<br />
$1,000–$9,999<br />
Abitibi-Consolidated Company of<br />
Canada<br />
The Abramson family foundation<br />
Acacia federal Savings Bank<br />
AeP <strong>Georgetown</strong> fraternity<br />
AgencyOne Insurance Marketing Group<br />
Albert & Lillian Small foundation<br />
Mr. and Mrs. William B. Alsup<br />
American foundation<br />
The American Legacy foundation<br />
American Trucking Associations Inc.<br />
Mr. and Mrs. richard Amons<br />
Susan M. Ascher, M.D.<br />
The Baker foundation<br />
Ms. Sarah e. Baker<br />
Bancroft Associates, PLLC<br />
Ms. Carie-Ann D. Barrow<br />
Gabriel Battista<br />
Baystate financial Services LLC<br />
Mr. John A. Beck<br />
Bender foundation, Inc.<br />
Mr. and Mrs. robert H. Benna<br />
The Hon. and Mrs. Stuart A. Bernstein<br />
Blake real estate, Inc<br />
Jay and ellen Bloom fund<br />
Mr. and Mrs. Jay B. Bloom<br />
Boland<br />
Mr. and Mrs. Benjamin W. Boley<br />
Mr. William J. Boylan<br />
BP Corporation North America Inc.<br />
Mr. Keith D. Brown<br />
Mrs. Peggy S. Brown<br />
Salvatore and Cynthia Bruno<br />
Mr. and Mrs. Thomas L. Buckmaster<br />
Mr. and Mrs. robert V. Cahill<br />
Dr. and Mrs. Nils W. Carlson<br />
e. eugene Carter foundation<br />
Mr. Z. J. Chelec<br />
Cissel-Saxon Unit No. 41/American<br />
Legion Auxiliary<br />
Mr. and Mrs. George P. Clancy<br />
Clark Construction Group, LLC<br />
Click Wine Group<br />
Ms. Deborah e. Cochrane<br />
Mr. richard S. Cohen<br />
23
24<br />
honor roll of donors<br />
Mr. Sherman L. Cohn<br />
Congressional Institute Inc.<br />
Core Capital Partners<br />
Corporate Office Properties Trust<br />
Corstone Capital Corporation<br />
The Hon. Carol T. Crawford and Mr.<br />
ronald Crawford<br />
Daffodils & Diamonds<br />
DBI Architechts Inc.<br />
Mr. David Deckelbaum<br />
Mr. and Mrs. Mark O. Decker, Sr.<br />
Captain Victor Delano, USN (ret)<br />
Dr. and Mrs. Daniel L. Dellatore<br />
Ms. Jo Ann Grainger and Mr. John<br />
Devlin<br />
Ms. Kerry Diamond<br />
Mr. and Mrs. robert r. Dickson<br />
Ms. Judith Diesenhaus<br />
Joanna ritcey-Donohue and William<br />
Donohue<br />
Mrs. Jeanne C. Donovan<br />
Ms. Victoria J. Doran<br />
The Max and Victoria Dreyfus<br />
foundation<br />
Mr. and Mrs. Ken Druskin<br />
Mr. Seth Dudley<br />
Mr. and Mrs. Albert J. Dwoskin<br />
e. Goodwin & Sons Inc.<br />
edison electric Institute<br />
american airLines<br />
Mr. Douglas egan<br />
The Jonathan S. & Patricia G. england<br />
foundation<br />
eTA<br />
Mrs. Jeanette Perno fenty<br />
Jean-Marie ferenz and raul fernandez<br />
Mr. Douglas fleit<br />
fleming Jenkins Vineyards & Winery<br />
fosterSoft, Inc.<br />
Les francis Photography<br />
Dr. Irma and Mr. richard frank<br />
Mr. Scott A. frankel<br />
freddie Mac foundation<br />
Ms. Linda fuselier and Mr. Chris Ogden<br />
The Hon. and Mrs. Arthur J. Gajarsa<br />
Mary L. Gardner, M.D.<br />
Ms. Mickela D. Gay<br />
Mr. and Mrs. Carl S. Gewirz<br />
Ms. Karen e. Griffith Gilbreath and Mr.<br />
Jim Sowell<br />
Ms. Lisa W. Gill<br />
Gladstone Management Corporation<br />
The Glenstone foundation<br />
Mrs. Gretchen Meister Gorog<br />
Mr. James B. Graham<br />
The Hon. and Mrs. William Graves<br />
Mr. William f. Greaney<br />
Greater Washington Commercial<br />
Association of realtors<br />
for nearly two decades, american airlines has supported lombardi with more than<br />
$250,000 in airline tickets. as <strong>the</strong> official airline for both <strong>the</strong> Women and Wine and<br />
<strong>the</strong> men’s event in 2008, american airlines flights were auctioned and raffled to help<br />
raise funds for <strong>the</strong> cancer center.<br />
<strong>the</strong> Women & Wine event is a high profile occasion that affords a prestigious<br />
group of women <strong>the</strong> opportunity to enjoy an evening among <strong>the</strong>ir peers, in an upscale<br />
dinner setting, while raising significant dollars in support of women’s cancers. tickets<br />
<strong>from</strong> american airlines were offered as door prizes to lucky attendees. <strong>the</strong> men’s<br />
event, focusing on prostate cancer awareness, was also sponsored by american<br />
airlines.<br />
“american airlines has long been an avid supporter of <strong>the</strong> lombardi compre-<br />
hensive cancer center. We traditionally look for organizations that are totally com-<br />
mitted to providing unyielding support and relief to <strong>the</strong> communities,” said gerald<br />
mcgaughey, regional sales <strong>director</strong> for <strong>the</strong> mid-atlantic. “lombardi has been relentless<br />
and unwavering in <strong>the</strong>ir contributions to patient care and cancer research. We<br />
truly appreciate <strong>the</strong> commitment and dedication that <strong>the</strong>y continue to provide.”<br />
american airlines has also been <strong>the</strong> official airline of <strong>the</strong> lombardi gala since<br />
2005. <strong>the</strong> company has donated dream vacations to <strong>the</strong> live auction, including all<br />
expenses paid first class tickets to shanghai, london, and <strong>the</strong> galapagos islands.<br />
Mr. and Mrs. Arthur Greenberg<br />
Mr. and Mrs. richard O. Haase<br />
A. J. Harris, II Charitable foundation<br />
Harvey-Cleary Builders<br />
Ms. Joyce Havard<br />
Mr. and Mrs. John T. Hazel, Jr.<br />
Health Insurance Specialists<br />
Heart Sing foundation<br />
Ms. elizabeth C. Arbogast and Mr.<br />
Walter L. Hill<br />
Hogan & Hartson, LLP<br />
The Home Depot USA<br />
Mr. Steven B. Hopping<br />
Mr. and Mrs. Joseph f. Horning<br />
Mr. George C. Howell, III<br />
Hunton & Williams, LLP<br />
Ms. Jane L. Sprol Hurley<br />
Independent Project Analysis Inc.<br />
Innovative Management & Technology<br />
Approaches Inc.<br />
Mr. and Mrs. Benjamin r. Jacobs<br />
Jamaican Women of Washington Inc.<br />
Jeff Lubin Studios<br />
Johnson & Johnson<br />
Clarion e. Johnson, M.D.<br />
Ms. rosalind Juo<br />
K & L Gates<br />
Mr. Joseph W. Kaempfer, Jr.<br />
Mr. and Mrs. Joe Kampf
doo Wop concert for cancer<br />
more than 60 doo Wop and rock ‘n’ roll performers <strong>from</strong> across <strong>the</strong> country took <strong>the</strong> stage at<br />
<strong>the</strong> district’s historic Warner <strong>the</strong>atre on saturday, september 6, 2008 to benefit <strong>the</strong> pancreatic<br />
and prostate programs at <strong>the</strong> georgetown lombardi comprehensive cancer center. over 1,500<br />
guests were in attendance at <strong>the</strong> first-ever lombardi doo Wop concert for cancer.<br />
<strong>the</strong> event raised $600,000 and honored <strong>the</strong> memory of commercial real estate advisor and<br />
doo Wop fan eddie geisinger, who lost his battle with pancreatic cancer in 2001 at <strong>the</strong> age of<br />
55. marvin mcintyre of smith barney was <strong>the</strong> presenting sponsor of <strong>the</strong> concert with a gift of<br />
$100,000.<br />
“prostate and pancreatic cancers affect thousands of americans each year. With <strong>the</strong> support<br />
of <strong>the</strong> community with events like this, lombardi will continue to be able to conduct world-class,<br />
cutting-edge research and will provide superb, compassionate patient care that builds on its base<br />
of research excellence,” said louis m. Weiner, md, <strong>director</strong> of lombardi.<br />
Mr. Brian L. Katz<br />
Timothy Dyk & Sally Katzen family fund<br />
Mr. and Mrs. Howard J. Kaufman<br />
Keller & Heckman, LLP<br />
Mr. and Mrs. James J. Kelley<br />
Mr. e. Douglas Kenna<br />
Kirkland & ellis, LLP<br />
Korzeniewski family foundation<br />
Mr. and Mrs. robert Korzeniewski<br />
Kovak foundation<br />
Labat-Anderson, Incorporated<br />
eugene W. and Gloria Landy family<br />
foundation<br />
Mr. and Mrs. Jerome Lauren<br />
Ms. Yen-Yao Lee<br />
Mr. and Mrs. Craig Lemle<br />
Annette M. & Theodore N. Lerner family<br />
foundation Inc.<br />
Mr. Michael J. Lindner<br />
The Livingston Group, LLC<br />
Sally and Vincent Lombardi<br />
Michael P. Lorek, M.D.<br />
The Loyola foundation, Inc.<br />
Mr. and Mrs. J. Christopher Lynch<br />
Magna Carta foundation<br />
The Malek family Charitable Trust<br />
Dimitri and Peggy Mallios<br />
Ms. Theresa D. Mangen<br />
Ms. Ca<strong>the</strong>rine Marich<br />
Marks Insurance & Associates Inc.<br />
Mr. David S. Martin<br />
The Maxwell Taylor foundation<br />
Irving May & edith H. May foundation<br />
Mayer Brown, LLP<br />
Marybeth McAteer, M.D.<br />
Cathy and Scot McCulloch<br />
Mrs. Mary M. McDonough Connolly<br />
Sammy Sax and <strong>the</strong> MDs perform at Lombardi’s Doo Wop Concert �<br />
Kevin G. McGeagh, M.D.<br />
Michelle Dupont Inc.<br />
Mr. Andrew L. Moose<br />
Morgan Stanley Matching Gifts Program<br />
Mr. James Muldoon<br />
ellen and Jim Myerberg<br />
National Association of Chain Drug<br />
Stores, Inc.<br />
The National Italian American foundation<br />
National rehabilitation Hospital<br />
Ms. Diane Newberg<br />
Newmark Knight frank<br />
Mr. and Mrs. Henry e. Nichols<br />
Nolan family Charitable foundation Inc.<br />
Mr. and Mrs. Phillip G. Norton<br />
Oakdale emory United Methodist Church<br />
The Terrence & Margaret O’Donnell<br />
Charitable Gift fund<br />
The Otto Company<br />
The Owen family foundation<br />
Mr. and Mrs. Victor W. Palmer<br />
PCC-ACNA<br />
Pfizer<br />
PGA Tour, Inc.<br />
Pillsbury<br />
Plastic and reconstructive Surgery<br />
Ms. Joan Plotkin<br />
John J. Pohanka family foundation<br />
Mr. Charles A. Post<br />
Potomac electric Power Company<br />
Potomac Partners<br />
Mr. Charles Owen Prince, III<br />
Property Capital, LLC<br />
randall Hagner, Ltd.<br />
robyn redfield<br />
Phillip renfrow<br />
republic Title, Inc.<br />
The reserve<br />
retirement Planners and Administrators, Inc.<br />
Mr. Ken rietz<br />
The Michael L. riordan fund<br />
Mr. and Mrs. Paul Anthony ritacco<br />
James & Trisha ritzenberg<br />
The rLJ Companies, LLC<br />
roadcap family Limited Partnrship<br />
Mr. robert K. robbins<br />
Carter and Jackie roberts<br />
Ms. Terri robinson<br />
Mr. Samuel G. rose<br />
Ms. rosemary rosso<br />
ryland<br />
S. Kann Sons Company foundation, Inc.<br />
Saint Mary’s<br />
Shahram Salemy, M.D.<br />
Mr. Gene Samburg<br />
Mr. and Mrs. John Sanders<br />
Mr. Mitchell N. Schear<br />
Mrs. Gerda Schechter<br />
The Scherr family fund<br />
Mr. Bob Schieffer<br />
Ms. Julie Burt Schuelke<br />
Paul and randi Schweitzer<br />
Science Applications International Corp.<br />
(SAIC)<br />
Second Chance employment Services<br />
Nancy and Ali Sevin<br />
The Shafran family foundation<br />
Shapiro, Lifschitz and Schram, PC<br />
Mr. and Mrs. Bernard M. Shapiro<br />
Mr. Donald J. Shepard<br />
Ms. elizabeth Shepard and Mr. Terrence<br />
D. Straub<br />
Peter G. Shields, M.D.<br />
Mr. Patrick Shooltz<br />
25
26<br />
honor roll of donors<br />
Mr. Thomas C. Shooltz<br />
Mrs. Winifred Shreeves<br />
Shulman, rogers, Gandal, Pordy &<br />
ecker, PA<br />
Mr. robert Silverman<br />
Caren Singer foundation for Breast<br />
Cancer research<br />
Mr. Terry Slease<br />
Jennifer and erik Smulson<br />
Mr. Tony Snow<br />
Mr. and Mrs. Mitchell Spaid<br />
Mr. Charles M. Steiner<br />
Stephen G. Yeonas Company<br />
Mr. Guy Thomas Steuart, II<br />
Studley, Inc.<br />
Ms. Kathleen Murphy and Mr. William<br />
Sudow<br />
SunTrust Mid-Atlantic foundation<br />
Symantec Corporation<br />
elizabeth Tanzi, M.D.<br />
Mr. and Mrs. Gary f. Temple<br />
Thomas ru<strong>the</strong>rfoord Inc.<br />
Ms. Susan M. Thomas<br />
Timbervest, LLC<br />
robert e. and Anne P. Torray family<br />
foundation<br />
United Bank Card Inc.<br />
United States Steel Corporation<br />
U.S. Chamber of Commerce<br />
Mr. and Mrs. Jonathan r. Veum<br />
Vornado/Charles e. Smith<br />
Wachovia Corporation<br />
The Washington Post Company<br />
Washington real estate Investment<br />
Trust<br />
Washington Wellness Institute, PC<br />
Watt, Tieder, Hoffar & fitzgerald, LLP<br />
Wilkes, Artis, Hedrik & Lane, Chtd.<br />
Williams and Connolly<br />
Mrs. Agnes N. Williams<br />
Windows Catering Company<br />
Mr. and Mrs. Stephen Witort<br />
Mr. David C. Wright<br />
Ms. elizabeth Jane Yeates<br />
Mr. Stephen Thomas Yelverton<br />
Mr. and Mrs. John Yochelson<br />
Mr. and Mrs. Shariar Zaimi<br />
Mr. richard Zitelman<br />
$500–$999<br />
Ms. Tanya Potter Adler and<br />
Mr. Howard B. Adler<br />
AIG<br />
Mr. and Mrs. richard S. Alexander<br />
Mr. Charles M. Anopf<br />
APSP - Middle Atlantic Chapter<br />
Velvie Pogue and Alfred Ashford<br />
The Association Of Boarding Schools<br />
Mr. Wade H. Atkinson, Jr.<br />
Ms. Kellie Ballard<br />
Mr. and Mrs. richard D. Bean<br />
Ms. Jane C. Bergner<br />
<strong>the</strong> richard von matsch endoWed chair<br />
in experimentaL <strong>the</strong>rapuetics Milton Brown, MD, PhD �<br />
milton l. brown, md, phd, was named <strong>the</strong> inaugural edwin h. richard and elisabeth<br />
richard von matsch endowed chair in experimental <strong>the</strong>rapeutics on January 17th, 2008.<br />
dr. brown leads georgetown university’s drug discovery program, which aims to narrow<br />
<strong>the</strong> gap between <strong>the</strong> discovery of tools that improve our knowledge of diseases and <strong>the</strong><br />
number of new <strong>the</strong>rapies “translated” to <strong>the</strong> bedside.<br />
<strong>the</strong> endowed chair is part of a $4.5 million gift <strong>from</strong> mrs. elisabeth richard von<br />
matsch and <strong>the</strong> richard family to support clinical and translational research in drug discovery<br />
and development at georgetown university medical center. dr. brown has devoted<br />
his career to developing drugs to treat diseases ranging <strong>from</strong> cancer to seizure disorders<br />
to hypertension. as chair, he will continue to lead georgetown’s thriving drug discovery<br />
program in its mission to develop lifesaving diagnostics and <strong>the</strong>rapeutics.<br />
“i am really grateful for <strong>the</strong> generous support of <strong>the</strong> richard family,” said dr. brown,<br />
who is an associate professor of oncology and neuroscience. “<strong>the</strong>ir generosity will help<br />
us solidify <strong>the</strong> foundation of one of <strong>the</strong> only academic drug discovery programs in <strong>the</strong><br />
country, leading to <strong>the</strong> creation of many new compounds aimed at helping people live<br />
healthier lives.”<br />
Bishop Ireton High School<br />
Bonner, Kiernan, Trebach & Crociata<br />
Mr. Michael J. Bowen<br />
Ms. Doris J. Brown<br />
Mr. and Mrs. William L. Bryant<br />
Mr. Quang Minh Bui<br />
Mr. fred Caesar<br />
The Morris and Gwendolyn Cafritz<br />
foundation<br />
Mr. and Mrs. Kenneth Carpenter<br />
Mr. and Mrs. James Carr<br />
Mr. roasrio Castioni<br />
Mr. Wayman W. Cheatham<br />
Ms. Julia Ciorletti<br />
Peter I. and Jane M. Cohen fund<br />
Jessie Margolis and Thomas Coleman<br />
Comcast<br />
Mr. David M. Curry<br />
Mr. and Mrs. robert L. Curtis<br />
Dan Pacific Hotel Seattle<br />
The Hon. Samuel H. Dean<br />
Mrs. Carolyn Deaver<br />
Mr. Michael Stephen Diamant<br />
Mr. and Mrs. Jeffrey S. Distenfeld<br />
Cornell Douglas foundation Inc.<br />
Mrs. Joan W. Doyle<br />
Mr. edmund C. Duffy<br />
exxonMobil Corporation<br />
Mr. richard A. feinstein<br />
Mr. John D. ferguson<br />
Dr. and Mrs. Gregory John Gagnon
John potter<br />
on friday, october 3, 2008, over 100 family members, friends, and colleagues<br />
ga<strong>the</strong>red to honor John f. potter, md, founder and first <strong>director</strong> of <strong>the</strong> lombardi<br />
comprehensive cancer center. dr. potter, a nationally recognized specialist in oncology<br />
and surgery, served <strong>the</strong> georgetown university medical community for 60 years.<br />
during his career, dr. potter published many scholarly articles, authored a book, and<br />
was president of <strong>the</strong> association of american cancer institutes.<br />
<strong>the</strong> event also marked <strong>the</strong> inauguration of <strong>the</strong> John f. potter distinguished<br />
lecture series named in his honor. John e. niederhuber, md, <strong>director</strong> of <strong>the</strong> national<br />
cancer institute, and a nationally renowned surgeon and researcher, was <strong>the</strong> keynote<br />
speaker. <strong>the</strong> topic of dr. niederhuber’s lecture was “frontiers of cancer research.”<br />
in 1970, dr. potter became <strong>the</strong> first <strong>director</strong> of <strong>the</strong> lombardi cancer center, which<br />
he founded in memory of <strong>the</strong> legendary green bay packers and Washington redskins<br />
football coach vincent t. lombardi. during his 20 year tenure, <strong>the</strong> center received its<br />
comprehensive designation in 1974.<br />
Dr. Potter with Lombardi’s current <strong>director</strong>, Louis Weiner, at <strong>the</strong> ceremony honoring his leadership �<br />
The Hon. Marvin J. Garbis<br />
Ms. elise A. Gemeinhardt<br />
Mr. and Mrs. Wayne B. Gifford<br />
Mr. and Mrs. H. Jason Gold<br />
Dr. and Mrs. John f. Griffith<br />
Mr. and Mrs. Bill r. Gulsby<br />
Mr. David Svend Gusmer<br />
Mr. John Harkrider<br />
Mr. C. edward Harshbarger<br />
Ms. Anne Hatfield and Mr. Howard Weir<br />
Ms. Heidi Hatfield<br />
Mr. Gary C. Hufbauer<br />
Mr. and Mrs. Michael J. Hunter<br />
Ms. Jennifer Hyde and Mr. David M.<br />
Bronstein<br />
Mrs. Jean M. Iker<br />
International Paper employees Community<br />
fund<br />
Mrs. Anne Lise A. Jones<br />
Mr. Dan Katan<br />
Mr. and Mrs. James D. Kaufmann<br />
Mr. Brian J. Kearney<br />
Mr. and Mrs. Allen e. Kibat<br />
Dr. and Mrs. John J. Kishel<br />
Mrs. Laura S. Kopp<br />
Korea economic Institute<br />
Mr. Glen Kruglak<br />
Landmark Partners Inc.<br />
Mr. and Mrs. Daniel M. Lebey<br />
Mr. and Mrs. Thomas f. Lechner<br />
Ms. Shinwha Lee<br />
Mr. and Mrs. Marc Levy<br />
Ms. elizabeth O. Liboa-farrow<br />
Mr. and Mrs. Gregory W. Lindenstruth<br />
Mr. robert Low, Jr.<br />
Ms. Patricia e. Maddalone<br />
Peri N. Mahaley, esq.<br />
Manekin, LLC<br />
Mr. Patrick A. Mannion<br />
Ms. Ahriq Marshall<br />
Dr. and Mrs. John L. Marshall<br />
Ms. Loretta M. Marshall<br />
Mr. robert W. Mayer<br />
Mr. Barry McDowell<br />
H. Thomas McDuffie and Barbara Schaefer<br />
McDuffie<br />
Ms. Lynn McKinley-Grant<br />
Mr. and Mrs. David Jan Mitchell<br />
Mr. and Mrs. Toby Moffett<br />
Ms. Kristen Morris<br />
Mr. and Mrs. robert S. Mueller, III<br />
Nardi Construction Inc.<br />
Mr. Marcus Noland<br />
Mrs. elizabeth Orr<br />
The PAZ fund<br />
Mrs. Janet K. Phillips<br />
Mrs. Carole J. Poling<br />
Ms. Vivianne Pommier<br />
Mr. Sanjiv Prakash<br />
Mr. robert H. Pry<br />
Mr. and Mrs. Stephen Pryor<br />
Mr. Domenick ricci<br />
Dr. Maryse robert<br />
Mr. and Mrs. Kenneth A. Samet<br />
Mrs. Patricia S. Scanlon<br />
Drs. Julian Moiseiwitsch and françoise<br />
Sellier-Moiseiwitsch<br />
Mr. and Mrs. richard L. Shafer<br />
ShawnCoulson, LLP<br />
Mr. Daniel f. Sheehan<br />
Sherwin-Williams/Duron<br />
Ms. Laurent P. Sirois<br />
Mr. David Sittler<br />
Dr. Genevieve Brunet Smith<br />
Mr. and Mrs. Howard W. Solomon<br />
Ms. Diana Sullivan<br />
Mr. Daniel M. Threlkel<br />
The M.W. and frances J. Tilghman fund<br />
Ms. Karla Underwood<br />
Mr. Bailey G. Walsh<br />
Mr. and Mrs. Mat<strong>the</strong>w D. Ward<br />
Wiley rein, LLP<br />
Mr. David Wine<br />
Mr. and Mrs. Thomas W. Wood<br />
elizabeth and Kevin Wrege<br />
Mr. and Mrs. reynolds Young<br />
27
28<br />
honor roll of donors<br />
<strong>the</strong> prince charitabLe trusts<br />
<strong>the</strong> prince charitable trusts is a long-standing philanthropic partner of<br />
georgetown university, and a member of <strong>the</strong> prestigious 1789 society. since<br />
1998, <strong>the</strong>ir focus has been on creating programming to enhance staff morale<br />
at lombardi and georgetown university hospital. With initial grants of<br />
$50,000 to <strong>the</strong> palliative care and <strong>the</strong> arts and humanities programs, and a<br />
subsequent commitment of $500,000, <strong>the</strong> prince charitable trusts is providing<br />
for <strong>the</strong> highest possible quality of life for patients and staff at lombardi<br />
and <strong>the</strong> hospital.<br />
according to nancy morgan, ma-tla, <strong>director</strong> of arts and humanities,<br />
“<strong>the</strong> prince trustees embrace a unique vision regarding <strong>the</strong> support of hospital<br />
staff as essential to optimal patient care. With <strong>the</strong>ir understanding and<br />
support, we have engaged our nurses, medical students, chaplains and o<strong>the</strong>r<br />
medical caregivers in arts activities that renew energy, instill a spirit of collaboration,<br />
and provide emotional expression—all essential to good health and<br />
good medical practice.”<br />
mr. and mrs. prince were inspired to provide support for <strong>the</strong>se programs<br />
through <strong>the</strong> prince charitable trusts because, “<strong>the</strong> contributions of <strong>the</strong> staff<br />
are so invaluable and so multi-faceted that we wanted to find a way of giving<br />
back to <strong>the</strong>m that enhances <strong>the</strong>ir health and well-being in equal measure. We<br />
believe this program honors our intentions.”<br />
A program supported by a grant <strong>from</strong> Prince helps staff members relieve stress through drumming. �<br />
Gifts in kind<br />
$10,000–$50,000<br />
American Airlines<br />
Sarah Boyer Jenkins & Associates<br />
$1,000–$9,999<br />
Bellagio resort<br />
Bermingham Photography<br />
The Breakers - Palm Beach<br />
Brown Jordan/elton Associates Inc.<br />
Cafe Oggi<br />
Carole roberts enterprises<br />
Century Designer Showroom<br />
The Clifton Inn<br />
Continental Jewelers<br />
Crate & Barrel<br />
Creative Parties<br />
Debevec Interiors Incorporated<br />
Duralee fabrics, Ltd.<br />
evelyn Brooks Designs<br />
executive 411<br />
f. Schumacher & Co.<br />
fitness Toge<strong>the</strong>r, Alexandria<br />
freed Photography Inc.<br />
The Greenbrier<br />
Gregory fine Portraits<br />
The Hay Adams Hotel<br />
Hela Spa<br />
The Henley Park Hotel<br />
Hilton Hawaiian Village<br />
John Hancock financial Services<br />
Key Title<br />
Jill Kirkpatrick and Tony Connor<br />
Justine Sancho Interior Design<br />
Klipsch Audio Technologies<br />
Dr. and Mrs. Stuart Kushel<br />
La Samanna<br />
Lancôme<br />
Lloyd-Meurer Portrait Studio of<br />
Potomac Village<br />
Dr. and Mrs. Csaba L. Magassy<br />
Mandalay Bay resort & Casino<br />
Marriott Wardman Park Hotel<br />
Michael - Cleary, LLC<br />
MLS Gallery<br />
Mohegan Sun<br />
Nina McLemore<br />
Nissan Pavilion<br />
Norfolk Sou<strong>the</strong>rn Corporation<br />
P & C Art<br />
The Hon. Bob Packwood<br />
Picture frame factory<br />
Ms. eliana Porath<br />
random Harvest<br />
The ritz-Carlton, Cancun<br />
The ritz-Carlton, Amelia Island<br />
The ritz-Carlton, Bachelor Gulch<br />
The ritz-Carlton, <strong>Georgetown</strong><br />
ritz-Carlton, Laguna Niguel<br />
ritz-Carlton Lake Las Vegas<br />
The ritz-Carlton Leadership Center<br />
The ritz-Carlton New York, Battery<br />
Park<br />
The ritz-Carlton Orlando, Grande<br />
Lakes<br />
ritz-Carlton, Powerscourt, County<br />
Wicklow<br />
The ritz-Carlton San Juan Hotel, Spa<br />
and Casino<br />
rMA Worldwide Chauffered<br />
Transportation<br />
Mr. Joseph e. robert, Jr.<br />
rSVP Catering<br />
Sarah Boyer Jenkins & Associates<br />
Albert Shvilly Studio<br />
Sofitel Lafayette Square<br />
Sport & Health Clubs<br />
State Plaza<br />
Stroheim & roman<br />
Tiny Jewel Box<br />
Towne Silver & Goldsmith<br />
Versace<br />
Vespa Washington<br />
Washington Institute for Dentistry &<br />
Toxicology